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| 1 | Etiology and portal vein thrombosis in Budd-Chiari syndrome显示文摘AIM: To research the etiology, portal vein thrombosis and other features of Budd-Chiari syndrome (BCS) patients prospectively. METHODS: A total of 75 patients (40 female, 35 male) who were diagnosed between January 2002 and July 2004 as having BCS were studied prospectively. Findings from on physical examination, ultrasonography, duplex ultrasonography and venography were analyzed. Hemogram and blood chemistry were studied at the time of diagnosis and on each hospital visit. Bone marrow examination and immune phenotyping were performed by a hematologist when necessary. Protein C, S, antithrombin Ⅲ, activated protein C resistance, and anticardiolipin antibodies, antinuclear antibodies, and anti ds-DNA were studied twice. The presence of ascite, esophageal varices, and portal thrombosis were evaluated at admission and on every visit. RESULTS: At least one etiological factor was determined in 54 (72%) of the patients. The etiology could not be defined in 21 (28%) patients. One etiological factor was found in 39, 2 factors in 14 and 3 factors in 1 patient. The most common cause was the web (16%), the second was Hydatid disease (11%), the third was Behcet’s disease (9%). Portal vein thrombosis was present in 11 patients and at least one etiology was identified in 9 of them (82%). CONCLUSION: Behcet’s disease and hydatid disease are more prominent etiological factors in Turkey than in other countries. Patients with web have an excellent response to treatment without signs of portal veinthrombosis while patients having thrombofilic factors more than one are prone to develop portal vein thrombosis with worse clinical outcome. | Oguz Uskudar Meral Akdogan Nurgul Sasmaz Sevinc Yilmaz Muharrem Tola Burhan Sahin | 2008 | World Journal of Gastroenterology2008，14，18： | 14 |
| 2 | Hepatic fibrosis in biliary-obstructed rats is prevented by Ginkgo biloba treatment显示文摘AIM: To assess the antioxidant and antifibrotic effects of long-term Ginkgo biloba administration on liver fibrosis induced by biliary obstruction in rats.METHODS: Liver fibrosis was induced in male Wistar albino rats by bile duct ligation and scission (BDL). Ginkgo administered for 28 d. At the end of the treatment period,all rats were killed. Serum aspartate aminotransferase (AST),alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were determined to assess liver functions and tissue damage, respectively. Tumor necrosis factor-α (TNF-α) was also assayed in serum samples. Liver tissues were taken for determination of the hepatic malondialdehyde (MDA) and glutathione (GSH) levels,myeloperoxidase (MPO) activity and collagen content.Production of reactive oxidants was monitored by chemiluminescence (CL) assay. Serum AST, ALT, LDH, and TNF-α levels were elevated in the BDL group as compared to control group and were significantly decreased by EGb treatment.RESULTS: Hepatic GSH level, depressed by BDL, was elevated back to control level in EGb-treated BDL group.Increase in tissue MDA level, MPO activity and collagen content due to BDL were also attenuated by EGb treatment.Furthermore, luminol and lucigenin CL values in BDL group increased dramatically compared to control and reduced by EGb treatment.CONCLUSION: Our results suggest that Ginkgo biloba protects the liver from oxidative damage following BDL in rats. This effect possibly involves the inhibition of neutrophil infiltration and lipid peroxidation; thus, restoration of oxidant and antioxidant status in the tissue. | Gksel pener Levent Kabasakal Meral Yüksel Nursal Gedik Ynci Alican | 2005 | World Journal of Gastroenterology2005，11，35： | 7 |
| 3 | Effect of early preoperative 5-fluorouracil on the integrity of colonic anastomoses in rats显示文摘AIM:To determine the effect of chemotherapy on wound healing by giving early preoperative 5-fluorouracil (5-FU)to rats with colonic anastomoses. METHODS:Sixty Albino-Wistar male rats(median weight,235 g)were used in this study.The rats were fed with standard laboratory food and given tap water ad libitum.The animals were divided into three groups: Group 1:Control group(chemotherapy was not administered),Group 2:Intraperitoneally(IP)administered 5-FU group(chemotherapy was administered IP to animals at a dose of 20 mg/kg daily during the 5 d preceeding surgery),Group 3:Intravenously(IV)administered 5-FU group.Chemotherapy was administered via the penil vein,using the same dosing scheme and duration as the second group.After a 3-d rest to minimize the side effects of chemotherapy,both groups underwent surgery.One centimeter of colon was resected 2 cm proximally from the peritoneal reflection,thensutured intermittently and subsequently end-to-end anastomosed.In each group,half the animals were given anaesthesia on the 3rd postoperative(PO)day and the other half on the 7th PO day,for in vivo analytic procedures.The abdominal incisions in the rats were dissected,all the new and old anastomotic segments were clearly seen and bursting pressures of each anastomotic segment,tissue hydroxyproline levels and DNA content were determined to assess the histologic tissue repair process. RESULTS:When the IV group was compared with the IP group,bursting pressures of the anastomotic segments on the 3rd and 7th PO days,were found to be significantly decreased,hydroxyproline levels at the anastomotic segment on the 7th PO day were significantly decreased(P<0.01). CONCLUSION:In this study,we conclude that early preoperative 5-FU,administered IV,negatively affects wound healing.However,IP administered 5-FU does not negatively affect wound healing. | Leyla Ozel M Sefa Ozel Ahmet Burak Toros Melih Kara Kemal Sirri Ozkan Gurkan Tellioglu Osman Krand Meral Koyuturk Ibrahim Berber | 2009 | World Journal of Gastroenterology2009，15，33： | 7 |
| 4 | Rhabdomyolysis with different etiologies in childhood显示文摘AIM To investigate different etiologies and management of the rhabdomyolysis in children.METHODS Eight pediatric rhabdomyolysis cases who applied to the Dokuz Eylul University Faculty of Medicine Department of Pediatric Nephrology with different etiologies between January 2004 and January 2012 were evaluated in terms of age, gender, admission symptoms, physical examination findings, factors provoking rhabdomyolysis, number of rhabdomyolysis attacks, laboratory results, family history and the final diagnosis received after the treatment. RESULTS Average diagnosis ages of eight cases were 129(24-192) ± 75.5 mo and five of them were girls. All of them had applied with the complaint of muscle pain, calf pain, and dark color urination. Infection(pneumonia) and excessive physical activity were the most important provocative factors and excessive licorice consumption was observed in one case. In 5 cases, acute kidney injury was determined and two cases needed hemodialysis. As a result of the further examinations; the cases had received diagnoses of rhabdomyolysis associated with mycoplasma pneumoniae, sepsis associated rhabdomyolysis, licorice-induced hypokalemic rhabdomyolysis, carnitine palmitoyltransferase Ⅱ deficiency, very long-chain acyl-CoA dehydrogenase deficiency, congenital muscular dystrophy and idiopathic paroxysmal rhabdomyolysis(Meyer-Betz syndrome).CONCLUSION It is important to distinguish the sporadic and recurrent rhabdomyolysis cases from each other. Recurrent rhabdomyolysis cases should follow up more regardful and attentive. | Demet Alaygut Meral Torun Bayram Belde Kasap Alper Soylu Mehmet Türkmen Salih Kavukcu | 2017 | World Journal of Clinical Pediatrics2017，6，4： | 5 |
| 5 | Extensive hepatic-portal and mesenteric venous gas due to sigmoid diverticulitis显示文摘Hepatic portal venous gas is most often associated with extensive bowel necrosis due to mesenteric infarction.Mortality exceeds 75% with this condition.The most common precipitating factors include ischemia,intra-abdominal abscesses and inflammatory bowel disease.In this report,we present a 75-year-old woman with extensive hepatic portal and mesenteric venous gas due to colonic diverticulitis.She had a 10-year history of type diabetes mellitus and hypertension.She was treated by sigmoid resection and Hartmann's procedure and discharged from the hospital without any complications. | Meral Sen Ayhan Akpinar Aydin Snan Mete Sisman Cenap Dener Kayihan Akin | 2009 | World Journal of Gastroenterology2009，15，7： | 4 |
| 6 | Efficient adsorption of Th(Ⅳ)from aqueous solution by modified SBA-15 mesoporous silica显示文摘A very effective adsorbent for thorium has been obtained by modification of Santa Barbara Amorphous(SBA-15) using the chelating agent thenoyltrifluoroacetone(TTA).The prepared adsorbent(SBA-15-TTA) was characterized using scanning electron microscopy(SEM),Fourier transform infrared spectroscopy(FT-IR),surface area,porosity,and zeta potential analyses.We investigated the factors affecting Th(IV) adsorption on TTA-SBA-15,such as initial p H,contact time,temperature,and initial metal concentration.The effective initial p H for adsorption was found to be 4.The binding sites on TTA-SBA-15 adsorbent were saturated using an initial Th(IV) concentration of 100 mg L-1.The Dubinin–Radushkevich isotherm suggested a strong chemical interaction between adsorbent and adsorbate.Contact time and temperature had no significant effect on the adsorption.Therefore,the studies show that TTA-SBA-15 is a promising adsorbent to treat Th(IV)-contaminated effluents. | Mutlu Gok Senol Sert Gulcin Ozevci Meral Eral | 2018 | Nuclear Science and Techniques2018，29，7： | 3 |
| 7 | 银离子在斛壳丹宁酸树脂表面的吸附和解吸(英文)显示文摘将斛壳丹宁酸与甲醛聚合来形成的凝胶作为吸附剂能有效地移去水溶液中的银离子。研究了不同银离子初始浓度、溶液温度、pH值条件下斛壳丹宁酸树脂的附和解吸行为。研究了有关经验动力学模型的适应性。伪二级动力学模型表明银离子的吸附是很快的。用FTIR和SEM对吸附和解吸银离子后的斛壳彤宁酸和斛壳丹宁酸树脂进行表征。银离子在斛壳宁酸树脂上的吸附随着银离子初始浓度的增加而增加,随着溶液温度的升高而减少。在低pH值的H2SO4、HNO3和HCl溶液中进行解吸实验。斛壳丹宁酸树脂在pH2.0~7.0溶液中对银离子表现出高的吸附容量,在银离子初始浓度100.0 mg/L、温度296 K和pH5.0的条件下达到最大的吸附量97.08 mg/g。在1 mol/L HCl+1%硫脲溶液中银离子的脱吸率达99.6%。 | Meral YURTSEVER .Ayhan SENGL | 2012 | Transactions of Nonferrous Metals Society of China2012，22，11： | 2 |
| 8 | Reirradiation for locally recur-rent nasopharyngeal carcinoma: treatment results and prognostic factors显示文摘 | Oksuz DC Meral G Uzel O | 2004 | Int J Radiat Oncol Biol Phys2004，60，2： | 1 |
| 9 | The effects of first premolar extractions on third molar angulations显示文摘 | Saysel MY Meral GD Kocadereli I | 2005 | Angle Orthod2005，75，5： | 1 |
| 10 | Cardiac thrombus in Omenn syndrome显示文摘 | Kilic SS Cil E Meral A et ol | 2005 | Pediatr Cardiol2005，26，5： | 1 |
| 11 | Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs显示文摘 | Meral I Mert H Men N | 2007 | Brain Res2007，1169，： | 1 |
| 12 | A placebo-controlled compari- son of repetitive doses of bet net hasone and dexam ethason on lung maturation and lung liver and body weights of mouse pups 显示文摘 | Ozdemir H Guvenal T Meral C | 2003 | Ped- aitr Res2003，53，1： | 1 |
| 13 | New adipocytokin- es (vaspin, apelin, visfatin, adiponectin) levels in chil- dren treated with valproic acid显示文摘 | Meral C Cekmez F Vurucu S | 2011 | Eur Cytokine Netw2011，22，2： | 1 |
| 14 | Reirradiation for locaJly recun'entnasopharyngeal carcinoma: txeatment results and prognostic factors 显示文摘 | Oksilz DC Meral G Uzel O | 2004 | Int J Radiat Oncol Biol Phys2004，60，2： | 1 |
| 15 | Relationship between serum lev- els of some acute-phase proteins and stage of disease and performance status in patients with lung cancer显示文摘 | Yildirim A Meral N Kaynar H | 2007 | Med Sci Monit2007，13，4： | 1 |
| 16 | Erythrocyte Membrane Anionic Content and Urinary Glycosaminoglycan Excretion in Type 1 Diabetes: Association with Retinopathy显示文摘 | ? zlem Yenice Haluk Kazoko&gbreve lu Eda ? zcan Meral Yü ksel G? ksenin Adigü zel Goncagü l Haklar Dilek Gogas Yavuz | 2006 | Current Eye Research2006，，11： | 1 |
| 17 | Plasma homocysteine levels in patients treats with levodopa motor and cognitive associations 显示文摘 | Ozer F Meral H Hanoglu L | 2006 | NeurolRes2006，28，8： | 1 |
| 18 | Safety of high-dose intravenous immunoglobulin in systemic autoimmune diseases显示文摘 | Fatih Tufan Sevil Kamali Burak Erer Ahmet Gul Murat Inanc Lale Ocal Meral Konice Orhan Aral | 2007 | Clinical Rheumatology2007，，11： | 1 |
| 19 | Effects of laser and acid etching and air abrasion on mineral content of dentin显示文摘 | Meral Arslan Malkoc | 2011 | Lasers in Medical Science2011，26，1： | 1 |
| 20 | The effects of first premolar extractions on third molar angulations 显示文摘 | Saysel MY Meral GD Kocadereli I | 2005 | Angle Orthod2005，75，5： | 1 |
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