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8篇 您的检索式:作者名="Mirjam B. Zeisel"
    题名 作者 年代 出处 被引量
1Characterization of Hepatitis C Virus Particle Subpopulations Reveals Multiple Usage of the Scavenger Receptor BI for Entry Steps显示文摘Viet Loan Dao Thi Christelle Granier Mirjam B. Zeisel Maryse Guérin Jimmy Mancip Ophélia Granio Fran?ois Penin Dimitri Lavillette Ralf Bartenschlager Thomas F. Baumert Fran?ois-Lo?c Cosset Marlène Dreux 2012Journal of Biological Chemistry2012,,37:2
2Virus-host Interactions during Hepatitis C Virus Entry-Implications for Pathogenesis and Novel Treatment Approaches显示文摘Hepatitis C virus (HCV) is a member of the Flaviviridae family and causes acute and chronic hepatitis. Chronic HCV infection may result in severe liver damage including liver cirrhosis and hepatocellular carcinoma. The liver is the primary target organ of HCV, and the hepatocyte is its primary target cell. Attachment of the virus to the cell surface followed by viral entry is the first step in a cascade of interactions between the virus and the target cell that is required for successful entry into the cell and initiation of infection. This step is an important determinant of tissue tropism and pathogenesis; it thus represents a major target for antiviral host cell responses, such as antibody-mediated virus neutralization. Following the development of novel cell culture models for HCV infection our understanding of the HCV entry process and mechanisms of virus neutralization has been markedly advanced. In this review we summarize recent developments in the molecular biology of viral entry and its impact on pathogenesis of HCV infection, development of novel preventive and therapeutic antiviral strategies.Joachim Lupberger Mirjam B. Zeisel Anita Haberstroh Eva K. Schnober Sophie Krieger Eric Soulier Christine Thumann Cathy Royer Samira Fafi-Kremer Catherine Schuster Franoise Stoll-Keller Hubert E. Blum Thomas F. Baumert 2008Virologica Sinica2008,23,2:1
3miR-122 – a key factor and therapeutic target in liver disease显示文摘Simonetta Bandiera Sébastien Pfeffer Thomas F. Baumert Mirjam B. Zeisel 2014Journal of Hepatology2014,,:1
4Hepatitis C virus entry into hepatocytes: Molecular mechanisms and targets for antiviral therapies显示文摘Mirjam B. Zeisel Isabel Fofana Samira Fafi-Kremer Thomas F. Baumert 2010Journal of Hepatology2010,,3:1
5Virus–host interactions in hepatitis C virus infection: implications for molecular pathogenesis and antiviral strategies显示文摘Philippe Georgel Catherine Schuster Mirjam B. Zeisel Fran?oise Stoll-Keller Thomas Berg Seiamak Bahram Thomas F. Baumert 2010Trends in Molecular Medicine2010,,6:1
6Hepatitis C virus entry into hepatocytes: Molecular mechanisms and targets for antiviral therapies显示文摘Mirjam B. Zeisel Isabel Fofana Samira Fafi-Kremer Thomas F. Baumert 2010Journal of Hepatology2010,,3:1
7Getting closer to the patient: Upgrade of hepatitis C virus infection in primary human hepatocytes显示文摘Mirjam B. Zeisel Marine Turek Thomas F. Baumert 2010Journal of Hepatology2010,,2:1
8Host-targeting agents for prevention and treatment of chronic hepatitis C – Perspectives and challenges显示文摘Mirjam B. Zeisel Joachim Lupberger Isabel Fofana Thomas F. Baumert 2012Journal of Hepatology2012,,:1
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