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| 1 | Liver Nuclear Activation of Carbon Tetrachloride or Bromotrichloromethane to Trichloromethyl and Trichloromethylperoxyl Free Radicals.Their Reactions With Lipids and Proteins显示文摘The formation of·CCl3 radicals in liver nuclei was suggested by spin trapping of them with N-t-butyl-α-phenylnitrone followed by GC/MS detection of the resulting adduct. Comparison of its formation in microsomal biotransformation of CCl4 was made. In aerobic nuclear activation mixtures containing NADPH and CCl4, significant decrease in the arachidonic acid content of nuclear lipids was observed (27. 8%, compared to control), the intensity of this decrease was lower than that occurring in the corresponding microsomal incubation mixtures (29.1%). Significant decreases in arachidonic acid content of nuclear and endoplasmic reticulum lipids were also observed in animals at 6 hours of poisoning with the haloalkane. During aerobic nuclear metabolism of CCl4 or CBrCl3, cholesterol oxidation products were detected: a ketocholesterol, an epoxide like structure and 7-ketocholesterol. Nuclear protein carbonyl formation was not promoted during nuclear CCl4 biotransformation. NADPH by itself may lead to protein carbonyl formation during prolonged periods of incubation. CBrCl3 in contrast, led to decreased protein carbonyl formation. No increase in nuclear protein carbonyl formation was observed in CCl4 intoxicated animals during periods of time between 1 to 6 hours after treatment. The results indicate that during nuclear biotransformation of CCl4 or CBrCl3 reactive free radicals, PUFA degradation, reactive aldehydes and cholesterol oxidation products are formed, nearby DNA and regulatory proteins. | S. L. FANELLI G. D. CASTRO M. E. GALELLI AND J. A. CASTRO (Centro de Investigaciones Toxicologicas(CEITOX)-CITEFA/CONICET, Zufriategui 4380, 1603 Villa Martelli,Buenos Aires, Argentina)(Send correspondence to Dr. Jose Alberto Castro, Zufriategui 4380, 1 | 1998 | Biomedical and Environmental Sciences1998，11，2： | 4 |
| 2 | Haploidentical ‘megadose' CD+34 cell transplants for patients with acute leukemia 显示文摘 | Martelli MF Reisner Y | 2002 | Leukemia2002，16，： | 3 |
| 3 | Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance显示文摘 | James A. McCubrey Linda S. Steelman William H. Chappell Stephen L. Abrams Ellis W.T. Wong Fumin Chang Brian Lehmann David M. Terrian Michele Milella Agostino Tafuri Franca Stivala Massimo Libra Jorg Basecke Camilla Evangelisti Alberto M. Martelli Richard | 2006 | BBA - Molecular Cell Research2006，，8： | 3 |
| 4 | Intrahepatic cholangiocarcinoma and hepatitis C and B virus infection, alcohol intake, and hepatolithiasis: a case–control study in Italy显示文摘 | Francesco Donato Umberto Gelatti Alessandro Tagger Maurizio Favret Maria Lisa Ribero Francesco Callea Claudia Martelli Antonella Savio Paola Trevisi Giuseppe Nardi | 2001 | Cancer Causes and Control2001，，10： | 3 |
| 5 | Videothoracoscopic management of the solitary pulmonary nodule: a single-institution study on 429 cases显示文摘 | Giuseppe Cardillo Mohamed Regal Francesco Sera Marco Di Martino Luigi Carbone Francesco Facciolo Massimo Martelli | 2003 | The Annals of Thoracic Surgery2003，，5： | 2 |
| 6 | Foveavirus, a new plant virus genus显示文摘 | G.P. Martelli W. Jelkmann | 1998 | Archives of Virology1998，，6： | 2 |
| 7 | 超越想像的生活空间 印度普纳Yoo设计酒店显示文摘举世闻名的设计大师菲利普·斯塔克(Philippe Starck)和极富远见的开发商约翰·希契考克斯(John Hitchcox)最近携手共创了一个新的设计酒店品牌——Yoo。Yoo的主要理念非常简单,创造不同凡响的、多功能的、超越想像的生活空间。 | Philippe Starck Samuele Martelli 许科 | 2011 | 室内设计与装修2011，，5： | 2 |
| 8 | Scoping review on vector-borne diseases in urban areas:transmission dynamics,vectorial capacity and co-infection显示文摘Background:Transmission dynamics,vectorial capacity,and co-infections have substantial impacts on vector-borne diseases(VBDs)affecting urban and suburban populations.Reviewing key factors can provide insight into priority research areas and offer suggestions for potential interventions.Main body:Through a scoping review,we identify knowledge gaps on transmission dynamics,vectorial capacity,and co-infections regarding VBDs in urban areas.Peer-reviewed and grey literature published between 2000 and 2016 was searched.We screened abstracts and full texts to select studies.Using an extraction grid,we retrieved general data,results,lessons learned and recommendations,future research avenues,and practice implications.We classified studies by VBD and country/continent and identified relevant knowledge gaps.Of 773 articles selected for full-text screening,50 were included in the review:23 based on research in the Americas,15 in Asia,10 in Africa,and one each in Europe and Australia.The largest body of evidence concerning VBD epidemiology in urban areas concerned dengue and malaria.Other arboviruses covered included chikungunya and West Nile virus,other parasitic diseases such as leishmaniasis and trypanosomiasis,and bacterial rickettsiosis and plague.Most articles retrieved in our review combined transmission dynamics and vectorial capacity;only two combined transmission dynamics and co-infection.The review identified significant knowledge gaps on the role of asymptomatic individuals,the effects of co-infection and other host factors,and the impacts of climatic,environmental,and socioeconomic factors on VBD transmission in urban areas.Limitations included the trade-off from narrowing the search strategy(missing out on classical modelling studies),a lack of studies on co-infections,most studies being only descriptive,and few offering concrete public health recommendations.More research is needed on transmission risk in homes and workplaces,given increasingly dynamic and mobile populations.The lack of studies on co-infection hampers monitoring of infections transmitted by the same vector.Conclusions:Strengthening VBD surveillance and control,particularly in asymptomatic cases and mobile populations,as well as using early warning tools to predict increasing transmission,were key strategies identified for public health policy and practice. | Marcus Eder Fanny Cortes Noemia Teixeira de Siqueira Filha Giovanny Vinicius Araujo de Franca Stephanie Degroote Cynthia Braga Valery Ridde Celina Maria Turchi Martelli | 2018 | Infectious Diseases of Poverty2018，7，1： | 2 |
| 9 | Raney镍催化下生物活性化合物的微波辅助脱硫反应显示文摘微波辅助脱硫反应具有反应速度快、收率高等优点,已成为一种有效的脱硫方法,在生物活性化合物的合成中将得到越来越广泛的应用.以乙醇为溶剂,通过微波辅助还原相应苯硫基取代的前体化合物,制备了一系列具有显著生物活性的化合物. | PANUNZIO,Mauro BANDINI,Elisa D'AURIZIO,Antonio MARTELLI,Giorgio TAMANINI,Emiliano 肖尚友 夏之宁 | 2008 | 有机化学2008，28，1： | 2 |
| 10 | Photoluminescence of CdSe Nanowires Grown With and Without Metal Catalyst显示文摘我们 CdSe nanowires 上的现在的温度和力量依赖者光致发光大小有或没有金属催化剂的使用经由蒸汽阶段综合了。没有催化剂,生产的 Nanowires 能被优化产出更高的量效率,和更狭窄、空间地一致的排放,当时与帮助催化剂的相比。在比乐队边低的精力的排放也在两个盒子中被发现。由在一样的 nanowires 上联合空间地解决的光致发光和电子显微镜学,我们证明没有催化剂的 nanowires 与锋利的声子复制品展出一座低精力的山峰,而为帮助催化剂的 nanowires 低精力的排放与扩大词法缺点被连接到 nanostructures 的存在。 | Andrea Fasoli Alan Colli Faustino Martelli Simone Pisana Ping Heng Tan Andrea C. Ferrari | 2011 | Nano Research2011，4，4： | 2 |
| 11 | Localized (solitary) fibrous tumors of the pleura: an analysis of 55 patients显示文摘 | Giuseppe Cardillo Francesco Facciolo Andrea O Cavazzana Girolamo Capece Roberto Gasparri Massimo Martelli | 2000 | The Annals of Thoracic Surgery2000，，6： | 2 |
| 12 | Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia显示文摘 | Andrea Caporali Marco Meloni Christine V?llenkle Desiree Bonci Graciela B. Sala-Newby Roberta Addis Gaia Spinetti Sergio Losa Rachel Masson Andrew H. Baker Reuven Agami Carlos le Sage Gianluigi Condorelli Paolo Madeddu Fabio Martelli Costanza Emanueli | 2011 | Circulation2011，，3： | 2 |
| 13 | Serological detection of grapevine rupestris stem pitting-associated virus (GRSPaV) by a polyclonal antiserum to recombinant virus coat protein 显示文摘 | MINAFRA A CASATI P ELICIO V ROWHANI A SALDARELLI P SAVINO V MARTELLI G P | 2000 | Vitis2000，39，3： | 1 |
| 14 | Homocysteine Modulates the CD40/CD40L System 显示文摘 | Cesaria Prontera Nicola Martelli Virgilio Evangelista | 2007 | J Am Coll Cardiol2007，49，： | 1 |
| 15 | Cellular therapy: exploiting NK cell alloreactivity in transplantation显示文摘 | Ruggeri L Capanni M Martelli MF | 2001 | Curt Opin Hematol2001，8，6： | 1 |
| 16 | Magnetic field and shock effects and remanent magnetization in a hypervelocity impact experiment显示文摘 | Srnka L J Martelli G Newton G | 1979 | Earth and Planetary Science Letters1979，42，1： | 1 |
| 17 | Safety of dipeptidyl peptidase-4 inhibitor: a meta-analysis of randomized clinical trials显示文摘 | MONAMI M DICEMBRINI I MARTELLI D | 2011 | Curt' Med Res Opin2011，273，： | 1 |
| 18 | A first comparative map of copy number variations in the sheep genome显示文摘 | Fontanesi L Beretti F Martelli P L | 2011 | Genomics2011，97，： | 1 |
| 19 | Does ACL reconstruction restore knee stability in combined lesions:An in vivo study显示文摘 | Zaffagnini S Bignozzi S Martelli S | | 0，，： | 1 |
| 20 | Influence of the glycerol concentration on some physical properties of feather keratin films显示文摘 | MOORE G R MARTELLI S M GANDOLFO C | 2006 | FoodHydrocolloids2006，20，7： | 1 |
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