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| 1 | 青藏高原羌塘中部蓝片岩的地球化学特征及其构造意义显示文摘青藏高原羌塘中部的冈玛日 -桃形错地区蓝片岩被认为是板块构造边界的产物 ,通过对其主量元素、微量元素和稀土元素的地球化学特征的综合研究 ,其原岩属于洋岛型碱性玄武岩。再结合该地区的地质研究 ,表明在该地区存在一个古特提斯洋 。 | 邓希光 丁林 刘小汉 An Yin Paul A KAPP Michael A MURPHY Craig E MANNING | 2002 | 岩石学报2002，18，4： | 58 |
| 2 | 簇毛麦对不同白粉病菌菌系的抗性反应及其在小麦遗传背景下的表达显示文摘对引自原苏联的簇毛麦(HaynaldiavilosaL.Schur2n=14VV)及其与硬粒小麦杂交育成的双二倍体TH1TH1WTH2WTH3TH3W,普通小麦-簇毛麦6D/6V异代换系及普通小麦亲本和已知抗白粉病基因的18个小麦品种为供试材料,用84个来自美国、德国、中国的小麦白粉病菌菌系进行苗期接种鉴定。发现簇毛麦及其衍生系对所有参试的白粉病菌系表现免疫和抗,比供试的已知抗性基因的18个小麦品种抗性强,抗谱广。其抗性基因在81086A、D311、墨75、陕7859、宛7107、冀麦30等小麦遗传背景下均能很好表达。 | 陈孝 施爱农 尚立民 Leath Steven Murphy J Paul | 1997 | 植物病理学报1997，27，1： | 34 |
| 3 | 西藏及其周围地区地壳、地幔地震层析成像——印度板块大规模俯冲于西藏高原之下的证据显示文摘文中介绍有关西藏—喜马拉雅碰撞带的一项地震层析成像研究。根据一个用天然地震数据产生的全球波速模型 ,印度板块有可能以近水平状俯冲于整个西藏高原之下至 16 5~ 2 6 0km深度。西藏岩石圈具有低波速地壳和高波速下岩石圈 (75~ 12 0km深 )。在 12 0~ 16 5km深度范围 ,西藏岩石圈与俯冲的印度板块之间有一层低速软流圈物质。高原中部从地表到 310km深处有一低速体 ,说明地幔物质有可能穿过俯冲板块的脆弱部位上隆。这些结果以及野外实测的地壳缩短值说明高原的抬升得助于印度板块的近水平俯冲。我们推论俯冲印度板块的升温上浮以及上覆软流层的存在是造成西藏高原高海拔抬升以及内部地表仍相对平坦的主要原因。2 0 0 1年 1月 2 6日在印度西部发生的毁灭性大地震有可能是俯冲应力在印度板块后缘薄弱处引发的岩石圈大断裂。 | 周华伟 Michael A. MURPHY 林清良 | 2002 | 地学前缘2002，9，4： | 32 |
| 4 | Seven Things We Think We Know about Auxin Transport显示文摘植物激素植物生长素的极的运输和最大值调整的局部性的植物生长素的建立胚胎的开发,干细胞维护,根和射击建筑学,和回归线生长回答。过去的十年被戏剧的进步在阐明的努力标记植物生长素运输由调整的复杂机制种生长。作为植物生长素的理解,运输规定逐渐地被详细描述,这个过程在某些方面涉及几乎所有植物生长和环境回答,变得清楚。然而,我们仍然关于这基本规章的机制的一些基本方面缺乏信息。在这评论,我们在场我们知道什么(或我们认为什么我们知道) 并且我们什么不知道大约七个调整植物生长素的过程。我们在主要、侧面的根,向光性,分叉的射击,叶扩大,和脉络在 gravitropism 讨论植物生长素运输的角色。我们也在根尖端,植物生长素运输过程的 flavonoid 调整,和植物生长素 transporters 的 translational 以后规定的突出的方面讨论植物生长素倒流 / 喷泉模型。这讨论没打算彻底,但是加亮在哪个通常认为假设要求更真实的确认的区域。 | Wendy Ann Peer Joshua J. Blakeslee Haibing Yang Angus S. Murphy | 2011 | Molecular Plant2011，4，3： | 29 |
| 5 | 成人、儿童及孕妇特发性血小板减少性紫癜诊治指南显示文摘特发性血小板减少性紫癜(ITP)是一种自体免疫性疾病,以持续性血小板减少为特征(血小板<150×109/L).其发病机理是自身抗体与血小板抗原结合导致它们在未成熟时即被网状内皮系统,特别是在脾脏中被破坏引起血小板减少. | Provan D Newland A Norfolk D Bolton-Maggs P Lilleyman J Greer I May A Murphy M Ouwehand W Watson S 李振宇 徐开林 | 2004 | 国外医学(输血及血液学分册)2004，27，4： | 25 |
| 6 | 考虑电极烧蚀影响的低压断路器电弧运动特性仿真及实验显示文摘以磁流体动力学(magnetic hydro-dynamics,MHD)为基础建立了考虑电极烧蚀影响的低压断路器中电弧的数学模型。在传统的质量、动量和能量守恒方程的基础上增加了铜蒸气的浓度方程,考虑电极烧蚀对气体的热动力学特性和传输系数的影响,针对阴极和阳极不同特点分别建立了电弧与阴极和阳极作用的数学模型。利用基于有限容积法的商业软件对上述模型进行求解,得出灭弧室内温度场、浓度场、气流场、电位场的分布情况。仿真结果表明,由于电极附近'双漩涡'的存在,使得Cu蒸气浓度最大的区域位于弧根后方靠近电极的区域;考虑Cu蒸气影响时计算得到的电弧电压为比未考虑Cu蒸气影响时减小12.3%;考虑Cu蒸气影响所得到的电弧平均运动速度比未考虑Cu蒸气影响时减少21.3%。实验结果验证了仿真模型的合理性。 | 马强 荣命哲 Anthony B. Murphy 吴翊 徐铁军 孙志强 | 2009 | 中国电机工程学报2009，29，3： | 19 |
| 7 | Wolbachia pipientis wMel基因组水平上的密码子使用分析显示文摘本实验检测了黑腹果蝇的专性寄生菌Wolbachia pipientis wMel基因组的密码子使用模式,并推测影响其密码子组成的因素.选择了478条蛋白编码基因作为研究对象,它们的GC含量比较低,约0.282~0.432.本研究结果显示,关联突变(context-dependent mutation)是影响W.pipientis wMel基因组密码子组成的主要因素.同时,Nc—Plot曲线显示,基因组的密码子组成还受到了核苷酸组成偏好性(nucleotide composition bias)的影响.对应分析的结果显示,基因长度(R=0.123,P〈0.01)和基因表达水平(R=-0.312,P〈0.01)也对基因组的密码子使用偏好性起到了一定的作用.因此,关联突变、核苷酸组成、基因长度和基因表达水平都会影响到基因组的密码子使用偏好性.Wolbachia基因组的几个特征和动物线粒体基因组具有较高的相似性,而且现在已有报道说明它们有共同的起源,但仍需进一步验证. | 孙铮 马亮 MURPHY Robert 张宪省 黄大卫 | 2009 | 中国科学(C辑)2009，39，10： | 17 |
| 8 | An Arabidopsis ABC Transporter Mediates Phosphate Deficiency-Induced Remodeling of Root Architecture by Modulating Iron Homeostasis in Roots显示文摘改变根建筑学是到磷酸盐(Pi ) 的植物的主要发展回答缺乏并且被认为在表层土为可得到的 Pi 提高一个植物能力到牧草。然而,控制这回答的内在的机制糟糕被理解。在这研究,我们识别了 Arabidopsis 异种, hps10 (对 Pi 饥饿 10 过分敏感) ,它在 Pi 足够的状况下面是词法上正常的,但是在 Pi 下面显示出主要的根生长和侧面的根的提高的生产的增加的抑制缺乏。hps10 是 ALUMINUM SENSITIVE3 (ALS3 ) 基因的以前识别的等位基因(als3-3 ) ,它涉及植物忍耐到铝毒性。我们的结果证明 ALS3 和它的交往的蛋白质 AtSTAR1 在 tonoplast 形成 ABC transporter 建筑群。这蛋白质建筑群调停一高度在 Xenopus 卵母细胞的 electrogenic 运输。在 Pi 缺乏下面, als3 比野类型在它的根积累 Fe 3+ 的高水平。在 Arabidopsis, LPR1 (低磷酸盐 ROOT1 ) 和 LPR2 编码 ferroxidases,当变异时,它在根和原因根生长减少 Fe 3+ 累积对 Pi 缺乏感觉迟钝。这里,我们提供证明 ALS3 与 LPR1/2 合作调整 Pi 的引人注目的证据在根的由 modulating Fe 动态平衡的根建筑学的导致缺乏的改变。 | Jinsong Dong Miguel A. PiSeros Xiaoxuan Li Haibing Yang Yu Liu Angus S. Murphy Leon V. Kochian Dong Liu | 2017 | Molecular Plant2017，10，2： | 13 |
| 9 | Perfluorooctane sulfonate(PFOS) and related fluorochemicals in chicken egg in China显示文摘The ubiquitous occurrence of perfluorinated compounds(PFCs) in environmental samples has drawn much attention.Recent human exposure studies found relatively high perfluorooctane sulfonate(PFOS) concentrations in blood samples from several cities in China when compared with other countries.The objectives of the present study were:(1) to measure PFC concentrations and compositions in chicken egg samples from local markets in China;and(2) to conduct a preliminary human health risk assessment of egg consumption.Eight pooled egg samples from eight locations were analyzed for 11 PFCs.The results showed that close to 100% of the PFOS in the egg was distributed in egg yolk and PFOS was not detected in egg white(<0.08 ng/g wet weight,w/w).Of the perfluoroalkylsulfonates,only PFOS was detected in all egg samples,while of the perfluoroalkylcarboxylates,perfluoroundecanoic acid(PFUnDA) was detected in all samples,followed by perfluorooctanoate(PFOA)(75% occurrence) and perfluorodecanoic acid(PFDA)(50% occurrence).PFOS concentrations in egg ranged from 45.0 to 86.9 ng/g w/w.The results suggested that current concentrations of PFOS in domestic chicken eggs are unlikely to cause immediate harm to Chinese populations. | WANG Yuan YEUNG Leo Wai Yin YAMASHITA Nobuyoshi TANIYASU Sachi SO Man Ka Margaret B. MURPHY LAM Paul Kwan Sing | 2008 | Chinese Science Bulletin2008，53，4： | 13 |
| 10 | 亚洲近视管理共识显示文摘指南的目标本指南是从国际近视研究所(IMI)白皮书中提取出来的有关近视管理方面的建议[1,2]。本指南所提供的内容都是根据现有最新数据(截至2022年3月)而来,其治疗可行性和执业范围因地区而异,应根据实际情况做调整。眼保健专家组通过对现有最优科学数据进行分析诠释,从而形成了本指南。在工作中,近视管理从业者应该将患者需求放在首位,全面考虑患者具体情况后再提出合适的处理意见。 | Monica Jong Serge Resnikoff Kah Ooi Tan 吕帆 Kah Meng Chung 胡楚南 Ian Morgan Oliver Kam Tong Woo 蓝卫忠 齐备 瞿佳 杨智宽 樊志诚 吴佩昌 Ian Flitcroft Murphy Hian Kee Chan Thok Chuan Tan Charlie Ho David Chai Wong Chong Liang Hwee Koh Olivia Qian Ru Cheng | 2022 | 中华眼视光学与视觉科学杂志2022，24，3： | 11 |
| 11 | Red River barrier and Pleistocene climatic fluctuations shaped the genetic structure of Microhyla fissipes complex (Anura: Microhylidae) in southern China and Indochina显示文摘 | Zhi-Yong YUAN Chatmongkon SUWANNAPOOM Fang YAN Nikolay A. POYARKOV JR Sang Ngoc NGUYEN Hong-man CHEN Siriwadee CHOMDEJ Robert W, MURPHY Jing CHE | 2016 | Current Zoology2016，62，6： | 11 |
| 12 | Speculations on the mechanisms for the formation and breakup of supercontinents显示文摘supercontinent 周期后来在地球的进化上有深刻效果晚太古代但是我们为它的操作负责的力量的理解留下逃犯。Supercontinents 由二个结束成员过程出现到形式:外翻,包围 supercontinent (外面的海洋) 的海洋的岩石圈在是优先地 subducted (例如 Pannotia ) ,并且海洋的岩石圈在驱散以前的 supercontinent (内部海洋) 的碎片之间在形成了的内向是优先地 subducted (例如 Pangea ) 。外翻能被 topdown 地球动力学, supercontinent 高在大地水准面上在拆散并且在大地水准面上面混合解释低。在另一方面,内向要求平板拉和山脉的联合力量推(它在 supercontinent 分散以后在音乐会操作) 必须被克服以便使以前分散的大陆能变得里面。当 subduction 地区沿着在内部、外面的海洋之间的边界被开始并且变得在内部海洋以内套住时,内向可以开始。我们推测在大陆人运动的颠倒为内向要求了,这可以被从核心披风边界触发 superplumes 的上升的平板雪崩事件导致。 | J.Brendan Murphy R.Damian Nance | 2013 | Geoscience Frontiers2013，4，2： | 10 |
| 13 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 14 | 我国老年人的社会支持与服务显示文摘鉴于我国老龄化现状,简要地回顾了社会支持的定义与种类,考察了我国传统的孝顺价值观和行为;并着重分析了我国老年人的社会支持与服务,包括老年人的社会支持与幸福感,老年人的家庭支持与照料,老年组织与公共老年服务;以及我国老年人社会支持的城乡差异。 | 严建雯 陈传锋 Mike Murphy | 2005 | 心理科学2005，28，6： | 9 |
| 15 | CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment显示文摘 | Andy Trotti A.Dimitrios Colevas Ann Setser Valerie Rusch David Jaques Volker Budach Corey Langer Barbara Murphy Richard Cumberlin C.Norman Coleman Philip Rubin | 2003 | Seminars in Radiation Oncology2003，，3： | 8 |
| 16 | Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a^(-/-) mice显示文摘AIM: To investigate the ability of a Prunella vulgaris(P. vulgaris) ethanolic extract to attenuate spontaneous typhlocolitis in mdr1a-/- mice. METHODS: Vehicle(5% ethanol) or P. vulgaris ethanolic extract(2.4 mg/d) were administered daily by oral gavage to mdr1a-/- or wild type FVBWT mice from 6 wk of age up to 20 wk of age. Clinical signs of disease were noted by monitoring weight loss. Mice experiencingweight loss in excess of 15% were removed from the study. At the time mice were removed from the study, blood and colon tissue were collected for analyses that included histological evaluation of lesions, inflammatory cytokine levels, and myeloperoxidase activity. RESULTS: Administration of P. vulgaris extracts to mdr1a-/- mice delayed onset of colitis and reduced severity of mucosal inflammation when compared to vehicle-treated mdr1a-/- mice. Oral administration of the P. vulgaris extract resulted in reduced(P < 0.05) serum levels of IL-10(4.6 ± 2 vs 19.4 ± 4), CXCL9(1319.0 ± 277 vs 3901.0 ± 858), and TNFα(9.9 ± 3 vs 14.8 ± 1) as well as reduced gene expression by more than two-fold for Ccl2, Ccl20, Cxcl1, Cxcl9, IL-1 α, Mmp10, VCAM-1, ICAM, IL-2, and TNFα in the colonic mucosa of mdr1a-/- mice compared to vehicle-treated mdr1a-/-mice. Histologically, several microscopic parameters were reduced(P < 0.05) in P. vulgaris-treated mdr1a-/-mice, as was myeloperoxidase activity in the colon(2.49 ± 0.16 vs 3.36 ± 0.06, P < 0.05). The numbers of CD4+ T cells(2031.9 ± 412.1 vs 5054.5 ± 809.5) and germinal center B cells(2749.6 ± 473.7 vs 4934.0 ± 645.9) observed in the cecal tonsils of P. vulgaris-treated mdr1a-/- were significantly reduced(P < 0.05) from vehicle-treated mdr1a-/- mice. Vehicle-treated mdr1a-/- mice were found to produce serum antibodies to antigens derived from members of the intestinal microbiota, indicative of severe colitis and a loss of adaptive tolerance to the members of the microbiota. These serum antibodies were greatly reduced or absent in P. vulgaris-treated mdr1a-/- mice. CONCLUSION: The anti-inflammatory activity of P. vulgaris ethanolic extract effectively attenuated the severity of intestinal inflammation in mdr1a-/- mice. | Kelley MK Haarberg Meghan J Wymore Brand Anne-Marie C Overstreet Catherine C Hauck Patricia A Murphy Jesse M Hostetter Amanda E Ramer-Tait Michael J Wannemuehler | 2015 | World Journal of Gastrointestinal Pharmacology and Therapeutics2015，6，4： | 8 |
| 17 | 簇毛麦抗白粉病基因的RAPD及RFLP标记显示文摘分析了来自前苏联簇毛麦及其抗病衍生系的抗白粉病基因对不同生理小种的抗性反应。用 120 个随机引物对 6D/6V 代换系 Pm930640 进行 RAPD 分析,检测到 5 个引物 OPAN03、OPAI01、OPAL03、OPAD07 和 OPAG15,分别在大约 1 700、700、750、480 和 580 bp 处有区别于小麦亲本的多态性条带。对 Chancellor×Pm930640 F2群体进行 OPAN03、OPAI01 和 OPAL03 等 3 个 RAPD 标记与抗白粉病基因的连锁分析,表明这些标记同簇毛麦的抗白粉病基因是连锁的。对大部分分别含有 Pm1-Pm20 的已知抗病基因、含有簇毛麦抗病基因及其相关亲本的 29 个小麦品系进行RAPD标记分析。结果表明,这些标记不仅可以鉴定簇毛麦的抗病基因,而且可以判断其遗传背景。OPAL03750仅出现在含有前苏联簇毛麦 6VS 染色体的抗病材料中,可作为区别于 Pm21 的分子标记。RFLP 标记的结果也表明两个不同簇毛麦的 6VS 染色体有明显的多态性。 | 李辉 陈孝 施爱农 孔凡晶 Leath S Murphy J P 贾旭 | 2005 | 中国农业科学2005，38，3： | 7 |
| 18 | Uterine receptivity and the plasma membrane transformation显示文摘This review begins with a brief commentary on the diversity of placentation mechanisms, and then goes on to examine the extensive alterations which occur in the plasma membrane of uterine epithelial cells during early pregnancy across species. Ultrastructural, biochemical and more general morphological data reveal that strikingly common phenomena occur in this plasma membrane during early pregnancy despite the diversity of placental types-from epitheliochorial to hemochorial, which ultimately form in different species. To encapsulate the concept that common morphological and molecular alterations occur across species, that they are found basolaterally as well as apically, and that moreover they are an ongoing process during much of early pregnancy, not just an event at the time attachment,brane during early pregnancy are key to uterine receptivity. | Christopher R MURPHY | 2004 | Cell Research2004，14，4： | 7 |
| 19 | 加拿大不列颠哥伦比亚省精神卫生法简介显示文摘本文简要介绍加拿大不列颠哥伦比亚 ( BC) | 王小平 Murphy Emlene | 2004 | 国外医学(精神病学分册)2004，31，3： | 6 |
| 20 | Analysis of the current rib support practices and techniques in U.S. coal mines显示文摘Design of rib support systems in U.S. coal mines is based primarily on local practices and experience. A better understanding of current rib support practices in U.S. coal mines is crucial for developing a sound engineering rib support design tool. The objective of this paper is to analyze the current practices of rib control in U.S. coal mines. Twenty underground coal mines were studied representing various coal basins,coal seams,geology,loading conditions,and rib control strategies. The key findings are:(1) any rib design guideline or tool should take into account external rib support as well as internal bolting;(2) rib bolts on their own cannot contain rib spall,especially in soft ribs subjected to significant load—external rib control devices such as mesh are required in such cases to contain rib sloughing;(3) the majority of the studied mines follow the overburden depth and entry height thresholds recommended by the Program Information Bulletin 11-29 issued by the Mine Safety and Health Administration;(4) potential rib instability occurred when certain geological features prevailed—these include draw slate and/or bone coal near the rib/roof line,claystone partings,and soft coal bench overlain by rock strata;(5) 47% of the studied rib spall was classified as blocky—this could indicate a high potential of rib hazards; and(6) rib injury rates of the studied mines for the last three years emphasize the need for more rib control management for mines operating at overburden depths between 152.4 m and 304.8 m. | Mohamed Khaled M. Murphy Michael M. Lawson Heather E. Klemetti Ted | 2016 | International Journal of Mining Science and Technology2016，26，1： | 6 |
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