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| 1 | Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier显示文摘AIM To investigate whether gut microbiota metabolite sodium butyrate(Na B)is an effective substance for attenuating non-alcoholic fatty liver disease(NAFLD)and the internal mechanisms.METHODS Male C57BL/6J mice were divided into three groups,normal control were fed standard chow and model group were fed a high-fat diet(HFD)for 16 wk,the intervention group were fed HFD for 16 wk and treated with Na B for 8 wk.Gut microbiota from each group were detected at baseline and at 16 wk,liver histology were evaluated and gastrointestinal barrier indicator such as zonula occluden-1(ZO-1)were detected by immunohistochemistry and realtime-PCR,further serum or liver endotoxin were determined by ELISA and inflammation-or metabolism-associated genes were quantified by real-time PCR.RESULTS Na B corrected the HFD-induced gut microbiota imbalance in mice,while it considerably elevated the abundances of the beneficial bacteria Christensenellaceae,Blautia and Lactobacil us.These bacteria can produce butyric acid in what seems like a virtuous circle.And butyrate restored HFD induced intestinal mucosa damage,increased the expression of ZO-1 in small intestine,further decreased the levels of gut endotoxin in serum and liver compared with HF group.Endotoxin-associated genes such as TLR4 and Myd88,pro-inflammation genes such as MCP-1,TNF-α,IL-1,IL-2,IL-6 and IFN-γin liver or epididymal fat were obviously downregulated after Na B intervention.Liver inflammation and fat accumulation were ameliorated,the levels of TG and cholesterol in liver were decreased after Na B intervention,NAS score was significantly decreased,metabolic indices such as FBG and HOMA-IR and liver function indicators ALT and AST were improved compared with HF group.CONCLUSION Na B may restore the dysbiosis of gut microbiota to attenuate steatohepatitis,which is suggested to be a potential gut microbiota modulator and therapeutic substance for NAFLD. | Da Zhou Qin Pan Feng-Zhi Xin Rui-Nan Zhang Chong-Xin He Guang-Yu Chen Chang Liu Yuan-Wen Chen Jian-Gao Fan | 2017 | World Journal of Gastroenterology2017，23，1： | 77 |
| 2 | Removal of copper ions from aqueous solution by calcium alginate immobilized kaolin显示文摘Kaolin has been widely used as an adsorbent to remove heavy metal ions from aqueous solutions.However,the lower heavy metal adsorption capacity of kaolin limits its practical application.A novel environmental friendly material,calcium alginate immobilized kaolin (kaolin/CA),was prepared using a sol-gel method.The effects of contact time,pH,adsorbent dose,and temperature on Cu 2+ adsorption by kaolin/CA were investigated.The Langmuir isotherm was used to describe the experimental adsorption,the maximum Cu 2+ adsorption capacity of the kaolin/CA reached up to 53.63 mg/g.The thermodynamic studies showed that the adsorption reaction was a spontaneous and endothermic process. | Yanhui Li Bing Xia Quansheng Zhao Fuqiang Liu Pan Zhang Qiuju Du DechangWang Da Li ZonghuaWang Yanzhi Xia | 2011 | Journal of Environmental Sciences2011，23，3： | 14 |
| 3 | Experimental study on mechanism and protection of stress ulcer produced by explosive noise显示文摘INTRODUCTIONExplosivenoisemayproduceanenormousadverseeffectonhumanbodyandmind.Ithasbeenknownthatpepticulceroccuredmuchmorefre... | LIU Guo Shi 1, HUANG Yu Xin 1, LI Shuan Wei 2, PAN Bo Rong 3, WANG Xin 1, SUN Da Yong 1 and WANG Qing Li 1 | 1998 | World Journal of Gastroenterology1998，4，6： | 13 |
| 4 | Efficacy and safety of Shaoyang Xibi decoction in patients with knee osteoarthritis:a multi-center,single-blind,randomized controlled trial显示文摘PURPOSE: To observe the efficacy and safety of Shaoyang Xibi decoction(SYXBD) in patients with knee osteoarthritis(KOA), and to verify that the theory of 'Shaoyang dominating bone' in Traditional Chinese Medicine(TCM) can be applied to KOA treatment.METHODS: Participants were randomly allocated to two groups: SYXBD(treatment group, n = 66)and Meloxicam(control group, n = 66). Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) and 36-Item Short Form Health Survey(SF-36) were used to assess efficacy before the treatment and 8 weeks after the treatment.RESULTS: Baseline data before the treatment between the two groups were similar. The WOMAC scores significantly decreased and the SF-36 scores significantly increased after 8-week treatment in both groups compared with before the treatment(P < 0.05). SYXBD significantly decreased pain scores(P < 0.001), physical function scores(P <0.001) and the total scores(P < 0.001) in WOMAC compared to Meloxicam. SYXBD significantly improved physical function(P = 0.021), bodily pain(P = 0.002) and general health(P = 0.014), with no significant difference in role emotional(P = 0.053),role physical(P = 0.517), vitality(P = 0.241), social function(P = 0.712) and mental health(P = 0.800)in SF-36 compared to Meloxicam. No adverse events were reported in the treatment group while13 adverse events happened in the control group during the study.CONCLUSION: SYXBD, prepared based on the theory of 'Shaoyang dominating bone', has a better curative efficay and safety in patients with KOA compared with Meloxicam. The TCM theory of 'Shaoyang dominating bone' may be useful in KOA treatment. | Si Yuhao Ma Yong Guo Yang Pan Yalan Zheng Suyang Xu Guihua Da Weiwei Xu Lili | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 11 |
| 5 | mi R-192-5p regulates lipid synthesis in non-alcoholic fatty liver disease through SCD-1显示文摘AIM To evaluate the levels of mi R-192-5 p in non-alcoholic fatty liver disease(NAFLD) models and demonstrate the role of mi R-192-5 p in lipid accumulation. METHODS Thirty Sprague Dawley rats were randomly divided into three groups, which were given a standard diet, a high-fat diet(HFD), and an HFD with injection of liraglutide. At the end of 16 weeks, hepatic mi R-192-5 p and stearoyl-Co A desaturase 1(SCD-1) levels were measured. Mi R-192-5 p mimic and inhibitor and SCD-1 si RNA were transfected into Huh7 cells exposed to palmitic acid(PA). Lipid accumulation was evaluated by oil red O staining and triglyceride assays. Direct interaction was validated by dual-luciferase reporter gene assays.RESULTS The HFD rats showed a 0.46-fold decrease and a 3.5-fold increase in hepatic mi R-192-5 p and SCD-1 protein levels compared with controls, respectively, which could be reversed after disease remission by liraglutide injection(P < 0.01). The Huh7 cells exposed to PA also showed down-regulation and up-regulation of mi R-192-5 p and SCD-1 protein levels, respectively(P < 0.01). Transfection with mi R-192-5 p mimic and inhibitor in Huh7 cells induced dramatic repression and promotion of SCD-1 protein levels, respectively(P < 0.01). Luciferase activity was suppressed and enhanced by mi R-192-5 p mimic and inhibitor, respectively, in wild-type SCD-1(P < 0.01) but not in mutant SCD-1. Mi R-192-5 p overexpression reduced lipid accumulation significantly in PA-treated Huh7 cells, and SCD-1 si RNA transfection abrogated the lipid deposition aggravated by mi R-192-5 p inhibitor(P < 0.01).CONCLUSION This study demonstrates that mi R-192-5 p has a negative regulatory role in lipid synthesis, which is mediated through its direct regulation of SCD-1. | Xiao-Lin Liu Hai-Xia Cao Bao-Can Wang Feng-Zhi Xin Rui-Nan Zhang Da Zhou Rui-Xu Yang Ze-Hua Zhao Qin Pan Jian-Gao Fan | 2017 | World Journal of Gastroenterology2017，23，46： | 10 |
| 6 | Cloned pigs derived from somatic cell nuclear transferembryos cultured in vitro atlow oxygen tension显示文摘Pig cloning has great potential to human xenotransplantation. The present study was designed to establish a more efficient system for producing cloned pigs by somatic cell nuclear transfer (SCNT). Our approach was as follows: SCNT embryos were reconstructed by using fetal fibroblasts of Chinese miniature pig as donors and in vitro matured oocytes of prepubertal gilts as recipients. Reconstructed em- bryos were induced by electrical fusion/activation and cultured in BSA-containing North Carolina State University 23 medium (NCSU-23) or Porcine Zygote Medium (PZM-3) at the gas condition of 5% CO2, 7% O2, 88% N2. A total of 230 cloned embryos were transferred to three surrogate sows, producing three piglets. One of them is apparently healthy. The clonal provenance of the piglet was indicated by its coat color and confirmed by DNA microsatellite analysis. These results indicate that the use of in vitro matured oocytes from prepubertal gilts as recipient, combined with cloned embryos cultured at low oxygen tension is an effective way to produce cloned pigs. | PAN Dengke ZHANG Yunhai SUN Xiuzhu ZHANG Jian LI Xuyang LI Yan GU Zhiliang DA Yunping WU Changxin LI Ning | 2006 | Chinese Science Bulletin2006，51，7： | 8 |
| 7 | Change rules of a stratospheric airship's envelope shape during ascent process显示文摘Stratospheric airship is a special near-space air vehicle,and has more advantages than other air vehicles,such as long endurance,strong survival ability,excellent resolution,low cost,and so on,which make it an ideal stratospheric platform.It is of great significance to choose a reasonable and effective way to launch a stratospheric airship to the space for both academic research and engineering applications.In this paper,the non-forming launch way is studied and the method of differential pressure gradient is used to study the change rules of the airship's envelope shape during the ascent process.Numerical simulation results show that the head of the envelope will maintain the inflatable shape and the envelope under the zero-pressure level will be compressed into a wide range of wrinkles during the ascent process.The airship's envelope will expand with the ascent of the airship and the position of the zero-pressure level will move downward constantly.At the same time,the envelope will gradually form a certain degree of stiffness under the action of the inner and external differential pressure.The experimental results agree well with the analytical results,which shows that the non-forming launch way is effective and reliable,and the analytical method has exactness and feasibility. | Zhao Shuai Liu Dongxu Zhao Da Wu Gang Yin Shi Zhou Pan | 2017 | Chinese Journal of Aeronautics2017，30，2： | 7 |
| 8 | Trend and Interannual Variability of Chinese Air Pollution since 2000 in Association with Socioeconomic Development: A Brief Overview显示文摘Chinese air pollution has increased in this century along with the rapid socioeconomic development and resulting anthropogenic emissions. While recent emission control measures have shown encouraging results and have reduced the levels of sulfur dioxide and primary aerosols, the concentrations of other air pollutants continue to grow, particularly secondary pollutants including ozone and secondary aerosols. Meanwhile, a variety of intentional and unintentional socioeconomic events have temporarily changed the pace, and even the signs, of growth of air pollution. These events include the short-term emission restrictions imposed during the Sino-African Summit, the Beijing Olympics and Paralympics, the Shanghai World Exposition (Shanghai Expo), the Guangzhou Asian Olympics, and the Shenzhen Universiade, as well as the unintentional emission reductions associated with the recent economic recession and the annual Chinese New Year. This paper presents a brief overview of trends and temporary perturbations of Chinese air pollution since 2000, summarizing studies on anthropogenic emission inventories, atmospheric measurements, and inverse modeling. It concludes with recommendations for future research. | LIN Jin-Tai PAN Da ZHANG Rui-Xiong | 2013 | Atmospheric and Oceanic Science Letters2013，6，2： | 7 |
| 9 | A Method for the Environmental Quality Assessment of Surface Water Based on Artificial Neural Networks | YANG Guo\|dong\+1,\ PAN Da\|feng\+2,\ FAN Ying\|fang\+3 1.Dep. of Environmental Science, Shanxi Uni., Taiyuan 030006, China 2.Shanxi Academy of Agriculture Science, Taiyuan 030031, China 3.Institute of Molecular Science, Shanxi Uni., Taiyuan 030006, C | 2000 | Systems Science and Systems Engineering2000，10，1： | 7 |
| 10 | Trimethylamine N-oxide attenuates high-fat high-cholesterol dietinduced steatohepatitis by reducing hepatic cholesterol overload in rats显示文摘BACKGROUND Trimethylamine N-oxide (TMAO) has been shown to be involved in cardiovascular disease (CVD). However, its role in nonalcoholic steatohepatitis (NASH) is unknown. AIM To determine the effect of TMAO on the progression of NASH. METHODS A rat model was induced by 16-wk high-fat high-cholesterol (HFHC) diet feeding and TMAO was administrated by daily oral gavage for 8 wk. RESULTS Oral TMAO intervention attenuated HFHC diet-induced steatohepatitis in rats. Histological evaluation showed that TMAO treatment significantly alleviated lobular inflammation and hepatocyte ballooning in the livers of rats fed a HFHC diet. Serum levels of alanine aminotransferase and aspartate aminotransferase were also decreased by TMAO treatment. Moreover, hepatic endoplasmic reticulum (ER) stress and cell death were mitigated in HFHC diet-fed TMAOtreated rats. Hepatic and serum levels of cholesterol were both decreased by TMAO treatment in rats fed a HFHC diet. Furthermore, the expression levels of intestinal cholesterol transporters were detected. Interestingly, cholesterol influxrelated Niemann-Pick C1-like 1 was downregulated and cholesterol efflux-related ABCG5/8 were upregulated by TMAO treatment in the small intestine. Gut microbiota analysis showed that TMAO could alter the gut microbial profile and restore the diversity of gut flora. CONCLUSION These data suggest that TMAO may modulate the gut microbiota, inhibit intestinal cholesterol absorption, and ameliorate hepatic ER stress and cell death under cholesterol overload, thereby attenuating HFHC diet-induced steatohepatitis in rats. Further studies are needed to evaluate the influence on CVD and define the safe does of TMAO treatment. | Ze-Hua Zhao Feng-Zhi Xin Da Zhou Ya-Qian Xue Xiao-Lin Liu Rui-Xu Yang Qin Pan Jian-Gao Fan | 2019 | World Journal of Gastroenterology2019，25，20： | 6 |
| 11 | Development of a coupled supersonic inlet-fan Navier–Stokes simulation method显示文摘A coupled supersonic inlet-fan Navier–Stokes simulation method was developed by using COMSOL-CFD code. The flow turning, pressure rise and loss effects across blade rows of the fan and the inlet-fan interactions were taken into account as source terms of the governing equations without a blade geometry by a body force model. In this model, viscous effects in blade passages can also be calculated directly, which include the exchange of momentum between fluids and detailed viscous flow close to walls. NASA Rotor 37 compressor test rig was used to validate the ability of the body force model to estimate the real performance of blade rows. Calculated pressure ratio characteristics and the distribution of the total pressure, total temperature, and swirl angle in the span direction agreed well with experimental and numerical data. It is shown that the body force model is a promising approach for predicting the flow field of the turbomachinery. Then, coupled axisymmetric mixed compression supersonic inlet-fan simulations were conducted at Mach number 2.8 operating conditions. The analysis includes coupled steady-state performance, and effects of the fan on the inlet. The results indicate that the coupled simulation method is capable of simulating behavior of the supersonic inlet-fan system. | Qiushi LI Yongzhao LYU Tianyu PAN Da LI Ha'nan LU Yifang GONG | 2018 | Chinese Journal of Aeronautics2018，31，2： | 5 |
| 12 | DeST 3.0:A new-generation building performance simulation platform显示文摘Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in novel building technologies,the requirements of high-performance computation,and the demands for multi-objective models have brought new challenges for building energy modeling software and platforms.To meet the increasing simulation demands,DeST 3.0,a new-generation building performance simulation platform,was developed and released.The structure of DeST 3.0 incorporates four simulation engines,including building analysis and simulation(BAS)engine,HVAC system engine,combined plant simulation(CPS)engine,and energy system(ES)engine,connected by air loop and water loop balancing iterations.DeST 3.0 offers numerous new simulation features,such as advanced simulation modules for building envelopes,occupant behavior and energy systems,cross-platform and compatible simulation kernel,FMI/FMU-based co-simulation functionalities,and high-performance parallel simulation architecture.DeST 3.0 has been thoroughly evaluated and validated using code verification,inter-program comparison,and case-study calibration.DeST 3.0 has been applied in various aspects throughout the building lifecycle,supporting building design,operation,retrofit analysis,code appliance,technology adaptability evaluation as well as research and education.The new generation building simulation platform DeST 3.0 provides an efficient tool and comprehensive simulation platform for lifecycle building performance analysis and optimization. | Da Yan Xin Zhou Jingjing An Xuyuan Kang Fan Bu Youming Chen Yiqun Pan Yan Gao Qunli Zhang Hui Zhou Kuining Qiu Jing Liu Yan Liu Honglian Li Lei Zhang Hong Dong Lixin Sun Song Pan Xiang Zhou Zhe Tian Wenjie Zhang Ruhong Wu Hongsan Sun Yu Huang Xiaohong Su Yongwei Zhang Rui Shen Diankun Chen Guangyuan Wei Yixing Chen Jinqing Peng | 2022 | Building Simulation2022，15，11： | 5 |
| 13 | A correlation study of the expression of resistin and glycometabolism in muscle tissue after traumatic brain injury in rats显示文摘 | Jin Peng Zhu Lielie Zhang Jiasheng Xie Songling Pan Da Wen Hao Meng Weiyang Lin Luyang Chen Daqing | 2014 | Chinese Journal of Traumatology2014，17，3： | 5 |
| 14 | The First Outbreak of Omicron Subvariant BA.5.2—Beijing Municipality,China,July 4,2022显示文摘On July 4,2022,the first case of Omicron subvariant BA.5.2 in Beijing Municipality was discovered in Yanqing District.The case was a 49-yearold Chinese male who had arrived in Shanghai Municipality via international flight DL9927 from North Carolina,U.S.on June 15.He stayed in a hotel for the 14-day arrival quarantine and was discharged on June 30.He arrived in Beijing via domestic flight MU5103 on July 1 and was transferred point-to-point from the airport to his residence community in Yanqing District.On July 3,his sample was collected through community mass screening and reported positive in the next morning.The case had received 3 doses of Moderna’s mRNA vaccines in the U.S.,with the last shot on May 26,2022. | Zhaomin Feng Ying Shen Shuang Li Jia Li Shaohua Wang Zhenquan Zhang Yunkui Shen Fu Li Yang Pan Quanyi Wang Da Huo | 2022 | China CDC weekly2022，4，30： | 4 |
| 15 | PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death显示文摘5-Fluorouracil(5-FU)is known as a first-line chemotherapeutic agent against colorectal cancer(CRC),but drug resistance occurs frequently and significantly limits its clinical success.Our previous study showed that the protocadherin 17(PCDH17)gene was frequently methylated and functioned as a tumor suppressor in CRC.However,the relationship between PCDH17 and 5-FU resistance in CRC remains unclear.Here,we revealed that PCDH17 was more highly expressed in 5-FU-sensitive CRC tissues than in 5-FU-resistant CRC tissues,and high expression of PCDH17 was correlated with high BECN1 expression.Moreover,this expression profile contributed to superior prognosis and increased survival in CRC patients.Restoring PCDH17 expression augmented the 5-FU sensitivity of CRC in vitro and in vivo by promoting apoptosis and autophagic cell death.Furthermore,autophagy played a dominant role in PCDH17-induced cell death,as an autophagy inhibitor blocked cell death to a greater extent than the pancaspase inhibitor Z-VAD-FMK.PCDH17 inhibition by siRNA decreased the autophagy response and 5-FU sensitivity.Mechanistically,we showed that c-Jun NH2-terminal kinase(JNK)activation was a key determinant in PCDH17-induced autophagy.The compound SP600125,an inhibitor of JNK,suppressed autophagy and 5-FU-induced cell death in PCDH17-reexpressing CRC cells.Taken together,our findings suggest for the first time that PCDH17 increases the sensitivity of CRC to 5-FU treatment by inducing apoptosis and JNK-dependent autophagic cell death.PCDH17 may be a potential prognostic marker for predicting 5-FU sensitivity in CRC patients. | Shuiping Liu Haoming Lin Da Wang Qiang Li Hong Luo Guoxiong Li Xiaohui Chen Yongqiang Li Peng Chen Bingtao Zhai Wengang Wang Ruonan Zhang Bi Chen Mingming Zhang Xuemeng Han Qiujie Li Liuxi Chen Ying Liu Xiaying Chen Guohua Li Yu Xiang Ting Duan Jiao Feng Jianshu Lou Xingxing Huang Qin Zhang Ting Pan Lili Yan Ting Jin Wenzheng Zhang Lvjia Zhuo Yitian Sun Tian Xie Xinbing Sui | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 4 |
| 16 | Inverse relations between Helicobacter pylori infection and risk of esophageal precancerous lesions in drinkers and peanut consumption显示文摘BACKGROUND Helicobacter pylori(H. pylori) is a Gram-negative bacterium found in the upper digestive tract. Although H. pylori infection is an identified risk factor for gastric cancer, its role in esophageal squamous cell carcinoma(ESCC) remains a topic of much debate.AIM To evaluate the association between H. pylori infection and the risk of precancerous lesions of ESCC, and further explore the association between dietary factors and the risk of H. pylori infection.METHODS Two hundred patients with esophageal precancerous lesions(EPL) aged 63.01 ± 6.08 years and 200 healthy controls aged 62.85 ± 6.03 years were included in this case-control study. Epidemiological data and qualitative food frequency data were investigated. Enzyme-linked immunosorbent assay measuring serum immunoglobulin G antibodies was used to determine H. pylori seropositivity. An unconditional logistic regression model was used to assess the association between H. pylori infection and EPL risk dichotomized by gender, age, and the use of tobacco and alcohol, as well as the association between dietary factors and the risk of H. pylori infection.RESULTS A total of 47(23.5%) EPL cases and 58(29.0%) healthy controls had positive H. pylori infection. An inverse relation between H. pylori infection and the risk of EPL was found in the group of drinkers after adjustment for covariates [odds ratio(OR) = 0.32, 95% confidence interval(95%CI): 0.11-0.95]. Additionally, peanut intake was significantly associated with a decreased risk of H. pylori infection(OR = 0.39, 95%CI: 0.20-0.74).CONCLUSION Our study suggested that H. pylori infection may decrease the risk of EPL for drinkers in a rural adult Chinese population, and the consumption of peanut may reduce the risk of H. pylori infection. These findings should be framed as preliminary evidence, and further studies are required to address whether the mechanisms are related to the localization of lesions and alcohol consumption. | Da Pan Gui-Ju Sun Ming Su Xin Wang Qing-Yang Yan Guang Song Yuan-Yuan Wang Deng-Feng Xu Nian-Nian Wang Shao-Kang Wang | 2022 | World Journal of Gastrointestinal Oncology2022，14，9： | 3 |
| 17 | Performance Validation and Analysis for Multi-Method Fusion Based Image Quality Metrics in A New Image Database显示文摘Considering that there is no single full reference image quality assessment method that could give the best performance in all situations, some multi-method fusion metrics were proposed. Machine learning techniques are often involved in such multi-method fusion metrics so that its output would be more consistent with human visual perceptions. On the other hand, the robustness and generalization ability of these multi-method fusion metrics are questioned because of the scarce of images with mean opinion scores. In order to comprehensively validate whether or not the generalization ability of such multi-method fusion IQA metrics are satisfying, we construct a new image database which contains up to 60 reference images. The newly built image database is then used to test the generalization ability of different multi-method fusion IQA metrics. Cross database validation experiment indicates that in our new image database, the performances of all the multi-method fusion IQA metrics have no statistical significant different with some single-method IQA metrics such as FSIM and MAD. In the end, a thorough analysis is given to explain why the performance of multi-method fusion IQA framework drop significantly in cross database validation. | Xiaoyu Ma Xiuhua Jiang Da Pan | 2019 | China Communications2019，16，8： | 3 |
| 18 | Studies on the Structure of Kansuinine A from Euphorbia kansui显示文摘Kansuinine A is a macrocyclic jatrophane diterpene that was isolated from Euphorbia kansui. Further investigation of the structure was revealed that the benzoyl group located at C-8 and the position of C-3 was the present of an acetyl group by means of HMQC, HMBC spectra. | Qin PAN*, Zhi Da MIN Department of Natural Medicine Chemistry, China Pharmaceutical University, Nanjing 210009 | 2002 | Chinese Chemical Letters2002，13，12： | 2 |
| 19 | Syndrome of insulin resistance in the rat:Inducement by diet and amelioration with benfluorex显示文摘 | Storlien L H Oakes N D Pan DA | 1993 | Diabetes1993，42，： | 1 |
| 20 | New and emerging imaging techniques for mapping brain circuitry显示文摘 | Pan H Epstein J Silbersweig DA | | 0，，： | 1 |
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