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| 1 | STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo显示文摘 | Melanie Spitzner Birte Roesler Christian Bielfeld Georg Emons Jochen Gaedcke Hendrik A. Wolff Margret Rave‐Fr?nk Frank Kramer Tim Beissbarth Julia Kitz Jürgen Wienands B. Michael Ghadimi Reinhard Ebner Thomas Ried Marian Grade | 2014 | Int J Cancer2014，，4： | 2 |
| 2 | Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy显示文摘 | Carola H. Ries Michael A. Cannarile Sabine Hoves J?rg Benz Katharina Wartha Valeria Runza Flora Rey-Giraud Leon P. Pradel Friedrich Feuerhake Irina Klaman Tobin Jones Ute Jucknischke Stefan Scheiblich Klaus Kaluza Ingo H. Gorr Antje Walz Keelara Abiraj Ph | 2014 | Cancer Cell2014，，： | 2 |
| 3 | Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer显示文摘 | Geng Zhang Peijun He Hanson Tan Anuradha Budhu Jochen Gaedcke B. Michael Ghadimi Thomas Ried Harris G. Yfantis Dong H. Lee Anirban Maitra Nader Hanna H. Richard Alexander S. Perwez Hussain | 2013 | Clinical Cancer Research2013，，18： | 1 |
| 4 | Interpreting method comparison studies by use of the Bland-Altman plot:reflecting the importance of sample size by incorporating confidence limits and predefined error limits in the graphic显示文摘 | Najib Aziz Michael RI Sally SD | 2004 | Clinical Chemistry2004，50，11： | 1 |
| 5 | Does an interspinous device ( CoflexTM ) improve the outcome of decompressive surgery in lumbar spinal stenosis? One - year follow up of a prospective case control study of 60 patients 显示文摘 | Alexander RI Christian S Michael H | 2010 | Eur Spine2010，19，： | 1 |
| 6 | Convergence Results for Single-Step On-Policy Reinforcement-Learning Algorithms显示文摘 | Satinder Singh Tommi Jaakkola Michael L. Littman Csaba Szepesvári | 2000 | Machine Learning2000，，3： | 1 |
| 7 | Growth and reactivity of zinc and cadmium oxide nano-particles in zeolite显示文摘 | Michael Wark Henri ri Kessler Günter Schulz-Ekloff | 1997 | Microporous Materials1997，8，： | 1 |
| 8 | Convergence Results for Single-Step On-Policy Reinforcement-Learning Algorithms显示文摘 | Satinder Singh Tommi Jaakkola Michael L. Littman Csaba Szepesvári | 2000 | Machine Learning2000，，3： | 1 |
| 9 | Cemented Hip Arthroplasty With a Novel Cerclage Cable Technique for Unstable Intertrochanteric Hip Fractures显示文摘 | Chris Grimsrud Raul J. Monzon Jonathan Richman Michael D. Ries | 2005 | The Journal of Arthroplasty2005，，3： | 1 |
| 10 | Interleukin-6 and tumor necrosis factor - a production after acute psychological stress, exercise, and infused isoprotereno:differential effects and pathways显示文摘 | Marion UG Paul M Michael RI | 2004 | Psychosomat Med2004，130，： | 1 |
| 11 | Convergence Results for Single-Step On-Policy Reinforcement-Learning Algorithms显示文摘 | Satinder Singh Tommi Jaakkola Michael L. Littman Csaba Szepesvári | 2000 | Machine Learning2000，，3： | 1 |
| 12 | Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression显示文摘 | Wartman Lukas D Larson David E Xiang Zhifu Ding Li Chen Ken Lin Ling Cahan Patrick Klco Jeffery M Welch John S Li Cheng Payton Jacqueline E Uy Geoffrey L Varghese Nobish Ries Rhonda E Hoock Mieke Koboldt Daniel C McLellan Michael D Schmid | 2011 | Journal of Clinical Investigation2011，，： | 1 |
| 13 | Studies on pharma- cological effects of Russell' s viper and Saw -scaled viper cenom and its neutrakization by chicken egg yolk antibodies显示文摘 | MEENATCHISUNDARAM S PARAMESWA RI G MICHAEL A | 2008 | Int J Im- munopharmaco12008，8，8： | 1 |
| 14 | Interpret ing Method Com- parisonStudiesby U seof the Bland-Altman Plot: Reflecting the Import ance ofSample Sizeby Incorporat ing Con fidence Limit sand Predefined ErrorLimit sinthe Graphic显示文摘 | Najib Aziz Michael RI Sally SD | 2004 | Clinical Chemistry2004，50，11： | 1 |
| 15 | Cost-analysis of inpatient and outpatient parenteral antimicrobial therapy in orthopaedics: A systematic literature review显示文摘BACKGROUND Increasing numbers of total joint arthroplasties and consecutive revision surgery are associated with the risk of periprosthetic joint infections (PPJI). Treatment of PPJI is complex and associated with immense socio-economic burden. One treatment aspect is parenteral antiinfective therapy, which usually requires an inpatient setting [Inpatient parenteral antibiotic therapy (IPAT)]. An alternative is outpatient parenteral treatment [Outpatient parenteral antibiotic therapy (OPAT)]. To conduct a health economic cost-benefit analysis of OPAT, a detailed cost analysis of IPAT and OPAT is required. So far, there is a lack of knowledge on the health economic effects of IPAT and OPAT for PPJI. AIM To review an economic comparison of IPAT and OPAT. METHODS A systematic literature review was performed through Medline following the PRISMA guidelines. RESULTS Of 619 identified studies, 174 included information of interest and 21 studies were included for quantitative analysis of OPAT and IPAT costs. Except for one study, all showed relevant cost savings for OPAT compared to IPAT. Costs for IPAT were between 1.10 to 17.34 times higher than those for OPAT. CONCLUSION There are only few reports on OPAT for PPJI. Detailed analyses to support economic or clinical guidelines are therefore limited. There is good clinical evidence supporting economic benefits of OPAT, but more high quality studies are needed for PPJI. | Christoph Kolja Boese Philipp Lechler Michael Frink Michael Hackl Peer Eysel Christian Ries | 2019 | World Journal of Clinical Cases2019，7，14： | 0 |
| 16 | Targeting growth hormone function: strategies and therapeutic applications显示文摘Human growth hormone(GH)is a classical pituitary endocrine hormone that is essential for normal postnatal growth and has pleiotropic effects across multiple physiological systems.GH is also expressed in extrapituitary tissues and has localized autocrine/paracrine effects at these sites.In adults,hypersecretion of GH causes acromegaly,and strategies that block the release of GH or that inhibit GH receptor(GHR)activation are the primary forms of medical therapy for this disease.Overproduction of GH has also been linked to cancer and the microvascular complications that are associated with diabetes.However,studies to investigate the therapeutic potential of GHR antagonism in these diseases have been limited,most likely due to difficulty in accessing therapeutic tools to study the pharmacology of the receptor in vivo.This review will discuss current and emerging strategies for antagonizing GH function and the potential disease indications. | Man Lu Jack U.Flanagan Ries J.Langley Michael P.Hay Jo K.Perry | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 0 |
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