|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | MR扩散加权成像诊断食管癌的效能显示文摘本研究目的是评价DWI对检出食管癌及评估淋巴结的价值,并与组织病理学对照。对连续24例食管癌病人前瞻性进行背景信号抑制的全身扩散加权成像(DWIBS)。将DWIBS影像与T2WI影像融合,由3名有资质的放射科医师独立盲法分析,内容包括原发肿瘤的检出能力及淋巴结状况,并测量原发肿瘤和淋巴结的表观扩散系数(ADC)。原发肿瘤的平均检出率为49.4%,以病人为目标的淋巴结转移检出的敏感度和特异度分别为77.8%和55.6%, | A. Sakurada T. Takahara T.C. Kwee T. Yamashita S. Nasu T. Horie 王萍(译) 刘筠(校) | 2009 | 国际医学放射学杂志2009，32，4： | 40 |
| 2 | Role of diffusion-weighted magnetic resonance imaging in the differential diagnosis of focal hepatic lesions显示文摘AIM:To evaluate the utility of diffusion-weighted im-aging(DWI)in screening and differential diagnosis of benign and malignant focal hepatic lesions.METHODS:Magnetic resonance imaging(MRI)ex-aminations were performed using the Signa Excite Xl Twin Speed 1.5T system(GE Healthcare,Milwaukee,WI,USA).Seventy patients who had undergone MRI of the liver [29 hepatocellular carcinomas(HCC),four cholangiocarcinomas,34 metastatic liver cancers,10 hemangiomas,and eight cysts] between April 2004 and August 2008 were retrospectively evaluated.Visu-alization of lesions,relative contrast ratio(RCR),and apparent diffusion coefficient(ADC)were compared between benign and malignant lesions on DWI.Su-perparamagnetic iron oxide(SPIO)was administered to 59 patients,and RCR was compared pre-and post-administration.RESULTS:DWI showed higher contrast between ma-lignant lesions(especially in multiple small metastatic cancers)and surrounding liver parenchyma than did contrast-enhanced computed tomography.ADCs(mean ± SD × 10-3 mm2/s)were signif icantly lower(P < 0.05)in malignant lesions(HCC:1.31 ± 0.28 and liver me-tastasis:1.11 ± 0.22)and were signifi cantly higher in benign lesions(hemangioma:1.84 ± 0.37 and cyst:2.61 ± 0.45)than in the surrounding hepatic tissues.RCR between malignant lesions and surrounding he-patic tissues signifi cantly improved after SPIO adminis-tration,but RCRs in benign lesions were not improved.CONCLUSION:DWI is a simple and sensitive method for screening focal hepatic lesions and is useful for dif-ferential diagnosis. | Naoto Koike Akihiro Cho Katsuhiro Nasu Kazuhiko Seto Shigeyuki Nagaya Yuji Ohshima Nobuhiro Ohkohchi | 2009 | World Journal of Gastroenterology2009，15，46： | 38 |
| 3 | A prospective, multicenter study of 1111 colorectal endoscopic submucosal dissections (with video)显示文摘 | Yutaka Saito Toshio Uraoka Yuichiro Yamaguchi Kinichi Hotta Naoto Sakamoto Hiroaki Ikematsu Masakatsu Fukuzawa Nozomu Kobayashi Junichirou Nasu Tomoki Michida Shigeaki Yoshida Hisatomo Ikehara Yosuke Otake Takeshi Nakajima Takahisa Matsuda Daizo Saito | 2010 | Gastrointestinal Endoscopy2010，，6： | 6 |
| 4 | Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study显示文摘 | Narikazu Boku Seiichiro Yamamoto Haruhiko Fukuda Kuniaki Shirao Toshihiko Doi Akira Sawaki Wasaburo Koizumi Hiroshi Saito Kensei Yamaguchi Hiroya Takiuchi Junichiro Nasu Atsushi Ohtsu | 2009 | Lancet Oncology2009，，11： | 5 |
| 5 | 精力的文学评论为执行 laparoscopic colorectal 外科采购原料显示文摘 Laparoscopic surgery for colorectal disease has become widespread as a minimally invasive treatment.This is important because the increasing availability of new devices allows us to perform procedures with a reduced length of surgery and decreased blood loss.We herein report the results of a literature review of energy sources for laparoscopic colorectal surgery,focused especially on 6 studies comparing ultrasonic coagulating shears(UCS) and other instruments.We also describe our laparoscopic dissection techniques using UCS for colorectal cancer.The short-term outcomes of surgeries using UCS and Ligasure for laparoscopiccolorectal surgery were superior to conventional electrosurgery.Some authors have reported that the length of surgery or blood loss when Ligasure was used for laparoscopic colorectal surgery is less than when UCS was used.On the other hand,a recent study demonstrated that there were no significant differences between the short-term outcomes of UCS and Ligasure for laparoscopic colorectal surgery.It is therefore suggested that the choice of technique used should be made according to the surgeon’s preference.We also describe our laparoscopic dissection techniques using UCS(Harmonic ACE) for colorectal cancer with regard to the retroperitoneum dissection,dissection technique,dissection technique around the feeding artery,and various other dissection techniques.We therefore review the outcomes of using various energy sources for laparoscopic colorectal surgery and describe our laparoscopic dissection techniques with UCS(Harmonic ACE) for colorectal cancer. | Tsukasa Hotta Katsunari Takifuji Shozo Yokoyama Kenji Matsuda Takashi Higashiguchi Toshiji Tominaga Yoshimasa Oku Takashi Watanabe Toru Nasu Tadamichi Hashimoto Koichi Tamura Junji Ieda Naoyuki Yamamoto Hiromitsu Iwamoto Hiroki Yamaue | 2012 | World Journal of Gastrointestinal Surgery2012，4，1： | 4 |
| 6 | Micromolar sodium fluoride mediates anti-osteoclastogenesis in Porphyromonas gingivalis-induced alveolar bone loss显示文摘Osteoclasts are bone-specific multinucleated cells generated by the differentiation of monocyte/macrophage lineage precursors.Regulation of osteoclast differentiation is considered an effective therapeutic approach to the treatment of bone-lytic diseases.Periodontitis is an inflammatory disease characterized by extensive bone resorption. In this study, we investigated the effects of sodium fluoride(Na F) on osteoclastogenesis induced by Porphyromonas gingivalis, an important colonizer of the oral cavity that has been implicated in periodontitis. Na F strongly inhibited the P. gingivalis-induced alveolar bone loss. That effect was accompanied by decreased levels of cathepsin K, interleukin(IL)-1β, matrix metalloproteinase 9(MMP9), and tartrate-resistant acid phosphatase,which were up-regulated during P. gingivalis-induced osteoclastogenesis. Consistent with the in vivo anti-osteoclastogenic effect,Na F inhibited osteoclast formation caused by the differentiation factor RANKL(receptor activator of nuclear factor kB ligand)and macrophage colony-stimulating factor(M-CSF). The RANKL-stimulated induction of the transcription factor nuclear factor of activated T cells(NFAT) c1 was also abrogated by Na F. Taken together, our data demonstrate that Na F inhibits RANKL-induced osteoclastogenesis by reducing the induction of NFATc1, ultimately leading to the suppressed expression of cathepsin K and MMP9.The in vivo effect of Na F on the inhibition of P. gingivalis-induced osteoclastogenesis strengthens the potential usefulness of Na F for treating periodontal diseases. | Ujjal K Bhawal Hye-Jin Lee Kazumune Arikawa Michiharu Shimosaka Masatoshi Suzuki Toshizo Toyama Takenori Sato Ryota Kawamata Chieko Taguchi Nobushiro Hamada Ikuo Nasu Hirohisa Arakawa Koh Shibutani | 2015 | International Journal of Oral Science2015，7，4： | 3 |
| 7 | A novel preoperative fusion analysis using three-dimensional MDCT combined with three-dimensional MRI for patients with hilar cholangiocarcinoma显示文摘 | Yukio Oshiro Ryoko Sasaki Katsuhiro Nasu Nobuhiro Ohkohchi | 2013 | Clinical Imaging2013，，4： | 2 |
| 8 | Endoscopic retrograde cholangiopancreatography for bile duct stones in patients with a performance status score of 3 or 4显示文摘BACKGROUND As the aging population grows worldwide,the rates of endoscopic retrograde cholangiopancreatography(ERCP)for common bile duct stones(CBDS)in older patients with a poor performance status(PS)have been increasing.However,the data on the safety and efficacy of ERCP for CBDS in patients with a PS score of 3 or 4 are lacking,with only a few studies having investigated this issue among patients with poor PS.AIM To examine the safety and efficacy of ERCP for CBDS in patients with a PS score of 3 or 4.METHODS This study utilized a retrospective multi-centered design of three institutions in Japan for 8 years to identify a total of 1343 patients with CBDS having native papillae who underwent therapeutic ERCP.As a result,1113 patients with a PS 0-2 and 230 patients with a PS 3-4 were included.One-to-one propensity-score matching was performed to compare the safety and efficacy of ERCP for CBDS between patients with a PS 0-2 and those with a PS 3-4.RESULTS The overall ERCP-related complication rates in all patients and propensity score-matched patients with a PS 0-2 and 3-4 were 9.0%(100/1113)and 7.0%(16/230;P=0.37),and 4.6%(9/196)and 6.6%(13/196;P=0.51),respectively.In the propensity score-matched patients,complications were significantly more severe in the group with a PS 3-4 than in the group with a PS 0-2 group(P=0.042).Risk factors for complications were indications of ERCP and absence of antibiotics in the multivariate analysis.Therapeutic success rates,including complete CBDS removal and permanent biliary stent placement,in propensity score-matched patients with a PS 0-2 and 3-4 were 97.4%(191/196)and 97.4%(191/196),respectively(P=1.0).CONCLUSION ERCP for CBDS can be effectively performed in patients with a PS 3 or 4.Nevertheless,the indication for ERCP in such patients should be carefully considered with prophylactic antibiotics. | Hirokazu Saito Yoshihiro Kadono Takashi Shono Kentaro Kamikawa Atsushi Urata Jiro Nasu Haruo Imamura Ikuo Matsushita Tatsuyuki Kakuma Shuji Tada | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，4： | 2 |
| 9 | Risk Factors for Metachronous Gastric Cancer in the Remnant Stomach After Early Cancer Surgery显示文摘 | Isao Nozaki Junichirou Nasu Yoshiro Kubo Minoru Tanada Rieko Nishimura Akira Kurita | 2010 | World Journal of Surgery2010，，7： | 2 |
| 10 | Drug combinations with amoxycillin reduce selection of clarithromycin resistance during Helicobacter pylori eradication therapy显示文摘 | K Murakami T Fujioka T Okimoto R Sato M Kodama M Nasu | 2002 | International Journal of Antimicrobial Agents2002，，1： | 2 |
| 11 | Metachronous penile metastasis from rectal cancer after total pelvic exenteration显示文摘Despite its abundant vascularization and extensive circulatory communication with neighboring organs, metastases to the penis are a rare event. A 57-yearold male, who had undergone total pelvic exenteration for rectal cancer sixteen months earlier, demonstrated an abnormal uptake within his penis by positron emission tomography/computed tomography. A single elastic nodule of the middle penis shaft was noted deep within Bucks fascia. No other obvious recurrent site was noted except the penile lesion. Total penectomy was performed as a curative resection based on a diagnosis of isolated penile metastasis from rectal cancer. A histopathological examination revealed an increase of well differentiated adenocarcinoma in the corpus spongiosum consistent with his primary rectal tumor. The immunohistochemistry of the tumor cells demonstrated positive staining for cytokeratin 20 and negative staining for cytokeratin 7, which strongly supported a diagnosis of penile metastasis from the rectum. The patient is alive more than two years without any recurrence. | Yuta Kimura Keiichi Nasu Hiroki Matsunaga Masahiro Warabi Satoru Inoue | 2012 | World Journal of Gastroenterology2012，18，38： | 2 |
| 12 | 感染高原属兔的皮蝇蛆Ⅲ期幼虫的电镜形态学比较研究显示文摘为了观察感染高原鼠兔与感染牦牛、藏羚羊的皮蝇蛆Ⅲ期幼虫之间形态学上的区别,在青海省玉树县和称多县收集感染高原鼠兔的皮蝇蛆与本研究室以往收集保存的感染牦牛、藏羚羊皮蝇蛆进行比较研究。取出蝇蛆晾干酒精,用戊二醛液固定,切下幼虫的头部和尾部用锇酸溶液固定,不同浓度的酒精脱水、临界点干燥、表面喷金后,扫描电镜观察。感染鼠兔的皮蝇蛆伪头部口裂背侧没有明显的肉质突起,腹面棘成连续的1簇,伪头突起与口裂之间有许多细密的小棘,气门板稍凸起,圆形,上面无棘;第10节腹面前缘棘大,圆形,后缘棘小,散在。与感染牦牛的牛皮蝇蛆、纹皮蝇蛆、中华皮蝇蛆及感染藏羚羊的皮蝇蛆在形态上有明显的区别。 | 朵红 Tetsuo Nasu 李伟 吴润 | 2012 | 寄生虫与医学昆虫学报2012，19，2： | 2 |
| 13 | 带磁性标记器的钢芯铝绞线精确长度测量系统显示文摘前言近来预制件在架设高压线路中已变得通行起来。要成功地应用这种方法,必须高度精确地测量电缆。以前用计算要求的线路垂度和在塔顶上的工人调整长度的办法来架设传输线路,但这种方法既危险成本又高,要想重新架设现有线路必须断电很长时间。对预制加工是消除这些不利因素的积极办法,预制加工电缆的需求每年增长40%,这便是明显的证据。为了应付这种需求,研制了一种高精度、高速长度测量系统。 | Yoshihiro Nasu 马庆文 | 1989 | 电线电缆1989，，4： | 2 |
| 14 | XAFS Study on Solid State Amorphization of Alloys by Mechanical Alloying显示文摘Structural evolution of alloys by ball milling during solid state amorphization were studied by means of XAFS technique. The first one is amorphization process of Fe and B powder mixtures by mechanical alloying (MA), and the second one is amorphization process of ordered B2 CoZr intermetallic compound by mechanical milling (MM). The mixing process of Fe and B and disintegration process of ordered B2 CoZr intermetallic compound crystal were observed clearly in atomic level by XAFS method. The micro mechanism of amorphization process of alloy by ball milling was discussed. | Nasu,T Sakurai,M | 2001 | 中国科学技术大学学报2001，31，3： | 2 |
| 15 | Quantification and distribution of alpha 1-adrenoceptor subtype mRNAs in human prostate:comparison of benign hypertrophied tissue and non-hypertrophied tissue显示文摘 | Nasu K Moriyama N Kawabe K | 1996 | Br J Pharmacol1996，119，5： | 1 |
| 16 | Survivin mRNA expression in patients with breast cancer显示文摘 | Nasu S Yagihashi A Izawa A | 2002 | Anticancer Res2002，22，3： | 1 |
| 17 | Effects of fruit, spices and herbs on α glucosidase activity and glycemic index显示文摘 | NASU R MIURA M GOMYO T | 2005 | Food Sci Technol Res2005，11，1： | 1 |
| 18 | Seismic response controlled structures with active variable stiffness system显示文摘 | Kobori T Takahashi M Nasu T | 1993 | Earthquake Engineering and Structural Dynamics1993，23，： | 1 |
| 19 | survivin mRNA expression in patients with breast eaneer显示文摘 | Nasu S Yagihashi A Izawa A | 2002 | Antieaneer Res2002，22，3： | 1 |
| 20 | Prevalence of pocine endogenous retrovirus in domestic pigs in Japan and its potential infection in dogs xenotransplanted with porcine pancreatic islet cells显示文摘 | Edamura K Nasu K lwami Y | 2004 | J Vet Med Sci2004，66，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员