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| 1 | Precision ERS-2 orbit deter-mination combining multiple tracking techniques显示文摘Both of the oceanographic research by using altimetry and the application of InSAR of ERS-2 satellite need the precise ephemerides of the satellite. In this note, the ERS-2 orbit is precisely determined by using SLR and PRARE observations to take advantage of the high accuracy of SLR and the widespread data coverage of PRARE. Based on the software system SODS-VCE established by us, the ERS-2 orbits in 1997 are calculated. The evaluation from tracking data fits, endpoint consistency of orbital arcs and comparison with independent orbit implies an orbit accuracy of 5-6 cm in radial component which can satisfy the requirement of being better than 10 cm in oceanographic research by altimetry, being less than 20 cm in cross-track component which can meet the requirement of InSAR. In orbit computation, the method of variance component estimation is employed to weight the SLR, PRARE range and Doppler measurements properly. The results indicate that the application of the method can improve the computation | Zhang, FP Huang, C Liao, XH Feng, CG | 2001 | Chinese Science Bulletin2001，46，20： | 7 |
| 2 | 三种药物联合清除耐多粘菌素和碳青霉烯类药物的鲍曼不动杆菌显示文摘目的 耐多粘菌素鲍曼不动杆菌的出现使临床医生对多重耐药鲍曼不动杆菌感染的治疗束手无策。研究体外模拟多粘菌素耐药菌株的出现,评价耐多粘菌素菌株感染的联合用药效果。 | 豆清娅 吴安华 Lenhard JR Thamlikitkul V Silveira FP | 2017 | 中国感染控制杂志2017，16，7： | 5 |
| 3 | γ-羟基丁酸的药理学和毒理学:血检和尿检以及急性中毒和戒断综合征的治疗显示文摘γ-羟基丁酸(γ-hydroxybutyrate,GHB)是一种强效中枢镇静剂,其违法滥用在司法鉴定案件中很常见,γ-羟基丁酸钠也可作为一种药品在一些国家合法使用,主要用于治疗发作性睡病相关的猝倒症状以及辅助酗酒者的脱毒和戒断治疗。生理状态下,包括大脑在内的多种组织都可以产生微量的GHB(0.5-1.0 mg/L),它既是γ-氨基丁酸(γ-aminobutyric acid,GABA)的前体,也是GABA代谢产物之一。研究表明,GHB是一种GABA能神经系统中的神经递质和神经调质,它能与GABA-B受体亚型结合发挥生理作用。虽然GHB被许多国家列为管制药品,但由于用于合成GHB的前体物质γ-丁内酯(γ-butyrolactone,GBL)和1,4-丁二醇(1,4-butanediol,BD)不属于管制药品,所以其滥用问题依然普遍存在。同时摄入GBL和BD之后,两者会迅速转化为GHB,20-40 min后达到血药高峰,随后GHB被迅速代谢排出体外,半衰期仅为30-50 min,尿液中仅有1%-5%的GHB以原型排出,检测时间窗相对较短(3-10 h),这就要求司法鉴定时应及时取样。目前还很难对娱乐性使用GHB的剂量做出准确评估,一般血浆浓度约100 mg/L时即可产生欣快感和脱抑制效应,达到500 mg/L时可引起呼吸和循环系统抑制而死亡,目前还没有能有效逆转GHB镇静和兴奋作用的解毒剂。针对GHB中毒患者,主要采用支持治疗、监测生命体征和保持呼吸道通畅。对于长期规律使用GHB的药物依赖患者,不可突然停药,否则会导致戒断综合征。除苯二氮艹卓类药物以外,目前还没有其他有效治疗GHB戒断症状的药物。 | 陈文浩(译) 王忠(审校) 谢雯(审校) 陆林(审校) Busardò FP Jones AW | 2018 | 中国药物依赖性杂志2018，27，1： | 3 |
| 4 | Bacterial communities inside and in the vicinity of the Chinese Great Wall Station, King George Island, Antarctica显示文摘 | Xiao X Li MG You ZY Wang FP | 2007 | 中国生物学文摘2007，21，8： | 3 |
| 5 | 抗疱疹药物的最新进展显示文摘为了寻找治愈疱疹病毒感染的药物,人们正在进行大量的研究。一些比较新的抗病毒剂如无环鸟苷(ACV)、溴乙烯去氧尿苷(BVdU)、氟阿糖碘胞苷(FIAC)、和磷酰甲酸(PFA)已被当作第2代抗病毒药。与第一代抗病毒药疱疹净、三氟胸苷、阿糖腺苷相比,第2代抗病毒药对病毒显示出特异的疗效。新近发展起来的第3代抗病毒药。 | Flowers FP 邓峰华 | 1990 | 国外医学(皮肤性病学分册)1990，16，2： | 2 |
| 6 | Experimental observation on ferrous l-threonate improvement on nutritional iron deficiency anemia显示文摘 | YU K WANG ZW KOU FP | 1998 | Chin Child Blood (in Chinese)1998，3，1： | 2 |
| 7 | Neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma: The need for patient-centered research显示文摘Pancreatic ductal adenocarcinoma is an aggressive cancer with high recurrence rates following surgical resection.While adjuvant chemotherapy improves survival,a significant proportion of patients are unable to initiate or complete all intended therapy following pancreatectomy due to postoperative complications or poor performance status.The administration of chemotherapy prior to surgical resection is an alternative strategy that ensures its early and near universal delivery as well as improves margin-negative resection rates and potentially improves long-term survival outcomes.Neoadjuvant therapy is increasingly being recommended to patients with pancreatic ductal adenocarcinoma,however,patient-centered research on its use is lacking.In this review,we highlight opportunities to focus research efforts in the domains of patient preferences,patient-reported outcomes,patient experience,and survivorship.Novel research in these areas may identify relevant barriers and facilitators to the use of neoadjuvant therapy thereby increasing its utilization,improve shareddecision making for patients and providers,and optimize the experience of those undergoing neoadjuvant therapy. | Jordan M Cloyd Allan Tsung John Hays Celia E Wills John FP Bridges | 2020 | World Journal of Gastroenterology2020，26，4： | 2 |
| 8 | 硫铝酸盐水泥化学需水量的计算显示文摘计算了贝利特 -硫铝酸盐 -铁酸盐熟料与终磨时加入的石膏完全水化时所需的化学需水量 (简称CWD) .给出了一系列反应式来预测CWD .这些工作需要大量的熟料化学分析 ,将其转化为标准矿物组成 ,还需要丰富的水化机理方面的知识 .还做了敏感性研究以找出需水量与水化作用的关系 .化学需水量对石膏含量非常敏感 ,特别在质量分数 0~ 3 0 %范围内 .以水灰比m(w) /m (c)表示 (包含石膏中的水 ) ,当石膏质量分数由 0增至3 0 %时 ,典型矿物完全水化的化学需水量大约在 0 .3 7~ 0 .62之间 .波特兰水泥混凝土在孔中常残留多余的水 ,硫铝酸盐水泥混凝土则不同 ,在浇注时有足够的流动性 ,而水化后达到一种“内干”状态 ,即不含自由孔隙水 .文中报道的一些硫铝酸盐水泥混凝土的性能改善与“内干”状态有关 . | Glasser FP 张量 | 2000 | 硅酸盐学报2000，28，4： | 2 |
| 9 | Treatment of primary limited cutaneous extramammary Paget's disease with topical imiquimod monotherapy:two case reports显示文摘 | Zampogna JC Flowers FP Roth WI | 2002 | JAAD2002，47，4： | 2 |
| 10 | Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families显示文摘 | Shai R Quismorio FP Jr Li L | | 0，，： | 2 |
| 11 | 新灭鼠剂杀它仗对小家鼠的围栏和现场试验显示文摘灭鼠剂的实验室研究,目前主攻方向是寻找能够克服杀鼠灵(Warfarin)等第一代抗凝血灭鼠剂抗药性有价值的化合物。主要成果是已经评价了鼠得克(Difenacoun)、溴敌隆(Bromadiolone)和大隆(Brodifacoum)对家栖鼠和其他害鼠的效果。围栏群养鼠摄食试验和现场试验结果证明,上述三种化合物防制抗杀鼠灵小家鼠(Mus mus- | Rowe FP Bradfield A Swinny T 董天义 | 1989 | 中国鼠类防制杂志1989，5，1： | 2 |
| 12 | Hemsleyasine, a New Norditerpenoid Alkaloid from the Roots of Aconitum Hemsleyanum Var.Circinatum显示文摘A new norditerpenoid alkaloid, hemsleyasine 1, has been isolated from the roots of Aconitum hemsleyanum var. circinatum W. T. Wang and its structure was established by spectral methods (1 H- and 13C-NMR. 1H COSY, COLOC and nOes). | Xu, QY Wang, FP Tan, TCM Che, CT | 1997 | Chinese Chemical Letters1997，8，2： | 2 |
| 13 | The gastroeolie trunk and its tributaries:CT evaluation显示文摘 | Mori H Mcgrath FP Malone DE | 1992 | Radiology1992，182，3： | 1 |
| 14 | Outcome of revision discectomies following recurrent lumbar disc herniation显示文摘 | Papadopoulos EC Girardi FP Sandhu HS | 2006 | Spine2006，31，13： | 1 |
| 15 | Primary liver resection and salvage transplantation or primary liver transplantation in patients with single, small hepatocellular carcinoma and preserved liver function: an outcome-oriented decision analysis 显示文摘 | Majno PE Sarasin FP Mentha G | 2000 | Hepatology2000，31，4： | 1 |
| 16 | Cloning and molecular analysis of the ornithine carbamoyl transferase gene of Aspergillus niger显示文摘 | BUXTON FP GWYNNE DI GARVEN S | 1987 | Gene1987，60，： | 1 |
| 17 | CT of the pulmonary nodule: A cooperative study 显示文摘 | Zerhouni EA Stitik FP Siegelman SS | 1986 | Radiology1986，160，2： | 1 |
| 18 | A new potent and selective histamine H3 receptor agonist immepip (vuf4708)显示文摘 | Koning JP Jansen FP | 1994 | J Med Chem1994，37，3： | 1 |
| 19 | Homecamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues 显示文摘 | Laurence LG Rodas FP | 1998 | J Med Chem1998，41，27： | 1 |
| 20 | The prevalence of contraindications to total disc replacement in a cohort of lumbar surgical patients显示文摘 | Huang RC Lim MR Girardi FP | 2004 | Spine (Phila Pa 1976)2004，29，22： | 1 |
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