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11篇 您的检索式:作者名="Mcpherson PS"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Binding of Vac14 to neuronal nitric oxide synthase: Characterisation of a new internal PDZ-recognition motif 显示文摘Lemaire JF McPherson PS 2006FEBS Lett2006,50,:1
3Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals显示文摘 McPherson PS Schmid SL 1995Nature1995,374,:1
4Variants of DENND1B associated with asthma in children显示文摘Marat AL Mcpherson PS 2010N Engl J Med2010,363,10:1
5The connecdenn fanlily, Rab35 gua- nine nueleotide exchange factors interfacing with the elathrin machinery 显示文摘Marat AL McPherson PS 2010J Biol Chem2010,285,10:1
6The V0 sector of the V ATPase, synaptobrevin, and synaptophysin are associated on synat ic vesicles in a Triton X -100 -resistant,freeze- thrawing sensitive, complex显示文摘Galli T McPherson PS De Camilli P 1996J Biol Chem1996,271,4:1
7Differential immunohistochemical localization of inositol 1,4,5-trisphosphate- and ryanodine-sensitive Ca^2+ release channels in rat brain 显示文摘Sharp AH McPherson PS Dawson TM 1993J Neurosci1993,13,:1
8The ryanodine receptor/Ca^2+ release channel显示文摘McPherson PS Campbell KP 1993J Biol Chem1993,268,13:1
9The ryanodine receptor/Ca2+ release channel显示文摘 Campbell DP 1993J Biochem1993,268,13:1
10Differential immunohistochemical localization of inositol 1,4,5-trisphosphate-and ryanodine-sensitive Ca2+release channels in rat brain显示文摘Sharp AH Mcpherson PS Dawson TM Aoki C Campbell KP Snyder SH 1993J Neurosci1993,13,7:1
11Variants of DENND1B associated with asthma in children显示文摘Marat AL McPherson PS 0,,10:1
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