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| 1 | On the combined effect of soil fertility and topography on tree growth in subtropical forest ecosystems—a study from SE China显示文摘Aims The aim of our research was to understand small-scale effects of topography and soil fertility on tree growth in a forest biodiversity and ecosystem functioning(BEF)experiment in subtropical SE China.Methods Geomorphometric terrain analyses were carried out at a spatial resolution of 5×5 m.Soil samples of different depth increments and data on tree height were collected from a total of 566 plots(667 m2 each).The soils were analyzed for carbon(soil organic carbon[SOC]),nitrogen,acidity,cation exchange capacity(CEC),exchangeable cations and base saturation as soil fertility attributes.All plots were classified into geomorphological units.Analyses of variance and linear regressions were applied to all terrain,soil fertility and tree growth attributes.Important Findings In general,young and shallow soils and relatively small differences in stable soil properties suggest that soil erosion has truncated the soils to a large extent over the whole area of the experiment.This explains the concurrently increasing CEC and SOC stocks downslope,in hollows and in valleys.However,colluvial,carbon-rich sediments are missing widely due to the convexity of the footslopes caused by uplift and removal of eroded sediments by adjacent waterways.The results showed that soil fertility is mainly influenced by topography.Monte-Carlo flow accumulation(MCCA),curvature,slope and aspect significantly affected soil fertility.Furthermore,soil fertility was affected by the different geomorphological positions on the experimental sites with ridge and spur positions showing lower exchangeable base cation contents,especially potassium(K),due to leaching.This geomorphological effect of soil fertility is most pronounced in the topsoil and decreases when considering the subsoil down to 50 cm depth.Few soil fertility attributes affect tree height after 1-2 years of growth,among which C stocks proved to be most important while pH_(KCl)and CEC only played minor roles.Nevertheless,soil acidity and a high proportion of Al on the exchange complex affected tree height even after only 1-2 years growth.Hence,our study showed that forest nutrition is coupled to a recycling of litter nutrients,and does not only depend on subsequent supply of nutrients from the mineral soil.Besides soil fertility,topography affected tree height.We found that especially MCCA as indicator of water availability affected tree growth at small-scale,as well as aspect.Overall,our synthesis on the interrelation between fertility,topography and tree growth in a subtropical forest ecosystem in SE China showed that topographic heterogeneity lead to ecological gradients across geomorphological positions.In this respect,small-scale soil-plant interactions in a young forest can serve as a driver for the future development of vegetation and biodiversity control on soil fertility.In addition,it shows that terrain attributes should be accounted for in ecological research. | Thomas Scholten Philipp Goebes Peter Kühn Steffen Seitz Thorsten Assmann Jürgen Bauhus Helge Bruelheide Francois Buscot Alexandra Erfmeier Markus Fischer Werner Härdtle Jin-Sheng He Keping Ma Pascal A.Niklaus Michael Scherer-Lorenzen Bernhard Schmid Xuezheng Shi Zhengshan Song Goddert von Oheimb Christian Wirth Tesfaye Wubet Karsten Schmidt | 2017 | Journal of Plant Ecology2017，10，1： | 22 |
| 2 | Alcoholic liver disease and hepatitis C:A frequently underestimated combination显示文摘Alcoholic liver disease(ALD) and hepatitis C virus(HCV) infection represent, either alone or in combination, more than two thirds of all patients with liver disease in the Western world.This review discusses the epidemiology and combined impact of ALD and HCV on the progres sion of liver disease.ALD and HCV affect the progres sion of liver disease to liver cirrhosis and hepatocellular carcinoma(HCC) in a synergistic manner.Thus, the risk for HCC increases f ive times with a daily alcohol con sumption of 80 g;in the presence of HCV it is increased 20fold, and a combination of both risk factors leads to a more than 100fold risk for HCC development.Alcohol consumption also decreases the response to interferon treatment which is probably due to a lack of compliance than a direct effect on HCV replication.Several molecu lar mechanisms are discussed that could explain the synergistic interaction of alcohol and HCV on disease progression.They include modulation of the immune response and apoptosis, increased oxidative stress via induction of CYP2E1 and the hepatic accumulation of iron.Thus, both HCV and alcohol independently cause hepatic iron accumulation in > 50% of patients probably due to suppression of the liversecreted systemic iron hormone hepcidin.A better understanding of hepcidin regulation could help in developing novel therapeutic approaches to treat the chronic disease in the future.For now, it can be generally concluded that HCVinfect ed patients should abstain from alcohol and alcoholicsshould be encouraged to participate in detoxification programs. | Sebastian Mueller Gunda Millonig Helmut K Seitz | 2009 | World Journal of Gastroenterology2009，15，28： | 18 |
| 3 | Non-invasive diagnosis of alcoholic liver disease显示文摘Alcoholic liver disease(ALD)is the most common liver disease in the Western world.For many reasons,it isunderestimated and underdiagnosed.An early diagnosis is absolutely essential since it(1)helps to identify patients at genetic risk for ALD;(2)can trigger efficient abstinence namely in non-addicted patients;and(3)initiate screening programs to prevent life-threateningcomplications such as bleeding from varices,spontaneous bacterial peritonitis or hepatocellular cancer.The two major end points of ALD are alcoholic liver cirrhosis and the rare and clinically-defined alcoholic hepatitis(AH).The prediction and early diagnosis of both entities is still insufficiently solved and usually relies on acombination of laboratory,clinical and imaging findings.It is not widely conceived that conventional screeningtools for ALD such as ultrasound imaging or routine laboratory testing can easily overlook ca.40%of manifest alcoholic liver cirrhosis.Non-invasive methods such as transient elastography(Fibroscan),acoustic radiation force impulse imaging or shear wave elastography have significantly improved the early diagnosis of alcoholiccirrhosis.Present algorithms allow either the exclusion or the exact definition of advanced fibrosis stages in ca.95%of patients.The correct interpretation of liver stiffness requires a timely abdominal ultrasound and actual transaminase levels.Other non-invasive methods such as controlled attenuation parameter,serum levels of M30 or M65,susceptometry or breath tests are under current evaluation to assess the degree of steatosis,apoptosis and iron overload in these patients.Liver biopsy still remains an important option to rule out comorbidities and to confirm the prognosis namely for patients with AH. | Sebastian Mueller Helmut Karl Seitz Vanessa Rausch | 2014 | World Journal of Gastroenterology2014，20，40： | 15 |
| 4 | Increased liver stiffness in alcoholic liver disease:Differentiating fibrosis from steatohepatitis显示文摘AIM:To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).METHODS:We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of trans-aminases. RESULTS:Of the serum transaminases,the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant chang-es in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels,we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confi rmed ALD. By ex-cluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort,the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS.CONCLUSION:Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL signif icantly improves the diagnostic accuracy. | Sebastian Mueller Gunda Millonig Lucie Sarovska Stefanie Friedrich Frank M Reimann Maria Pritsch Silke Eisele Felix Stickel Thomas Longerich Peter Schirmacher Helmut Karl Seitz | 2010 | World Journal of Gastroenterology2010，16，8： | 10 |
| 5 | Effect of human autologous serum and fetal bovine serum on human corneal epithelial cell viability,migration and proliferation in vitro显示文摘AIM: To analyze the concentration-dependent effects of autologous serum(AS) and fetal bovine serum(FBS) on human corneal epithelial cell(HCEC) viability, migration and proliferation.METHODS: AS was prepared from 13 patients with nonhealing epithelial defects Dulbecco's modified eagle medium/Ham's F12(DMEM/F12) with 5% FBS, 0.5% dimethyl sulphoxide(DMSO), 10 ng/m L human epidermal growth factor, 1% insulin-transferrin-selenium, then were incubated in serum media: DMEM/F12 supplemented by 5%, 10%, 15% or 30% AS or FBS. HCEC viability was analyzed using cell proliferation kit XTT, migration using a wound healing assay, proliferation by the cell proliferation enzyme-linked immunosorbent assay(ELISA) Brd U kit. Statistical analysis was performed using the generalized linear model, the values at 30% AS or 30% FBS were used as the baselines.RESULTS: HCEC viability was the highest at 30% AS or 15% FBS and the lowest at 10% AS or 30% FBS application. HCEC migration was the quickest through 30% AS or 30% FBS and the slowest through 5% AS or 5% FBS concentrations. Proliferation was the most increased through 15% AS or 5% FBS and the least increased through 30% AS or 30% FBS concentrations. HCEC viability at 10% and 15% AS was significantly worse(P=0.001, P=0.023) compared to baseline and significantly better at 15% FBS(P=0.003) concentrations. HCEC migration was significantly worse(P≤0.007) and HCEC proliferation significantly better(P<0.001) in all concentration groups compared to baseline.CONCLUSION: For the best viability of HCEC 30% AS or 15% FBS, for HCEC migration 30% AS or 30% FBS, for proliferation 15% AS or 5% FBS should be used. Therefore, we suggest the use of 30% AS in clinical practice. | Ming-Feng Wu Tanja Stachon Berthold Seitz Achim Langenbucher Nóra Szentmáry | 2017 | International Journal of Ophthalmology(English edition)2017，10，6： | 7 |
| 6 | Habitat use and diel activity pattern of the Tibetan Snowcock(Tetraogallus tibetanus):a case study using camera traps for surveying high-elevation bird species显示文摘Background:Global climate change has had significant effects on animal distribution and population dynamics in mid-latitude alpine areas,but we know little about the basic ecology of high-altitude species due to the difficulties of conducting field research in the harsh climate and habitat present at high elevations.The Tibetan Snowcock(Tetraogallus tibetanus) is a little-known phasianid distributing in alpine areas at extremely high elevations in the mountains surrounding the Tibetan Plateau.Estimating the species occupancy rate and discussing the factors affecting its distribution based on infrared-triggered camera techniques would provide both a baseline to measure the influence of global warming and valuable information on its conservation and ecology.Methods:We used infrared-triggered cameras to investigate the Tibetan Snowcock on the western slope of Mt.Gongga from June to November 2016.We used the R package 'overlap' to visualize its activity pattern,and used an occupancy model to both examine its habitat use as well as to determine the most influential variables affecting its habitat use.Results:Using 103 camera traps over 9213 camera-days,we recorded 428 instances of Tibetan Snowcock.The diel activity peaks of Tibetan Snowcock occurred during the periods of 8:00-10:00 am and 18:00-20:00 pm.The model estimate of occupancy for Tibetan Snowcock(0.830) was slightly higher than the na?ve site occupancy based on camera detections(0.663),indicating a wider use of habitat than the camera traps recorded.Elevation,slope,settlement density,road density,and EVI(enhanced vegetation index) were the most influential variables for its habitat use.Conclusions:The Tibetan Snowcock is confirmed to be diurnal.This species prefers an environment with a high elevation,gentle slope,and low EVI,apparently facing a trade-off between predator risk,foraging efficiency,and food availability.When human impact was low,there was a positive correlation between the habitat use of the Tibetan Snowcock and both its road and settlement densities.Infrared cameras and proper survey design are valuable for investigating extreme alpine phasianids. | Gai Luo Chuangming Yang Huaming Zhou Michael Seitz Yongjie Wu Jianghong Ran | 2019 | Avian Research2019，10，1： | 6 |
| 7 | Duration and intensity of rainfall events with the same erosivity change sediment yield and runoff rates显示文摘The effect of different rainfall patterns on surface runoff,infiltration and thus soil losses and sediment concentrations are still in the focus of current research.In most simulated rainfall experiments,pre-cipitation is applied at a fixed intensity for a fixed time.However,the impact of rainfall patterns on soil erosion processes may be different varying the rainfall duration and intensity that produces an event with similar rainfall erosivity values.Twenty-five rainfall events were applied on micro-scale runoff plots in a soil covered with corn straw to evaluate the sediment yield and runoff rates.The different rainfall types were composed by association of duration(Dur)and intensity(IP)with the same erosivity value.The Dur varied from 38 to 106 min and the IP varied from 75.0 to 44.6 mm h^(-1).The sediment yield varied from 1.89±1.26 g m^(-2) to 4.02±2.66 g m^(-2) and runoff ranged from 16.9±8.74 mm to 32.63±10.67 mm with highest rates occurring with high intensity and low duration.The highest rainfall intensity provides the maximum sediment yield(0.138 g m^(-2) min^(-1))and runoff rates(0.87 mm min^(-1)).The time to start surface runoff varied from 14 to 19.2 min and it was longer in treatments with longer durations and low precipitation intensity.No difference was found in the amount of sediments applying rain with the same erosivity and different associations of duration and intensity.However,the intensity and duration of the rain,with the same erosivity,altered the amount and time of runoff.In rainfall experiments with con-stant intensity and fixed time,the erosion rates depend on the duration of the applied rain.Therefore,the results of this study can contribute to the development of new perspectives in the design of water erosion experiments with simulated rain considering the duration,intensity and also the association of these variables to produce rainfall that delivery the same soil erosion capacity. | Wilk Sampaio de Almeida Steffen Seitz Luiz Fernando Coutinho de Oliveira Daniel Fonseca de Carvalho | 2021 | International Soil and Water Conservation Research2021，9，1： | 4 |
| 8 | Photo tourism显示文摘 | Noah Snavely Steven M. Seitz Richard Szeliski | 2006 | ACM Transactions on Graphics (TOG)2006，，3： | 3 |
| 9 | Letting Go is Never Easy:Abscission and Receptor- Like Protein Kinases显示文摘Abscission is the process by which plants discard organs in response to environmental cues/stressors,or as part of their normal development.Abscission has been studied throughout the history of the plant sciences and in numerous species.Although long studied at the anatomical and physiological levels,abscission has only been elucidated at the molecular and genetic levels within the last two decades,primarily with the use of the model plant Arabidopsis thaliana.This has led to the discovery of numerous genes involved at all steps of abscission,including key pathways involving receptor-like protein kinases(RLKs).This review covers the current knowledge of abscission research,highlighting the role of RLKs. | Chad E.Niederhuth Sung Ki Cho Kati Seitz John C.Walker | 2013 | Journal of Integrative Plant Biology2013，55，12： | 3 |
| 10 | 圆锥角膜穿透性角膜移植术后缝线相关的角膜规则程度的动态变化显示文摘目的分析圆锥角膜(KC)手术前后角膜规则程度的变化,以及角膜缝线拆除对角膜规则程度的影响,对激光穿透性角膜移植手术(PK)在KC治疗中的作用进行评价。方法回顾分析了236例圆锥角膜使用激光环钻技术进行的穿透性角膜移植手术手术,使用角膜曲率计(Ophthalmometer,Type-H,190071Zeiss,Jena,Germany)对手术前后的角膜规则程度进行检测,并结合所测出的角膜曲率(K)值和角膜映光图像分成4组:(0)规则组,K〈50D;(1)轻度不规则组,K〈60;(2)中度不规则组,K≥60;(3)重度不规则组,K值不能读出,共4组。手术后第12、18个月依次拆除连续缝线,并同时随访记录各组别角膜规则程度,动态分析以上三个时间点角膜规则程度的变化特点。结果在三个时间点,规则组比例的递增趋势为4%-37%-61%轻度不规则组的变化趋势为12%-51%-33‰中度不规则组的递减趋势为38%-10%-4%;重度不规则组的变化趋势为46%-2%-2%。结论使用激光环钻和16针双线连续缝合的圆锥角膜手术病例中,穿透性角膜移植手术能有效改善病人的角膜表面规则程度,与缝线拆除相关的角膜规则程度呈动态变化,该变化主要发生在轻、中度组,缝线拆除本身并不会导致术后角膜规则程度下降。 | 刘毅 Berthold Seitz Achim Langenbucher Nhung X.Nguyen Gottfried O.H.Naumann | 2007 | 中国实用眼科杂志2007，25，4： | 3 |
| 11 | Kontrastverst?rkte Sonografie (CEUS) zur Charakterisierung fokaler Leberl?sionen in der klinischen Routine (DEGUM-Multicenterstudie): CEUS vs. MRI – ein prospektiver Vergleich bei 269 Patienten显示文摘 | K. Seitz T. Bernatik D. Strobel W. Blank M. Friedrich-Rust H. Strunk C. Greis W. Kratzer A. Schuler | 2010 | Ultraschall in Med2010，，05： | 2 |
| 12 | A standardized injection technique and regimen ensures success and safety of N-butyl-2-cyanoacrylate injection for the treatment of gastric fundal varices (with videos)显示文摘 | Stefan Seewald Tiing Leong Ang Hiroo Imazu Mazen Naga Salem Omar Stefan Groth Uwe Seitz Yan Zhong Frank Thonke Nib Soehendra | 2008 | Gastrointestinal Endoscopy2008，，3： | 2 |
| 13 | Genetics of the quantitative Lp(a) lipoprotein trait显示文摘 | Gerd Utermann Hans Georg Kraft Hans Jürgen Menzel Thomas Hopferwieser Christoph Seitz | 1988 | Human Genetics1988，，1： | 2 |
| 14 | Role of the premotor cortexin recovery from middle cerebral artery infarction 显示文摘 | Seitz R J Hflich P Binkofski F | 1998 | Arch Neuro11998，55，： | 2 |
| 15 | The role of diaschisis in stroke recovery显示文摘 | Seitz RJ Azari NP Knorr U | 1999 | Stroke1999，30，： | 2 |
| 16 | Kontrastmittelsonografie bei B-Bild-morphologisch unklaren Leberraumforderungen – Diagnostische Treffsicherheit im klinischen Alltag (DEGUM-Multicenter – Studie)显示文摘 | D Strobel K Seitz W Blank A Schuler C Dietrich A Herbay M Friedrich-Rust G Kunze D Becker U Will W Kratzer F Albert C Pachmann K Dirks H Strunk C Greis T Bernatik | 2008 | Ultraschall in Med2008，，05： | 2 |
| 17 | Tactile exploration of shape after subcortical ischaemic infarction studied with PET 显示文摘 | Weder B Herzog H Seitz R | 1994 | Brain1994，117，： | 2 |
| 18 | Extrusion Based Additive Manufacturing of Metal Parts显示文摘 | Clemens Lieberwirth Arne Harder Hermann Seitz | 2017 | Journal of Mechanics Engineering and Automation2017，7，2： | 2 |
| 19 | Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22:linkage analysis in German breast cancer families显示文摘 | Seitz S Rohde K Bender E | 1997 | Oncogene1997，14，6： | 1 |
| 20 | Penetrating keratoplasty for atrogenic keratoconus after repeat myopic laser in situ keratomileusis:histologic findings and literature review显示文摘 | Seitz B Rozsival P Feuermannova A | 2003 | J Cataract Refract Surg2003，29，11： | 1 |
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