|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Laparoscopic rectal cancer surgery: Where do we stand?显示文摘Large comparative studies and multiple prospective randomized control trials (RCTs) have reported equivalence in short and long-term outcomes between the open and laparoscopic approaches for the surgical treatment of colon cancer which has heralded widespread acceptance for laparoscopic resection of colon cancer. In contrast, laparoscopic total mesorectal excision (TME) for the treatment of rectal cancer has been welcomed with significantly less enthusiasm. While it is likely that patients with rectal cancer will experience the same benefits of early recovery and decreased postoperative pain from the laparoscopic approach, whether the same oncologic clearance, specifically an adequate TME can be obtained is of concern. The aim of the current study is to review the current level of evidence in the literature on laparoscopic rectal cancer surgery with regard to short-term and long-term oncologic outcomes. The data from 8 RCTs, 3 metaanalyses, and 2 Cochrane Database of Systematic Reviews was reviewed. Current data suggests that laparoscopic rectal cancer resection may benefit patients with reduced blood loss, earlier return of bowel function, and shorter hospital length of stay. Concerns that laparoscopic rectal cancer surgery compromises short-term oncologic outcomes including number of lymph nodes retrieved and circumferential resection margin and jeopardizes long-term oncologic outcomes has not conclusively been refuted by the available literature. Laparoscopic rectal cancer resection is feasible but whether or not it compromises short-term or long-term results still needs to be further studied. | Mukta K Krane Alessandro Fichera | 2012 | World Journal of Gastroenterology2012，18，46： | 11 |
| 2 | 3D integration review显示文摘3-D integration delivers value by increasing the volumetric transistor density with the potential benefit of shorter electrical path lengths through use of the shorter third dimension. Several researchers have studied various aspect of 3Di such as bonding level, through silicon via processes and integration, thermomechanical reliability of the vias, and the impact of the vias on devices. In this paper, we review some of the literature with a view to understanding the key options and challenges in 3Di. We also discuss some important applications of this technology, and the constraints that have to be overcome to make it work. | FAROOQ Mukta G. IYER Subramanian S. | 2011 | Science China(Information Sciences)2011，54，5： | 7 |
| 3 | Inflammatory bowel disease surgery in the biologic era显示文摘Anti-tumour necrosis factor(TNF)-α therapy has revolutionized inflammatory bowel disease(IBD) treatment. Infliximab and adalimumab either as monotherapy or in combination with an immunomodulator are able to induce clinical and biological remission in patients with moderate and severe Crohn's disease(CD) and ulcerative colitis(UC). These new therapies have led to a shift in the goals of IBD management from just controlling clinical symptoms to preventing disease progression. However, despite these advances in medical therapy, surgery is still required in 30%-40% of patients with CD and 20%-30% of patients with UC at some point during their lifetime. While biologics certainly play a major role in the medical treatment of IBD, there is concern about the effects of these anti-TNF-α agents on postoperative complications and morbidity. The purpose of this article is to review the role of surgery in the treatment of IBD in the age of biologics and the impact of these medications on per-operative outcomes. In this manuscript we review the relationship between biologic agents and surgery in the treatment of IBD. We also discuss in detail the periopetative risks and complications. | Linda Ferrari Mukta K Krane Alessandro Fichera | 2016 | World Journal of Gastrointestinal Surgery2016，8，5： | 4 |
| 4 | Cell-type specificity of β-actin expression and its clinicopathological correlation in gastric adenocarcinoma显示文摘AIM:To investigate cell type specific distribution ofβ-actin expression in gastric adenocarcinoma and its correlation with clinicopathological parameters.METHODS:β-actin is a housekeeping gene,frequently used as loading control,but,differentially expresses in cancer.In gastric cancer,an overall increased expression ofβ-actin has been reported using tissue disruptive techniques.At present,no histological data is available to indicate its cell type-specific expression and distribution pattern.In the present study,we analyzedβ-actin expression and distribution in paired normal and tumor tissue samples of gastric adenocarcinoma patients using immunohistochemistry(IHC),a tissue non-disruptive technique as well as tissue disruptive techniques like reverse transcriptase-polymerase chain reaction(RT-PCR)and western blotting.Correlation ofβ-actin level with clinicopathological parameters was done using univariate analysis.RESULTS:The results of this study showed significant overexpression,at both mRNA and protein level in tumor tissues as confirmed by RT-PCR(1.47±0.13 vs2.36±0.16;P<0.001)and western blotting(1.92±0.26 vs 2.88±0.32;P<0.01).IHC revealed thatβ-actin expression is majorly distributed between epithelial and inflammatory cells of the tissues.Inflammatory cells showed a significantly higher expression compared to epithelial cells in normal(2.46±0.13 vs 5.92±0.23,P<0.001),as well as,in tumor tissues(2.79±0.24 vs6.71±0.14,P<0.001).Further,comparison of immunostaining between normal and tumor tissues revealed that both epithelial and inflammatory cells overexpressβ-actin in tumor tissues,however,significant difference was observed only in inflammatory cells(5.92±0.23vs 6.71±0.14,P<0.01).Moreover,combined expression in epithelial and inflammatory cells also showed significant increase(4.19±0.15 vs 4.75±0.14,P<0.05)in tumor tissues.In addition,univariate analysis showed a positive correlation ofβ-actin level of inflammatory cells with tumor grade(P<0.05)while epithelial cells exhibited negative correlation(P>0.05).CONCLUSION:In gastric cancer,β-actin showed an overall higher expression predominantly contributed by inflammatory or tumor infiltrating immune cells of the tissue microenvironment and correlates with tumor grade. | Shafqat A Khan Monica Tyagi Ajit K Sharma Savio G Barreto Bhawna Sirohi Mukta Ramadwar Shailesh V Shrikhande Sanjay Gupta | 2014 | World Journal of Gastroenterology2014，20，34： | 2 |
| 5 | Comparison of EUS-guided rendezvous and precut papillotomy techniques for biliary access (with videos)显示文摘 | Vinay Dhir Suryaprakash Bhandari Mukta Bapat Amit Maydeo | 2012 | Gastrointestinal Endoscopy2012，，2： | 2 |
| 6 | Epitaxially grown zinc-blende structured Mn doped ZnO nanoshell on ZnS nanoparticles 显示文摘 | Mukta V Shashi B | 2009 | Mater Res Bull2009，44，： | 1 |
| 7 | En- hancing the hydrogen storage capacity of Pd-functionalized multi-walled carbon nanotubes显示文摘 | Priyanka Singh Mukta V Kulkarmi Suresh P Gokhale | 2012 | Appl Surf Sci2012，258，： | 1 |
| 8 | Anterior cervical reconstruction using titanium cage with anterior plating显示文摘 | Mohanmrnad E Maid Mukta Vadhva Richard T Holt | 1999 | Spine1999，24，： | 1 |
| 9 | Morphogenesis and plant regeneration from tissue cultures of Jatropha curcas显示文摘 | SUJATHA M MUKTA N | 1996 | Plant Cell Tiss Organ Cult1996，44，： | 1 |
| 10 | Pollen tube hehaviour and haploid wheat production via embryo rescue in wheatxmaize crosses显示文摘 | Vijaipal Khanna V K | 2003 | Indian Journal of Genetics and Plant Breeding2003，63，1： | 1 |
| 11 | Morphogenesis and plant regeneration from tissue cultures of Jatropha curcas显示文摘 | Sujatha M Mukta N | 1996 | Plant Cell Tissue and Organ Culture1996，44，2： | 1 |
| 12 | Increased frequency and noc-turia in a middle aged male may not always be due to benignprostatic hypertrophy: a case report显示文摘 | Kumar G Jamie F Mukta P | 2009 | Cases J2009，2，1： | 1 |
| 13 | Reduced-Intensity Allogeneic Transplant in Patients Older Than 55 Years: Unrelated Umbilical Cord Blood Is Safe and Effective for Patients without a Matched Related Donor显示文摘 | Navneet S. Majhail Claudio G. Brunstein Marcie Tomblyn Avis J. Thomas Jeffrey S. Miller Mukta Arora Dan S. Kaufman Linda J. Burns Arne Slungaard Philip B. McGlave John E. Wagner Daniel J. Weisdorf | 2008 | Biology of Blood and Marrow Transplantation2008，，3： | 1 |
| 14 | Management of edema in nephrotic syndrome显示文摘 | Anil V Mukta M Arvind B | 2004 | Indian Pediatr2004，41，： | 1 |
| 15 | Chronic Graft-Versus-Host Disease (cGVHD) following Unrelated Donor Hematopoietic Stem Cell Transplantation (HSCT): Higher Response Rate In Recipients of Unrelated Donor (URD) Umbilical Cord Blood (UCB)显示文摘 | Mukta Arora Sriharsha Nagaraj John E. Wagner Juliet N. Barker Claudio G. Brunstein Linda J. Burns Todd E. DeFor Margaret L. McMillan Jeffrey S. Miller Daniel J. Weisdorf | 2007 | Biology of Blood and Marrow Transplantation2007，，10： | 1 |
| 16 | Morphogenesis and plant regeneration from tissue cultures of Jatropha curcas显示文摘 | M. Sujatha N. Mukta | 1996 | Plant Cell Tissue and Organ Culture1996，，2： | 1 |
| 17 | Ibandronate显示文摘 | Mukta D Julia AB | 1999 | Drugs1999，57，1： | 1 |
| 18 | Neural networks and statistical techniques: a review of applications显示文摘 | Mukta Paliwal Kumar U A | 2009 | Expert Systems with Applications2009，36，1： | 1 |
| 19 | Morphogenesis and plant regeneration from tissue cultures of Jatropha curcas 显示文摘 | SUIATHA M MUKTA N | 1996 | Plant Cell Tissue and Organ Culture1996，44，2： | 1 |
| 20 | Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats显示文摘 | Suneela S. Dhaneshwar Mukta Chail Mahavir Patil Salma Naqvi Gaurav Vadnerkar | 2008 | European Journal of Medicinal Chemistry2008，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员