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| 1 | 小关节不对称—青少年腰椎间盘突出症的放射学特征显示文摘目的 :成人与青少年腰椎间盘突出症中小关节不对称性的比较。方法 :研究组包括青少年组 2 5名患者 ,2 9个椎间盘和成人组 3 3名患者 ,5 0个椎间盘。使用CT测量每个小关节形态、小关节角、力矩臂角和长度。小关节不对称的诊断标准为 :双侧小关节的形态不同或双侧小关节角相差 10°以上。并比较了两组间小关节不对称的发生率及其与椎间盘突出的位置、类型以及椎间盘退变之间的关系。结果 :青少年组 (12个间盘 ,占 41% )小关节不对称的发生率明显高于成人组 (4个间盘 ,占 8% ) (P <0 .0 1)。小关节不对称与椎间盘突出的位置、类型以及椎间盘退变之间无统计学差异。结论 :小关节不对称性是青少年腰椎间盘突出症的一个放射学特点。 | 刘洪 Hirokazu Ishihara Ryusuke Osada | 2003 | 中国矫形外科杂志2003，11，24： | 7 |
| 2 | Factors associated with incomplete colonoscopy at a Japanese academic hospital显示文摘AIM:To evaluate significant risk factors for incomplete colonoscopy at a Japanese academic hospital.METHODS:A total of 11812 consecutive Japanese people were identified who underwent a colonoscopy at an academic hospital.A multiple logistic regression model was used to evaluate retrospectively the significant risk factors for incomplete colonoscopy.RESULTS:The cecal intubation rate was 95.0%.By univariate analysis,age,female sex,poor bowel cleansing,and a history of abdominal or pelvic surgery were significant risk factors for incomplete colonoscopy(P<0.001).Moreover,age-and sex-adjusted analysis showed that significant risk factors for incomplete colonoscopy were female sex(OR=1.38,95%CI:1.17-1.64,P=0.0002),age≥60 years old(OR=1.44,95%CI:1.22-1.71,P<0.0001),a history of prior abdominal or pelvic surgery(OR=1.55,95%CI:1.28-1.86,P<0.0001),poor bowel cleansing(OR=4.64,95%CI:3.69-5.84,P<0.0001),and inflammatory bowel disease(IBD)(OR=1.48,95%CI:1.13-1.95,P=0.0048).In Japanese men,by age-adjusted analysis,IBD(OR=1.69,95%CI:1.18-2.43,P=0.005)was an independent risk factor for incomplete colonoscopy.CONCLUSION:Several characteristics in the Japanese population were identified that could predict technical difficulty with colonoscopy. | Shigeo Koido Toshifumi Ohkusa Kosaburo Nakae Tetsuji Yokoyama Tomoyoshi Shibuya Naoto Sakamoto Kan Uchiyama Hiroshi Arakawa Taro Osada Akihito Nagahara Sumio Watanabe Hisao Tajiri | 2014 | World Journal of Gastroenterology2014，20，22： | 6 |
| 3 | Autofluorescence imaging endoscopy for identifi cation and assessment of inflammatory ulcerative colitis显示文摘AIM:To validate the clinical relevance of autofluores-cence imaging(AFI)endoscopy for the assessment of inflammatory ulcerative colitis(UC).METHODS:A total of 572 endoscopic images were se-lected from 42 UC patients:286 taken with white light imaging(WLI)and 286 with AFI from the same sites.WLI images were assessed for overall mucosal inflammation according to Mayo endoscopic subscore(MES),and for seven characteristic endoscopic features.Likewise,AFI photographs were scored according to relative abundance of red,green and blue color com-ponents within each image based on an RGB additive color model.WLI and AFI endoscopic scores from the same sites were compared.Histological evaluation of biopsies was according to the Riley Index.RESULTS:Relative to red(r=0.52,P<0.01)or blue(r=0.56,P<0.01)color component,the green color component of AFI(r=-0.62,P<0.01)corresponded more closely with mucosal inflammation sites.There were signif icant differences in green color components between MES-0(0.396±0.043)and MES-1(0.340± 0.035)(P<0.01),and between MES-1 and ≥ MES-2(0.318±0.037)(P<0.01).The WLI scores for 'vascu-lar patterns'(r=-0.65,P<0.01),'edema'(r=-0.62,P<0.01),histology scores for 'polymorphonuclear cells in the lamina propria'(r=-0.51,P<0.01)and 'crypt architectural irregularities'(r=-0.51,P<0.01)showed correlation with the green color component of AFI.There were significant differences in green color components between limited(0.399± 0.042)and extensive(0.375±0.044)(P=0.014)polymorpho-nuclear cell inf iltration within MES-0.As the severity of the mucosal inflammation increased,the green color component of AFI decreased.The AFI green color com-ponent was well correlated with the characteristic en-doscopic and histological inflammatory features of UC.CONCLUSION:AFI has application in detecting inflammatory lesions,including microscopic activity in the co-lonic mucosa of UC patients,based on the green color component of images. | Taro Osada Atsushi Arakawa Naoto Sakamoto Hiroya Ueyama Tomoyoshi Shibuya Tatsuo Ogihara Takashi Yao Sumio Watanabe | 2011 | World Journal of Gastroenterology2011，17，46： | 5 |
| 4 | Analysis on Temperature Distributions in Single Cell of Polymer Electrolyte Fuel Cell When Operated in High Temperature Range显示文摘 | Akira Nishimura Kotaro Osada Takuro Tsunoda Masato Yoshimura Masafumi Hirota Eric Hu | 2016 | Journal of Energy and Power Engineering2016，10，8： | 5 |
| 5 | Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer显示文摘AIM To evaluate the clinical outcome of endoscopic submucosal dissection using the Clutch Cutter(ESDCC) in older patients. METHODS We reviewed 232 consecutive patients with early gastric cancer who underwent ESDCC between June 2010 and February 2014 at Aso Iizuka Hospital. We divided patients into two groups according to age: Older patients(> 80 years, n = 64) and non-older patients(≤ 80 years, n = 168). We retrospectively compared the prevalence rates of pre-existing comorbidities, anticoagulant therapy, en bloc resection, mean duration of hospitalization, incidence of ESDCC-related complications, change in performance status(PS) before and after ESDCC, and financial cost of admission. RESULTS The older group comprised 64 patients with a mean age of 84.1 years, and the non-older group comprised 168 patients with a mean age of 69.5 years. Older patients had significantly more pre-existing comorbidities than did non-older patients, specifically heart disease(P < 0.05). The en bloc resection rate in non-older patients was significantly higher than that in older patients(100% vs 95.3%, P = 0.02). There were no significant differences between the older and non-older groups in the incidence of ESDCC-related complications(i.e., postoperative bleeding and perforation) and the post-ESDCC change in PS. There were also no significant differences between the older and non-older groups in the mean duration of hospitalization(11.4 and 10.7 d, respectively) and financial cost of admission(657040 JPY and 574890 JPY, respectively).CONCLUSION ESDCC has a good clinical outcome in older patients. | Yoshihiro Otsuka Kazuya Akahoshi Kayoko Yasunaga Masaru Kubokawa Junya Gibo Shigeki Osada Kayo Tokumaru Kazuaki Miyamoto Takao Sato Yuki Shiratsuchi Masafumi Oya Hidenobu Koga Eikichi Ihara Kazuhiko Nakamura | 2017 | World Journal of Gastrointestinal Oncology2017，9，10： | 4 |
| 6 | 智能凝胶显示文摘长链分子的软聚体随着外界刺激可以收缩或膨胀,由此形成一种新型机械的基础。 | Yoshihito Osada Simon B.Ross-Murphy 李继红 | 1994 | 中国科学基金1994，8，1： | 4 |
| 7 | Seasonal variations in the onset of ulcerative colitis in Japan显示文摘AIM:To investigate seasonal variations in the onset and relapse of ulcerative colitis(UC)in Japanese patients.METHODS:Between 1994 and 2006,198 Japanese patients diagnosed with UC according to conventional criteria in an academic hospital were enrolled for onset evaluation.Among 265 Japanese patients with UC who were observed for more than 12 mo,165 patients relapsed(239 times)and were enrolled for relapse evaluation.The patients’symptoms were recorded each month for 12 consecutive years.RESULTS:There was monthly seasonality in symptom onset during October and March for UC.The onset of symptoms in UC patients frequently occurred during the winter.Variation in UC onset was observed according to both month(P=0.015)and season(P=0.048).Relapse commonly occurred in October,and variations in relapse were not significant either in month(P=0.52)or season(P=0.12).Upper respiratory inflammation was the main factor responsible for relapse.CONCLUSION:Our results suggest that environmental factors associated with winter and spring seasonality may be responsible for triggering the clinical onset of UC in Japan. | Shigeo Koido Toshifumi Ohkusa Hiroaki Saito Tetsuji Yokoyama Tomoyoshi Shibuya Naoto Sakamoto Kan Uchiyama Hiroshi Arakawa Taro Osada Akihito Nagahara Sumio Watanabe Hisao Tajiri | 2013 | World Journal of Gastroenterology2013，19，47： | 3 |
| 8 | Characteristic pathological findings and effects of ecabet sodium in rat reflux esophagitis显示文摘AIM:To explore the pathological flndings in the entire esophagus in rats with reflux esophagitis, and the effects of ecabet sodium(ES).METHODS:A rat model of chronic acid reflux esophagitis was used.In the treatment group, ES was administered after surgery(n = 16).No drug was administered postoperatively to the esophagitis group(n = 9).Shamoperated rats were used as a control group(n = 5).Rats were sacriflced on day 7 after the operation.The epithelial thickness and leukocyte inflltration were examined in the upper, middle and lower areas of the esophagus.The survival rate, incidence of esophageal ulcer, and mean surface area and number of esophageal ulcers were determined in the esophagitis and ES groups.Esophageal histology was assessed in all three groups.RESULTS:Leukocyte infiltration in the esophagitis group was 26.3 ± 22.0 in the middle esophagus and 8.2 ± 4.9 in the upper esophagus, which was signiflcantly greater than that in the controls(1.3 ± 1.1 and 1.4 ± 1.0, respectively)(P < 0.05).The thickness of the epithelium in the esophagitis group was 210.8 ± 47.7 μm in the lower esophagus and 204.2 ± 60.1 μm in the middle esophagus, which was significantlygreater than that in the controls(26.0 ± 5.5 and 21.0 ± 6.5 μm, respectively)(P < 0.05).The mean number of ulcers per animal in the ES group in the entire esophagus was 5.4 ± 2.5, which was signiflcantly less than that in the esophagitis group(9.0 ± 3.5)(P < 0.05).The epithelial thickness in the ES group was 97.5 ± 32.2 μm in the lower esophagus, which was decreased compared with that in the esophagitis group(210.8 ± 47.7 μm)(P < 0.05).CONCLUSION:Mucosal inflammation extended to the upper esophagus close to the hypopharynx.Our study suggested that ES may have a useful defensive role in reflux esophagitis. | Daisuke Asaoka Akihito Nagahara Masako Oguro Yuko Izumi Akihiko Kurosawa Taro Osada Masato Kawabe Mariko Hojo Michiro Otaka Sumio Watanabe | 2009 | World Journal of Gastroenterology2009，15，28： | 2 |
| 9 | Gastrointestinal stromal tumor of the stomach with a giant abscess penetrating the gastric lumen显示文摘Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. In large GISTs, cystic degeneration, necrosis and focal hemorrhage that occur inside the tumor can result in gastrointestinal bleeding. We describe a case of a 74-year old male with GIST of the stomach accompanied with a giant abscess that penetrated the gastric lumen. The patient experienced undiagnosed fever for two months prior to hospitalization. Gastrointestinal endoscopy, X-ray series and computed tomography of the patient’s abdomen revealed a gastric submucosal tumor in the fornix, with a fistula to the gastric lumen that was inundated with a great deal of pus. The mass was diagnosed as a GIST from biopsy specimens. The patient was treated by endoscopic drainage of the abscess and intravenous administration of antibiotics. Eventually, a partial gastrectomy was performed. He was also administered Imanitib mesylate as adjuvant therapy. He was followed up for 2 years and no metastasis or recurrence was recognized at the follow- up examinations. This is the first report of a patient with clearly diagnosed GIST with endoscopic evidence of an abscess penetrating into the gastric lumen. | Taro Osada Akihito Nagahara Tomohiro Kodani Akihiro Namihisa Masato Kawabe Takashi Yoshizawa Toshifumi Ohkusa Sumio Watanabe | 2007 | World Journal of Gastroenterology2007，13，16： | 2 |
| 10 | Asian international grid connection and potentiality of DC superconducting power transmission显示文摘In 2011, a large scale earthquake and tsunami hit the northeastern coast of Japan, and nuclear plants were damaged to a large extent. Before the Tsunami, 54 nuclear plants were operated, however presently, only three nuclear plants are in operation. Therefore, Japan is suffering from high price of electricity and low supply reliability. In generation mix, nuclear plants generate only one percent and 87 percent of electricity is generated by fossil energy. This is not preferable for Japan from the viewpoints of energy security and stable electricity supply. Therefore, it is mandatory to increase sustainable energy and to decrease consumption of fossil fuel. International grid connection and the Global Energy Interconnection will be one of countermeasures against these problems existing in Japan. In this paper, international grid connection initiatives proposed in Asia are described and features and issues of electric power grids in Japan are discussed to implement the international grid connection. As the key technology for implementing the international grid connection, the present status of DC superconducting power transmission lines and power converters for long-distance power transmission lines are presented. In conclusion, conditions and legal frameworks for realizing the international grid connection are described. | Satarou Yamaguchi Takashi Iitsuka Masashi Osada Ryuichi Yokoyama | 2018 | Global Energy Interconnection2018，1，1： | 2 |
| 11 | Patterns and quantities of NH 3 , N 2 O and CH 4 emissions during swine manure composting without forced aeration––effect of compost pile scale显示文摘 | Yasuyuki Fukumoto Takashi Osada Dai Hanajima Kiyonori Haga | 2003 | Bioresource Technology2003，，2： | 2 |
| 12 | Methane, Nitrous Oxide and Ammonia generation in full-scale swine wastewater purification facilities显示文摘 | Takashi Osada Makoto Shiraishi Teruaki Hasegawa Hirofumi Kawahara | 2017 | Frontiers of Environmental Science & Engineering2017，11，3： | 2 |
| 13 | SUPER TOUGH GELS WITH A DOUBLE NETWORK STRUCTURE显示文摘Living tissues work with fantastic functions in soft and wet gel-like state.Thus,hydrogels have attracted much attention as excellent soft and wet materials,suitable tot making artificial organs for medical treatments.However, conventional hydrogels are mechanically too weak for practical uses.We have created double network (DN) hydrogels with extremely high mechanical strength in order to overcome this problem.DN gels are interpenetrating network (IPN) hydrogels consisting of rigid polyelectrolyte and s... | Tasuku Nakajima Takayuki Kurokawa Hidemitsu Furukawa Yoshimi Tanaka Yoshihito Osada 龚剑萍 | 2009 | Chinese Journal of Polymer Science2009，27，1： | 2 |
| 14 | Shape distributions显示文摘 | Robert Osada Thomas Funkhouser Bernard Chazelle David Dobkin | 2002 | ACM Transactions on Graphics (TOG)2002，，4： | 2 |
| 15 | Obstructive jaundice caused by secondary pancreatic tumor from malignant solitary fibrous tumor of pleura:A case report显示文摘对胸膜的恶意的独居的含纤维的肿瘤的手术后的双边的多重肺转移的全身的化疗上的一个 77 岁的人受不了瘙痒和黄疸。血检查显示出肝胆管酶的提高的层次。腹的计算断层摄影术在胰腺的头与外部改进显示出一个肿瘤,与 intra 肝、额外肝的胆汁管的膨胀伴随了。他作为把妨碍的黄疸被一个胰腺的头肿瘤引起了被诊断。胰腺的头肿瘤大概作为胸膜的恶意的独居的含纤维的肿瘤的转移被诊断,因为腹的 CT 上的胰腺的头肿瘤上的调查结果类似于胸膜的恶意的独居的含纤维的肿瘤的主要的肺损害上的那些。胰腺的肿瘤在胆总管的劣等的部分在金属性的斯滕特氏印模膏的培植以后很快成长了。病人死于肺的癌性淋巴管炎。尸体揭示了从胰腺的头传播了到肝的核的一个肿瘤。用显微镜,和骨胶原免职展出原子 atypicality 或分割的塑造锭子的房间被观察。Immunohistochemically 胰腺的头肿瘤房间为 alpha 光滑的肌肉肌动朊(alpha-SMA ) 或 CD117 染色是否定的,但是为 vimentin, CD34 和 CD99 积极。这些调查结果与胸膜的恶意的独居的含纤维的肿瘤上的那些一致。我们报导一个第二等的胰腺的肿瘤从胸膜的恶意的独居的含纤维的肿瘤引起的妨碍的黄疸的第一个案例。 | Norie Yamada Chiaki Okuse Masahito Nomoto Mayu Orita Yoshiki Katakura Toshiya Ishii Takuo Shinmyo Hiroaki Osada Ichiro Maeda Hiroshi Yotsuyanagi Michihiro Suzuki Fumio Itoh | 2006 | World Journal of Gastroenterology2006，12，30： | 2 |
| 16 | Phase I clinical trial of peptide vaccination with URLC10 and VEGFR1epitope peptides in patients with advanced gastric cancer显示文摘 | Yoshie Higashihara Junko Kato Akihito Nagahara Kentaro Izumi Masae Konishi Tomohiro Kodani Nobuko Serizawa Taro Osada Sumio Watanabe | 2014 | International Journal of Oncology2014，，： | 2 |
| 17 | Hepatocellular carcinoma with obstructive jaundice successfully treated with a self-expandable metallic stent显示文摘 | Morihiro Okazaki Akifumi Mizuta Noboru Hamada Nozomu Kawamura Kazushi Nakao Takeshi Kikuchi Takahisa Osada | 1998 | Journal of Gastroenterology1998，，6： | 2 |
| 18 | SYNTHETIC HYDROGELS AS SCAFFOLDS FOR MANIPULATING ENDOTHELIUM CELL BEHAVIORS显示文摘合成 hydrogels 能被用作赞成 endothelial 房间(EC ) 的脚手架不仅增长而且操作 EC 的行为和功能。在这份评论报纸,化学结构的效果,幼仔模量(E)和希腊语的第六个字母潜力()静态的房间行为上的合成 hydrogel 脚手架,包括房间形态学,增长,细胞骨架结构和焦点的粘附,并且在动态房间行为上包括迁居速度和形态学摆动,象在象反血小板粘附那样的 EC 功能上一样,被报导。否定地收了 hydrogels,被发现那, poly (2-acrylamido-2-methylpropanesulfonic 钠)(PNaAMPS ) 并且 poly (钠 p 苯乙烯磺酸盐)(PNaSS ) ,能直接支持房间增长,没有由在包含浆液的媒介的环境的任何房间粘合剂蛋白质或肽的表面修正的需要。另外,幼仔模量(E)和希腊语的第六个字母潜力() hydrogel 脚手架,份量上被共聚物 hydrogels 调节, poly ( NaAMPS-co-DMAAm )并且 poly ( NaSS-co-DMAAm ),在哪个二种否定地控告的单体 NaAMPS 和 NaSS 与中立单体被异分子聚合, N , N-dimethylacrylamide ( DMAAm )。操作 EC 形态学,增长,和活动性的 hydrogels 的批评希腊语的第六个字母潜力是批评 = ,这被发现 ? 20.83 mV 和批评 =? 14.0 mV 为 poly (NaAMPS-co-DMAAm ) 并且 poly (NaSS-co-DMAAm ) 分别地。上述提及的 EC 行为很好与 fibronectin 的吸附相关,一种房间粘合剂蛋白质,在 hydrogel 表面上。而且,粘住在 hydrogel 脚手架上有教养的 EC 单层上的血小板显然随 hydrogels 的幼仔模量(E) 的增加减少,特别 E > 60 kPa。Glycocalyx 试金和 EC 的基因表示证明反血小板粘附很好与 EC 特定的 glycocalyx 相关。上述调查建议理解在合成 hydrogels 和房间回答的药品化学药品性质之间的关系是必要的为织物工程设计最佳的软、湿的脚手架。 | 陈咏梅 Yoshihito Osada | 2011 | Chinese Journal of Polymer Science2011，29，1： | 2 |
| 19 | Performance analysis of an oil-injected screw compressor and its application 显示文摘 | Fujiwara M Osada Y | 1995 | International Journal of Refrigeration1995，18，4： | 2 |
| 20 | Patterns and quantities of NH 3 , N 2 O and CH 4 emissions during swine manure composting without forced aeration––effect of compost pile scale显示文摘 | Yasuyuki Fukumoto Takashi Osada Dai Hanajima Kiyonori Haga | 2003 | Bioresource Technology2003，，2： | 2 |
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