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18篇 您的检索式:作者名="Magnolia"
    题名 作者 年代 出处 被引量
1Combined endoscopic treatment for cholelithiasis associated with choledocholithiasis 显示文摘Saccomani G Durante V Magnolia MR 2005Surg Endosc2005,19,7:1
2Combined endoscopic treatment for cholelithiasis associated with choledocholithiasis显示文摘Saccomani G Durante V Magnolia MR 2005Surg Endosc2005,19,7:1
3Combined endoscopic treatment for cholelithiasis associated with choledocholithiasis显示文摘Saccomani G Durante V Magnolia MR 2005Surg Endosc2005,19,7:1
4Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer显示文摘Colorectal cancer(CRC)is the second leading cause of cancer-related death worldwide.The five-year survival rate of CRC patients depends on the stage at diagnosis,being higher than 80%when CRC is diagnosed in the early stages but lower than 10%when CRC is diagnosed in advanced stages.Autoantibodies against specific CRC autoantigens(tumor-associated antigens(TAAs))in the sera of patients have been widely demonstrated to aid in early diagnosis.Thus,we herein aim to identify autoantigens target of autoantibodies specific to CRC that possess a significant ability to discriminate between CRC patients and healthy individuals by means of liquid biopsy.To that end,we examined the protein content of the exosomes released by five CRC cell lines and tissue samples from CRC patients by means of immunoprecipitation coupled with mass spectrometry analysis.A total of 103 proteins were identified as potential autoantigens specific to CRC.After bioinformatics and meta-analysis,we selected 15 proteins that are more likely to be actual CRC autoantigens in order to evaluate their role in CRC prognosis by Western blot(WB)and immunohistochemistry(IHC).We found dysregulation at the protein level for 11 of these proteins in both tissue and plasma exosome samples from patients,along with an association of nine of these proteins with CRC prognosis.After validation,all but one showed a statistically significant high diagnostic ability to distinguish CRC patients and individuals with premalignant lesions from healthy individuals,either by luminescence Halotag-based beads,or by a multiplexed biosensing platform involving the use of magnetic microcarriers as solid support modified with covalently immobilized Halotag fusion proteins constructed for CRC detection.Taken together,our results highlight the usefulness of the approach defined here to identify the TAAs specific to chronic diseases;they also demonstrate that the measurement of autoantibody levels in plasma against the TAAs identified here could be integrated into a point-of-care(POC)device for CRC detection with high diagnostic ability.Ana Montero-Calle Itziar Aranguren-Abeigon María Garranzo-Asensio Carmen Poves María Jesús Fernández-Aceñero Javier Martínez-Useros Rodrigo Sanz Jana Dziaková Javier Rodriguez-Cobos Guillermo Solís-Fernández Eloy Povedano Maria Gamella Rebeca Magnolia Torrente-Rodríguez Miren Alonso-Navarro Vivian de los Ríos J.Ignacio Casal Gemma Domínguez Ana Guzman-Aranguez Alberto Peláez-García JoséManuel Pingarrón Susana Campuzano Rodrigo Barderas 2021Engineering2021,7,10:1
5Thrombocytosis in children显示文摘Chiarello P Magnolia M Rubino M 0,,06:1
6Thrombocy- tosis in children显示文摘CHIARELLO P MAGNOLIA M RUBINO M 2011Minerva Pediatr2011,63,6:1
7Characterising Mycobacterium tuberculosis Rv1510c protein and determining its sequences that specifically bind to two target cell lines显示文摘Ricardo Vera-Bravo Elizabeth Torres John J. Valbuena Marisol Ocampo Luis E. Rodríguez álvaro Puentes Javier E. García Hernando Curtidor Jimena Cortés Magnolia Vanegas Zuly J. Rivera Andrea Díaz Martha N. Calderon Manuel A. Patarroyo Manuel E. Patarroyo 2005Biochemical and Biophysical Research Communications2005,,:1
8Combined endoscopic treatment for cholelithiasis associated with choledocholithiasis显示文摘G. Saccomani V. Durante M. R. Magnolia L. Ghezzo R. Lombezzi L. Esercizio M. Stella A. Arezzo 2005Surgical Endoscopy2005,,7:1
9Combined endoscopic treatment for cholelithiasis associated with choledocholithiasis 显示文摘Saccomani G Durante V Magnolia MR 2005Surg Endosc2005,19,7:1
10Combined endoscop-ic treatment for cholelithiasis associated with choledocholithiasis显示文摘Saccomani G Durante V Magnolia MRe t al 2005Surg Endosc2005,19,:1
11Combined endoscopic treatment for cholelithiasis associated with choledocholithiasis显示文摘Saccomani G Durante V Magnolia MR 2005Surg Endosc2005,19,:1
12Sodium bentonite and monensin under chronic aflatox- icosis in broiler chickens 显示文摘MAGNOLIA P TEXEIRA M ROSS C A R 2011Poultry Science2011,90,2:1
13The SRA methyl-cytosine-binding domain links DNA and histone methylation 显示文摘LIANNA M J MAGNOLIA B STEVEN E J 2007Current Biology2007,17,:1
14Late Pleistocene marine terrace deposits in northeastern Brazil:sea-level change and tectonic implications显示文摘Alcina Magnolia Franca Barreto Francisco Hila 2002Palaeogeography Palaeoclimatology Palaeoecology2002,179,:1
15Combined endoscopic treatment for choletithiasis associated with choledocholithiasis 显示文摘Saccomani G Durante V Magnolia MR 2005Surg Endosc2005,19,7:1
16Combined endo- scopic treatment for cholelithiasis associated with choledochdithia- sis显示文摘Saccomani G Durante V Magnolia MR 2005Surg Endosc2005,19,7:1
17Com- mercial bentonites as detoxifier of broiler feed contaminated with aflatoxin 显示文摘MAGNOLIA P TALLONE L ROSA C A R 2008Appl Clay Sci2008,40,:1
18Thrombolysis With Recombinant Tissue Plasminogen Activator and Tirofiban in Stroke: Preliminary Observations显示文摘Rüdiger J. Seitz Magnolia Hamzavi Ulrich Junghans Peter A. Ringleb Corinna Schranz Mario Siebler 2003Stroke: Journal of the American Heart Association2003,,8:1
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