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	题名	作者	年代	出处	被引量
1	Theoretical and experimental study on lipophilicity and wound healing activity of ginger compounds显示文摘Objective:To correlate the chromatographic and computational method to calculate lipophilicity of selected ginger compounds and to observe the effects of log P on wound healing.Methods:Mixtures of acetonitrile and water with acetonitrile content between 95%and 50%v/v in 5%increments were kept separately in 10 different chromatographic chambers,saturated with solvent for 2 h.Spots were observed under UV light atλ=254 nm p-anisaldehyde used as a spraying reagent Theoretical calculation was done using the Alogps 2.1 online program at www.vcclab.org/lab/alogps.For percentage wound contraction,five groups of animal(mice)(25-30 g)of either sex were selected.Wound were created on dorsal surface of animals using toothed forceps,scalpel and pointed scissors.The wound areas were calculated using vernier caliper.After making wound mice were orally administered 35 mg/kg 6-shogoal,6-gingerol,8-gingerol and 10-gingerol respectively.Croup E as the control group received tap water.Results:The Iipophilicity values determined in thin layer chromatography were correlated with the theoretically calculated various log P by linear regression analysis.Significant correlations were found between log P values calculated by software program and the experimental reversedphase thin-layer chromatography data.Order of wound healing property of ginger compounds is directly dependent on lipophilieity i.e.more lipophilic compound has highest activity.Conclusions:Experimentally determined lipophilieity(R_(MO))values were correlated with log P determined by software's and found satisfactory.Lipophilieity(R_(MO)is a useful parameter for the determination and prediction of biological activity of ginger compounds.	Mohammed Afroz Bakht Mohammed F.Alajmi Perwez Alam Aftab Alam Prawez Alam Tariq Mohammed Aljarba	2014	Asian Pacific Journal of Tropical Biomedicine2014，4，4：	2
2	An approach to predictive detection for service management显示文摘	Zhang Fan Hellerstein J L Perwez Shahabuddin	1999	Symposium on Integrated Network Management1999，，：	1
3	Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer显示文摘	Geng Zhang Peijun He Hanson Tan Anuradha Budhu Jochen Gaedcke B. Michael Ghadimi Thomas Ried Harris G. Yfantis Dong H. Lee Anirban Maitra Nader Hanna H. Richard Alexander S. Perwez Hussain	2013	Clinical Cancer Research2013，，18：	1
4	Importance Sampling for the Simulation of Highly Reliable Markovian Systems 显示文摘	Perwez Shahabuddin	1994	Management Science1994，40，3：	1
5	Large Deviations In Multifactor Portfolio Credit Risk显示文摘	Paul Glasserman Wanmo Kang & Perwez Shahabud- din	2007	Mathematical Finance2007，17，3：	1
6	Cystic replacement of kidney mimicking ascites显示文摘	PERWEZ Y SINGH H GONDAL PK	2003	Indian J Surgery2003，65，3：	1
7	p53:25 years after its discovery 显示文摘	LOME J HOFSETH S PERWEZ H	2004	Trends Pharmacol Sci2004，25，4：	1
8	p53 biological network: at the crossroads of the cellular - stress response pathway and molecular carcinogenesis显示文摘	PERWEZ H HARRIS C	2006	Nippon Med Sch2006，73，2：	1
9	p53: 25 years after its discovery显示文摘	Lorne JH Perwez H Curtis CH	2004	Trends Pharmacol Sci2004，25，4：	1
10	p53: 25 years after its discovery显示文摘	Lome JH Perwez H Curtis CH	2004	Trends Pharmacol Sci2004，25，4：	1
11	p53:25 years after its discovery显示文摘	Lorne JH Perwez H Curtis CH	2004	Trends in Pharmacol Sci2004，25，4：	1
12	p53:25 years after its discovery 显示文摘	Lome JH Perwez H Curtis CH	2004	Trends in Pharmacological Sciences2004，25，4：	1
13	p53: 25 yearsafter its discovery 显示文摘	LORNE J H PERWEZ H CURTIS C H	2004	Trends Pharmacol Sci2004，25，4：	1
14	p53 : 25 years after its discovey 显示文摘	Loome JH Perwez H Curtis CH	2004	Trends in Pharmacol Sci2004，25，4：	1
15	Dynamic Batching Policies for an On-Demand Video Server显示文摘	Asit Danl Dinkar Sitaraml Perwez Shahabuddin	1996	Multimedia Systems1996，，：	1
16	Scheduling Poli- cries for an On-Demand Video Server with Batching 显示文摘	Asit Danl Dinkar Sitaraml Perwez Shahahuddin	1994	Proceedings of the Second ACM International Cont:rence on Multi- media1994，，：	1
17	Radical cause of cancer 显示文摘	Perwez H S Hofseth L J Harris C C	2003	Nat Rev Cancer2003，3，：	1
18	p53:25 years after its discovery显示文摘	Lorne JH Perwez H Curtis CH	2004	Trends Pharmacol Sci2004，25，4：	1
19	Radical cause of cancer 显示文摘	Perwez H S Hofseth L J Harris C C	2003	Nat Rev Cancer2003，3，：	1
20	Portfolio value-at-Risk with heavy-tailed risk factors显示文摘	Paul G Philip H Perwez S	2002	Mathematica Finance2002，12，3：	1

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