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| 1 | Novel non-invasive biological predictive index for liver fibrosis in hepatitis C virus genotype 4 patients显示文摘AIM To investigate the diagnostic ability of a non-invasive biological marker to predict liver fibrosis in hepatitis C genotype 4 patients with high accuracy.METHODS A cohort of 332 patients infected with hepatitis C genotype 4 was included in this cross-sectional study. Fasting plasma glucose, insulin, C-peptide, and angiotensinconverting enzyme serum levels were measured. Insulin resistance was mathematically calculated using the homeostasis model of insulin resistance(HOMA-IR).RESULTS Fibrosis stages were distributed based on Metavir score as follows: F0 = 43, F1 = 136, F2 = 64, F3 = 45 and F4 = 44. Statistical analysis relied upon reclassification of fibrosis stages into mild fibrosis(F0-F) = 179, moderate fibrosis(F2) = 64, and advanced fibrosis(F3-F4) = 89. Univariate analysis indicated that age, log aspartate amino transaminase, log HOMA-IR and log platelet count were independent predictors of liver fibrosis stage(P < 0.0001). A stepwise multivariate discriminant functional analysis was used to drive a discriminative model for liver fibrosis. Our index used cut-off values of ≥ 0.86 and ≤-0.31 to diagnose advanced and mild fibrosis, respectively, with receiving operating characteristics of 0.91 and 0.88, respectively. The sensitivity, specificity, positive predictive value, negative predictive value and positive likelihood ratio were: 73%, 91%, 75%, 90% and 8.0 respectively for advanced fibrosis, and 67%, 88%, 84%, 70% and 4.9, respectively, for mild fibrosis.CONCLUSION Our predictive model is easily available and reproducible, and predicted liver fibrosis with acceptable accuracy. | Mahmoud Khattab Mohamed Amin Sakr Mohamed Abdel Fattah Youssef Mousa Elwy Soliman Ashraf Breedy Mona Fathi Salwa Gaber Ahmed Altaweil Ashraf Osman Ahmed Hassouna Ibrahim Motawea | 2016 | World Journal of Hepatology2016，8，32： | 2 |
| 2 | The invasive phenotype of placenta accreta extravillous trophoblasts associates with loss of E-cadherin显示文摘 | Duzyj CM Buhimschi IA Motawea H | 2015 | Placenta2015，36，6： | 1 |
| 3 | Association of blunted nighttime blood pressure dipping with coronary artery stenosis in men显示文摘 | Tarek Mousa Moustafa A. El-Sayed Ahmed K. Motawea Mohsen A. Salama Abdou Elhendy | 2004 | American Journal of Hypertension2004，，10： | 1 |
| 4 | Thrombolysis for the management of massive pulmonary embolism in pregnancy显示文摘 | M.M. Tawfik M.E. Taman A.A. Motawea E. Abdel-Hady | 2013 | International Journal of Obstetric Anesthesia2013，，2： | 1 |
| 5 | The invasive phenotype of placenta accreta extravillous trophoblasts associates with loss of E-cadherin显示文摘 | Duzyji CM Buhimschi A Motawea H | 2015 | Placenta2015，，36： | 1 |
| 6 | Reverse of Left Ventricular Volumetric and Structural Remodeling in Heart Failure Patients Treated With Cardiac Resynchronization Therapy显示文摘 | Osama I.I. Soliman Marcel L. Geleijnse Dominic A.M.J. Theuns Attila Nemes Wim B. Vletter Bas M. van Dalen Ahmed K. Motawea Luc J. Jordaens Folkert J. ten Cate | 2008 | The American Journal of Cardiology2008，，5： | 1 |
| 7 | Thrombolysis for the management of massive pulmonary embolism in pregnancy显示文摘 | M.M. Tawfik M.E. Taman A.A. Motawea E. Abdel-Hady | 2013 | International Journal of Obstetric Anesthesia2013，，2： | 1 |
| 8 | Efficacy of Myrrh in the treatment of schistosomiasis (haematobium and mansoni) in Ezbet E1-Bakly, Tamyia Center, E1-Fayoum Governorate, Egypt 显示文摘 | Abo-Madyan AA Morsy TA Motawea SM | 2004 | J Egypt Soc Parasitol2004，34，2： | 1 |
| 9 | Atypical pathogens in community acquired pneumonia of Egyptian children显示文摘Objective:Diagnosis of atypical pathogens as an aetiology for community-acquired pneumonia(CAP) in children is a challenge world wide.The aim of this study was to detect the frequency of atypical pathogens as a cause of community-acquired pneumonia(CAP) in Egyptian children.Methods:From 50 children(with age ranged from 2 months to 12 years) hospitalized for community-acquired pneumonia;respiratory sputum samples were collected by induction or spontaneously.All samples were subjected to conventional cultures and Polymerase Chain Reaction(PCR) technique DNA extraction for identification of Mycoplasma,Chlamydia pneumoniae and Legionella pneumophila.Results;A definite pathogen was identified in 78%of the studied children;30% typical bacteria,8%Candida albicans and atypical bacteria in 40%of the pneumonic children.Chlamydia pneumoniae was isolated from 26%of the children while Mycoplasma pneumoniae was isolated from 14%, whereas Legionella pneumophilla was not isolated at all.Conclusion;Atypical pathogens are evident as a potential aetiology for community-acquired pneumonia in(13.3%) of young and(80%) of older Egyptian children. | Deraz TE El Sahriggy SA Shaheen MA Motawea AA Gomaa HE Fawzy SH Mohamed AA | 2009 | Asian Pacific Journal of Tropical Medicine2009，2，2： | 0 |
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