|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Does training and experience influence the accuracy of computed tomography colonography interpretation?显示文摘AIM: To evaluate the effect of experience on the accuracy rate of computed tomography colonography(CTC) interpretation and patient preferences/satisfaction for CTC and colonoscopy. METHODS: A prospective, non-randomized, observational study performed in a single, tertiary care center involving 90 adults who underwent CTC followed by colonoscopy on the same day. CTC was interpreted by an abdominal imaging radiologist and then a colonoscopy was performed utilizing segmental un-blinding and re-examination as required. A radiology resident and two gastroenterology(GI) fellows blinded to the results also interpreted the CTC datasets independently. Accuracy rates and trend changes were determined for each reader to assess for a learning curve. RESULTS: Among 90 patients(57% male) aged 55 ± 8.9 years, 39 polyps ≥ 6 mm were detected in 20 patients and 13 polyps > 9 mm in 10 patients. Accuracy rates were 88.9%(≥ 6 mm) and 93.3%(> 9 mm) for the GI Radiologist, 89.8%(≥ 6 mm) and 98.9%(> 9 mm) for the Radiology Resident and 86.7% and 95.6%(≥ 6 mm) and 87.8% and 94.4%(> 9 mm) for each of the GI fellows respectively. The reader's accuracy rate did not change significantly with the percentage change rate ranging between-1.7 to 0.9(P = 0.12 to 0.56). Patients considered colonoscopy more satisfactory than CTC(30% vs 4%, P < 0.0001), they felt less anxiety during colonoscopy(36% vs 7%, P < 0.0001), they experienced less pain or discomfort during colonoscopy compared to CTC(69% vs 4%, P < 0.0001) and colonoscopy was preferred by 77% of the participants as a repeat screening test for the future. CONCLUSION: No statistically significant learning curve was identified in CTC interpretation suggesting that further study is required to identify the necessary training to adequately interpret CTC scans. | Greg Rosenfeld Yi Tzu Nancy Fu Brendan Quiney Hong Qian Darin Krygier Jacquie Brown Patrick Vos Pari Tiwari Jennifer Telford Brian Bressler Robert Enns | 2014 | World Journal of Gastroenterology2014，20，6： | 2 |
| 2 | Transition clinic attendance is associated with improved beliefs and attitudes toward medicine in patients with inflammatory bowel disease显示文摘AIM To evaluated the differences in knowledge, adherence, attitudes, and beliefs about medicine in adolescents with inflammatory bowel disease(IBD) attending transition clinics.METHODS We prospectively enrolled patients from July 2012 to June 2013. All adolescents who attended a tertiarycentre-based dedicated IBD transition clinic were invited to participate. Adolescent controls were recruited from university-affiliated gastroenterology offices. Participants completed questionnaires about their disease and reported adherence to prescribed therapy. Beliefs in Medicine Questionnaire was used to evaluate patients' attitudes and beliefs. Beliefs of medication overuse, harm, necessity and concerns were rated on a Likert scale. Based on necessity and concern ratings, attitudes were then characterized as accepting, ambivalent, skeptical and indifferent. RESULTS One hundred and twelve adolescents were included and 59 attended transition clinics. Self-reported adherence rates were poor, with only 67.4% and 56.8% of patients on any IBD medication were adherent in the transition and control groups, respectively. Adolescents in the transition cohort held significantly stronger beliefs that medications were necessary(P = 0.0035). Approximately 20% of adolescents in both cohorts had accepting attitudes toward their prescribed medicine. However, compared to the control group, adolescents in the transition cohort were less skeptical of(6.8% vs 20.8%) and more ambivalent(61% vs 34%)(OR = 0.15; 95%CI: 0.03-0.75; P = 0.02) to treatment.CONCLUSION Attendance at dedicated transition clinics was associated with differences in attitudes in adolescents with IBD. | Nancy Fu Kevan Jacobson Andrew Round Kathi Evans Hong Qian Brian Bressler | 2017 | World Journal of Gastroenterology2017，23，29： | 2 |
| 3 | Performance of interferon‐gamma release assays in patients with inflammatory bowel disease: A systematic review and meta‐analysis显示文摘 | Neal Shahidi Yi‐Tzu Nancy Fu Hong Qian Brian Bressler | 2012 | Inflamm Bowel Dis2012，，： | 1 |
| 4 | Freeze-Dried Strawberries Lower Serum Cholesterol and Lipid Peroxidation in Adults with Abdominal Adiposity and Elevated Serum Lipids1-3显示文摘 | Basu Arpita Betts Nancy M Nguyen Angel Newman Emily D Fu Dongxu Lyons Timothy J | 2014 | The Journal of Nutrition2014，，： | 1 |
| 5 | Impact of a Health Literacy Intervention on Pediatric Emergency Department Use显示文摘 | Ariella Herman Kelly D. Young Dennis Espitia Nancy Fu Arta Farshidi | 2009 | Pediatric Emergency Care2009，，7： | 1 |
| 6 | Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience显示文摘 | Nancy Lee Ping Xia Jeanne M Quivey Khalil Sultanem Ian Poon Clayton Akazawa Pam Akazawa Vivian Weinberg Karen K Fu | 2002 | International Journal of Radiation Oncology Biology Physics2002，，1： | 1 |
| 7 | Anomalous high ionic conductivity of nanoporous β-Li3PS4显示文摘 | Liu Zengcai Fu Wujun Andrew Payzant E Yu Xiang Wu Zili Dudney Nancy J Jim Kiggans Hong Kunlun Rondinone Adam J Liang Chengdu | 2013 | Journal of the American Chemical Society2013，135，： | 1 |
| 8 | MUC1 is expressed at high frequency in early-stage basal-like triple-negative breast cancer显示文摘 | Alan Siroy Fadi W. Abdul-Karim John Miedler Nancy Fong Pingfu Fu Hannah Gilmore Joseph Baar | 2013 | Human Pathology2013，，： | 1 |
| 9 | Impact of medical therapy on patients with Crohn's disease requiring surgical resection显示文摘AIM: To evaluate the impact of medical therapy on Crohn's disease patients undergoing their first surgical resection.METHODS: We retrospectively evaluated all patients with Crohn's disease undergoing their first surgical resection between years 1995 to 2000 and 2005 to 2010 at a tertiary academic hospital(St. Paul's Hospital, Vancouver, Canada). Patients were identified from hospital administrative database using the International Classification of Diseases 9 codes. Patients' hospital and available outpatient clinic records were independently reviewed and pertinent data were extracted. We explored relationships among time from disease diagnosis to surgery, patient phenotypes, medication usage, length of small bowel resected, surgical complications, and duration of hospital stay.RESULTS: Total of 199 patients were included; 85 from years 1995 to 2000(cohort A) and 114 from years 2005 to 2010(cohort B). Compared to cohort A, cohort B had more patients on immunomodulators(cohort A vs cohort B: 21.4% vs 56.1%, P < 0.0001) and less patients on 5-aminosalysilic acid(53.6% vs 29.8%, P = 0.001). There was a shift from inflammatory to stricturing and penetrating phenotypes(B1/B2/B3 38.8% vs 12.3%, 31.8% vs 45.6%, 29.4% vs 42.1%, P < 0.0001). Both groups had similar median time to surgery. Within cohort B, 38 patients(33.3%) received anti-tumor necrosis factor(TNF) agent. No patient in cohort A was exposed to anti-TNF agent. Compared to patients not on anti-TNF agent, ones exposed were younger at diagnosis(anti-TNF vs without anti-TNF: A1/A2/A3 39.5% vs 11.8%, 50% vs 73.7%, 10.5% vs 14.5%, P = 0.003) and had longer median time to surgery(90 mo vs 48 mo, P = 0.02). Combination therapy further extended median time to surgery. Using timedependent multivariate Cox proportional hazard model, patients who were treated with anti-TNF agents had a significantly higher risk to surgery(adjusted hazard ratio 3.57, 95%CI: 1.98-6.44, P < 0.0001) compared to those without while controlling for gender, disease phenotype, smoking status, and immunomodulator use.CONCLUSION: Significant changes in patient phenotypes and medication exposures were observed between the two surgical cohorts separated by a decade. | YT Nancy Fu Thomas Hong Andrew Round Brian Bressler | 2014 | World Journal of Gastroenterology2014，20，33： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员