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| 1 | Identification of Flowering Regulatory Genes in Allopolyploid Brassica juncea显示文摘Brassica juncea is an allopolyploid originating from the interspecific hybridization between Brassica rapa and Brassica nigra, which is of multiple usage as a vegetable, oilseed and condiment worldwide. Both vernalization and non-vernalization under long-day photoperiod can promote floral transition in B. juncea suggesting merged flowering pathways of its ancestors and better environmental adaptability. We identified genomewide flowering regulatory genes in B. juncea, which include 84 and 79 genes from A and B sub-genomes, respectively. Ka/Ks analysis revealed a purification effect on both photoperiod and vernalization flowering regulation pathways during evolution. Expression profile of those genes during long-day and vernalization treatments suggested Bju ACO4, Bju AFT1, Bju BFT4, Bju ASOC1 and Bju ASOC4 may be the major functional copies of B. juncea flowering regulation. Further functional studies about Bju COs showed three days delayed flowering time in Bju ACO4 or Bju BCO3 silenced plants. Increased transcription of all BjuFLCs in Bju ACO4 or Bju BCO3 silenced plants suggested interactions between photoperiod and vernalization pathways governing flowering time. Our findings provided flowering regulating networks in allopolyploid B. juncea. | Ning Zhao Chang Liu Yiqing Meng Zhongyuan Hu Mingfang Zhang Jinghua Yang | 2019 | Horticultural Plant Journal2019，5，3： | 6 |
| 2 | Effect of burden and origin sites of premature ventricular contractions on left ventricular function by 7-day Holter monitor显示文摘Recent studies have shown that premature ventricular contractions(PVCs) could enlarge the heart,but its risk factors are incompletely understood as a single 24-hour recording cannot reflect the true PVC burden due to day-to-day variability.Our purpose was to investigate the effect of burden and origin sites on left ventricular(LV) function in patients with PVCs by 7-day Holter electrocardiography(ECG).From May 2012 to August2013,112 consecutive patients with PVCs were recruited from the authors' affiliated hospital.All patients received2-dimensional transthoracic echocardiography,12-lead routing ECG and 7-days Holter ECG.Serum N-terminal probrain natriuretic peptide(NT-proBNP) levels were measured.A total of 102 participants with PVCs were included in the final analysis.Origin of PVCs from the tricuspid annulus had the highest burden and NT-proBNP level.LV papillary muscle had a higher LV ejection fraction(EF) level and a lower LV end-systolic dimension(ESD) than other PVC foci(P<0.05).The high burden group had a higher LV end-diastolic dimension(EDD) and LVESD but lower LVEF than the other two groups(P<0.05).Female,older age,physical work,and history of PVCs had a significantly positive correlation with symptoms.Male,older age,physical work,and high burden were positive predictors of enlarged LVEDD,LVESD and higher serum NT-proBNP level,but lower LVEF.Seven-day dynamic ECG Holter monitor showed the true PVC burden on patients with PVCs.PVCs with a lower burden or origin from the LV papillary muscle and the fascicle were relatively benign,while PVCs with a higher burden or origin from the tricuspid annulus may lead to cardiac dysfunction. | Wenhua Xu Mingfang Li Minglong Chen Bing Yang Daowu Wang Xiangqing Kong Hongwu Chen Weizhu Ju Kai Gu Kejiang Cao Hailei Liu Qi Jiang Jiaojiao Shi Yan Cui Hong Wang | 2015 | The Journal of Biomedical Research2015，29，6： | 4 |
| 3 | Mitochondrial retrograde regulation tuning fork in nuclear genes expressions of higher plants显示文摘In plant cells, there are three organelles: the nucleus, chloroplast, and mitochondria that store genetic information. The nucleus possesses the majority of genetic information and controls most aspects of organelles gene expression, growth, and development. In return, organelles also send signals back to regulate nuclear gene expression, a process defined as retrograde regulation. The best studies of organelles to nucleus retrograde regulation exist in plant chloroplast-to-nuclear regulation and yeast mitochondria-to-nuclear regulation. In this review, we summarize the recent understanding of mitochondrial retrograde regulation in higher plant, which involves multiple potential signaling pathway in relation to cytoplasmic male-sterility, biotic stress, and abiotic stress. With respect to mitochondrial retrograde regulation signal pathways involved in cytoplasmic male-sterility, we consider that nuclear transcriptional factor genes are the targeted genes regulated by mitochondria to determine the abnormal reproductive development, and the MAPK signaling pathway may be involved in this regulation in Brassica juncea. When plants suffer biotic and abiotic stress, plant cells will initiate cell death or other events directed toward recovering from stress. During this process, we propose that mitochondria may determine how plant cell responds to a given stress through retrograde regulation. Meanwhile, several transducer molecules have also been discussed here. In particular, the Paepe research group reported that leaf mitochondrial modulated whole cell redox homeostasis, set antioxidant capacity, and determined stress resistance through altered signaling and diurnal regulation, which is an indication of plant mitochondria with more active function than ever. | Jinghua Yang Mingfang Zhang Jingquan Yu | 2008 | Journal of Genetics and Genomics2008，35，2： | 2 |
| 4 | Eukaryotic Translation Initiation Factors Shape RNA Viruses Resistance in Plants显示文摘Viruses are representative of a global threat to agricultural production. Genetic resistance is the preferred strategy for the control of viral infection and against loss of crop yield. Viral protein synthesis requires host cellular factors for translating their viral RNAs, and for regulating their replication and cell to cell systemic movement. Therefore, the viruses are dependent on cellular translation factors. Mutations in the gene encoding eIF4E and eIF4G or their isoforms, eIFiso4 E, eIFiso4 G and eIF2Bβ have been mapped as a source of plant potyvirus while other genus of plant virus recessive resistance genes in many species are originated from these loci. Some of other plant translation factors, such as eIF3,eIF4 A-like helicases, eEF1A and eEF1B, which are required in interacting with viral RNAs and regulating various aspects of the infection cycle,have also been identified. Here, we summarized the mechanisms utilized by RNA viruses of eukaryotic plants and the essential roles of e IFs in virus infection. Moreover, we discussed the potential of e IFs as a target gene in the development of genetic resistance to viruses for crop improvement. This review highlighted newly revealed examples of abnormal translational strategies and provided insights into natural host resistance mechanisms that have been linked to 3 cap-independent translational enhancer activity. | Jannat Shopan Xiaolong Lv Zhongyuan Hu Mingfang Zhang Jinghua Yang | 2020 | Horticultural Plant Journal2020，6，2： | 2 |
| 5 | Synthesis, charac- terization, DNA binding properties, fluorescence studies and an- tioxidant activity of transition metal complexes with hesperetin-z-hydroxy benzoyl hydrazone 显示文摘 | Li Yong Yang Zhengyin Wang Mingfang | 2010 | J Fluoresc2010，20，4： | 1 |
| 6 | Thermally crosslinkable poly ( phenylene sulfide)/poly ( ether sulfone) polymerization of monomer reactant--polyimide blends 显示文摘 | LAI Mingfang YANG Yuming LIU Jingjiang | 2002 | Appl Polym Sci2002，83，： | 1 |
| 7 | Adaptation and mitigation for combating climate change - from singletojoint显示文摘Introduction:Adaptation and mitigation are two main approaches to combating climate change.Mitigation is considered as the most important tasks in dealing with climate change in scientific res earch,financial support and technical practices as global warming intensifes;while currently the warming trend still cannot be reversed,and adaptation task seemed to gain urgency although it is late-starting.The synergies and tradeoffs of these two strategies revealed increasingly importance on reduding adverse dimate effects.Research on synergistic relationships has developed from definition and feasible analysis,to the development of quantitative tools and exploration in practice and application,though the latter aspect is still in its initial stage.Outcomes/other.Our review shows that the traits of mitigation and adaptation,the difer-ences and similarities between them,then ilustrate the significance and mechanism of their synergies and tradeoffs.And it is explained that methods and applications of single and integrated models,and cost-effectiveness analysis.Discussion/Conclusion:We hold the opinion that the future research and applications should be enhanced in terms of four aspects:reinforcement of interrelations and common mecha nisms between mitigation and adaptation actions study;building and improving the monitoring and evaluating systems;promoting departmental and regional scale investiga-tions and applications;and establishing policy and security systems. | Chunli Zhao Yan Yan Chenxing Wang Mingfang Tang Gang Wu Ding Ding Yang Song | 2018 | Ecosystem Health and Sustainability2018，4，4： | 1 |
| 8 | Thermally crosslinkable poly (phenylene sulfide)/poly (ether sulfone)/polymerization of monomer reactant-polyimide blends显示文摘 | Mingfang Lai Yuming Yang Jingjiang Liu | 2002 | Journal of Applied Polymer Science2002，83，4： | 1 |
| 9 | Thermally crosslinkable poly(phenylene sulfide)/poly(ether sulfone)polymerization of monomer reactant polyamide blends显示文摘 | Lai Mingfang Yang Yuming | 2002 | Applied Polymer Science2002，83，： | 1 |
| 10 | The Morphology and Thermal Properties of Multi-walled Carbon Nanotube and Poly( hydroxybutyrate -co-hydroxyvalerate) Composite显示文摘 | Mingfang Lai Jing Li Jun Yang | 2004 | Polymer International2004，53，10： | 1 |
| 11 | Nedaplatin? versus cisplatin?based chemotherapy in the survival timeof patients with non?small cell lung cancer显示文摘 | Jinlu Shan Yanli Xiong Dong Wang Mingfang Xu Yi Yang Kan Gong Zhenzhou Yang Ge Wang Xueqin Yang | 2015 | Molecular and Clinical Oncology2015，，3： | 1 |
| 12 | Ti/Fe EUTECTIC REACTION PROCESS显示文摘获得在钛合金和不锈钢之间的令人满意的加入,学习 Ti-Fe 最容易溶解的反应的过程意义大。关于形成的液体的初步的研究,传播并且在纯 Ti 和纯 Fe 之间的接触反应的结构被执行在 1 120 “在在高周波的正式就职的不同成立时间的 C 加热了真空炉子。结果为 Fe 显示出那(像粒子)/Ti (像板) 接触反应夫妇,由于 Fe “ s 更高的密度比钛” s, Fe/Ti 最容易溶解的反应在像板的 Ti 的厚度方向发展,“命名免职效果”。没有,然后,最容易溶解的反应能被认识到在 Ti 和 Fe 原子之间内部散开,液相的形成率因此是很快的。为 Ti (像粒子)/ Fe (像板) 接触反应夫妇,最容易溶解的反应有一个强壮的方向,即最容易溶解的液体主要在 Ti 方面被形成,它导致 Ti 粒子的许多溶解和 Fe 碱金属的很小的溶解。在 Ti 的 Fe 的散开率决定最容易溶解的反应的整个过程,这能被看见,是表现了 Ti 的溶解率(像粒子)/ Fe (像板)比那 ofFe 低得多(像粒子) /Ti (像板),并且 Ti 的溶解率遵守方形的根法律。Whatevermeans Ti, Fe 被装配由,仅仅溶解过程能被成立,传播现象是模糊的,它涉及金属间化合的混合物的形成和“ Fe 的免职效果”。 | WU Mingfang MA Cheng YANG Min | 2006 | Chinese Journal of Mechanical Engineering2006，19，4： | 0 |
| 13 | A Secure Rotation Invariant LBP Feature Computation in Cloud Environment显示文摘In the era of big data,outsourcing massive data to a remote cloud server is a promising approach.Outsourcing storage and computation services can reduce storage costs and computational burdens.However,public cloud storage brings about new privacy and security concerns since the cloud servers can be shared by multiple users.Privacy-preserving feature extraction techniques are an effective solution to this issue.Because the Rotation Invariant Local Binary Pattern(RILBP)has been widely used in various image processing fields,we propose a new privacy-preserving outsourcing computation of RILBP over encrypted images in this paper(called PPRILBP).To protect image content,original images are encrypted using block scrambling,pixel circular shift,and pixel diffusion when uploaded to the cloud server.It is proved that RILBP features remain unchanged before and after encryption.Moreover,the server can directly extract RILBP features from encrypted images.Analyses and experiments confirm that the proposed scheme is secure and effective,and outperforms previous secure LBP feature computing methods. | Shiqi Wang Mingfang Jiang Jiaohua Qin Hengfu Yang Zhichen Gao | 2021 | Computers, Materials & Continua2021，，9： | 0 |
| 14 | Adaptive Reversible Visible Watermarking Based on Total Variation for BTC-Compressed Images显示文摘Few previous Reversible Visible Watermarking(RVW)schemes have both good transparency and watermark visibility.An adaptive RVW scheme that integrates Total Variation and visual perception in Block Truncation Coding(BTC)compressed domain,called TVB-RVW is proposed in this paper.A new mean image estimation method for BTC-compressed images is first developed with the help of Total Variation.Then,a visual perception factor computation model is devised by fusing texture and luminance characteristics.An adaptive watermark embedding strategy is used to embed the visible watermark with the effect of the visual perception factor in the BTC domain.Moreover,a lossless embedding method of the encrypted visible watermark is exploited to deter illegal watermark removal.The visible watermark can be removed since the visual perception factor and the estimated mean image remain unchanged before and after watermark embedding.Extensive experiments validate the superiority of the proposed algorithm over previous RVW schemes in BTC in terms of the visual quality of watermarked images and watermark visibility,and it can achieve a good balance between transparency and watermark visibility. | Hengfu Yang Mingfang Jiang Zhichen Gao | 2023 | Computers, Materials & Continua2023，，3： | 0 |
| 15 | Identification of MAM1s in Regulation of 3C Glucosinolates Accumulation in Allopolyploid Brassica juncea显示文摘Allopolyploid Brassica juncea is particularly enriched in sinigrin,a kind of 3C aliphatic glucosinolates(GSLs),giving rise to characteristic taste after picking.However,the molecular mechanism underlying 3C aliphatic GSLs biosynthesis in this species remains unknown.In this study,we genome-widely identified GSLs metabolic genes,indicating different evolutionary rate of GSLs metabolic genes between subgenomes of B.juncea.Eight methythioalkylmalate synthase(MAMs)homologs were identified from B.juncea,in which six MAM1s were located in chloroplast and the other two were not detected with any expression.Furthermore,BjMAM1-4,BjMAM1-5,and BjMAM1-6 displayed higher expression levels in leaves than other tissues.Silenced expression analysis revealed that BjMAM1-4 and BjMAM1-6 function in 3C and 4C aliphatic GSLs accumulation.The specificity of the substrate selection for the second cycle reaction is much lower than that of the first cycle,suggesting these genes may preferentially catalyze 3C aliphatic GSLs biosynthesis.Our study provides insights into the molecular mechanism underlying the accumulation of 3C aliphatic GSLs,thereby facilitating the manipulation of aliphatic GSLs content in B.juncea. | Zhangping Li Changtong Zhang Qingze Cai Yulan Zhou Zhongyuan Hu Mingfang Zhang Jinghua Yang | 2020 | Horticultural Plant Journal2020，6，6： | 0 |
| 16 | Optimal ordering policy for platelets:Data-driven method vs model-driven method显示文摘Platelets,one of the most significant materials in treating leukemia,have a limited shelf life of approximately five days.Because platelets cannot be manufactured and can only be centrifuged from whole or donated blood directly,an accurate ordering policy is necessary for the efficient use of this limited blood resource.Given this motivation,the present study examines an ordering policy for platelets to minimize the expected shortage and overage.Rather than using the two-step model-driven method that first fits a demand distribution and then optimizes the order quantity,we solve the issue using an integrated datadriven method.Specifically,the data-driven method works directly with demand data and does not rely on the assumption of demand distribution.Consequently,we derive theoretical insights into the optimal solutions.Through a comparative analysis,we find that the data-driven method has a mean anchoring effect,and the amounts of shortage and overage reduced by this method are greater than those reduced by the model-driven method.Finally,we present an extended model with the service level requirement and conclude that the order decided by the data-driven method can precisely satisfy the service level requirement;however,the order decided by the model-driven method may be either higher or lower than the service level requirement and can lead to a higher cost. | Mingfang Yang Xu Chen Zheng Luo | 2021 | Fundamental Research2021，1，5： | 0 |
| 17 | Light quality regulates plant biomass and fruit quality through a photoreceptor-dependent HY5-LHC/CYCB module in tomato显示文摘Increasing photosynthesis and light capture offers possibilities for improving crop yield and provides a sustainable way to meet the increasing global demand for food.However,the poor light transmittance of transparent plastic films and shade avoidance at high planting density seriously reduce photosynthesis and alter fruit quality in vegetable crops,and therefore it is important to investigate the mechanisms of light signaling regulation of photosynthesis and metabolism in tomato(Solanum lycopersicum).Here,a combination of red,blue,and white(R1W1B0.5)light promoted the accumulation of chlorophyll,carotenoid,and anthocyanin,and enhanced photosynthesis and electron transport rates by increasing the density of active reaction centers and the expression of the genes LIGHT-HARVESTING COMPLEX B(SlLHCB)and A(SlLHCA),resulting in increased plant biomass.In addition,R1W1B0.5 light induced carotenoid accumulation and fruit ripening by decreasing the expression of LYCOPENEβ-CYCLASE(SlCYCB).Disruption of SlCYCB largely induced fruit lycopene accumulation,and reduced chlorophyll content and photosynthesis in leaves under red,blue,and white light.Molecular studies showed that ELONGATED HYPOCOTYL 5(SlHY5)directly activated SlCYCB,SlLHCB,and SlLHCA expression to enhance chlorophyll accumulation and photosynthesis.Furthermore,R1W1B0.5 light-induced chlorophyll accumulation,photosynthesis,and SlHY5 expression were largely decreased in the slphyb1cry1 mutant.Collectively,R1W1B0.5 light noticeably promoted photosynthesis,biomass,and fruit quality through the photoreceptor(SlPHYB1 and SlCRY1)-SlHY5-SlLHCA/B/SlCYCB module in tomato.Thus,the manipulation of light environments in protected agriculture is a crucial tool to regulate the two vital agronomic traits related to crop production efficiency and fruit nutritional quality in tomato. | Jiarong Yan Juan Liu Shengdie Yang Chenghao Jiang Yanan Liu Nan Zhang Xin Sun Ying Zhang Kangyou Zhu Yinxia Peng Xin Bu Xiujie Wang Golam Jalal Ahammed Sida Meng Changhua Tan Yufeng Liu Zhouping Sun Mingfang Qi Feng Wang Tianlai Li | 2023 | Horticulture Research2023，10，12： | 0 |
| 18 | Tomato leaf curl New Delhi virus:an emerging plant begomovirus threatening cucurbit production显示文摘Tomato leaf curl New Delhi virus(ToLCNDV),a bipartite begomovirus,was first reported to infect tomato and has recently spread rapidly as an emerging disease to Cucurbitaceae crops.To date,the virus has been reported to infect more than 11 cucurbit crops,in 16 countries and regions,causing severe yield losses.In autumn 2022,ToLCNDV was first isolated from cucurbit plants in Southeastern coastal areas of China.Phylogenetic analysis established that these isolates belong to the Asian ToLCNDV clade,and shared high nucleotide identity and closest genetic relationship with the DNA-A sequence from the Chinese tomato-infecting ToLCNDV isolate(Accession no.OP356207)and the tomato New Delhi ToLCNDV-Severe isolate(Accession no.HM159454).In this review,we summarize the occurrence and distribution,host range,detection and diagnosis,control strategies,and genetic resistance of ToLCNDV in the Cucurbitaceae.We then summarize pathways that could be undertaken to improve our understanding of this emerging disease,with the objective to develop ToLCNDV-resistant cucurbit cultivars. | Lingmin Cai Yuzhen Mei Ruyi Ye Yun Deng Xuejun Zhang Zhongyuan Hu Xueping Zhou Mingfang Zhang Jinghua Yang | 2023 | aBIOTECH2023，4，3： | 0 |
| 19 | P-aminobenzoic acid promotes retinal regeneration through activation of Ascl1a in zebrafish显示文摘The retina of zebrafish can regenerate completely after injury.M ultiple studies have demonstrated that metabolic alte rations occur during retinal damage;however to date no study has identified a link between metabolites and retinal regeneration of zebrafish.Here,we performed an unbiased metabolome sequencing in the N-methyl-D-aspartic acid-damaged retinas of zebrafish to demonstrate the metabolomic mechanism of retinal regeneration.Among the differentially-ex pressed metabolites,we found a significant decrease in p-aminobenzoic acid in the N-methyl-D-aspartic acid-damaged retinas of zebrafish.Then,we investigated the role of p-aminobenzoic acid in retinal regeneration in adult zebrafish.Impo rtantly,p-aminobenzoic acid activated Achaetescute complex-like 1a expression,thereby promoting Müller glia reprogramming and division,as well as Müller glia-derived progenitor cell proliferation.Finally,we eliminated folic acid and inflammation as downstream effectors of PABA and demonstrated that PABA had little effect on Müller glia distribution.Taken together,these findings show that PABA contributes to retinal regeneration through activation of Achaetescute complex-like 1a expression in the N-methyl-Daspartic acid-damaged retinas of zebrafish. | Meihui He Mingfang Xia Qian Yang Xingyi Chen Haibo Li Xiaobo Xia | 2024 | Neural Regeneration Research2024，19，8： | 0 |
| 20 | Study on the Variation Characteristics of Haze Weather in Hubei Province during 1980-2012显示文摘This paper, using the method of 'the combination of 14 o'clock relative humidity, visibility and weather phenomena', selected haze days during 1980-2012 from 13 stations of Hubei Province, and studied years of variation characteristics of haze weather in Hubei Province. The results showed that the average annual haze days showed a fluctuant rising trend in whole from 1980 to 2012, but there were many peak value and valley value during the whole changing process; haze days of most stations showed an increasing trend, among which the stations with less than50 d haze days had a more obvious increasing trend, and the spatial distribution of annual mean haze days had distinct inhomogeneity. Haze days of Hubei Province presented the distribution characteristics of more in autumn and winter, and less in spring and summer, in which haze days during December-January were the most,and haze days during July-August were the least. Terrain had a big impact on local haze days, piedmont leeward zones were prone to haze days, mountainous regions were just the opposite. The research suggested that we should combine different situations with different stations instead of exclusively from the mean value of multiple stations when we analyze the mean change of haze days in a broader area, to investigate the overall changing trend and the reasons. | Tianxing SU Mingfang XU Xiang ZHOU Zaiqiang YANG Jijian YUAN Haiyan ZHANG | 2015 | Agricultural Science & Technology2015，16，1： | 0 |
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