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| 1 | 福林酚试剂法测定蛋白质显示文摘自1922年Wu(吴)提出用福林酚(Folin-酚)试剂测定蛋白质含量[1],已有许多采用这一试剂的改良分析操作进行血清陆”、抗原-抗体沉淀物[7-9]和胰岛素[10]中蛋白质含量测定的报道。虽然这一试剂以其灵敏度高和操作简便得到推荐,但并不适合普遍的生物化学应用。 | Lowry O H Rosebrough N J Farr A L Randall R J 陈祥娥 | 2011 | 食品与药品2011，13，3： | 34 |
| 2 | 晚期卵巢癌、输卵管癌及原发性腹膜癌腹腔镜肿瘤细胞减灭术的安全性及有效性研究显示文摘目的总结晚期卵巢癌、输卵管癌和腹膜癌患者行腹腔镜初次或间歇性肿瘤细胞减灭术的临床经验。方法回顾分析接受腹腔镜肿瘤细胞减灭术的晚期卵巢癌(FIGOⅡc期以上)、输卵管癌和原发性腹膜癌患者临床资料。结果 32名患者接受腹腔镜评估手术。17例接受全腹腔镜肿瘤细胞减灭术,其中88.2%为满意的肿瘤细胞减灭术;11例腹腔镜评估后转开腹肿瘤细胞减灭术,其中72.7%为满意的肿瘤细胞减灭术;4例仅进行活检和(或)姑息手术。腹腔镜组平均随访时间19.7月9,例无瘤生存6,例带瘤生存2,例因肿瘤死亡。开腹组平均随访时间25.8月,3例无瘤生存,5例带瘤生存,3例因肿瘤死亡。腹腔镜组术中失血量较少,术后住院时间较短(P=0.008和P=0.03),但手术时间及并发症发生率与开腹组相比无统计学差异。中位复发时间,腹腔镜组为31.7月,开腹组为21.5个月(P=0.3)。结论对于经过精心挑选的晚期卵巢癌、输卵管癌和原发性腹膜癌病例,采用腹腔镜进行诊断、分期和肿瘤细胞减灭术,在技术上是可行的。 | 李萌 熊光武 Farr R.Nezhat Shaghayegh M.DeNoble Connie S.Liu Jennifer E.Cho Douglas N.Brown Linus Chuang Herbert Gretz Prakash Saharia | 2012 | 中国微创外科杂志2012，12，2： | 11 |
| 3 | Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice显示文摘AIM: To study whether matrix metalloproteinase-9 (MMP-9) is a key factor in epithelial damage in the dextran sodium sulphate (DSS) model of colitis in mice.METHODS: MMP-9-deficient and wild-type (wt) mice were given 5% DSS in drinking water for 5 d followed by recovery up to 7 d. On d 5 and 12 after induction of colitis, gelatinases, MMP-2 and MMP-9, were measured in homogenates of colonic tissue by zymography and Western blot, whereas tissue inhibitor of metalloproteinases (TIMPs) were measured by reverse zymography. The gelatinolytic activity was also determined in supernatants of polymorphonuclear leukocytes (PMN) isolated from mice blood. Moreover, intestinal epithelial cells were stimulated with TNF-α to study whether these cells were able to produce MMPs. Finally, colonic mucosal lesions were measured by microscopic examination. RESULTS: On d 5 of colitis, the activity of MMP-9 was increased in homogenates of colonic tissues (0.24 ± 0.1 vs 21.3 ± 6.4, P < 0.05) and PMN from peripheral blood in wt (0.5 ± 0.1 vs 10.4 ± 0.7, P < 0.05), but not in MMP-9-deficient animals. The MMP-9 activity was also up-regulated by TNF-α in epithelial intestinal cells (2.5 ± 0.5 vs 14.7 ± 3.0, P < 0.05). Although colitis also led to increase of TIMP-1 activity, the MMP-9/TIMP-1 balance remained elevated. Finally, in the MMP-9-deficient colitic mice both the extent and severity of intestinal epithelialinjury were significantly attenuated when compared with wt mice. CONCLUSION: We conclude that DSS induced colitis is markedly attenuated in animals lacking MMP-9. This suggests that intestinal injury induced by DSS is modu-lated by MMP-9 and that inhibition of this gelatinase may reduce inflammation. | Alfredo Santana Carlos Medina Maria Cristina Paz-Cabrera Federico Díaz-Gonzalez Esther Farré Antonio Salas Marek W Radomski Enrique Quintero | 2006 | World Journal of Gastroenterology2006，12，40： | 9 |
| 4 | Economic growth and atmospheric pollution in Spain: discussing the environmental Kuznets curve hypothesis显示文摘 | Jordi Roca Emilio Padilla Mariona Farré Vittorio Galletto | 2001 | Ecological Economics2001，，1： | 3 |
| 5 | Efficacy of Buspirone, a Fundus-Relaxing Drug, in Patients With Functional Dyspepsia显示文摘 | Jan Tack Pieter Janssen Tatsuhiro Masaoka Ricard Farré Lukas Van Oudenhove | 2012 | Clinical Gastroenterology and Hepatology2012，，11： | 2 |
| 6 | Guidelines for the management of intravascular catheter-related infections显示文摘 | Mermel LA Farr BM Sherertz R J | | 0，，： | 2 |
| 7 | Comparative assessment of analytical and digital photogrammetric methods in the construction of dams of geomorphological forms 显示文摘 | Baily B Collier P Farres P | 2003 | Earth Surface Processes and Landforms2003，28，： | 1 |
| 8 | Protein measurement with the folin phenol reagent 显示文摘 | LOWRY O H ROSEBROUGH N J FARR A L | 1951 | Journal of Biological Chemistry1951，193，： | 1 |
| 9 | The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice 显示文摘 | Tang J Kozaki K Farr AG | 2005 | Am J Pathol2005，167，3： | 1 |
| 10 | Task characteristics, reward contingency, and intrinsic motivation显示文摘 | FARR J L | 1976 | Organizational Behavior and Human Performance1976，16，2： | 1 |
| 11 | Drug addiction显示文摘 | Cami J Farre M | 2003 | N Engl J Med2003，349，10： | 1 |
| 12 | CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro:lipopolysaccharide activation of epithelial cells revisited显示文摘 | Funda DP Tuckova L Farre MA | 2001 | Infect Immun2001，69，6： | 1 |
| 13 | Comparison of in vitro and in vivo efficieneies of a novel unit-dose liquid aerosol generator and a pressurized metered dose inhaler显示文摘 | Farr SJ Warren SJ Lloyd P | 2000 | Int J Pharm2000，198，： | 1 |
| 14 | Comparing Penman-Monteith and Priestley-Taylor approaches as reference-evapotranspiration inputs for modeling maize water-use under Mediterranean conditions a显示文摘 | Utset Angel Farre Imma Martinez-Cob Antonio | 2004 | Agricultural Water Management2004，66，3： | 1 |
| 15 | Vittorio galletto,economics growth and atmospheric pollution in spain:discussing the environmental kuznets curve hypothesis显示文摘 | JORDI ROCA EMILIO PADILLA MARIONA FARRE | 2001 | Ecological Economics2001，39，： | 1 |
| 16 | Degradation of Some Biorecalcitrant Pesticides by Homogeneous and Heterogeneous Photocatalytic Ozonation显示文摘 | FARRE M J FRANCH M I MALATO S | 2005 | Chemosphere2005，58，： | 1 |
| 17 | Prevention and control of antimicrobial resistant infections in intensive care patients显示文摘 | Salgado CD Ogragy N Farr BM | 2005 | Crit Care Med2005，33，10： | 1 |
| 18 | The global topography mission gains momentum 显示文摘 | Farr T Evans D zebker H | 1995 | Eos Trans American Geophys Union1995，76，21： | 1 |
| 19 | Retention rate and illicit opioid use during methadone maintenance interventions : a meta- analysis 显示文摘 | FARRE M MAS A TORRENS M | 2002 | Drug Alcohol Depend2002，65，3： | 1 |
| 20 | Ni- tric oxide synthase inhibition and food intake effects on motivation to eat and in female mice 显示文摘 | MORLEY J E FARR S A SUAREZ M D | 1995 | Pharma- cology Biochemistry and Behavior1995，50，3： | 1 |
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