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| 1 | Experimental assessment and prediction of temporal scour depth around a spur dike显示文摘Spur dikes are river training structures that have been extensively used worldwide for towards enhancing flood control and the stability of embankments and riverbanks.However,scour around spur dikes can be a major problem affecting their stability and hydraulic performance.The precise computation of temporal scour depth at spur dikes is very important for the design of economical and safe spur dikes.This study focuses on experimentally assessing the temporal variation of scour depth around a vertical wall spur dike and identifying the parameters,which mostly influence spur dike performance for a channel bed surface comprised of sand-gravel mixtures.In the current study,the authors did physical experiments in a flume based study to obtain new data,aimed at deriving a new predictive model for spur dike scour and comparing its performance to others found in the literature.It was found that the dimensionless temporal scour depth variation increases with an increase in(i)the threshold velocity ratio,(ii)the densimetric Froude number of the bed surface sediment mixture,(iii)the flow shallowness(defined as the ratio of the approach flow depth,y,to the spur dike’s transverse length,l),and(iv)the flow depth-particle size ratio.It is also concluded that the temporal scour depth variation in the sediment mixture is influenced by the non-uniformity of sediment and decreases with an increase in the non-uniformity of the sediment mixture.A new mathematical model is derived for the estimation of temporal scour depths in sand-gravel sediment mixtures.The proposed equation has been calibrated and validated with the experimental data,demonstrating a good predictive capacity for the estimation of temporal scour depth evolution. | Manish Pandey Manousos Valyrakis Meilan Qi Anurag Sharma Ajay Singh Lodhi | 2021 | International Journal of Sediment Research2021，36，1： | 8 |
| 2 | Surgical treatment of hepatic metastases from colorectal cancer显示文摘Colorectal carcinoma is one of the most frequent cancers in Western societies with an incidence of around 700 per million people.About half of the patients develop metastases from the primary tumor and liver is the primary metastatic site.Improved survival rates after hepatectomy for metastatic colorectal cancer have been reported in the last few years and these may be the result of a variety of factors,such as advances in systemic chemotherapy,radiographic imaging techniques that permit more accurate determination of the extent and location of the metastatic burden,local ablation methods,and in surgical techniques of hepatic resection.These have led to a more aggressive approach towards liver metastatic disease,resulting in longer survival.The goal of this paper is to review the role of various forms of surgery in the treatment of hepatic metastases from colorectal cancer. | Georgios Tsoulfas Manousos Georgios Pramateftakis Ioannis Kanellos | 2011 | World Journal of Gastrointestinal Oncology2011，3，1： | 7 |
| 3 | Molecular markers(PECAM-1,ICAM-3,HLA-DR)determine prognosis in primary non-Hodgkin's gastric lymphoma patients显示文摘瞄准:与主要 non-Hodgkin 的胃的淋巴瘤在病人调查 PECAM-1, ICAM-3 和 HLA 医生抗原的预示的意义。方法:我们免疫组织化学地在 36 个 B 房间麦芽类型主要胃的淋巴瘤病人学习了 PECAM-1, ICAM-3 和 HLA 医生抗原表示。十非恶意并且十个健康胃的织物标本被用作控制。Clinicopathological 和幸存数据与染色的结果被相关。结果:HLA 医生抗原表示在 33 个胃的淋巴瘤病人(91.7%) 和 6 个非恶意的病人(54.5%) 被检测。PECAM-1 染色了 10 个病人(27.8%) 的肿瘤房间, 9 个病人(25%) 的 endothelial 并且煽动性有良性的胃的疾病的 4 个病人(40%) 渗入。ICAM-3 表示在 17 个病人(47.2%) 的肿瘤房间上被观察,当 5 个非恶意的病人(50%) 被染色时积极也。任何一个都没为任何学习的基因健康控制被染色。在里面多,变量分析, HLA 医生抗原和 PECAM-1 被证明是与联系的统计上重要的独立预示的因素一赞成并且不利预后分别地(P=0.009 和 P=0.003 ) 。在 univariate 分析, PECAM-1 (+)/ICAM-3 (-) 和 HLA 医生(-)/ICAM-3 (-) 病人与确切相反的基因表示模式与那些相比展出了显著地减少的全面幸存(P=0.0041 和 P=0.0091,分别地) 。是 HLA 医生(+)/ICAM-3 (+)/PECAM-1 (-)(n=8 ) 的那些病人让显著地更高的幸存与这个组(n=24 )(P=0.0289 ) 的其余部分相比评价。结论:PECAM-1, ICAM-3 和 HLA 医生分别地是肿瘤扩大潜力和主人免疫者监视的代表性的标记。他们的联合使用可以帮助我们识别能得益于更好攻击的治疗学的协议的高风险的病人。 | Alexander Darom Ilias P Gomatos Emmanuel Leandros Emmu Chatzigianni Dimitris Panousopoulos Manousos M Konstadoulakis George Androulakis | 2006 | World Journal of Gastroenterology2006，12，12： | 4 |
| 4 | Atypical anastomotic malignancies of small bowel after subtotal gastrectomy with BillorthⅡgastroenterostomy for peptic ulcer:Report of three cases and review of the literature显示文摘AIM To present patients who developed small-bowel malignancy at the level of the gastrointestinal anastomosis decades after a subtotal gastrectomy for ulcer,to review relevant literature,and to attempt to interpret the reasons those cancers developed to these postsurgical non-gastric sights.METHODS For the current retrospective study and review of literature,the surgical and histopathological records dated from January 1,1993 to December 31,2017 of our department were examined,searching for patients who have undergone surgical treatment of small-bowel malignancy to identify those who have undergone subtotal gastrectomy for benign peptic ulcer.A systematic literature search was also conducted using Pub Med,EMBASE,and Cochrane Library to identify similar cases.RESULTS We identified three patients who had developed smallintestine malignancy at the level of the gastrointestinal anastomosis decades after a subtotal gastrectomy with Billroth Ⅱ gastroenterostomy for benign peptic ulcertwo patients with adenocarcinoma originated in the Braun anastomosis and one patient with lymphoma of the efferent loop.All three patients were submitted to surgical resection of the tumor with Roux-en-Y reconstruction of the digestive tract.In the literature review,we only found one case of primary small-intestinal cancer that originated in the efferent loop after Billroth Ⅱ gastrectomy because of duodenal ulcer but none reporting Braun anastomosis adenocarcinoma following partial gastrectomy for benign disease.We also did not find any case of efferent loop lymphoma following gastrectomy.CONCLUSION Anastomotic gastric cancer following distal gastrectomy for peptic ulcer is a well-established clinical entity.However,malignancies of the afferent or efferent loop of the gastrointestinal anastomosis are extremely uncommon.The substantial diversion of the potent carcinogenic pancreaticobiliary secretions through the Braun anastomosis and the stomach hypochlorhydria,allowing the formation of carcinogenic factors from food,are the two most prominent pathogenetic mechanisms for those tumors. | Efstathios Kotidis Orestis Ioannidis Manousos George Pramateftakis Konstantinos Christou Ioannis Kanellos Konstantinos Tsalis | 2018 | World Journal of Gastrointestinal Oncology2018，10，7： | 4 |
| 5 | Chemical characterisation of particulate matter in urban transport modes显示文摘Traffic is a main source of air pollutants in urban areas and consequently daily peak exposures tend to occur during commuting.Personal exposure to particulate matter(PM)was monitored while cycling and travelling by bus,car and metro along an assigned route in Lisbon(Portugal),focusing on PM_(2.5) and PM_(1)0(PM with aerodynamic diameter<2.5 and 10μm,respectively)mass concentrations and their chemical composition.In vehicles,the indoor-outdoor interplay was also evaluated.The PM_(2.5) mean concentrations were 28±5,31±9,34±9 and 38±21μg/m 3 for bus,bicycle,car and metro modes,respectively.Black carbon concentrations when travelling by car were 1.4 to 2.0 times higher than in the other transport modes due to the closer proximity to exhaust emissions.There are marked differences in PM chemical composition depending on transport mode.In particular,Fe was the most abundant component of metro PM,derived from abrasion of rail-wheel-brake interfaces.Enhanced concentrations of Zn and Cu in cars and buses were related with brake and tyre wear particles,which can penetrate into the vehicles.In the motorised transport modes,Fe,Zn,Cu,Ni and K were correlated,evidencing their common traffic-related source.On average,the highest inhaled dose of PM_(2.5) was observed while cycling(55μg),and the lowest in car travels(17μg).Cyclists inhaled higher doses of PM_(2.5) due to both higher inhalation rates and longer journey times,with a clear enrichment in mineral elements.The presented results evidence the importance of considering the transport mode in exposure assessment studies. | Vania Martins Carolina Correia Ines Cunha-Lopes Tiago Faria Evangelia Diapouli Manousos Ioannis Manousakas Konstantinos Eleftheriadis Susana Marta Almeida | 2021 | Journal of Environmental Sciences2021，33，2： | 2 |
| 6 | Secretome proteomics for discovery of cancer biomarkers显示文摘 | Manousos Makridakis Antonia Vlahou | 2010 | Journal of Proteomics2010，，12： | 2 |
| 7 | Somatostatin for acute severe bleeding from portal hypertensive gastropathy显示文摘 | Kouroumalis EA Koutroubakis IE Manousos ON | 1998 | Eur J Gastroenterol Hepatol1998，10，： | 1 |
| 8 | IGF-I and IGF-II in relation to colorectal cancer显示文摘 | Manousos O Souglakos J Bosetti C | 1999 | Int J Cancer1999，83，1： | 1 |
| 9 | Clinical patterns of Crohn's disease in Greece: a follow-up study of 155 cases显示文摘 | EMMANOUILIDIS A MANOUSOS O | 2000 | Digestion2000，61，2： | 1 |
| 10 | Anastomotic leakage after low anterior resection for rectal cancer:faels,oseurity,and fiction 显示文摘 | Panagiotis T Manousos C Dimitrios DT | 2009 | Surg Today2009，39，2： | 1 |
| 11 | IGF-Ⅰ and IGF-Ⅱ in relation to colorectal cancer显示文摘 | Manousos O Souglakos J Bosetti C | | 0，，01： | 1 |
| 12 | Defense mechanisms in inflammatory bowel disease显示文摘 | Thomas N. Hyphantis John K. Triantafillidis Sofia Pappa Christos Mantas Anna Kaltsouda Peter Cherakakis Yannis Alamanos Orestis N. Manousos Venetsanos G. Mavreas | 2005 | Journal of Gastroenterology2005，，1： | 1 |
| 13 | Clinical pattens of Crohn's disease in Creece:a follow-up study of 155cases显示文摘 | TRIANTAFILLIDIS J K EMMANOUILIDIS A MANOUSOS O | 2000 | Digestion2000，61，2： | 1 |
| 14 | Clinical trials update-The heart protection study,Iona,Carisa enriched,acute,alive,maditⅡ,and rematch显示文摘 | Louis AA Manousos IR Coletta AP | 2002 | Eur J Heart Fail2002，4，： | 1 |
| 15 | Somatostatin for acute severe bleeding from portal hypertensive gastropathy显示文摘 | Kourounmalis EA Koutroubakis IE Manousos ON | 1998 | Eur J Gastroenterol Hepiatol1998，10，： | 1 |
| 16 | Anastomotic leakage after low anterior resection for rectal cancer: Facts, obscurity, and fiction显示文摘 | Panagiotis Taflampas Manousos Christodoulakis Dimitrios D. Tsiftsis | 2009 | Surgery Today2009，，3： | 1 |
| 17 | Somatostatin for acute severe bleeding from portal hypertensive gastropathy显示文摘 | Kouroumalis EA Koutroubakis IE Manousos ON | 1998 | Eur J Gastroenterol Hepatol1998，10，： | 1 |
| 18 | Marked defects in the expression and glycosylation of α- 2 - HS glycoprotein/fetuin -- A in plasma from neonates with intrauterine growth restriction: Proteomic screening and potential clinical implications 显示文摘 | Panagiotis MK AM Theodora B Manousos M | 2008 | Mol Cell Proteomics2008，7，： | 1 |
| 19 | Natural history of advanced hepatocellular carcinoma in Crete. Association with hepatitis C virus显示文摘 | Elias A. Kouroumalis Panagiotis G. Skordilis Joanna Moschandrea Georgios Alexandrakis Nikolaos Charoulakis Maria Tzardi Orestes N. Manousos | | European Journal of Gastroenterology & Hepatology0，，： | 1 |
| 20 | Somatostatin for acute severe bleeding from portal hypertensive gastropathy 显示文摘 | Kouroumalis EA Koutroubakis IE Manousos ON | 1998 | Eur J Gastroenterol Hepatol1998，10，6： | 1 |
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