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| 1 | Pancreaticoduodenectomy in patients ≥ 75 years of age:Are there any differences with other age ranges in oncological and surgical outcomes? Results from a tertiary referral center显示文摘AIM To compare surgical and oncological outcomes after pancreaticoduodenectomy(PD) in patients ≥ 75 years of age with two younger cohorts of patients. METHODS The prospectively maintained Institutional database of pancreatic resection was queried for patients aged ≥ 75 years(late elderly, LE) submitted to PD for any disease from January 2010 to June 2015. We compared clinical, demographic and pathological features and survival outcomes of LE patients with 2 exact matched cohorts of younger patients [≥ 40 to 64 years of age(adults, A) and ≥ 65 to 74 years of age(young elderly, YE)] submitted to PD, according to selected variables. RESULTS The final LE population, as well as the control groups, were made of 96 subjects. Up to 71% of patients was operated on for a periampullary malignancy and pancreatic cancer(PDAC) accounted for 79% of them. Intraoperative data(estimated blood loss and duration of surgery) did not differ among the groups. The overall complication rate was 65.6%, 61.5% and 58.3% for LE, YE and A patients, respectively, P = NS). Reoperation and cardiovascular complications were significantly more frequent in LE than in YE and A groups(P = 0.003 and P = 0.019, respectively). When considering either all malignancies and PDAC only, the three groups did not differ in survival. Considering all benign diseases, the estimated mean survival was 58 and 78 mo for ≥ and < 75 years of age(YE + A groups), respectively(P = 0.012). CONCLUSION Age is not a contraindication for PD. A careful selection of LE patients allows to obtain good surgical and oncological results. | Salvatore Paiella Matteo De Pastena Tommaso Pollini Giovanni Zancan Debora Ciprani Giulia De Marchi Luca Landoni Alessandro Esposito Luca Casetti Giuseppe Malleo Giovanni Marchegiani Massimiliano Tuveri Enrico Marrano Laura Maggino Erica Secchettin Deborah Bonamini Claudio Bassi Roberto Salvia | 2017 | World Journal of Gastroenterology2017，23，17： | 2 |
| 2 | Targeted next‐generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas显示文摘 | Eliana Amato Marco dal Molin Andrea Mafficini Jun Yu Giuseppe Malleo Borislav Rusev Matteo Fassan Davide Antonello Yoshihiko Sadakari Paola Castelli Giuseppe Zamboni Anirban Maitra Roberto Salvia Ralph H Hruban Claudio Bassi Paola Capelli Rita T Lawlor Mi | 2014 | J. Pathol2014，，3： | 2 |
| 3 | HP-NAP inhibits the growth of bladder cancer in mice by activating a cytotoxic Th1 response显示文摘 | Gaia Codolo Matteo Fassan Fabio Munari Andrea Volpe Piefrancesco Bassi Massimo Rugge Francesco Pagano Mario Milco D’Elios Marina Bernard | 2012 | Cancer Immunology Immunotherapy2012，，1： | 2 |
| 4 | Efficacy of an Absorbable Fibrin Sealant Patch (TachoSil) After Distal Pancreatectomy: A Multicenter, Randomized, Controlled Trial显示文摘 | Marco Montorsi Alessandro Zerbi Claudio Bassi Lorenzo Capussotti Roberto Coppola Matteo Sacchi | 2012 | Annals of Surgery2012，，5： | 1 |
| 5 | Optimal contracting with altruism and reciprocity 显示文摘 | Matteo Bassi Marco Pagnozzi Salvatore Piccolo | 2014 | Research in Economics2014，68，： | 1 |
| 6 | HP-NAP inhibits the growth of bladder cancer in mice by activating a cytotoxic Th1 response显示文摘 | Gaia Codolo Matteo Fassan Fabio Munari Andrea Volpe Piefrancesco Bassi Massimo Rugge Francesco Pagano Mario Milco D’Elios Marina Bernard | 2012 | Cancer Immunology Immunotherapy2012，，1： | 1 |
| 7 | Consumer attitudes towards the mountain product label: Implications for mountain development显示文摘To protect and promote the originality and authenticity of mountain foodstuffs, the European Union set Regulation No 1151/2012 to create the optional quality term 'mountain product'. Our research aimed at exploring the attractiveness of the mountain product label for consumers, considering both attitude towards the label itself and purchase intentions. We propose a model to investigate relationships between four latent constructs-mountain attractiveness, mountain food attractiveness, attitude towards the mountain product label, and purchase intention-which have been tested, thus confirming the statistical relevance of the relationships. All 47 items selected for describing the latent constructs are suitable for this purpose. Ridge and LASSO results also show that 17 items of the first three constructs are relevant in explaining purchase intentions. Some contextual variables, such as age, income, geographical origin of consumers, and knowledge of mountain products and mountains for tourism purposes, can positively influence consumers’ behavior. These findings could support the design of mountain development strategies, in particular marketing actions for both the product and the territory. | BASSI Ivana CARZEDDA Matteo GRASSETTI Luca ISEPPI Luca NASSIVERA Federico | 2021 | Journal of Mountain Science2021，18，9： | 0 |
| 8 | Integration of Carbon Assimilation Modes with Photosynthetic Light Capture in the Green Alga Chlamydomonas reinhardtii显示文摘单细胞的绿水藻 Chlamydomonas reinhardtii 能够同时使用器官、无机的碳来源,它要求 photosyntheticactivity 的调整到碳吸收的占优势的模式。我们获得了新奇卓见进跟随改变的碳来源可获得性的 light-harvestingat photosystem II (PSII ) 的规定。在 C。reinhardtii,联系 PSII 的轻收获的蛋白质(LHCBM ) 的合成被 cytosolic 控制 RNA 有约束力的蛋白质 NAB1,它镇压特别 LHCBM isoform 抄本的翻译。当线性光合的电子流动被公司 2-limitation 在 photoheterotrophic 上下文限制时,这机制经由 nuclearNAB1 倡导者的规定被调整,它被激活。在里面野类型, NAB1 的累积减少功能的 PSII 天线尺寸,因此阻止 PSII 的一个有害过于激动的状态,,观察了在一 NAB1 少些变异。当对延长公司 2-limitation 的最新识别的长期的回答作为对 PSII 在刺激上的快回答代替 LHCII 州的转变,我们进一步表明那 translationcontrol。有趣地, long-termresponse 的激活在州的转变异种 stt7 被使不安,建议在长期、短期的反应之间的一个规章的连接。我们描绘操作 distincttimescales 的一个规章的电路并且在不同细胞的分隔空间调整在 photoheterotrophic 优核质轻收获。 | Hanna Bergera Olga Blifernez-Klassen Matteo Ballottari Roberto Bassi Lutz Wobbe Olaf Kruse | 2014 | Molecular Plant2014，7，10： | 0 |
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