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| 1 | 华东理工大学学报(社会科学版)投稿注意事项显示文摘影像发声(Photovoice)作为参与式行动研究的新方法,通过组织参与者拍摄照片并进行讨论的方式来激发个人和社区的改变。在社会工作介入和研究中,同样可以运用此方法来进行社区需求的评估和开展以增能为目标的介入实践。本文结合上海市T村外来务工家庭的母亲形象项目,介绍了影像发声法在实际操作过程中的基本程序,并探讨了运用影像发声法的优点与局限性。希望影像发声这一新的方法能为我国社会工作研究和实务工作者提供更多的有用工具。 | 朱眉华 吴世友 Mimi V.Chapman | 2012 | 华东理工大学学报(社会科学版)2012，27，4： | 9 |
| 2 | 流动家庭母亲的心声与社会工作的回应——基于T村母亲形象影像发声项目的分析显示文摘运用影像发声法研究流动家庭母亲的生存状况与面临的挑战发现,子女教育、医疗健康、生活环境和闲暇时光是她们的主要关注点。这些主题既反映了她们在家庭教育、健康保护、生存环境和流动历程中的艰辛与困惑,同时也表达了她们对未来生活、社会保障及改善社会政策与社区环境等方面的强烈呼声。影像发声作为一种社区需求的评估方法,有利于社会工作有效地回应流动家庭的需求,并在此基础上提供更适切的专业服务。 | 朱眉华 吴世友 Mimi V.Chapman | 2013 | 中国青年政治学院学报2013，32，5： | 9 |
| 3 | 食物与鼻咽癌——广州市居民鼻咽癌病例对照研究显示文摘1983年3月1日至1985年8月31日对经病理确诊,年龄在50岁以下的广州市居民鼻咽癌新发病例进行病例一对照研究。应用Logistic多因素回归分析方法来分析各项数据,结果如下: 1.在各个被调查时期,母亲和对象咸鱼摄入经常度与鼻咽癌发病有显著相关。 2.除咸鱼外,儿童期进食其他五种腌制食品或酱油表明与鼻咽癌发病呈显著相关。这五种腌制食品为鱼露、咸虾酱、腐乳、陈皮梅、嘉应子。而发病前三年进食这些食品显示与鼻咽癌发病无关。 3.在各个被调查时期,病例组较对照组更少进食新鲜蔬菜和水果,显示与鼻咽癌发病有相关。 4.检测咸鱼、鱼露、咸虾酱、腐乳、陈皮梅、嘉应子、西红柿对鼻咽癌发病的作用,有三种食物显示其在鼻咽癌发病上是作为独立的危险因素,它们是咸鱼、腐乳、陈皮梅,而西红柿则为保护因素。 综上述可见:从多个流行病学调查和实验室研究均表明:进食含有亚硝胺类致癌物的咸鱼与鼻咽癌发病密切相关,而且在儿童期越年幼进食,相对危险性越大。 | 黄腾波 Mimi C. Yu 朱锦柳 | 1993 | 癌症1993，12，1： | 8 |
| 4 | Substrate stiffness modulates bone marrow-derived macrophage polarization through NF-κB signaling pathway显示文摘The stiffness of the extracellular matrix(ECM)plays an important role in regulating the cellular programming.However,the mechanical characteristics of ECM affecting cell differentiation are still under investigated.Herein,we aimed to study the effect of ECM substrate stiffness on macrophage polarization.We prepared polyacrylamide hydrogels with different substrate stiffness,respectively.After the hydrogels were confirmed to have a good biocompatibility,the bone marrow-derived macrophages(BMMs)from mice were incubated on the hydrogels.With simulated by the low substrate stiffness,BMMs displayed an enhanced expression of CD86 on the cell surface and production of reactive oxygen species(ROS)in cells,and secreted more IL-1βand TNF-αin the supernatant.On the contrary,stressed by the medium stiffness,BMMs expressed more CD206,produced less ROS,and secreted more IL-4 and TGF-β.In vivo study by delivered the hydrogels subcutaneously in mice,more CD68+CD86+cells around the hydrogels with the low substrate stiffness were observed while more CD68+CD206+cells near by the middle stiffness hydrogels.In addition,the expressions of NIK,phosphorylated p65(pi-p65)and phosphorylated IκB(pi-IκB)were significantly increased after stimulation with low stiffness in BMMs.Taken together,these findings demonstrated that substrate stiffness could affect macrophages polarization.Low substrate stiffness promoted BMMs to shift to classically activated macrophages(M1)and the middle one to alternatively activated macrophages(M2),through modulating ROS-initiated NF-κB pathway.Therefore,we anticipated ECM-based substrate stiffness with immune modulation would be under consideration in the clinical applications if necessary. | Mimi Chen Yu Zhang Pinghui Zhou Xingzhi Liu Huan Zhao Xichao Zhou Qiaoli Gu Bin Li Xuesong Zhu Qin Shi | 2020 | Bioactive Materials2020，5，4： | 7 |
| 5 | 结肠镜检查病人疼痛程度和焦虑水平的调查研究显示文摘[目的]了解结肠镜检查病人的疼痛程度和焦虑水平。[方法]选择60例结肠镜检查病人,用视觉模拟评分法(VAS)和状态焦虑问卷(SAI)评估疼痛程度和焦虑水平。[结果]结肠镜检查病人检查中经历了中等程度的疼痛,检查前后焦虑水平比较有统计学意义(P<0.05)。[结论]医护人员应重视病人的主观感受,针对性地采取措施,控制结肠镜检查病人的疼痛及焦虑。 | 周会兰 蒋晓莲 Mimi My Tse | 2007 | 护理研究(中旬版)2007，21，2： | 7 |
| 6 | Archean-Paleoproterozoic Lithospheric Mantle at the Northern Margin of the North China Craton Represented by Tectonically Exhumed Peridotites显示文摘Tectonically emplaced peridotites from North Hebei Province, North China Craton, have retained an original harzburgite mineral assemblage of olivine(54%–58%) + orthopyroxene(40%–46%)+minor clinopyroxene(<1%)+spinel. Samples with boninite-like chemical compositions also coexist with these peridotites. The spinels within the peridotites have high-Al end-members with Al_2O_3 content of 30 wt % –50 wt %, typical of mantle spinels. When compared with experimentally determined melt extraction trajectories, the harzburgites display a high degree of melting and enrichment of SiO_2, which is typical of cratonic mantle peridotites. The peridotites display variably enriched light rare earth elements(REEs), relatively depleted middle REEs and weakly fractionated heavy REEs, which suggest a melt extraction of over 25% in the spinel stability field. The occurrence of arc-and SSZ-type chromian spinels in the peridotites suggests that melt extraction and metasomatism occurred mostly in a subduction-related setting. This is also supported by the geochemical data of the coexisting boninite-like samples. The peridotites have ^(187)Os/^(188)Os ratios ranging from 0.113–0.122, which is typical of cratonic lithospheric mantle. These ^(187)Os/^(188)Os ratios yield model melt extraction ages(TRD) ranging from 981 Ma to 2054 Ma, which may represent the minimum estimation of the melt extraction age. The Al_2O_3-^(187)Os/^(188)Os-proxy isochron ages of 2.4 Ga–2.7 Ga suggest a mantle melt depletion age between the Late Achaean and Early Paleoproterozoic. Both the peridotites and boninite-like rocks are therefore interpreted as tectonically exhumed continental lithospheric mantle of the North China Craton, which has experienced mantle melt depletion and subduction-related mantle metasomatism during the Neoarchean-Paleoproterozoic. | TIAN Wei WANG Shuangyue LIU Fenglin CHU Zhuyin WANG Bin CHEN Mimi Jennifer PRICHARD | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 5 |
| 7 | Lactobacillus reuteri-derived extracellular vesicles maintain intestinal immune homeostasis against lipopolysaccharideinduced inflammatory responses in broilers显示文摘Background:Lactobacillus reuteri strains are widely used as probiotics to prevent and treat inflammatory bowel disease by modulating the host’s immune system.However,the underlying mechanisms by which they communicate with the host have not been clearly understood.Bacterial extracellular vesicles(EVs)have been considered as important mediators of host-pathogen interactions,but their potential role in commensals-host crosstalk has not been widely studied.Here,we investigated the regulatory actions of EVs produced by L.reuteri BBC3,a gut-associated commensal bacterium of Black-Bone chicken,in the development of lipopolysaccharide(LPS)-induced intestinal inflammation in a chicken model using both in vivo and in vitro experiments.Results:L.reuteri BBC3 produced nano-scale membrane vesicles with the size range of 60-250 nm.Biochemical and proteomic analyses showed that L.reuteri BBC3-derived EVs(LrEVs)carried DNA,RNA and several bioactive proteins previously described as mediators of other probiotics’beneficial effects such as glucosyltransferase,serine protease and elongation factor Tu.In vivo broiler experiments showed that administration of LrEVs exerted similar effects as L.reuteri BBC3 in attenuating LPS-induced inflammation by improving growth performance,reducing mortality and decreasing intestinal injury.LrEVs suppressed the LPS-induced expression of pro-inflammatory genes(TNF-α,IL-1β,IL-6,IL-17 and IL-8),and improved the expression of anti-inflammatory genes(IL-10 and TGF-β)in the jejunum.LrEVs could be internalized by chicken macrophages.In vitro pretreatment with LrEVs reduced the gene expression of TNF-α,IL-1βand IL-6 by suppressing the NF-κB activity,and enhanced the gene expression of IL-10 and TGF-βin LPS-activated chicken macrophages.Additionally,LrEVs could inhibit Th1-and Th17-mediated inflammatory responses and enhance the immunoregulatory cells-mediated immunosuppression in splenic lymphocytes of LPS-challenged chickens through the activation of macrophages.Finally,we revealed that the reduced content of both vesicular proteins and nucleic acids attenuated the suppression of LrEVs on LPS-induced inflammatory responses in ex vivo experiments,suggesting that they are essential for the LrEVs-mediated immunoregulation.Conclusions:We revealed that LrEVs participated in maintaining intestinal immune homeostasis against LPSinduced inflammatory responses in a chicken model.Our findings provide mechanistic insight into how commensal and probiotic Lactobacillus species modulate the host’s immune system in pathogens-induced inflammation. | Rujiu Hu Hua Lin Mimi Wang Yuezhen Zhao Haojing Liu Yuna Min Xiaojun Yang Yupeng Gao Mingming Yang | 2021 | Journal of Animal Science and Biotechnology2021，12，3： | 5 |
| 8 | A randomized double-blind controlled trial: Impact of probiotics on diarrhea in patients treated with pelvic radiation显示文摘 | Mimi Demers Anne Dagnault Josée Desjardins | 2013 | Clinical Nutrition2013，，： | 3 |
| 9 | Activation of Piezo1 contributes to matrix stiffness-induced angiogenesis in hepatocellular carcinoma显示文摘Background:Despite integrin being highlighted as a stiffness-sensor molecule in matrix stiffness-driven angiogenesis,other stiffness-sensor molecules and their mechanosensory pathways related to angiogenesis in hepatocellular carcinoma(HCC)remain obscure.Here,we explored the interplay between Piezo1 and integrinβ1 in the mechanosensory pathway and their effects on HCC angiogenesis to better understand matrix stiffness-induced angiogenesis.Methods:The role of Piezo1 in matrix stiffness-induced angiogenesis was investigated using orthotopic liver cancer SD rat models with high liver stiffness background,and its clinical significance was evaluated in human HCC tissues.Matrix stiffness-mediated Piezo1 upregulation and activation were assayed using an in vitro fibronectin(FN)-coated cell culture system with different stiffness,Western blotting and Ca^(2+)probe.The effects of shPiezo1-conditioned medium(CM)on angiogenesis were examined by tube formation assay,wound healing assay and angiogenesis array.The underlying mechanism by which Piezo1 participated in matrix stiffness-induced angiogenesis was analyzed by microRNA quantitative real-time polymerase chain reaction(qRT-PCR),matrix stiffness measurement,dual-luciferase reporter assay,ubiquitination assay and co-immunoprecipitation.Results:Increased matrix stiffness significantly upregulated Piezo1 expression at both cellular and tissue levels,and high expression of Piezo1 indicated an unfavorable prognosis.High matrix stiffness also noticeably enhanced the activation level of Piezo1,similar to its expression level.Piezo1 knockdown significantly suppressed tumor growth,angiogenesis,and lung metastasis of HCC rat models with high liver stiffness background.shPiezo1-CM from HCC cells attenuated tube formation and migration abilities of vascular endothelial cells remarkably,and analysis of differentially expressed pro-angiogenic factors revealed that Piezo1 promoted the expression and secretion of vascular endothelial growth factor(VEGF),CXC chemokine ligand 16(CXCL16)and insulin-like growth factor binding protein 2(IGFBP2).Matrix stiffness-caused Piezo1 upregulation/activation restrained hypoxia inducible factor-1α(HIF-1α)ubiquitination,subsequently enhanced the expression of downstream pro-angiogenic factors to accelerate HCC angiogenesis.Besides,collagen 1(COL1)-reinforced tissue stiffening resulted in more expression of Piezo1 via miR-625-5p.Conclusions:This study unravels a new mechanism by which the inte-grinβ1/Piezo1 activation/Ca2+influx/HIF-1αubiquitination/VEGF,CXCL16 and IGFBP2 pathway participates in matrix stiffness-driven HCC angiogenesis.Simultaneously,a positive feedback regulation loop as stiff matrix/integrinβ1/miR-625-5p/Piezo1 and COL1/stiffer matrix mediates matrix stiffness-caused Piezo1 upregulation. | Miao Li Xi Zhang Mimi Wang Yaohui Wang Jiali Qian Xiaoxia Xing Zhiming Wang Yang You Kun Guo Jie Chen Dongmei Gao Yan Zhao Lan Zhang Rongxin Chen Jiefeng Cui Zhenggang Ren | 2022 | Cancer Communications2022，42，11： | 3 |
| 10 | 治疗 幽门螺杆菌根治后应用质子泵抑制剂可能增加胃癌发病风险显示文摘背景 幽门螺杆菌感染是胃癌发生最常见的诱因。幽门螺杆菌根治是否能降低或消除胃癌发病风险取决于根治时的风险。对于有黏膜损害和胃酸过少者,幽门螺杆菌根治可恢复泌酸。幽门螺杆菌根治后应用质子泵抑制剂(PPI)可极度减少胃酸分泌。然而,幽门螺杆菌根治后应用PPI对于胃癌发生风险的影响仍不清楚。 | Mimi Chang Tan David Y Graham 霍永丰(译) | 2018 | 英国医学杂志中文版2018，21，11： | 3 |
| 11 | Polyclonal and allergen-induced cytokine responses in adults with asthma: Resolution of asthma is associated with normalization of IFN-γ responses显示文摘 | Joanne M. Smart Elisabeth Horak Andrew S. Kemp Colin F. Robertson Mimi L.K. Tang | 2002 | The Journal of Allergy and Clinical Immunology2002，，3： | 2 |
| 12 | High performance electrocoagulation process in treating palm oil mill effluent using high current intensity application显示文摘Electrocoagulation process using high current intensity to treat palm oil mill effluent(POME) was investigated in this study.Various operating parameters such as electrolysis time, inter-electrode distance and initial pH were carried out to determine the efficient process condition on the removal of chemical oxygen demand(COD),biological oxygen demand(BOD) and suspended solids(SS).The highest treatment was achieved at 50 min with the removal efficiencies for COD, BOD and SS obtained as 85%, 83%, and 84%, respectively.More than 50 min treatment showed the fluctuated trends of removal efficiencies which can be considered insignificant.The application of higher current resulted in higher removals of organics while the gas bubbles also assisted in removing the pollutant particles by floatation.In an inter-electrode distance study, the removal efficiency decreased when inter-electrode distance was either higher or lower than 10 mm due to the increase of solution resistance and the decrease of anode active surface area.In initial pH study, it was found that high removal efficiencies were achieved in slightly acidic POME sample rather than in neutral or basic condition.An electrocoagulation process by using the optimum operating parameters was able to remove COD, BOD and SS up to 95%, 94% and 96% respectively.The experimental results confirm that application of high current intensity in electrocoagulation provided high treatment efficiency at a reduced reaction time. | Mohd Nasrullah A.W.Zularisam Santhana Krishnan Mimi Sakinah Lakhveer Singh Yap Wing Fen | 2019 | Chinese Journal of Chemical Engineering2019，27，1： | 2 |
| 13 | Abdominal incision tumor implantation following pneumoperitoneum laparoscopic procedurevs. Standard open incision in a syngeneic rat model显示文摘 | Peter S. Paik M.D. Takeyuki Misawa M.D. Mimi Chiang Ph.D. Jeffrey Towson B.A. Samuel Im B.A. Adrian Ortega M.D. Dr. Robert W. Beart M.D | 1998 | Diseases of the Colon & Rectum1998，，4： | 1 |
| 14 | Intrinsic vulnerability, hazard and risk mapping for karst aquifers: A case study 显示文摘 | Mimi Z A Assi A | 2009 | Journal of Hydrology2009，3114，34： | 1 |
| 15 | Development of NADPH-diaphorase expression in chemosensory systems of the opossum Monodelphis domestic显示文摘 | Lena SS Mimi H | 1998 | Developmental Brain Res1998，111，1： | 1 |
| 16 | Tourism development of world heritage sites in China: a geographic perspective 显示文摘 | Mimi Li Bihu Wu Liping Cai | 2008 | Tourism Management2008，，1： | 1 |
| 17 | Protein complexes and functional modules in molecular networks显示文摘 | Spirin V Mimy L A | 2003 | Proc Natl Acad Sci2003，100，12： | 1 |
| 18 | Causes of Death in U.S. Special Operations Forces in the Global War on Terrorism: 2001–2004显示文摘 | John B. Holcomb Neil R. McMullin Lisa Pearse Jim Caruso Charles E. Wade Lynne Oetjen-Gerdes Howard R. Champion Mimi Lawnick Warner Farr Sam Rodriguez Frank K. Butler | 2007 | Annals of Surgery2007，，6： | 1 |
| 19 | Performance Evaluation of Multicast ad Hoc On-Demand Distance Vector Protocol显示文摘 | Mobaideen W A Mimi J M Masoud F A | 2007 | Computer Communications2007，30，9： | 1 |
| 20 | The First Weeks of the First Year显示文摘 | Mimi Benjamin Kurt Earnest Doug Gruenewald Ginny Arthur | 2007 | New Directions for Student Servises2007，，117： | 1 |
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