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628篇 您的检索式:作者名="Musso"
    题名 作者 年代 出处 被引量
1Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity显示文摘Giovanni Musso Roberto Gambino Maurizio Cassader Gianfranco Pagano 2011Annals of Medicine2011,,8:8
2Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials显示文摘G. Musso M. Cassader F. Rosina R. Gambino 2012Diabetologia2012,,4:7
3Prokineticin 2/Bv8 is expressed in Kupffer cells in liver and is down regulated in human hepatocellular carcinoma显示文摘AIM: To study the implication of prokineticin 1 (PK1/EG- VEGF) and prokineticin 2 (PK2/Bv8) in hepatocellular carcinoma angiogenesis. METHODS: The gene induction of PK1/EG-VEGF and PK2/Bv8 was investigated in 10 normal, 28 fibrotic and 28 tumoral livers by using real time PCR. Their expression was compared to the expression of VEGF (an angiogenesis marker), vWF (an endothelial cell marker) and to CD68 (a monocyte/macrophage marker). Furthermore, the mRNA levels of PK1/EG-VEGF, PK2/Bv8, prokineticin receptor 1 and 2 were evaluated by real time PCR in isolated liver cell populations. Finally, PK2/Bv8 protein was detected in normal liver paraffin sections and in isolated liver cells by immunohistochemistry and immunocytochemistry. RESULTS: PK2/Bv8 mRNA but not PK1/EG-VEGF was expressed in all types of normal liver samples examined. In the context of liver tumor development, we reported that PK2/Bv8 correlates only with CD68 and showed a significant decrease in expression as the pathology evolves towards cancer. Whereas, VEGF and vWF mRNA were significantly upregulated in both fibrosis and HCC,as expected. In addition, out of all isolated liver cells examined, only Kupffer cells (liver resident macrophages) express significant levels of PK2/Bv8 and its receptors, prokineticin receptor 1 and 2. CONCLUSION: In normal liver PK2/Bv8 and its receptors were specifically expressed by Kupffer cells. PK2/Bv8 expression decreased as the liver evolves towards cancer and did not correlate with HCC angiogenesis.Justin Monnier Claire Piquet-Pellorce Jean-Jacques Feige Orlando Musso Bruno Clément Bruno Turlin Nathalie Théret Michel Samson 2008World Journal of Gastroenterology2008,14,8:4
4Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepatocellular carcinoma显示文摘Elisabetta Bugianesi Nicola Leone Ester Vanni Giulio Marchesini Franco Brunello Patrizia Carucci Alessandro Musso Paolo De Paolis Lorenzo Capussotti Mauro Salizzoni Mario Rizzetto 2002Gastroenterology2002,,1:4
5北美典型气候区建筑围护结构HM模拟及分析显示文摘为明确气候参数、材料参数对建筑围护结构模拟结果的影响,以及热湿耦合传递模型(HM)和被普遍采用的Glaser模型之间的差异,在热湿过程模拟软件WUFI Plus中选择北美典型气候区的20个代表城市,设置15组外墙构件,进行空间单元HVAC需求、室内热湿环境和外墙热湿性能的全年模拟.模拟结果与室外气候参数进行相关性分析,表明室外气温、太阳辐射、相对湿度和风驱雨不同程度地影响相关结果.通过材料参数控制所得2组HM和3组Glaser模型的对比,表明液态水相关参数、含湿量引起的材料参数的变物性取值对模拟结果有显著影响.北美典型气候区HM模拟对我国建筑围护结构热湿过程相关的气候参数、材料参数和评估方法的研究具有借鉴意义.黄祖坚 孙一民 MUSSO Florian 2019湖南大学学报(自然科学版)2019,46,3:3
6Dimensions of hepatocellular carcinoma phenotypic diversity显示文摘Hepatocellular carcinoma(HCC) is the 3^(rd) leading cause of cancer-related death worldwide. More than 80% of HCCs arise within chronic liver disease resulting from viral hepatitis, alcohol, hemochromatosis, obesity and metabolic syndrome or genotoxins. Projections based on Western lifestyle and its metabolic consequences anticipate a further increase in incidence, despite recent breakthroughs in the management of viral hepatitis. HCCs display high heterogeneity of molecular phenotypes, which challenges clinical management. However, emerging molecular classifications of HCCs have not yet formed a unified corpus translatable to the clinical practice. Thus, patient management is currently based upon tumor number, size, vascular invasion, performance status and functional liver reserve. Nonetheless, an impressive body of molecular evidence emerged within the last 20 years and is becoming increasingly available to medical practitioners and researchers in the form of repositories. Therefore, the aim this work is to review molecular data underlying HCC classifications and to organize this corpus into the major dimensions explaining HCC phenotypic diversity. Major efforts have been recently made worldwide toward a unifying 'clinically-friendly' molecular landscape. As a result, a consensus emerges on three major dimensions explaining the HCC heterogeneity. In the first dimension, tumor cell proliferation and differentiation enabled allocation of HCCs to two major classes presenting profoundly different clinical aggressiveness. In the second dimension, HCC microenvironment and tumor immunity underlie recent therapeutic breakthroughs prolonging patients' survival. In the third dimension,metabolic reprogramming, with the recent emergence of subclass-specific metabolic profiles, may lead to adaptive and combined therapeutic approaches. Therefore, here we review recent molecular evidence, their impact on tumor histopathological features and clinical behavior and highlight the remaining challenges to translate our cognitive corpus into patient diagnosis and allocation to therapeutic options.Romain Désert Natalia Nieto Orlando Musso 2018World Journal of Gastroenterology2018,24,40:3
7湿物性对竹原纤维建筑填充材热工性能的影响显示文摘为探索作为建筑填充材的竹原纤维(BF)热湿物理性质及其相互作用规律,采用平衡含水率u值测试、吸放湿速率U值测试和导热系数λ值测试,以及蓄热系数S值和热惰性指标D值的推算,进行了竹原纤维热湿关联性研究.结果表明:u,U和λ值与环境相对湿度φ值之间存在指数函数关系,可以采用Y=a·e^(b·φ)+c的一般方程进行描述;在测试范围内BF的等温吸放湿u-φ曲线在φ为85.4%~96.3%阶段、吸放湿速率U-φ曲线在φ为75%~95%阶段快速增大;填充密度ρ为70~170kg/m^3的BF干燥λ值为0.042 3~0.046 5W/(m·K),潮湿λ值随环境相对湿度φ值的提高而显著增大,且增大速率与其自身填充密度呈正相关关系;增大u值和减小U值均有利于改善BF的热工性能,具体表现在增大u值可提高BF的S值和D值,而减小U值可大幅提高BF的热工稳定性.黄祖坚 孙一民 MUSSO Florian 2018建筑材料学报2018,21,2:3
8Brainstem–vermis and brainstem–tentorium angles allow accurate categorization of fetal upward rotation of cerebellar vermis显示文摘P.Volpe E.Contro F.De Musso T.Ghi A.Farina A.Tempesta G.Volpe N.Rizzo G.Pilu 2012Ultrasound Obstet Gynecol2012,,6:2
9Normal morphometry of fetal posterior fossa at midtrimester: brainstem–tentorium angle and brainstem–vermis angle显示文摘TullioGhi ElenaContro FrancescaDe Musso AntonioFarina RobertoConturso PaolaBonasoni GinevraSalsi AlyYoussef NicolaRizzo GianluigiPilu 2012Prenat Diagn2012,,5:2
10Is Renal Warm Ischemia over 30 Minutes during Laparoscopic Partial Nephrectomy Possible? One-Year Results of a Prospective Study显示文摘Francesco Porpiglia Julien Renard Michele Billia Francesca Musso Alessandro Volpe Rodolfo Burruni Carlo Terrone Loredana Colla Giorgina Piccoli Valerio Podio Roberto Mario Scarpa 2007European Urology2007,,4:2
11Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis显示文摘Giovanni Musso Roberto Gambino Maurizio Cassader 2012Progress in Lipid Research2012,,:2
12Zika virus: following the path of dengue and chikungunya?显示文摘Didier Musso Van Mai Cao-Lormeau Duane J Gubler 2015The Lancet . 2015 (9990)2015,,:2
13Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis显示文摘Giovanni Musso Roberto Gambino Franco De Michieli Maurizio Cassader Mario Rizzetto Marilena Durazzo Emanuela Fagà Barbara Silli Gianfranco Pagano 2003Hepatology2003,,4:2
14MMP-2 activation by collagen Ⅰ and concanavalin A in cultured human hepatic stellate cells显示文摘Theret N Lehti K Musso O 0,,:2
15A novel approach to control hyperglycemia in type 2 diabetes: Sodium glucose co-transport (SGLT) inhibitors. Systematic review and meta-analysis of randomized trials显示文摘Giovanni Musso Roberto Gambino Maurizio Cassader Gianfranco Pagano 2012Annals of Medicine2012,,4:2
16Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials显示文摘G. Musso M. Cassader F. Rosina R. Gambino 2012Diabetologia2012,,4:2
17Targeting the NF-kappaB pathway through pharmacological inhibition of IKK2 prevents human cytomegalovirus replication and virus-induced inflammatory response in infected endothelial cells 显示文摘Caposio P Musso T Luganini A 2007Antiviral Res2007,73,3:1
18Crohn's disease complicated by relapsed extranodal Hodgkin's lymphoma: prolonged eom- plete remission after unnlanlpulated PBPC autotransplant显示文摘Musso M Porrelto F Crescimanno A 2000Bone Marrow Transplant2000,26,:1
19Tumor progression is associated with a significant decrease in the expression of the endostatin precursor collagen ⅩⅧ in human hepatocellular carcinomas 显示文摘Musso O Rehn M Theret N 2001Cancer Res2001,61,1:1
20Training induced brain plasticity显示文摘Musso M Weiller C Kiebel S 1999Brain1999,122,9:1
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