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| 1 | Function and regulation of self-reactive marginal zone B cells in autoimmune arthritis显示文摘Polyreactive 天生类型的 B 房间说明在圆周表示自我反应的许多 B 房间。这些 B 房间的不适当的规定可以是位于自体免疫的疾病下面的一个重要因素。这里,我们在导致骨胶原的关节炎(中央情报局) 的开发探索了自我反应的天生的 B 房间的影响,风湿性关节炎的一个鼠标模型。我们显示出那个脾的边缘的地区(MZ ) ,然而并非 B-1 B 房间在 naı 展出自发的 IgM 反应到自体同源的骨胶原 II; ¨ ve 老鼠。在有在完全的 Freund’ 的 heterologous 骨胶原 II 的免疫之上;骨胶原反应的 MZ B 房间很快扩展了的 s 助手,当 B-1 B 房间显示出谦虚反骨胶原回答时。MZ B 房间被像使用费的受体(TLR ) 容易激活 4 并且在 vitro,导致的增长和 cytokine 分泌物的 9-ligands,暗示 B 房间受体和 TLR 的那个双约会可以把有免疫力的反应提升到自我抗原。而且,告知骨胶原的 MZ B 房间显示出在 vivo 在 IgG 反骨胶原抗体的 vitro 和正式就职由血缘的 T 房间增长思考了的重要介绍抗原的能力。在 1 和 2 表明了的补充受体是缺乏的 MZ B 房间增加了增长和 cytokine 生产,当时 Fcγ房间的受体 IIb 缺乏导致增加的 cytokine 生产和抗原表示。在结论,我们的数据在中央情报局作为自体免疫的反应的开始者加亮自我反应的 MZ B 房间,在补充和 Fc 受体在在房间控制自我反应是相关的的地方。 | Anna-Karin E Palm Heike C Friedrich Anja Mezger Maya Salomonsson Linda K Myers Sandra Kleinau | 2015 | Cellular & Molecular Immunology2015，12，4： | 3 |
| 2 | Towards a unified paradigm for sequence‐based identification of fungi显示文摘 | Urmas K?ljalg R. Henrik Nilsson Kessy Abarenkov Leho Tedersoo Andy F. S. Taylor Mohammad Bahram Scott T. Bates Thomas D. Bruns Johan Bengtsson‐Palme Tony M. Callaghan Brian Douglas Tiia Drenkhan Ursula Eberhardt Margarita Due?as Tine Grebenc Gareth W. Gri | 2013 | Mol Ecol2013，，21： | 2 |
| 3 | Irradiation Induces a Biphasic Expression of Pro-Inflammatory Cytokines in the Lung显示文摘 | Claudia E. Rübe MD Falk Wilfert Jan Palm Jochem K?nig Susanne Burdak-Rothkamm Li Liu Andreas Schuck Normann Willich Christian Rübe | 2004 | Strahlentherapie und Onkologie2004，，7： | 2 |
| 4 | A mieroarray search for genes predominantly expressed in human omental adipocytes:adipose tissue as a major production site of serum amyloid A显示文摘 | Sjoholm K Palming J Olofsson LE | 2005 | Clin Endocrinol Metab2005，90，4： | 1 |
| 5 | Caco-2 monolayers in experimental and theoretical predictions of drug transport 显示文摘 | Arturrsson S Palm K Luthman K | 2001 | Adv Drug Deliv Rev2001，46，13： | 1 |
| 6 | The auxin signal for protoplast swelling is perceived by extracellular ABP1 显示文摘 | STEFFENS B FECKLER PALME K | 2001 | Plant J2001，27，6： | 1 |
| 7 | Matrix-Metallo-Proteinases and their tissue inhibitors in radiation-induced lung injury显示文摘 | Yang K Palm J K?nig J | | 0，，10： | 1 |
| 8 | Bundle-forming pili and EspA are involved in bioflm formation by en- teropathogenic Escherichia coli 显示文摘 | Moreira C Palme K Whitele M | 2006 | J Bacteriol2006，188，11： | 1 |
| 9 | Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in vitro and human jejunum in vivo显示文摘 | Lennernas H Palm K Fagerholm U | 1996 | Int J Pharm1996，127，1： | 1 |
| 10 | The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta blockers显示文摘 | PALM D LANG K NIGGERMANN B | | 0，，05： | 1 |
| 11 | Enhanced proliferation and differentiation of rat hepatocytes cultured with bone marrow stromal cells显示文摘 | Mizuguchi T Hui T Palm K | 2001 | Cell Physiol2001，189，1： | 1 |
| 12 | A new measurementfor posterior tilt predicts reoperation in undisplaeed femoral neckfractures: 113 consecutive patients treated by internal fixation andfollowed for 1 year 显示文摘 | Palm H Gosvig K Krasheninnikoff M | 2009 | Acta Orthop2009，80，3： | 1 |
| 13 | Pharmacokinetics of levetiracetam during pregnancy, delivery, in the neonatal period, and lactation显示文摘 | Tomson T Palm R K/ill6n K | 2007 | Epilepsia2007，48，6： | 1 |
| 14 | Flow cytometric assessment of lymphocyte subsets, lymphoid progenitors, and hematopoietic stem cells in ailogeneic stem cell grafts显示文摘 | Theilgaard-Monch K Raaschou-Jensen K Palm H | 2001 | Bone Marrow Transplant2001，28，11： | 1 |
| 15 | Rapid accretion and early core formation on asteroids and the terrestrial planets from Hf-W chronometry 显示文摘 | Kleine T Munker C Mezger K Palme H | 2002 | Nature2002，418，6901： | 1 |
| 16 | The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by b-blockers显示文摘 | Palm D Lang K Niggemann B | | 0，，11： | 1 |
| 17 | Review of root dynamics in forest ecosystems ground by climate, climatic forest type and species 显示文摘 | Vogt K A Vogt D J Palm iotto P A | 1996 | Plant and Soil1996，187，： | 1 |
| 18 | Compositional constraints on the continental lithospheric mantle from trace ele- ments in spinel peridotite xenoliths 显示文摘 | Jochum K P McDonough W F Palme H | 1989 | Nature1989，340，： | 1 |
| 19 | Etomidate-lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine显示文摘 | Nyman Y Von Hofsten K Palm C | 2006 | Br J Anaesth2006，97，： | 1 |
| 20 | Etomidate-Lipuro is associated with considerably less injection pain in children compared with propofol with added lidocaine显示文摘 | Nyman Y Von Hofsten K Palm C | 2006 | Br J Anaesth2006，97，4： | 1 |
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