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| 1 | Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair显示文摘AIM To determine endothelin-1(ET-1)concentration before and after surgical coarctectomy and evaluate its association with left ventricular geometric change.METHODSA prospective,cohort study of 24 patients aged 2 d to 10years with coarctation of the aorta undergoing surgical repair.A sub-cohort of patients with age<1 mo was classified as'neonates'.Echocardiograms were performed just prior to surgery and in the immediate post-op period to assess left ventricle mass index and relative wall thickness(RWT).Plasma ET-1 levels were assessed at both time points.Association between ET-1 levels and ventricular remodeling was assessed.RESULTSPatients<1 year demonstrated higher pre-op ET-1 than post-op(2.8 pg/m L vs 1.9 pg/m L,P=0.02).Conversely,patients>1 year had no change in ET-1 concentration before and after surgery(1.1 vs 1.4,NS).Pre-op,patients<1 year demonstrated significantly higher ET-1 than older children(2.8 vs 1.1,P=0.001).Post-op there was no difference between the age groups(1.9 vs 1.4,NS).Neither RWT nor left ventricle mass index(LVMI)varied from pre-op to post-op.The subset of neonates showed a strong positive correlation between pre-op ET-1 and RWT(r=0.92,P=0.001).Patients with ET-1>2 pg/m L preop demonstrated higher LVMI(65.7 g/m^(2.7) vs 38.5 g/m^(2.7),P=0.004)and a trend towards higher RWT(45%vs39%,P=0.07)prior to repair than those with lower ET-1concentration.CONCLUSIONET-1 concentration is significantly variable in the perioperative period surrounding coarctectomy.Older children and infants have different responses to surgical repair suggesting different mechanisms of activation. | Benjamin Steven Frank Tracy T Urban Suhong Tong Courtney Cassidy Max B Mitchell Christopher S Nichols Jesse A Davidson | 2017 | World Journal of Cardiology2017，9，12： | 2 |
| 2 | Softwood cuttings for propagation of red alder planting stock显示文摘 | Radwan M A T A Max D W Johnson | 1989 | New For1989，3，： | 1 |
| 3 | Stand structure in east side old-growth ponderosa pine forests of oregon and northern Califomia显示文摘 | YOUNG BLOOD A MAX T COE K | 2004 | Forest Ecology and Management2004，199，： | 1 |
| 4 | Influence of culti-var,maturity storage,and storage conditions on phe-nolic composition and enzymatic browning of pear fruits显示文摘 | Marie J A Max T Serge Y A | | 0，，： | 1 |
| 5 | Segmented polynomial regression applied to taper equations显示文摘 | Max T A Burkhart H E | 1976 | Forest Science1976，22，： | 1 |
| 6 | Influence of cultivar, maturity storage and storage conditions on phenolic composition and enzymatic browining of pear fruits显示文摘 | Marie J A Max T Serge Y A | 1995 | Agric Food Chem1995，43，： | 1 |
| 7 | Flareless ethylene plant 显示文摘 | Max Dale A Jones Sidney T | 1983 | Hydrocarbon Processing1983，62，12： | 1 |
| 8 | Stand structure in eastside old-growth ponderosa pine forests of Oregon and northern California 显示文摘 | Youngblood A Max T Coe K | 2004 | For Ecol & Manage2004，199，2： | 1 |
| 9 | Segmented polynomial regression applied to taper equations显示文摘 | MAX T A BURKHART H E | 1976 | Forest Sci1976，22，： | 1 |
| 10 | Micromechanical analysis of composite corrugated-core sandwich panels for integral thermal protection systems 显示文摘 | Oscar A Martinez Bhavani V Sankar Raphael T Haftka Satish K Bapanapalli Max L Blosser | 2007 | American Institute of Aeronautics and Astronautics Journal ( AIAA Journal)2007，45，9： | 1 |
| 11 | Effect of implant design and endplate preparation on the compressive strength of interbody fusion constructs显示文摘 | Thomas S Anthony T Max A | 2000 | Spine2000，25，： | 1 |
| 12 | Stand structure in eastside old-growth ponderosa pine forests of Oregon and northern California显示文摘 | Youngblood A Max T Coe K | 2004 | Forest Ecology and Management2004，199，： | 1 |
| 13 | Identification and characterization of human mitochondrial tryptophanyl-tRNA synthetase 显示文摘 | Rene Jcrgensen Max M T Scgaard A | 2000 | Biol Chem2000，275，16： | 1 |
| 14 | Segmented polynomial regression applied to taper equations显示文摘 | MAX T A BURKHART H E | 1976 | Forest Science1976，22，： | 1 |
| 15 | Segmented polynomial regression applied to taper equations 显示文摘 | MAX T A BURKHART H E | 1976 | Forest Science1976，22，： | 1 |
| 16 | Segmented polynomial regression applied to taper equations 显示文摘 | Max T A Burkhart H E | 1976 | Forest Science1976，22，3： | 1 |
| 17 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences显示文摘 | STRAUSBERG R L FEINGOLD E A GROUSE L H DERGE J G KLAUSNER R D COLLINS F S WAGNER L SHENMEN C M SCHULER G D ALTSCHUL S F ZEEBERG B BUETOW K H SCHAEFER C F BHAT N K HOPKINS R F JORDAN H MOORE T MAX S I WANG J HSIEH F DIATCHENKO L MARUSINAK FARMER A A RUBIN G M HONG L STAPLETON M SOARES M B BONALDO M F CASAVANT T L SCHEETZ T E BROWNSTEIN M J USDIN T B TOSHIYUKI S CARNINCI P PRANGE C RAHA S S LOQUELLANO N A PETERS G J ABRAMSON R D MULLAHY S J BOSAK S A MCEWAN P J MCKERNAN K J MALEK J A GUNARATNE P H RICHARDS S WORLEY K C HALE S GARCIA A M GAY L J HULYK S W VILLALON D K MUZNY D M SODERGREN E J LU X GIBBS R A FAHEY J KETTEMAN M MADAN A RODRIGUES S SANCHEZ A WHITING M YOUNG A C SHEVCHENKO Y BOUFFARD G G BLAKESLEY R W TOUCHMAN J W GREEN E D DICKSON M C RODRIGUEZ A C GRIMWOOD J SCHMUTZ J MYERS R M BUTTERFIELD Y S KRZYWINSKI M I SKALSKA U SMAILUS D E SCHNERCH A SCHEIN J E JONES S J MARRA M A | 2002 | Proc Natl Acad Sci USA2002，99，16： | 1 |
| 18 | Effect of soil temperature on root and shoot growth and on budburst timing in conifer seedling transplants显示文摘 | Lopushinsky W Max T A | 1990 | New Forests1990，4，2： | 1 |
| 19 | Flareless ethylene plant显示文摘 | Max D A Jones S T | 1983 | Hydrocarbon Process1983，62，12： | 1 |
| 20 | Influence of cultivar,maturity storage,and storage conditions on phenolic composition and enzymatic browning of pear fruits显示文摘 | Max T Serge Y A | 1995 | J Agric Food Chem1995，，43： | 1 |
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