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| 1 | High-resolution multimodal flexible coherent Raman endoscope显示文摘Coherent Raman scattering microscopy is a fast,label-free,and chemically specific imaging technique that shows high potential for future in vivo optical histology.However,the imaging depth in tissues is limited to the sub-millimeter range because of absorption and scattering.Realization of coherent Raman imaging using a fiber endoscope system is a crucial step towards imaging deep inside living tissues and providing information that is inaccessible with current microscopy tools.Until now,the development of coherent Raman endoscopy has been hampered by several issues,mainly related to the fiber delivery of the excitation pulses and signal collection.Here,we present a flexible,compact,coherent Raman,and multimodal nonlinear endoscope(4.2mm outer diameter,71mm rigid length)based on a resonantly scanned hollow-core Kagomé-lattice double-clad fiber.The fiber design enables distortion-less,background-free delivery of femtosecond excitation pulses and back-collection of nonlinear signals through the same fiber.Sub-micrometer spatial resolution over a large field of view is obtained by combination of a miniature objective lens with a silica microsphere lens inserted into the fiber core.We demonstrate high-resolution,high-contrast coherent anti-Stokes Raman scattering,and second harmonic generation endoscopic imaging of biological tissues over a field of view of 320μm at a rate of 0.8 frames per second.These results pave the way for intraoperative label-free imaging applied to real-time histopathology diagnosis and surgery guidance. | Alberto Lombardini Vasyl Mytskaniuk Siddharth Sivankutty Esben Ravn Andresen Xueqin Chen Jérôme Wenger Marc Fabert Nicolas Joly Frédéric Louradour Alexandre Kudlinski Hervé Rigneault | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 2 | Transcatheter Arterial Embolization of Splenic Artery Aneurysms and Pseudoaneurysms: Short- and Long-Term Results显示文摘 | Romaric Loffroy Boris Guiu Jean-Pierre Cercueil C?me Lepage Nicolas Cheynel Eric Steinmetz Frédéric Ricolfi Denis Krausé | 2008 | Annals of Vascular Surgery2008，，5： | 2 |
| 3 | Singular value decomposition of quaternion matrices: a new tool for vector-sensor signal processing显示文摘 | Nicolas Le Bihan Jér?me Mars | 2004 | Signal Processing2004，，7： | 2 |
| 4 | MicroRNA-21 Is Induced Early in Pancreatic Ductal Adenocarcinoma Precursor Lesions显示文摘 | du Rieu Ma?l Chalret Torrisani Jér?me Selves Janick Al Saati Talal Souque Anny Dufresne Marlène Tsongalis Gregory J Suriawinata Arief A Carrére Nicolas Buscail Louis Cordelier Pierre | 2010 | Clinical Chemistry2010，，： | 1 |
| 5 | Effects of short periods of drought and high temperature on grain growth and starch accumulation of two malting barley cultivars显示文摘 | Savin R Nicolas ME | 1996 | Functional Plant Biology1996，23，2： | 1 |
| 6 | Sodium/glucose eotransporter 2 inhibitors and prevention of diabetic nephropathy: targeting the renal tubule in diabetes显示文摘 | De Nicola L Gabbai FB Liberti ME | 2014 | Am J Kidney Dis2014，64，1： | 1 |
| 7 | Transferrin receptorl mRNA is downregulated in placenta of hepcidin transgenic embryos显示文摘 | Marton ME Nicolas G Hetet G | 2004 | FEBS Letters2004，574，13： | 1 |
| 8 | Dermatitis herpetiformis显示文摘 | Nicolas ME Krause PK Gibson LE | 2003 | International Journal of Dermatology2003，42，8： | 1 |
| 9 | Posterior dental size reduction in hominids : the Atapuerca evidence 显示文摘 | Bermudez de Castro JM Nicolas ME | 1995 | Am J Phys Anthropol1995，96，： | 1 |
| 10 | Video-assisted mediastinoscopy: experience from 240 consecutive cases显示文摘 | Nicolas Venissac Marco Alifano Jèr?me Mouroux | 2003 | The Annals of Thoracic Surgery2003，，1： | 1 |
| 11 | Wheat cultivars vary widely in their responses of grain-yield and quality to short periods of post anthesis heat-stress 显示文摘 | Stone P J Nicolas ME | 1994 | Australian Journal of Plant Physiology1994，21，： | 1 |
| 12 | The effect of duration of heat stress during grain filling on two wheat varieties differing in heat tolerance: grain growth and fractional protein accumulation 显示文摘 | Stone P J Nicolas ME | 1998 | Australian Journal of Plant Physiology1998，25，： | 1 |
| 13 | Serotonin transporter transgenic (SERT cre ) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs)显示文摘 | Nicolas Narboux-Nême Luigi Michele Pavone Luigi Avallone Xiaoxi Zhuang Patricia Gaspar | 2008 | Neuropharmacology2008，，6： | 1 |
| 14 | Human bone marrow stromal cells suppress T - lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli 显示文摘 | Di Nicola M Carlo- stella C Magni Me | 2002 | Blood2002，99，10： | 1 |
| 15 | Rituximab in refractory and non‐refractory myasthenia: A retrospective multicenter study显示文摘 | Nicolas Collongues Olivier Casez Arnaud Lacour Christine Tranchant Patrick Vermersch Jér?me de Seze Christine Lebrun | 2012 | Muscle Nerve2012，，5： | 1 |
| 16 | Sodium/glucose cotransporter 2 inhibitors and prevention of diabetic nephropathy:targeting the renal tubule in diabetes显示文摘 | De Nicola L Gabbai FB Liberti ME | 2014 | Am J Kidney Dis2014，64，1： | 1 |
| 17 | Lipoxins stmmlate prostacyclin generation by human endothelial cells 显示文摘 | Brezinski ME Gimbrone MA Jr Nicolaou KC | 1989 | FEBS Lett1989，245，16： | 1 |
| 18 | Transferrin receptor 1 mRNA is downregulated in placenta of hepcidin transgenic embryos 显示文摘 | Martin ME Nicolas G Hetet G Vaulont S Grandchamp B Beaumont C | 2004 | FEBS Lett2004，574，13： | 1 |
| 19 | Lipoxins stimulate prostacyclin generation by human endothelial cells显示文摘 | Brezinski ME Gimbrone MA Jr Nicolaou KC | 1989 | FEBS Lett1989，245，12： | 1 |
| 20 | Short-Term Outcome After Laparoscopic or Open Restorative Mesorectal Excision for Rectal Cancer: A Comparative Cohort Study显示文摘 | Bernard Lelong Thierry Bege Benjamin Esterni Jér?me Guiramand Olivier Turrini Vincent Moutardier Valérie Magnin Geneviève Monges Nicolas Pernoud Jean Louis Blache Marc Giovannini Jean Robert Delpero | 2007 | Diseases of the Colon & Rectum2007，，： | 1 |
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