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7篇 您的检索式:作者名="Mayank Patel"
    题名 作者 年代 出处 被引量
1Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug显示文摘The purpose of the present study was to investigate the interaction of Cinnarizine(CIN)with Hydroxypropyl-β-Cyclodextrin(HPβCD)in the presence of Hydroxy Acids(HA).Various binary and ternary systems of CIN with HPβCD and HA were prepared by kneading and coevaporation methods.For the ternary systems,HA were tried in three different concentrations.The interaction in solution phase was studied in detail by the phase solubility method,and the solid phase interactions were characterized by Fourier Transform Infrared(FTIR)spectroscopy,Differential Scanning Calorimetry(DSC),X-Ray Diffractometry(XRD),Scanning Electron Microscopy(SEM)and Proton Nuclear Magnetic Resonance(^1H-NMR).Phase solubility revealed the positive effect of HA on the complexation of CIN with HPβCD.Solid phase characterization confirmed the formation of inclusion complex in the ternary systems.Solubility and dissolution studies illustrated that out of three different concentrations tried,HA were most effective at the 1 M concentration level.Ternary systems were very effective in improving the solubility as well as dissolution profile of CIN than the CIN–HPβCD binary systems.FTIR,^1H-NMR and Molecular docking studies gave some insight at molecular level that actually which part of CIN was interacting with the HPβCD.Molecular docking and free energy calculation even enlighten the role of tartaric acid in increasing solubility of CIN in the ternary system.Mayank Patel Rajashree Hirlekar 2019Asian Journal of Pharmaceutical Sciences2019,14,1:2
2Robotic retroperitoneal partial nephrectomy显示文摘Mayank Patel James Porter 2013World Journal of Urology2013,,:2
3Critical care of the obese and bariatric surgical patient显示文摘Daniela Levi Elliot R Goodman Mayank Patel Yevgeny Savransky 2003Critical Care Clinics2003,,1:1
4What Causes Disability After Transient Ischemic Attack and Minor Stroke?: Results From the CT And MRI in the Triage of TIA and minor Cerebrovascular Events to Identify High Risk Patients (CATCH) Study显示文摘Shelagh B. Coutts Jayesh Modi Shiel K. Patel Heidi Aram Andrew M. Demchuk Mayank Goyal Michael D. Hill 2012Stroke2012,,11:1
5Cavitation After Acute Symptomatic Lacunar Stroke Depends on Time, Location, and MRI Sequence显示文摘Francois Moreau Shiel Patel M. Louis Lauzon Cheryl R. McCreary Mayank Goyal Richard Frayne Andrew M. Demchuk Shelagh B. Coutts Eric E. Smith 2012Stroke2012,,7:1
6Pet Waste Management by Chemical Recycling: A Review显示文摘Vijaykumar Sinha Mayank R. Patel Jigar V. Patel 2010Journal of Polymers and the Environment2010,,1:1
7Robotic retroperitoneal surgery: a contemporary review显示文摘Mayank Patel James Porter 2013Current Opinion in Urology2013,,:1
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