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    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2The role of cholecystokinin in interlcukin-1-induced anorexia显示文摘DAUN J M MCCARTHY D O 1993Physiol Behav1993,54,:1
3Broadband ultrasound attenuation of the calcaneus predicts lumbar and femoral neck density in Caucasian women:a prelininary study显示文摘Baran DT McCarthy CK Leahey D 1991Osteoporos Int1991,1,2:1
4Intra-event variability of Escherichia coli and total suspended solids in ur- ban stormwater runoff显示文摘McCarthy D T Hathaway J M Hunt W F 2012Water Research2012,46,20:1
5Functionalized carbon nanotubes for plasmid DNA gene delivery显示文摘Pantarotto D Singh R McCarthy D 2004Angew Chem Int Ed2004,43,:1
6Biomass and nitrogen uptake by heterotrophic bacteria during the spring phytoplankton bloom in the NorthAtlantic Ocean显示文摘Kirchman D L Ducklow H W McCarthy J J 1994Deep-Sea Research Ⅰ1994,41,:1
7Redefining the stormwater first flush phenomenon 显示文摘BACH P M MCCARTHY D T DELETIC A 2010Water Research2010,44,8:1
8Bone density ligand, sclerostin, directly inleracts with LRP5 but not LRPSG171V to modulate Wnt activity显示文摘Ellies D L Viviano B McCarthy J el al 2006J Bone Miner Res2006,21,11:1
9显示文摘MARSHALL D J RUDNICK K A MCCARTHY S G 2006Vaccine2006,24,3:1
10Inter-leukin-18 enhances Th1 immunity and tumor protec-tion of a DNA vaccine显示文摘 Rudnick K A McCarthy S G 2006Vaccine2006,24,:1
11The uptake of dissolved nitrogenous nutrients by Lake Kinnert (Israel)microplankton 显示文摘MCCARTHY J J WYNNE D BERMAN T 1982Limnology Oceanography1982,27,:1
12Lens opacities classification system Ⅱ(LOCS Ⅱ)显示文摘Chylack LT Jr Leske MC McCarthy D 1989Arch Ophthalmol1989,107,7:1
13Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cy- tokine profiles 显示文摘D'Mahony L McCarthy J Kelly P 2005Gastroenterology2005,128,3:1
14The effect of nanoclays on the properties of PLLA-modified polymers part 1 : Mechanical and thermal properties 显示文摘LEWITUS D MCCARTHY S OPHIR A 2006J Polym Envi- ron2006,14,2:1
15The develop- ment of a novel approach for assessment of the first flush in urban stormwater discharges显示文摘BACH P M MCCARTHY D T DELETIC A 2010Water Science and Technol- ogy2010,61,10:1
16Electrospun silk material systems for wound healing显示文摘S E Wharram X Zhang D L Kaplan S P McCarthy 0,,:1
17Extracellular electron transfer via microbial nanowires 显示文摘Reguera G Mccarthy K D Mehta T 2005Nature2005,435,:1
18Epstein-Barr virus induced virus-associated hemophagocytic syndrome and monoclonal TCR-beta rearrangement:a case report显示文摘Bird G Peel D McCarthy K 1997Hematol Oncol1997,15,1:1
19Estimating ecesis for tree-ring dating of moraines:A comparative study from the Canadian Cordillera显示文摘McCarthy D P Luckman B H 1993Arctic and Alpine Research1993,25,1:1
20Colloid transport in the subsurface:past,present,and future challengesv显示文摘McCarthy J F Mckay L D 2004Vadose zone journal2004,3,:1
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