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| 1 | Our experience in sperm morphology assessment显示文摘 | Julia Irene Ariagno Susana Mercedes Curi Patricia Chenlo Herberto Ernesto Hector Repetto Mercedes Norma Pugliese Luis Alberto Palaoro Melba Sardi Gabriela Ruth Mendeluk | 2011 | Asian Journal of Andrology2011，13，2： | 4 |
| 2 | Analysis of the in vitro degradation and the in vivo tissue response to bi-layered 3D-printed scaffolds combining PLA and biphasic PLA/bioglass components--Guidance of the inflammatory response as basis for osteochondral regeneration显示文摘The aim of the present study was the in vitro and in vivo analysis of a bi-layered 3D-printed scaffold combining a PLA layer and a biphasic PLA/bioglass G5 layer for regeneration of osteochondral defects in vivo Focus of the in vitro analysis was on the(molecular)weight loss and the morphological and mechanical variations after immersion in SBF.The in vivo study focused on analysis of the tissue reactions and differences in the implant bed vascularization using an established subcutaneous implantation model in CD-1 mice and established histological and histomorphometrical methods.Both scaffold parts kept their structural integrity,while changes in morphology were observed,especially for the PLA/G5 scaffold.Mechanical properties decreased with progressive degradation,while the PLA/G5 scaffolds presented higher compressive modulus than PLA scaffolds.The tissue reaction to PLA included low numbers of BMGCs and minimal vascularization of its implant beds,while the addition of G5 lead to higher numbers of BMGCs and a higher implant bed vascularization.Analysis revealed that the use of a bi-layered scaffold shows the ability to observe distinct in vivo response despite the physical proximity of PLA and PLA/G5 layers.Altogether,the results showed that the addition of G5 enables to reduce scaffold weight loss and to increase mechanical strength.Furthermore,the addition of G5 lead to a higher vascularization of the implant bed required as basis for bone tissue regeneration mediated by higher numbers of BMGCs,while within the PLA parts a significantly lower vascularization was found optimally for chondral regeneration.Thus,this data show that the analyzed bi-layered scaffold may serve as an ideal basis for the regeneration of osteochondral tissue defects.Additionally,the results show that it might be able to reduce the number of experimental animals required as it may be possible to analyze the tissue response to more than one implant in one experimental animal. | Mike Barbeck Tiziano Serra Patrick Booms Sanja Stojanovic Stevo Najman Elisabeth Engel Robert Sader Charles James Kirkpatrick Melba Navarro Shahram Ghanaati | 2017 | Bioactive Materials2017，2，4： | 3 |
| 3 | Hierarchical Fusion of Multiple Classifiers for Hyper-spectral Data Analysis显示文摘 | Shailesh K Joydeep G Melba M C | 2002 | Pattern Analysis & Application2002，5，2： | 1 |
| 4 | New macroporous calcium phosphate glass ceramic for guided bone regeneration 显示文摘 | Melba N Sergio DV Salvador M | 2004 | Biomaterials2004，25，14： | 1 |
| 5 | Hierarch- ical Fusion of Multiple Classifiers for Hyperspectral Data Analy- sis显示文摘 | Kumar Shailesh Ghosh Joydeep Crawford Melba M | 2002 | Pattern Analysis&Applications2002，5，2： | 1 |
| 6 | Point-to-plane registration of terrestrial laser scans显示文摘 | Darion Grant James Bethel Melba Crawford | 2012 | ISPRS Journal of Photogrammetry and Remote Sensing2012，，： | 1 |
| 7 | Business Models of Scholarly Publish-ers :Implications for Open Access显示文摘 | Villarroya Anna Claudio -Gonzalez Melba AbadalErnest Melero Remedios | 2012 | Profesional de la Informa-cion2012，21，2： | 1 |
| 8 | Regulation of the angiopoietin-like protein 3 gene by LXR显示文摘 | Kaplan R Zhang T Melba Hernandez | 2003 | J Lipid Res2003，44，1： | 1 |
| 9 | Recommendations for animal DNA forensic and identity testing显示文摘 | Bruce Budowle Paolo Garofano Andreas Hellman Melba Ketchum Sree Kanthaswamy Walther Parson Wim Haeringen Steve Fain Tom Broad | 2005 | International Journal of Legal Medicine2005，，5： | 1 |
| 10 | Hierarchical Fusion of Multiple Classifiers for Hyperspectral Data Analysis显示文摘 | Shailesh Kumar Joydeep Ghosh Melba M. Crawford | 2002 | Pattern Analysis & Applications2002，，2： | 1 |
| 11 | Academic libraries and outreach services through preeol- lege programs: a proactive collaboration 显示文摘 | Melba J | 1993 | Reference Services Review1993，21，4： | 1 |
| 12 | Relevance of PEG in PLA-based blends for tissue engineering 3D-printed scaffolds显示文摘 | Tiziano Serra Monica Ortiz-Hernandez Elisabeth Engel Josep A. Planell Melba Navarro | 2014 | Materials Science & Engineering C2014，，： | 1 |
| 13 | Disease and health management in Asian aquaculture显示文摘 | MELBA G B ROHANA P S RICHARD A S | 2005 | Veterinary Parasitology2005，132，： | 1 |
| 14 | Arsenic -mediated activation of the NrO-Keapl antioxidant pathway显示文摘 | Alexandria L Samantha AW Melba CJ | 2013 | J Biochem Mol Toxicol2013，2，： | 1 |
| 15 | Prevalence and Correlates of Poor Self-Rated Health in the United States: The National Elder Mistreatment Study显示文摘 | Ananda B. Amstadter Angela Moreland Begle Josh M. Cisler Melba A. Hernandez Wendy Muzzy Ron Acierno | 2010 | American Journal of Geriatric Psychiatry2010，，7： | 1 |
| 16 | Disease and health management in Asian aquaculture显示文摘 | Melba G. Bondad-Reantaso Rohana P. Subasinghe J. Richard Arthur Kazuo Ogawa Supranee Chinabut Robert Adlard Zilong Tan Mohamed Shariff | 2005 | Veterinary Parasitology2005，，3： | 1 |
| 17 | The emerging role of the Nrf2–Keap1 signaling pathway in cancer显示文摘 | Melba C. Jaramillo Donna D. Zhang | 2013 | Genes & Development2013，，20： | 1 |
| 18 | New Macroporous Calcium Phosphate Glass Ceramic for Guided Bone Regeneration显示文摘 | Melba N Sergio D V Salvador M | 2004 | Biomaterials2004，25，18： | 1 |
| 19 | 光学相干断层成像评估高血压性视网膜病变神经元损伤应用价值的研究显示文摘背景当前高血压的患病率呈逐年增长趋势,其眼部并发症高血压视网膜病也日益受到关注。然而目前对于高血压性视网膜病变中神经元损伤的研究尚少。目的本研究以光学相干断层成像检查为检查手段,探究其在高血压性视网膜病变中神经元损伤评估中的应用和重要价值。方法纳入2019年3月—2020年7月于Hospital Clínico Quirúrgico“Hermanos Ameijeiras”(HHA医院)就诊的102例高血压患者为研究对象,同时纳入45名健康受试者,监测24 h动态血压,取24 h舒张压和收缩压的平均动脉血压值,测量眼压,计算眼灌注压。检测视盘区视网膜神经纤维(RNFL)厚度和黄斑区神经节细胞复合层(GCC)厚度。依据血压控制情况将患者分为血压控制组(n=51)和血压未控制组(n=51),45名健康受试者为对照组。采用Pearson相关性分析或Spearman秩相关分析探究血压、眼灌注压、视网膜病变与GCC厚度和血压、眼灌注压与视网膜病变的相关性,采用R 3.5.3软件进行中介作用分析。结果3组研究对象人种、收缩压、舒张压、平均动脉压、眼压、眼灌注压、视网膜病变比较,差异有统计学意义(P<0.05)。血压未控制组平均RNFL厚度低于对照组(P<0.05),血压控制组、血压未控制组GCC平均厚度低于对照组,血压未控制组GCC最小值低于对照组(P<0.05)。相关性分析结果显示,GCC平均厚度、上方GCC厚度、颞下方CCG厚度与收缩压、舒张压、眼灌注压、视网膜病变呈负相关(P<0.05),颞上方GCC厚度与收缩压、舒张压、眼灌注压呈负相关(P<0.05),下方GCC厚度与舒张压呈负相关(P<0.05),视网膜病变与收缩压、舒张压、眼灌注压呈正相关(P<0.05)。中介效应结果显示,“收缩压→GCC平均厚度→高血压性视网膜病变”效应显著,收缩压与GCC平均厚度呈正相关,GCC平均厚度与高血压性视网膜病变呈正相关(P<0.05)。收缩压对高血压性视网膜病变发生风险具有直接影响(β=0.013,95%CI=0.007~0.020,P<0.001),GCC平均厚度部分介导了收缩压对高血压性视网膜病变发生风险的影响(β=0.117,95%CI=0.014~0.360,P=0.04),中介效应占总效应的11.7%。结论光学相干断层成像检查是一种无创的眼科检查方法,可优于普通眼底检查提前发现高血压性视网膜神经元受损情况,对高血压导致视神经受损的不可逆盲和高血压靶器官受损进行早期预防和预警。 | 赵润泽 孙小佳 Melba Marquez Hernandez 窦国睿 | 2024 | 中国全科医学2024，27，9： | 0 |
| 20 | Alternative Dispute Settlement Mechanisms: Towards Restorative Justice in Yucatan, Mexico显示文摘 | Carlos Alberto Macedonio Hernandez Lucely Martina Carballo Solis Melba Angelina Mendez Fernaindez Edith Cisneros-Cohernour | 2016 | US-China Education Review(B)2016，6，2： | 0 |
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