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| 1 | Transversus abdominis plane infiltration for laparoscopic gastric banding: A pilot study显示文摘AIM: To estimate an effect size for the transversus abdominis plane(TAP) infiltration on quality of recovery in patients undergoing laparoscopic gastric band surgery. METHODS: The pilot study was a randomized, double blinded, placebo controlled trial. Patients undergoing laparoscopic gastric band surgery were randomized to receive a bilateral TAP infiltration with 20 mL of 0.5% ropivacaine or saline. The evaluated outcomes included quality of recovery-40(QoR-40) at 24 h, postoperative opioid consumption and pain. Data was examined using the Mann-Whitney U test. RESULTS: Nineteen subjects were recruited. There was a positive trend favoring the TAP infiltration group in global QoR-40 scores at 24 h after surgery, median [interquartile range(IQR)] of 175.5(170-189) com-pared to 170(160-175) in the control group(P = 0.06). There also a positive trend toward a lower cumulative opioid consumption in the TAP infiltration group, median(IQR) of 7.5(2.5-11.5) mg iv morphine equivalents compared to 13(7-21.5) in the control group(P = 0.07). Correlation analysis(Spearman's Rho) demonstrated an inverse relationship between 24 h cumulative opioid consumption and global QoR-40 scores,-0.49(P = 0.03). CONCLUSION: The use of multimodal analgesic techniques to reduce opioid related side effects is particularly desirable in morbidly obese patients undergoing gastric reduction surgery. The TAP infiltration seems to have a clinically important effect in reducing postoperative opioid consumption and improve quality of recovery after laparoscopic gastric band surgery in morbid obese patients. Future studies to confirm the beneficial effects of the TAP infiltration in these patients are warranted. | Gildasio S De Oliveira Jr Paul Fitzgerald Shireen Ahmad John Kim Rohit Rahangdale Robert McCarthy | 2014 | World Journal of Gastrointestinal Surgery2014，6，2： | 4 |
| 2 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 3 | Enzymatic Degradability of Poly(lactide) :Effects of chain stereochemistry and material crystallinity 显示文摘 | REEVE M MCCARTHY S P GROSS R A | 1996 | Macromolecules1996，29，23： | 1 |
| 4 | Perceived occupational stress in nurses working in Ireland 显示文摘 | McCarthy VJ Power S Greiner BA | 2010 | Occup Med (Lond)2010，60，8： | 1 |
| 5 | A cost, profit, and efficiency analysis of performing carpal tunnel surgery in the operating room versus the clinic setting in the United States显示文摘 | Chatterjee A McCarthy J E Montagne S A | 2011 | Ann Plast Surg2011，66，3： | 1 |
| 6 | Review of konjac glucomannan显示文摘 | Dav 6 V McCarthy S P | 1997 | Journal of Environmental Polymer Degradation1997，5，4： | 1 |
| 7 | Perceptions of Contractual Risk Alloca- tion in Construction Supply Chains 显示文摘 | Loosemore M McCarthy C S | 2008 | Journal of Professional Issues in Engineering Education and Practice2008，134，1： | 1 |
| 8 | Acid mine drainage arising from gold mining activity in Johannesburg,South Africa and environs显示文摘 | Naicker K Cukrowska E McCarthy T S | 2003 | Environmental Pollution2003，22，1： | 1 |
| 9 | Diagnosis of acute flank pain:value of unenhanced helical CT显示文摘 | Smith RC Verga M McCarthy S | 1996 | Am J Radiol1996，166，： | 1 |
| 10 | Colloidal transport: the facilitated movement of contaminants into groundwater 显示文摘 | Richards B K McCarthy J F Steenhuis T S | 2007 | Journal of Soil & Water Conservation2007，62，3： | 1 |
| 11 | Perception of contractu- al risk allocation in construction supply chains 显示文摘 | Loosemore M C S McCarthy | 2008 | Journal of Professional Issues in Education and Prac- tice2008，，1： | 1 |
| 12 | 显示文摘 | MARSHALL D J RUDNICK K A MCCARTHY S G | 2006 | Vaccine2006，24，3： | 1 |
| 13 | Inter-leukin-18 enhances Th1 immunity and tumor protec-tion of a DNA vaccine显示文摘 | Rudnick K A McCarthy S G | 2006 | Vaccine2006，24，： | 1 |
| 14 | Cysteamine-induced enhancement of growth hormone-releasing factor (GRF) immuno-reactivity in arcuate neurons:morphological evidence for putactive somatostatin/GRF interactions within hypothalamus 显示文摘 | Tannenbaum G S McCarthy G F | 1990 | Endocrinology1990，127，5： | 1 |
| 15 | The effect of nanoclays on the properties of PLLA-modified polymers part 1 : Mechanical and thermal properties 显示文摘 | LEWITUS D MCCARTHY S OPHIR A | 2006 | J Polym Envi- ron2006，14，2： | 1 |
| 16 | Electrospun silk material systems for wound healing显示文摘 | S E Wharram X Zhang D L Kaplan S P McCarthy | | 0，，： | 1 |
| 17 | Self-efficacy and writing 显示文摘 | McCarthy P Meier S & Rinderer R | 1985 | College Composition and Communication1985，，36： | 1 |
| 18 | Association of the metabolic syndrome with both vigorous and moderate physical activity显示文摘 | RENNIE K L MCCARTHY N YAZDGERDI S etal | 2003 | Int J Epidemiol2003，32，4： | 1 |
| 19 | Functionalized silk-based biomaterials for bone formation显示文摘 | Sofia S McCarthy M B Gronowicz G | 2001 | J Biomed Mater Res2001，54，1： | 1 |
| 20 | Liquid crystalline, rheological and thermal properties of konjac glucomannan 显示文摘 | Dave V Sheth M McCarthy S P | 1998 | Polymer1998，39，5： | 1 |
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