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| 1 | Enteral glutamine pretreatment does not decrease plasma endotoxin level induced by ischemia-reperfusion injury in rats显示文摘AIM:To investigate whether oral glutamine pretreatment prevents impairment of intestinal mucosal integrity during ischemia-reperfusion (I/R) in rats. METHODS: The study was performed as two series with 40 rats in each. Each series of animals was divided into four groups. The first group was used as a control. Animals in the second group were only pretreated with oral glutamine, 1 g/kg for 4 d. The third group received a normal diet, and underwent intestinal I/R, while the fourth group was pretreated with oral glutamine in the same way, and underwent intestinal I/R. Intestinal mucosal permeability to 51Cr-labeled EDTA was measured in urine in the first series of animals. In the second series, histopathological changes in intestinal tissue and plasma endotoxin levels were evaluated. RESULTS: Intestinal I/R produced a significant increase in intestinal permeability, plasma endotoxin level and worsened histopathological alterations. After intestinal I/R, permeability was significantly lower in glutamine- treated rats compared to those which received a normal diet. However, no significant change was observed in plasma endotoxin levels or histopathological findings. CONCLUSION: Although glutamine pretreatment seems to be protective of intestinal integrity, upon I/R injury, such an effect was not observable in the histopathological changes or plasma endotoxin level. | Arda Demirkan Erkin Orazakunov Berna Sava■ M Ayhan Kuzu Mehmet Melli | 2008 | World Journal of Gastroenterology2008，14，3： | 2 |
| 2 | The chicken Il-I receptor:differential evolution of the cytoplasmic and extracellular domains显示文摘 | GUIDA S HEGUY A MELLI M | 1992 | Gene1992，111，： | 1 |
| 3 | Isolation of endogenous anti- coagulant N-sulfated glycosaminoglycans in human plasma from healthy subjects 显示文摘 | Ruggiero M Melli M Parma B | 2002 | Pathophysiol Haemost Thromb2002，32，： | 1 |
| 4 | A case-control analysis ofexposure to traffic and acute myocardial infarction显示文摘 | Tonne C Melly S Mittleman M | 2007 | Environ HealthPerspect2007，115，： | 1 |
| 5 | Comparison of platinum-based neoadjuvant chemotherapy and primary debulking surgery in patients with advanced ovarian cancer 显示文摘 | Sayyah- Melli M Zonoozi G K Hashemzadeh S et a1 | 2013 | J Obstet Gynaecol India2013，63，6： | 1 |
| 6 | Endotoxin level in is-chemia-reperfusion injury in rats:effect of glutamine pretreatment on endotoxin levels and gut morphology显示文摘 | Demirkan A Savas B Melli M | | 0，，01： | 1 |
| 7 | Soil carbon changes after 26 years in a Cumberland plateau hardwood forest显示文摘 | Melly J M Mays P A | 2005 | Soil Science Society of America Journal2005，69，3： | 1 |
| 8 | Corporate responsiveness and organizational learning显示文摘 | Post J E Mellis M | 1978 | California Man- agement Review1978，2，3： | 1 |
| 9 | Pharmacotherapy of allergic rhinitis: current options and future perspectives显示文摘 | Ridolo E Montagni M Melli V | 2014 | Expert opinion on pharmacotherapy2014，15，1： | 1 |
| 10 | Metolachlor andalachlor effect on membrane permeabity and lipid synthesis显示文摘 | MELLIS M | 1982 | Weeds Sci1982，30，4： | 1 |
| 11 | Influence of surface parameters and doping on the sensitivity and on the response times of Tin oxide resistive sensors显示文摘 | Butta N Melli M Pizzini S | 1990 | Sensors and Actuators1990，2，2： | 1 |
| 12 | Effects of fenofibrate on lipids,lipoproteins and apolipoproteins in 33 subjects with primary hypercholesterolaemia显示文摘 | Mellies M J Stein E A Khoury P | 1987 | Atherosclerosis1987，63，1： | 1 |
| 13 | Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations显示文摘 | Guerrini MM Sobacchi C Cassani B Abinun M Kilic SS Pangrazio A Moratto D Mazzolari E Clayton-Smith J Orchard P Coxon FP Helfrich MH Crockett JC Mellis D Vellodi A Tezcan I N otarangelo L D R ogers MJ V ezzoni P V illa A F rattini A | | 0，，： | 1 |
| 14 | A case-control analy- sis of exposure to traffic and acute myocardial infarction显示文摘 | Tonne C Melly S Mittleman M | 2007 | Environ Health Perspect2007，115，： | 1 |
| 15 | Soil carbon changes after 26 years in a Cumberland plateau hardwood forest soil 显示文摘 | Melly J M Mays P A | 2005 | Science Society of America Journal2005，69，： | 1 |
| 16 | Estimation of Quantile Treatment Effects with Stata 显示文摘 | Frfilich M Melly B | 2010 | The Stata Journal2010，10，3： | 1 |
| 17 | Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental che-motherapy neuropathy 显示文摘 | Melli G Taiana M Camozzi F | 2008 | Exp Neurol2008，214，2： | 1 |
| 18 | Pharmacotherapy of aller- gic rhinitis: current options and future perspectives 显示文摘 | Ridolo E Montagni M Melli V | 2014 | Expert Opin Pharmacother2014，15，1： | 1 |
| 19 | A burn specific health scale显示文摘 | Blades B Mellis N Muster A M | 1982 | J Trauma1982，9，2： | 1 |
| 20 | Angiotensin Ⅱ - induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle 显示文摘 | WEBER D S ROCIC P MELLIS A M | 2005 | Am J Physiol Heart Circ Physiol2005，288，1： | 1 |
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