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| 1 | Surveillance and diagnosis of hepatocellular carcinoma: A systematic review显示文摘BACKGROUND Hepatocellular carcinoma (HCC) appears in most of cases in patients with advanced liver disease and is currently the primary cause of death in this population.Surveillance of HCC has been proposed and recommended in clinical guidelines to obtain earlier diagnosis,but it is still controversial and is not accepted worldwide.AIM To review the actual evidence to support the surveillance programs in patients with cirrhosis as well as the diagnosis procedure.METHODS Systematic review of recent literature of surveillance (tools,interval,cost-benefit,target population) and the role of imaging diagnosis (radiological non-invasive diagnosis,optimal modality and agents) of HCC.RESULTS The benefits of surveillance of HCC,mainly with ultrasonography,have been assessed in several prospective and retrospective analysis,although the percentage of patients diagnosed in surveillance programs is still low.Surveillance of HCC permits diagnosis in early stages allows better access to curative treatment and increases life expectancy in patients with cirrhosis.HCC is a tumor with special radiological characteristics in computed tomography and magnetic resonance imaging,which allows highly accurate diagnosis without routine biopsy confirmation.The actual recommendation is to perform biopsy only in indeterminate nodules.CONCLUSION The evidence supports the recommendation of performing surveillance of HCC in patients with cirrhosis susceptible of treatment,using ultrasonography every 6 mo.The diagnosis evaluation of HCC can be established based on noninvasive imaging criteria in patients with cirrhosis. | Sonia Pascual Cayetano Miralles Juan M Bernabé Javier Irurzun Mariana Planells | 2019 | World Journal of Clinical Cases2019，7，16： | 5 |
| 2 | Prospective Evaluation of Emergency Versus Delayed Laparoscopic Cholecystectomy for Early Cholecystitis显示文摘 | Alfonso S. Serralta Jose L. Bueno Manuel R. Planells David R. Rodero | 2003 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2003，，2： | 3 |
| 3 | From quantum dots to quantum wires:electronic structyre of semiconductor nanorods显示文摘 | Planelles J Royo R Ballester | 2009 | Phys Rev B2009，80，： | 1 |
| 4 | Osteoblast-like cellular response to dynamic changes in the ionic extracellular environ- ment produced by calcium-deficient hydroxyapatite显示文摘 | Gustavsson J Ginebra MP Planell J | 2012 | J Mater Sci Mater Med2012，23，10： | 1 |
| 5 | Development and cell response of a new biodegradable composite scefold for guided bone regeneration 显示文摘 | Ginebra M P Driessens F C M Planell J A | 2004 | Journal of Materials Sci-ence: Materials in Medicine2004，，15： | 1 |
| 6 | HCV screening in blood donations using RT-PCR in mini-pool:the experience in Spain after routine use for 2 years显示文摘 | Eiras A Sauleda S Planelles D | 2003 | Transfusion2003，43，6： | 1 |
| 7 | Prospective evaluation of emergency versus delayed laparoscopic cholecystectomy for early cholecystitis显示文摘 | Serralta AS Bueno JL Planells MR | 2003 | Surg Laparosc Endosc Percutan Tech2003，13，2： | 1 |
| 8 | Behaviour of normal grain growth kinetics in single phase titanium and titanium alloys显示文摘 | Gil F J Planell J A | 2000 | Materials Science and Engineering A2000，283，12： | 1 |
| 9 | The role of different types of acid site in the cracking of alkanes on zeolite catalysts显示文摘 | Corma A Planelles J Sanchez J | 1985 | J Catal1985，93，1： | 1 |
| 10 | A finite element study of mechanical stimuli in scaffolds for bone tissue engineering 显示文摘 | Sandino C Planell J A Lacroix D | 2008 | J Biomech2008，41，5： | 1 |
| 11 | Treatment of a non -vitaimmature incisor with mineral trioxide aggregate(MTA)显示文摘 | Maroto M Barberia E Planells P et ai | 2003 | Dentaltraumatology2003，19，： | 1 |
| 12 | Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines显示文摘 | Lee CM Fuhrman CB Planelles V | 2006 | Clin Cancer Res2006，12，1： | 1 |
| 13 | Field performance of Pi- nus halepenis planted in Medierranean arid conditions: relative influence of seedling morphology and mineral nutriton 显示文摘 | Oliet J A Planelles R Artero F | 2009 | New Forests2009，37，3： | 1 |
| 14 | Calcium phosphate cements as bone drug delivery systems:A review显示文摘 | Ginebra M P Traykova T Planell J A | 2006 | Journal of Controlled Release2006，113，2： | 1 |
| 15 | The role of different types of acid site in the cracking of alkanes on zeolite catalysts显示文摘 | CORMA A PLANELLES J SáNCHEZ-MARíN J TOMáS F | 1985 | J Catal1985，93，1： | 1 |
| 16 | Prospectiveevaluation of emergency versus delayed laparoscopiccholecystectomy for early cholecystitis显示文摘 | Serralta AS Bueno JL Planells MR | 2009 | Surg Lapa-rosc Endosc Percutan Tech2009，13，： | 1 |
| 17 | Phosphatidylinositol 3- kinase inhibition by LY294002 radiosensitizes human cervical cane- er cell lines显示文摘 | Lee CM Fuhrman CB Planelles V | 2006 | Clin Cancer Res2006，12，1： | 1 |
| 18 | Inhibition of glyco- gen synthase kinase-3 by lithium correlates with re- duced tauopathy and degeneration in vivo显示文摘 | Noble W Planel E Zehr C | 2005 | Proc Natl Acad Sci2005，102，14： | 1 |
| 19 | Calcium phosphate cements as bone drug delivery systems:a review 显示文摘 | MP Ginebra T Traykova JA Planell | 2006 | J Controlled Release2006，113，2： | 1 |
| 20 | HCV screening in blood donations using RT-PCR in mini-pool: the experience in Spain after routine use for 2 years显示文摘 | Eiras A Sauleda S Planelles D | 2003 | Transfusion2003，43，6： | 1 |
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