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1Roux-en-Y versus BillrothⅠreconstruction after distal gastrectomy for gastric cancer:A meta-analysis显示文摘AIM:To conduct a meta-analysis to compare Rouxen-Y(R-Y) gastrojejunostomy with gastroduodenal Billroth Ⅰ(B-Ⅰ) anastomosis after distal gastrectomy(DG) for gastric cancer.METHODS:A literature search was performed to identify studies comparing R-Y with B-Ⅰ after DG for gastric cancer from January 1990 to November 2012 in Medline,Embase,Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in The Cochrane Library.Pooled odds ratios(OR) or weighted mean differences(WMD) with 95%CI were calculated using either fixed or random effects model.Operative outcomes such as operation time,intraoperative blood loss and postoperative outcomes such as anastomotic leakage and stricture,bile reflux,remnant gastritis,reflux esophagitis,dumping symptoms,delayed gastric emptying and hospital stay were the main outcomes assessed.Meta-analyses were performed using RevMan 5.0 software(Cochrane library).RESULTS:Four randomized controlled trials(RCTs) and 9 non-randomized observational clinical studies(OCS) involving 478 and 1402 patients respectively were included.Meta-analysis of RCTs revealed that R-Y reconstruction was associated with a reduced bile reflux(OR 0.04,95%CI:0.01,0.14;P < 0.00 001) and remnant gastritis(OR 0.43,95%CI:0.28,0.66;P = 0.0001),however needing a longer operation time(WMD 40.02,95%CI:13.93,66.11;P = 0.003).Metaanalysis of OCS also revealed R-Y reconstruction had a lower incidence of bile reflux(OR 0.21,95%CI:0.08,0.54;P = 0.001),remnant gastritis(OR 0.18,95%CI:0.11,0.29;P < 0.00 001) and reflux esophagitis(OR 0.48,95%CI:0.26,0.89;P = 0.02).However,this reconstruction method was found to be associated with a longer operation time(WMD 31.30,95%CI:12.99,49.60;P = 0.0008).CONCLUSION:This systematic review point towards some clinical advantages that are rendered by R-Y compared to B-Ⅰ reconstruction post DG.However there is a need for further adequately powered,welldesigned RCTs comparing the same.Jun-Jie Xiong Kiran Altaf Muhammad A Javed Quentin M Nunes Wei Huang Gang Mai Chun-Lu Tan Rajarshi Mukherjee Robert Sutton Wei-Ming Hu Xu-Bao Liu 2013World Journal of Gastroenterology2013,19,7:33
2Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma显示文摘AIM:To conduct a meta-analysis to determine the safety and efficacy of laparoscopic liver resection(LLR) and open liver resection(OLR) for hepatocellular carcinoma(HCC).METHODS:PubMed(Medline),EMBASE and Science Citation Index Expanded and Cochrane Central Register of Controlled Trials in the Cochrane Library were searched systematically to identify relevant comparative studies reporting outcomes for both LLR and OLR for HCC between January 1992 and February 2012.Two authors independently assessed the trials for inclusion and extracted the data.Meta-analysis was performed using Review Manager Version 5.0 software(The Cochrane Collaboration,Oxford,United Kingdom).Pooled odds ratios(OR) or weighted mean differences(WMD) with 95%CI were calculated using either fixed effects(Mantel-Haenszel method) or random effects models(DerSimonian and Laird method).Evaluated endpoints were operative outcomes(operation time,intraoperative blood loss,blood transfusion requirement),postoperative outcomes(liver failure,cirrhotic decompensation/ascites,bile leakage,postoperative bleeding,pulmonary complications,intraabdominal abscess,mortality,hospital stay and oncologic outcomes(positive resection margins and tumor recurrence).RESULTS:Fifteen eligible non-randomized studies were identified,out of which,9 high-quality studies involving 550 patients were included,with 234 patients in the LLR group and 316 patients in the OLR group.LLR was associated with significantly lower intraoperative blood loss,based on six studies with 333 patients [WMD:-129.48 mL;95%CI:-224.76-(-34.21) mL;P = 0.008].Seven studies involving 416 patients were included to assess blood transfusion requirement between the two groups.The LLR group had lower blood transfusion requirement(OR:0.49;95%CI:0.26-0.91;P = 0.02).While analyzing hospital stay,six studies with 333 patients were included.Patients in the LLR group were found to have shorter hospital stay [WMD:-3.19 d;95%CI:-4.09-(-2.28) d;P < 0.00001] than their OLR counterpart.Seven studies including 416 patients were pooled together to estimate the odds of developing postoperative ascites in the patient groups.The LLR group appeared to have a lower incidence of postoperative ascites(OR:0.32;95%CI:0.16-0.61;P = 0.0006) as compared with OLR patients.Similarly,fewer patients had liver failure in the LLR group than in the OLR group(OR:0.15;95%CI:0.02-0.95;P =0.04).However,no significant differences were found between the two approaches with regards to operation time [WMD:4.69 min;95%CI:-22.62-32 min;P = 0.74],bile leakage(OR:0.55;95%CI:0.10-3.12;P = 0.50),postoperative bleeding(OR:0.54;95%CI:0.20-1.45;P = 0.22),pulmonary complications(OR:0.43;95%CI:0.18-1.04;P = 0.06),intra-abdominal abscesses(OR:0.21;95%CI:0.01-4.53;P = 0.32),mortality(OR:0.46;95%CI:0.14-1.51;P = 0.20),presence of positive resection margins(OR:0.59;95%CI:0.21-1.62;P = 0.31) and tumor recurrence(OR:0.95;95%CI:0.62-1.46;P = 0.81).CONCLUSION:LLR appears to be a safe and feasible option for resection of HCC in selected patients based on current evidence.However,further appropriately designed randomized controlled trials should be undertaken to ascertain these findings.Jun-Jie Xiong Kiran Altaf Muhammad A Javed Wei Huang Rajarshi Mukherjee Gang Mai Robert Sutton Xu-Bao Liu Wei-Ming Hu 2012World Journal of Gastroenterology2012,18,45:25
3Continuous quality and shelf life monitoring of retail-packed fresh cod loins in comparison with conventional methods显示文摘Nga T.T. Mai María Gudjónsdóttir Hélène L. Lauzon Kolbrún Sveinsdóttir Emilía Martinsdóttir Hubert Audorff Werner Reichstein Dietrich Haarer Sigurdur G. Bogason Sigurjón Arason 2010Food Control2010,,6:2
4Chemo-enzymatic synthesis and characterization of graft copolymers from lignin and acrylic compounds显示文摘 Majcherczyk A Huttermann A 2000Enzyme and Microbial Technology2000,27,:1
5Tertiary treatment of wastewater from a cosmetic industry using reed beds显示文摘Koukios M Vlyssides A Mai S 2004protection and Restoration of the Environment2004,,6:1
6Characterisation of dissimilar joints in laser welding of steel-kovar,copper-steel and copper-aluminum显示文摘Mai T A Spowage A C 0,,:1
7A feedback approach to the steady-state performance of fractionally fractionally spaced blind ada- ptive equalizers显示文摘J Mai A H Sayed 2000IEEE Transactions on Signal Process- ing2000,48,1:1
8Debugging the data plane with anteater显示文摘Mai H Khurshid A Agarwal R 2011ACM SIGCOMM Computer Communication Review2011,41,4:1
9Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans 显示文摘MAI A ROTILI D MASSA S 2007Bioorganic & Medicinal Chemistry Letters2007,17,:1
10Major and trace elements of selected pedons in the USA显示文摘Burt R Wilson M A Mays M D S 2003Journal of Environmental Quality2003,32,:1
11Reestablishing occlusal vertical dimension using a diagnostic treatment prosthesis in the edentulous patient: a clinicalreport显示文摘Mays K A 2003J-Prosthodont2003,12,1:1
12Prenatal diagnosis and prognosis of a vein of Galen aneurysm assessed by pulse and color Doppler US显示文摘Mai R Rempen A 1996UOG1996,7,:1
13Modification of lignin for the production of new compounded materials显示文摘HüTTERMANN A MAI C KHARAZIPOUR A 2001Appl Microbiol Biotechnol2001,55,:1
14Dietary fiber and risk of colorectal cancer in the Breast Cancer Detection Demonstration Project (BCDDP) follow-up cohort显示文摘MAI V FLOOD A PETER U 2003Int J Epidemiol2003,32,:1
15Histone deaeetylation in epigenetics: an attractive target for anticancer therapy显示文摘MAI A MASSA S ROTILI D 2005Med Res Rev2005,25,3:1
16IL-35 is a novel responsive anti-in- flammatory eytokine--a new system of categorizing anti-inflammatory cytokines显示文摘Li X Mai J Virtue A 2012PLoS One2012,7,33:1
17Chemical vapour transport of pyrite (FeS2) with halogen (Cl,Br,I)显示文摘 Mai J Ennaoui A 1987Journal of Crystal Growth1987,78,3:1
18Overexpression of the wild type p73 gene in human bladder cancer显示文摘Yokomizo A Mai M Tindall DJ 1999Oncogene1999,18,8:1
19Comparison of heavy metal accumulation in a natural wetland and constructed wetlands receiving acid mine drainage显示文摘Mays P A Edwards G S 2001Ecological Engineering2001,16,:1
20Synthesis and biological evaluation of enantiomerically pure oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors 显示文摘Mai A Artico M Esposito M 2003Farmaco2003,58,3:1
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