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| 1 | 阴茎转移癌6例报告及文献复习显示文摘目的:探讨阴茎转移癌的诊断和治疗特点。方法:结合文献,对6例阴茎转移癌的诊断、临床表现、病理、治疗及预后进行分析。结果:6例阴茎转移癌中,原发肿瘤肺来源2例(其中1例为罕见的肺上皮样血管内皮瘤),膀胱来源2例,肝来源1例,前列腺来源1例。6例中5例表现为阴茎硬结,其中3例合并阴茎胀痛感,1例合并急性尿潴留,1例为阴茎异常勃起。6例均接受手术切除、化疗或放疗,随访至今,1例存活,5例病死。结论:肿瘤转移至阴茎非常少见,预后极差,手术切除联合化疗、放疗或内分泌治疗可改善症状,但不能延长生命。 | 单勇 徐明曦 王忠 张克 | 2014 | 中国临床医学2014，21，6： | 3 |
| 2 | Metachronous isolated penile metastasis from sigmoid colon adenocarcinoma:A case report显示文摘BACKGROUND Sigmoid colon adenocarcinoma has a high incidence among gastrointestinal tumors,and it very rarely metastasizes to the penis.The literature reports that the prognosis after penile metastasis is generally poor,with a median survival of about 9 mo.Metachronous isolated metastasis to the penis originating from sigmoid colon adenocarcinoma has not been reported so far.Here,we report a case of sigmoid colon adenocarcinoma with isolated penile metastasis occurring 2 years after surgery.The mass was pathologically confirmed as metastatic adenocarcinoma,and oral chemotherapy with capecitabine was given after surgery.The tumor did not recur during the 2-year follow-up period.CASE SUMMARY A 79-year-old man presented to the urology department with'a mass located at the root of the penis since 1 mo'.Enhanced computed tomography(CT)examination suggested a 12 mm×10 mm×9 mm nodule at the root of the right penile corpus cavernosum.Cranial,pulmonary,and abdominal CT;and bone scan did not show any tumorigenic lesions.The carcinoembryonic antigen(CEA)level was slightly elevated(6.01 ng/mL,reference value 0-5 ng/mL).The patient had undergone laparoscopic radical sigmoidectomy for sigmoid colon cancer 2 years ago.The postoperative pathology showed moderately differentiated adenocarcinoma of the sigmoid colon,and the stage was PT2N0M0.The penile mass was removed under general anesthesia.The postoperative pathology showed adenocarcinoma,and immunohistochemistry showed CDX2(+),CK20(+),and Villin(+).Based on the medical history,he was diagnosed with penile metastasis from sigmoid colon adenocarcinoma.The CEA level returned to normal(3.34 ng/mL)4 d after surgery.Oral chemotherapy with capecitabine was given subsequently,and tumor recurrence was not found during the 2-year follow-up period.CONCLUSION To our knowledge,this is a rare case of metachronous isolated penile metastasis from sigmoid colon adenocarcinoma.The penis is a potential site of metastasis of colon adenocarcinoma,and the possibility of metastasis should be considered in patients with a history of colon cancer who present with a penile mass.Solitary penile metastasis can be removed surgically,in combination with chemotherapy,and it may have good long-term outcomes. | Guo-Lin Yin Jiang-Bo Zhu Cheng-Lin Fu Ru-Liang Ding Jun-Miao Zhang Qian Lin | 2022 | World Journal of Clinical Cases2022，10，31： | 0 |
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