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| 1 | Efficacy and safety of Shaoyang Xibi decoction in patients with knee osteoarthritis:a multi-center,single-blind,randomized controlled trial显示文摘PURPOSE: To observe the efficacy and safety of Shaoyang Xibi decoction(SYXBD) in patients with knee osteoarthritis(KOA), and to verify that the theory of 'Shaoyang dominating bone' in Traditional Chinese Medicine(TCM) can be applied to KOA treatment.METHODS: Participants were randomly allocated to two groups: SYXBD(treatment group, n = 66)and Meloxicam(control group, n = 66). Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) and 36-Item Short Form Health Survey(SF-36) were used to assess efficacy before the treatment and 8 weeks after the treatment.RESULTS: Baseline data before the treatment between the two groups were similar. The WOMAC scores significantly decreased and the SF-36 scores significantly increased after 8-week treatment in both groups compared with before the treatment(P < 0.05). SYXBD significantly decreased pain scores(P < 0.001), physical function scores(P <0.001) and the total scores(P < 0.001) in WOMAC compared to Meloxicam. SYXBD significantly improved physical function(P = 0.021), bodily pain(P = 0.002) and general health(P = 0.014), with no significant difference in role emotional(P = 0.053),role physical(P = 0.517), vitality(P = 0.241), social function(P = 0.712) and mental health(P = 0.800)in SF-36 compared to Meloxicam. No adverse events were reported in the treatment group while13 adverse events happened in the control group during the study.CONCLUSION: SYXBD, prepared based on the theory of 'Shaoyang dominating bone', has a better curative efficay and safety in patients with KOA compared with Meloxicam. The TCM theory of 'Shaoyang dominating bone' may be useful in KOA treatment. | Si Yuhao Ma Yong Guo Yang Pan Yalan Zheng Suyang Xu Guihua Da Weiwei Xu Lili | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 11 |
| 2 | Mizoribine versus mycophenolate mofetil or intravenous cyclophosphamide for induction treatment of active lupus nephritis显示文摘 | Feng Xuebing Gu Fei Chen Weiwei Liu Yan Wei Hua Liu Lin Yin Songlou Da Zhanyun Sun Lingyun | 2014 | Chinese Medical Journal2014，，21： | 5 |
| 3 | Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice显示文摘 | Yi-Xin Wang Valdeci da Cunha Baby Martin-McNulty Jon Vincelette Weiwei Li David F. Choy Meredith Halks-Miller Mithra Mahmoudi Miriam Schroeder Anthony Johns David R. Light William P. Dole | 2005 | European Journal of Pharmacology2005，，2： | 2 |
| 4 | Room temperature ozone sensing properties of p-type CuCrO 2 nanocrystals显示文摘 | Shu Zhou Xiaodong Fang Zanhong Deng Da Li Weiwei Dong Ruhua Tao Gang Meng Tao Wang | 2009 | Sensors & Actuators: B Chemical2009，，1： | 1 |
| 5 | Hydrothermal synthesis and characterization of CuCrO 2 laminar nanocrystals显示文摘 | Shu Zhou Xiaodong Fang Zanhong Deng Da Li Weiwei Dong Ruhua Tao Gang Meng Tao Wang Xuebin Zhu | 2008 | Journal of Crystal Growth2008，，24： | 1 |
| 6 | Metal-semi- conductor transition in Nb-doped ZnO thin films pre pared by pulsed laser deposition 显示文摘 | Shao Jingzhen Dong Weiwei Li Da | 2010 | Thin solid films2010，518，： | 1 |
| 7 | Typhoon Case Comparison Analysis Between Heterogeneous Many-Core and Homogenous Multicore Supercomputing Platforms显示文摘In this paper,a typical experiment is carried out based on a high-resolution air-sea coupled model,namely,the coupled ocean-atmosphere-wave-sediment transport(COAWST)model,on both heterogeneous many-core(SW)and homogenous multicore(Intel)supercomputing platforms.We construct a hindcast of Typhoon Lekima on both the SW and Intel platforms,compare the simulation results between these two platforms and compare the key elements of the atmospheric and ocean modules to reanalysis data.The comparative experiment in this typhoon case indicates that the domestic many-core computing platform and general cluster yield almost no differences in the simulated typhoon path and intensity,and the differences in surface pressure(PSFC)in the WRF model and sea surface temperature(SST)in the short-range forecast are very small,whereas a major difference can be identified at high latitudes after the first 10 days.Further heat budget analysis verifies that the differences in SST after 10 days are mainly caused by shortwave radiation variations,as influenced by subsequently generated typhoons in the system.These typhoons generated in the hindcast after the first 10 days attain obviously different trajectories between the two platforms. | LIU Xin YU Xiaolin ZHAO Haoran HAN Qiqi ZHANG Jie WANG Chengzhi MA Weiwei XU Da | 2023 | Journal of Ocean University of China2023，22，2： | 0 |
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