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| 1 | 氧化应激检测在男性不育临床中的应用显示文摘活性氧 (ROS)在低浓度发生可以调节正常精子功能 ,而高浓度ROS危害精子的存活力和功能。ROS产生过量与抗氧化系统损伤会发生氧化应激 (OS)。目前认为损伤OS促进了一系列男性生殖功能的病理学改变。ROS介导的精子质膜过氧化损伤 ,可以解释在高比例的不育病人中观察到的精子功能缺陷。ROS产生过多也会破坏精子核内DNA的完整性。DNA碱基对OS敏感 ,这些结构的过氧化能引起碱基修饰、DNA链断裂以及染色质交联。由过量ROS诱发的DNA损伤会加速生殖细胞凋亡过程 ,导致与男性不育相关的精子计数降低 ,以及可以解释近半个世纪以来所观察到的精液质量明显下降现象。近 10年来 ,克里夫兰临床基金会的研究组已经查明了男性不育中OS的关键作用 ;研究的主要目的是将这些重要的知识从实验室转向临床应用。我们设计的研究目标 :①理解精液中OS发生的精确机制 ;②建立准确评估OS状态的实验 ,并进行质控研究 ;③检测OS与精子核DNA损伤之间的相关性 ; | Ashok Agarwal Ramadan Abdou Saleh | 2002 | 中华男科学杂志2002，8，1： | 26 |
| 2 | Advances of injectable hydrogel-based scaffolds for cartilage regeneration显示文摘Articular cartilage is an important load-bearing tissue distributed on the surface of diarthrodial joints.Due to its avascular,aneural and non-lymphatic features,cartilage has limited self-regenerative properties.To date,the utilization of biomaterials to aid in cartilage regeneration,especially through the use of injectable scaffolds,has attracted considerable attention.Various materials,therapeutics and fabrication approaches have emerged with a focus on manipulating the cartilage microenvironment to induce the formation of cartilaginous structures that have similar properties to the native tissues.In particular,the design and fabrication of injectable hydrogel-based scaffolds have advanced in recent years with the aim of enhancing its therapeutic efficacy and improving its ease of administration.This review summarizes recent progress in these efforts,including the structural improvement of scaffolds,network cross-linking techniques and strategies for controlled release,which present new opportunities for the development of injectable scaffolds for cartilage regeneration. | Jiawei Li Guojun Chen Xingquan Xu Peter Abdou Qing Jiang Dongquan Shi Zhen Gu | 2019 | Regenerative Biomaterials2019，6，3： | 11 |
| 3 | Cu(Ⅱ),Ni(Ⅱ),Co(Ⅱ),Mn(Ⅱ),Zn(Ⅱ)和Cd(Ⅱ)的乙基3-(2-氨硫化亚肼基)-2-(羟胺基)丁烯酸酯配合物:合成、表征和细胞毒性(英文)显示文摘合成了Cu(Ⅱ),Ni(Ⅱ),Co(Ⅱ),Mn(Ⅱ),Zn(Ⅱ)和Cd(Ⅱ)的乙基3-(2-氨硫化亚肼基)-2-(羟胺基)丁烯酸酯配合物(H2L)并用元素分析,DTA热分析,IR,UV-Vis,1H-NMR,质谱,顺磁共振以及磁矩,电导率测量等对合成的配合物进行表征.摩尔电导率测量结果证明合成的配合物为非电解质.光谱数据表明配体分别表现为一元的三齿配体,一元的二齿配体,中性的二齿配体,中性的三齿配体,一元的四齿配体或二元的四齿配体通过席夫碱的氮原子,氨基硫脲中的氮原子,肟中的氮原子和硫酮中的硫原子与金属离子键合生成围绕金属离子的四面体或平面正方形构型.固态Cu(Ⅱ)(2),(3),(4)和(5)的配合物顺磁共振谱表明其为轴向对称,但(10~15)的配合物却为各向异性.配体和配合物(2),(3),(10),(13),(16)和(19)由于它们对乳腺癌(MCF-7细胞系)和肝癌(HePG-2细胞系)的抑制作用而表现出潜在的抗癌活性. | Ramadan M El Bahnasawy Abdou S El-Tabl Mohamad M E Shakdofa Noran M Abd El-Wahed | 2014 | 无机化学学报2014，30，6： | 4 |
| 4 | 5-Nitro-1,2,4-triazole-3-one:A Review of Recent Advances显示文摘The 3?Nitro?1,2,4?triazole?5?one(NTO)is a high energy density materials of keen interest for both commercial and scientific worlds owing to its reduced sensitivity,better thermal stability and high performances. It plays a significant role to replace the current energetic ingredients. In this review,we summarize various strategies involved in the synthesis of NTO as well as the existing approaches to tailor its particle morphology and sizes. The most prominent properties of NTO,such as insensitivity and performance,which are usually required to produce efficient formulations,have been concisely discussed. In addition,this overview reports on some newer forms of NTO including derivatives and co?crystals available in the literature,which can enhance the NTO features and extend its applications. The advantages and shortcomings of various NTO forms for specific and potential use are also highlighted together with the attempts made to overcome these issues. Therefore,efforts will certainly continue to improve characteristics and performances of NTO either by chemical modification or by co?crystallization in order to produce promising formulations for widespread applications in the near future. | Sabrina Hanafi Djalal Trache Slimane Abdous Zineddine Bensalem Abderrahmane Mezroua | 2019 | 含能材料2019，27，4： | 3 |
| 5 | 基于改进RRT算法的移动机器人路径规划方法显示文摘针对RRT(快速随机搜索树)算法在复杂环境下规划效率低,且规划的路径不平滑的问题,提出一种改进的RRT算法。首先引入一种全新的目标偏向采样策略,在均匀采样得到的随机点与目标点的连线上随机取一个点作为新的随机点进行树的扩展。其次对冗余路径节点进行剪枝处理,将路径起始节点与后续节点连线与障碍物进行碰撞检测,滤除无效的弯折路径。最后采用多项式插值的方法,依据节点的边界条件进一步对路径进行曲率平滑处理。通过仿真实验验证,论文算法不仅极大地提升了原算法的规划效率,而且在很大程度上优化了路径。 | 赵文龙 Abdou Yahouza M.Sani | 2022 | 计算机与数字工程2022，50，8： | 3 |
| 6 | Vitamin D status and viral response to therapy in hepatitis C infected children显示文摘AIM: To study the frequency of vitamin D deficiency in patients with hepatitis C virus(HCV) infection and to evaluate the role of vitamin D supplementation in improving antiviral therapy.METHODS: Sixty-six children aged from 7-14 years(mean ± SD, 11.17 ± 2.293) diagnosed with HCV infection were matched to 28 healthy controls. Serum levels of 25(OH) D3, calcium, phosphorus, alkaline phosphatase and plasma level of parathormone were measured. Quantitative PCR for HCV was performed Bone density was determined by dual energy X-ray absorptiometry. All cases received conventional therapy, and only 33 patients received vitamin D supplementation.RESULTS: Children with HCV showed significantly increased levels of HCV RNA(P < 0.001), parathormone(P < 0.01) and decreased vitamin D levels(P < 0.05)(33.3% deficient and 43.3% insufficient) compared with controls. Abnormal bone status(Z score-1.98 ± 0.75) was found in ribs, L-spine, pelvis and total body. Cases treated with vitamin D showed significant higher early(P < 0.04) and sustained(P < 0.05) virological response. There was a high frequency of vitamin D deficiency among the Egyptian HCV children, with significant decrease in bone density. The vitamin D level should be assessed before the start of antiviral treatment with the correction of any detected deficiency. CONCLUSION: Adding vitamin D to conventional Peg/RBV therapy significantly improved the virological response and helped to prevent the risk of emerging bone fragility. | Azza A Eltayeb Madleen Adel A Abdou Amal M Abdel-aal Mostafa H Othman | 2015 | World Journal of Gastroenterology2015，21，4： | 3 |
| 7 | Study of fully developed, liquid-metal, open-channel flow in a nearly coplanar magnetic field 显示文摘 | Morley N B Abdou M A | 1997 | Fusion Technology1997，31，： | 2 |
| 8 | EM用于污水灌溉对小白菜产量和土壤肥力的影响显示文摘合理的灌溉指标和方法,是污水灌溉安全高效进行的主要保证。在污水灌溉中引入EM技术,以小白菜为研究对象、盆栽试验为手段,研究了在奶牛场废水灌溉条件下,不同灌水下限条件对作物生长和土壤的影响。结果表明,奶牛场废水灌溉不会导致小白菜减产,而且能够增加土壤的速效氮和速效磷,在污水中添加EM进行灌溉,对土壤养分增加的效果更为明显。试验结果还显示70%和80%田间持水量的灌溉下限对污水灌溉较为适宜。但长期灌溉奶牛场废水是否会发生氮、磷的淋溶,污染地下水,还需进一步的研究。 | 廖林仙 邵孝侯 李洪良 Mouktari Abdou | 2007 | 农业环境科学学报2007，26，2： | 2 |
| 9 | On the numerical solutions of Fredholm-Volterra integral equation显示文摘 | Abdou M A Mohamed K I Ismail A S | 2003 | Applied Mathematics and Computation2003，146，： | 1 |
| 10 | Variational Iteration Method for Solving Burger's and Coupled Burger's Equations 显示文摘 | Abdou M A Soliman A A | 2005 | J Comput Appl Math2005，181，2： | 1 |
| 11 | Novel antibacterial lactoferrin peptides generated by rennet digestion and autofocusing technique 显示文摘 | Hend A Elbarbary Adham M Abdou EunYoung Park | 2010 | International Dairy Journal2010，，20： | 1 |
| 12 | Chapman-enskog-maximum entropy method on time-dependent neutron transport equation显示文摘 | ABDOU M A | 2006 | Journal of Quantitative Spectroscopy and Radiative Transfer2006，101，2： | 1 |
| 13 | Antimicrobial peptides derived from hen egg lyso- zyme with inhibitory effect against Bacillus species 显示文摘 | ABDOU AM HIGASHIGUCHI S ABOUELEININ AM | 2007 | Food Control2007，18，2： | 1 |
| 14 | Quantitative design and evaluation of enhancement/thresholding edge detectors显示文摘 | I E Abdou W K Pratt | 1979 | Proc IEEE1979，67，5： | 1 |
| 15 | The extended F-expansion method and its application for a class of nonlinear evolution equations显示文摘 | Abdou M A | 2007 | Chaos Solitons and Fractals2007，31，： | 1 |
| 16 | Antimi-crobial activities of Allium sativum,Allium cepaa,Raphanussativus,Capsicum frutescens,Eruca sativa,Allium kurrat onbacteria显示文摘 | Abdou I A Abou-Zeid A A El-Sherbeeny M R | 1972 | Qual Plant Mater Veg1972，22，： | 1 |
| 17 | Cationic and high affinity serum IgG anti-dsDNA antibodies in active lupus nephritis显示文摘 | Abdou NI | 1993 | J Clin Exp Immunol1993，94，： | 1 |
| 18 | Quantitative design and evaluation of enhancement thresholding edge detectors显示文摘 | Abdou I E Pratt W K | 1979 | Proc IEEE1979，67，5： | 1 |
| 19 | Assessment of monitored energy use and thermal comfort conditions in mosques in hot-humid climates 显示文摘 | MOHAMM ADS A + Homoud ADEL A Abdou I SM AIL M Bu- daiw i | 2009 | Energy and Buildings2009，41，6： | 1 |
| 20 | Evaluation of survivin and NF-kappaB in psoriasis, an immunohistochemical study显示文摘 | Abdou AG Hanout HM | 2008 | J Cutan Pathol2008，35，5： | 1 |
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