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| 1 | Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘 | Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick | 2010 | The Lancet2010，，9726： | 4 |
| 2 | RANK-ligand and osteoprotegerin as biomarkers in the differentiation between periprosthetic joint infection and aseptic prosthesis loosening显示文摘AIM To assess serum levels of RANK-ligand(RANKL) and osteoprotegerin(OPG) as biomarkers for periprosthetic joint infection(PJI) and compare their accuracy with standard tests.METHODS One hundred and twenty patients presenting with a painful total knee or hip arthroplasty with indication for surgical revision were included in this prospective clinical trial. Based on standard diagnostics(joint aspirate, microbiological, and histological samples) and Musculoskeletal Infection Society consensus classification,patients were categorized into PJI, aseptic loosening,and control groups. Implant loosening was assessed radiographically and intraoperatively. Preoperative serum samples were collected and analyzed for RANKL, OPG, calcium, phosphate, alkaline phosphatase(AP), and the bone-specific subform of AP(b AP). Statistical analysis was carried out, testing for significant differences between the three groups and between stable and loose implants. RESULTS All three groups were identical in regards to age, gender, and joint distribution. No statistically significant differences in the serum concentration of RANKL(P = 0.16) and OPG(P = 0.45) were found between aseptic loosening and PJI, with a trend towards lower RANKL concentrations and higher OPG concentrations in the PJI group. The RANKL/OPG ratio was significant for the comparison between PJI and non-PJI(P = 0.005). A ratio > 60 ruled out PJI in all cases(specificity: 100%, 95%CI: 89, 11% to 100.0%) but only 30% of non-PJI patients crossed this threshold. The positive predictive value remained poor at any cut-off. In the differentiation between stable and loose implants, none of the parameters measured(calcium, phosphate, AP, and b AP) showed a significant difference, and only AP and b AP measurements showed a tendency towards higher values in the loosened group(with P = 0.09 for AP and P = 0.19 for b AP). CONCLUSION Lower RANKL and higher OPG concentrations could be detected in PJI, without statistical significance. | Max J Friedrich Matthias D Wimmer Jan Schmolders Andreas C Strauss Milena M Ploeger Hendrik Kohlhof Dieter C Wirtz Sascha Gravius Thomas M Randau | 2017 | World Journal of Orthopedics2017，8，4： | 4 |
| 3 | Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘 | Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick | 2010 | 2010 (9726)2010，，9726： | 3 |
| 4 | Neoadjuvant and adjuvant therapy for resectable hepatocellular carcinoma: review of the randomised clinical trials显示文摘 | Jonathan D Schwartz Myron Schwartz John Mandeli Max Sung | 2002 | Lancet Oncology2002，，10： | 3 |
| 5 | Plant Phenomics:Emerging Transdisciplinary Science显示文摘Humankind is facing an unprecedented challenge to produce enough food for the coming decades because of population growth and increase in the average demand per capita,changes in climate conditions,and limitations in arable land area,as well as pressure on the water and resources.Two main avenues should be concurrently taken to increase crop productivity:improving genetics to get more efficient and resilient crops and developing optimal crop management practices.The description and understanding of crop functioning will therefore be instrumental both for genetic improvement and crop management.It will help to associate functional traits with the genome which will accelerate genetic progress by having more efficient techniques to design ideotypes adapted to particular pedoclimatic and crop management conditions and create them from the available genetic diversity. | Seishi Ninomiya Frédéric Baret Zong-Ming(Max)Cheng | 2019 | Plant Phenomics2019，1，1： | 2 |
| 6 | LAVES PHASE ALLOYS FOR HIGH TEMPERATURE APPLICATIONS显示文摘Ternary Laves phases with transition metals and aluminium were overviewed with respect to their use for structural high temperature applications. The relation between constitution, phase stability, crystal structure and basic mechanical properties was discussed. The crystal structure-hexagonal C14 structure or cubic C15 structure-is a function of atomic radii and valence electron concentration. A strong positive correlation of basic mechanical properties-hardness, yield stress-with the sublimation energy of the phases was found. The brittle to ductile transition temperature was observed at about 60% of the melting temperature. The regarded ternary Laves phases allow alloying to form stable equilibria with the less hard and brittle B2 aluminides. Advantageous examples are alloys of type NbNiAl NiAl, TaNiAl NiAl, and TaFeAl FeAl. Multiphase NiAl Ta Cr alloys are regarded as promising for structural high temperature applications and have been selected for a materials development which aims at applications in gas turbines at temperatures above those of Ni base superalloys, such alloy can be prepared by ingot metallurgy and powder metallurgy and hot forming is possible. Characteristic data were presented with respect to mechanical behaviour. The alloys showed a high thermoshock resistance in spite of the comparatively high brittle to ductile transition temperature. The prospects of alloy development were discussed. | G.Sauthoff Max Planck Institut für Eisenforschung Gmbh., D 40074 Düsseldorf, Germany | 1999 | 中国有色金属学会会刊:英文版1999，9，S1： | 2 |
| 7 | Depression and psychiatric disease associated with outcomes after anterior cruciate ligament reconstruction显示文摘While most patients with an anterior cruciate ligament(ACL) injury indicate satisfaction with surgical intervention, a significant proportion still do not return to pre-injury level of function or sport. Psychiatric comorbidities, such as depression, have recently been associated with poor clinical outcomes after ACL reconstruction(ACLR). To date, no article has yet examined how depression affects ACLR outcomes and how potential screening and intervention for psychological distress may affect postoperative activity level. The purpose of this review is to delineate potential relationships between depression and ACLR outcome, discuss clinical implications and identify future directions for research. | Hao-Hua Wu Max Liu Joshua S Dines John D Kelly Grant H Garcia | 2016 | World Journal of Orthopedics2016，7，11： | 2 |
| 8 | Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial显示文摘 | Wendy S Atkin Rob Edwards Ines Kralj-Hans Kate Wooldrage Andrew R Hart John MA Northover D Max Parkin Jane Wardle Stephen W Duffy Jack Cuzick | 2010 | The Lancet . 2010 (9726)2010，，： | 2 |
| 9 | A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease显示文摘 | Siobhan B O’Neill Patrick D Mc Laughlin Lee Crush Owen J O’Connor Sebastian R Mc Williams Orla Craig Anne Marie Mc Garrigle Fiona O’Neill Jackie Bye Max F. Ryan Fergus Shanahan Michael M Maher | 2013 | European Radiology2013，，： | 2 |
| 10 | Solid propulsion for space applications: An updated roadmap显示文摘 | Jean-Francois Guery I-Shih Chang Toru Shimada Marilyn Glick Didier Boury Eric Robert John Napior Robert Wardle Christian Pérut Max Calabro Robert Glick Hiroto Habu Nobuhiro Sekino Gilles Vigier Bruno d’Andrea | 2009 | Acta Astronautica2009，，1： | 2 |
| 11 | Softwood cuttings for propagation of red alder planting stock显示文摘 | Radwan M A T A Max D W Johnson | 1989 | New For1989，3，： | 1 |
| 12 | Methane hydrate:a frontier for exploration of new gas resources 显示文摘 | Max M D Lowrie A | 1996 | Journal of Petroleum Geology1996，19，2： | 1 |
| 13 | Computer aided design fluid power systems显示文摘 | MAX D DON R | 1982 | Proceeding of the National Conference on Power Transnission Volume 1x 9th Annual Meeting1982，9，1： | 1 |
| 14 | Schedule generation and reeonfiguration for parallel machines显示文摘 | LUH P B HOITOMT D J MAX E | 1990 | IEEE Transactions on Robotics and Automation1990，6，6： | 1 |
| 15 | Comparative Evaluation of Multiresolution Optimization Strategies for Muhimodality Image Registration by Maximization of Mutual Information 显示文摘 | F Maxes D Vandermeulen P Suetens | 1999 | Medical Image Anal1999，3，1： | 1 |
| 16 | Understanding innovation in small and medium-sized enterprises: A process manifest 显示文摘 | Tim E Rick D Max M | 2005 | Technovation2005，25，10： | 1 |
| 17 | Expression of CD4 on Epstein-Barr virus-immortalized B cells显示文摘 | Hoennscheidt C Max D Richter N | 2009 | Scand J lmmunol2009，70，3： | 1 |
| 18 | Outcome after duodenum-preserving pancreatic head resection is improved compared with classic Whipple procedure in the treatment of chronic pancreatitis显示文摘 | Witzigmann H Max D Uhlmann Vf | 2003 | Surger-y2003，134，： | 1 |
| 19 | Tectono-sedimentary controls on the likelihood of gas hydrate occurrence near Taiwan显示文摘 | McDonnell S L Max M D Cherkis N Z | 2000 | Marine and Petroleum Geology2000，17，： | 1 |
| 20 | Effects of nitrogen on grown-in oxygen precipitates in large diameter Czochralski silicon 显示文摘 | YU X G YANG D R YANG J S MAX Y LI L B QUE D L | 2003 | Chin J Semicond2003，24，1： | 1 |
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