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| 1 | Hepatic echinococcosis:Clinical and therapeutic aspects显示文摘Echinococcosis or hydatid disease(HD)is a zoonosis caused by the larval stages of taeniid cestodes belonging to the genus Echinococcus.Hepatic echinococcosis is a life-threatening disease,mainly differentiated into alveolar and cystic forms,associated with Echinoccus multilocularis(E.multilocularis)and Echinococcus granulosus(E.granulosus)infection,respectively.Cystic echinococcosis(CE)has a worldwide distribution,while hepatic alveolar echinococcosis(AE)is endemic in the Northern hemisphere,including North America and several Asian and European countries,like France,Germany and Austria.E.granulosus young cysts are spherical,unilocular vesicles,consisting of an internal germinal layer and an outer acellular layer.Cyst expan-sion is associated with a host immune reaction and the subsequent development of a fibrous layer,called the pericyst;old cysts typically present internal septations and daughter cysts.E.multilocularis has a tumorlike,infiltrative behavior,which is responsible for tissue destruction and finally for liver failure.The liver is the main site of HD involvement,for both alveolar and cystic hydatidosis.HD is usually asymptomatic for a long period of time,because cyst growth is commonly slow;the most frequent symptoms are fatigue and abdominal pain.Patients may also present jaundice,hepatomegaly or anaphylaxis,due to cyst leakage or rupture.HD diagnosis is usually accomplished with the combined use of ultrasonography and immunodiagnosis;furthermore,the improvement of surgical techniques,the introduction of minimally invasive treatments[such as puncture,aspiration,injection,re-aspiration(PAIR)]and more effective drugs(such as benzoimidazoles)have deeply changed life expectancy and quality of life of patients with HD.The aim of this article is to provide an up-todate review of biological,diagnostic,clinical and therapeutic aspects of hepatic echinococcosis. | Giuseppe Nunnari Marilia R Pinzone Salvatore Gruttadauria Benedetto M Celesia Giordano Madeddu Giulia Malaguarnera Piero Pavone Alessandro Cappellani Bruno Cacopardo | 2012 | World Journal of Gastroenterology2012，18，13： | 72 |
| 2 | Aetiology of Legg-Calvé-Perthes disease:A systematic review显示文摘BACKGROUND Legg-Calvé-Perthes disease(LCPD) is a clinical condition affecting the femoral head of children during their growth. Its prevalence is set to be between 0.4/100000 to 29.0/100000 children less than 15 years of age with a peak of incidence in children aged from 4 years to 8 years. LCPD aetiology has been widely studied, but it is still poorly understood.AIM To analyse the available literature to document the up-to-date evidence on LCPD aetiology.METHODS A systematic review of the literature was performed regarding LCPD aetiology,using the following inclusion criteria: studies of any level of evidence, reporting clinical or preclinical results and dealing with the aetiology or pathogenesis of LCPD. Two reviewers searched the PubMed and Science Direct databases from their date of inception to the 20th of May 2018 in accordance with the Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. To achieve the maximum sensitivity of the search strategy, we combined the terms: ‘‘Perthes disease OR LCPD OR children avascular femoral head necrosis' with 'pathology OR aetiology OR biomechanics OR genetics' as either key words or MeSH terms.RESULTS We include 64 articles in this review. The available evidence on LCPD aetiology is still debated. Several hypotheses have been researched, but none of them was found decisive. While emerging evidence showed the role of environmental risk factors and evidence from twin studies did not support a major role for genetic factors, a congenital or acquired predisposition cannot be excluded in disease pathogenesis. One of the most supported theories involved mechanical induced ischemia that evolved into avascular necrosis of the femoral head in sensible patients.CONCLUSION The literature available on the aetiology of LCPD presents major limitations in terms of great heterogeneity and a lack of high-profile studies. Although a lot of studies focused on the genetic, biomechanical and radiological background of the disease, there is a lack of consensus on one or multiple major actors of the etiopathogenesis. More studies are needed to understand the complex and multifactorial genesis of the avascular necrosis characterizing the disease. | Vito Pavone Emanuele Chisari Andrea Vescio Claudio Lizzio Giuseppe Sessa Gianluca Testa | 2019 | World Journal of Orthopedics2019，10，3： | 7 |
| 3 | Arthroereisis in juvenile flexible flatfoot:Which device should we implant?A systematic review of literature published in the last 5 years显示文摘BACKGROUND Flexible flatfoot(FFF)is a very common condition in children,characterized by the loss of the medial arch and by an increase in the support base with valgus of the hindfoot.Arthroereisis(AR)procedures are widely performed corrective surgeries and are classified as subtalar AR and calcaneo-stop(CS).AIM We investigated the literature published in the last 5 years with the aim of providing an update on the evidence related to AR treatment in FFF patients.We report the principal findings of subtalar AR and CS procedures concerning clinical and radiological outcomes and complication rates in the general population,young athletes,and obese people according to material device.METHODS Following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses,a systematic review of studies published in the past 5 years and included the PubMed and Science Direct databases was performed on May 6,2020.The research string used was(pediatric OR children OR Juvenile NOT adult)AND(flexible NOT rigid)AND(flat foot OR pes planus)AND(calcaneo-Stop OR arthroereisis OR subtalar extra-articular screw OR SESA OR subtalar arthroereisis OR endosinotarsal).The risk of bias assessment was performed using the Dutch checklist form for prognosis.RESULTS A total of 47 articles were found.Ultimately,after reading the full text and checking reference lists,we selected 17 articles that met the inclusion and exclusion criteria.A total of 1864 FFFs were identified.Eight studies concerned the subtalar AR(47.1%)and nine concerning CS(52.9%).The average age of patients at start of treatment was 11.8 years,the average follow-up of the studies was 71.9 mo(range 29.1-130).Globally,complications occurred in 153 of the 1864 FFF treated,with a rate of 8.2%.CONCLUSION Both AR procedures are valid surgical techniques for treating FFF.Surgeon experience,implant cost,and cosmetic correction are the most common considerations included in the orthopedic device decision-making process.In obese patients,the subtalar AR is not recommended.In adolescents who need to improve sports performance,the CS screw had better results compared with other implants. | Andrea Vescio Gianluca Testa Mirko Amico Claudio Lizzio Marco Sapienza Piero Pavone Vito Pavone | 2021 | World Journal of Orthopedics2021，12，6： | 3 |
| 4 | Unveiling the controversial mechanism of reversible Na storage in TiO2 nanotube arrays: Amorphous versus anatase TiO2显示文摘由于他们的固有的安全,低费用,和结构的稳定性, TiO 2 nanostructures 在钠离子电池作为阳极材料代表一种合适的选择。在最近的年里,各种各样的假设在 TiO 2 结构关于钠离子的可逆插入的实际机制被建议了,并且以前的报告在这个方面经常是争论的。有趣地,当作为文件夹测试了时 -- 并且在实验室规模钠房间进行没有添加剂的电极,非结晶、水晶(锐钛矿) 简单阳极的氧化获得的 TiO 2 nanotubular 数组展出古怪、内在地不同的电气化学的回答。在起始的电气化学的激活以后,特别地,锐钛矿 TiO 2 与更大的特定的能力显示出优秀的率能力和很稳定的长期的骑车性能,并且这样清楚地优异的回答与非结晶的对应物相比。获得更深的卓见,现在的材料被在 TiO 2 体积阶段扫描钠离子的电子显微镜学和前 situ X 光检查衍射,和插入彻底地描绘被密度系统地建模功能的理论计算。现在的结果可以贡献更系统的屏蔽途径的开发为高度有效的基于钠的精力存储系统识别合适的活跃材料。 | Federico Bella Ana B. Munoz-Garcia Giuseppina Meligrana Andrea Lamberti Matteo Destro Michele Pavone Claudio Gerbaldi | 2017 | Nano Research2017，10，8： | 2 |
| 5 | OSI Service Specification:SAP and CEP Modeling显示文摘 | JG Tomas J Pavon O Pereda | 1987 | ACM SIGCOMM Computer Communiation Review1987，17，12： | 2 |
| 6 | ~ion-steroidal anti-inflammatory drugs attenuate the vascular responses in aging metabolic syndrome rats显示文摘 | Maria Esther RUBIO-RUIZ Israel PEREZ-TORRES Eulises DIAZ-DIAZ Natalia PAVON Veronica GUARNER-LANS | 2014 | Acta Pharmacologica Sinica2014，35，11： | 2 |
| 7 | Minimally invasive total hip arthroplasty: a prospective randomized study 显示文摘 | Chimento GF Pavone V Sharrock N | 2005 | J Arthroplasty2005，20，： | 1 |
| 8 | Proteomics characterization of protein adsorption onto hemodialysis membranes显示文摘 | Bonomini M Pavone B Sirolli V | 2006 | J Proteome Res2006，5，10： | 1 |
| 9 | Epidennal nevus syndrome:A neurologic variant with hemimegalencephaly, gyral malformation, mental retardation,seizures and facial hemihypertrophy显示文摘 | Pavone L Curatolo P Rizzo R | 1991 | Neurology1991，41，2： | 1 |
| 10 | On-line preconcentration using chelating and ion-exchange minicolumns for the speciation of chromium(iii) and chrontium(vi) and their quantitative determination in natural waters by inductively coupled plasma mass spectrometry显示文摘 | GUERRERO M M L ALONSO E V PAVON J M C | 2012 | Journal of Analytical Atomic Spectrometry2012，27，4： | 1 |
| 11 | The impact of insulin secretion on the ovarian response to exogenous gonadotropins in polycystic ovary syndrome 显示文摘 | Fulghesu AM Villa P Pavone V | 1997 | J Clin Endocrinol Meta1997，82，2： | 1 |
| 12 | Observation and correlations for immiscible viscous-fingering experiments 显示文摘 | Dldler Pavone | 1992 | SPE 196701992，，： | 1 |
| 13 | Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression显示文摘 | ALONSO R GRIEBEL G PAVONE G | 2004 | Mol Psychiatry2004，9，22： | 1 |
| 14 | Aggression in psychiat / wards: A systematic review 显示文摘 | Cornaggia CM Beghi M Pavone F | 2011 | Psychiatry Reseach2011，1，1： | 1 |
| 15 | Determination offilbertone in spiked olive oil samples using headspace-programmed temperature vaporization-gas chromatography-mass spectrometry 显示文摘 | PEREZ PAVON JL DEL NOGAL SANCHEZ M PERNANDEZ LAESPADA ME | 2009 | Analytical and Bioanalytical Chemistry2009，394，5： | 1 |
| 16 | Ultraviolet-B irradiation alters the cell cycle machinery in murine epidermis in vivo显示文摘 | Berton TR Pavone A Fischer SM | 2001 | J Invest Dermatol2001，117，5： | 1 |
| 17 | Radiology information and image management system:new approach to PACS with hypermedia capabilities of personal computers显示文摘 | PAVONE P MARSELLA M PANEBIANCE V | 1996 | RadioGraphics1996，16，2： | 1 |
| 18 | The flexible cystoscope 显示文摘 | Lammartina M Pavone C | 1992 | Int Urol Nephrol1992，24，3： | 1 |
| 19 | Poor mobilization is an independent prognostic factor in patients with malignant lymphomas treated by peripheral blood stem cell transplantation 显示文摘 | Pavone V Gaudio F Console G | 2006 | Bone Marrow Transplant2006，37，8： | 1 |
| 20 | The impact of insulin secretion on the ovarian response to exogenous gonadotropins in polycystic ovary syndrome显示文摘 | Fulghesu AM Villa P Pavon V | | 0，，： | 1 |
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