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| 1 | Quality of life, physical performance and nutritional status in older patients hospitalized in a cardiology department显示文摘Objectives Quality of life(QoL) is a priority outcome in older adults suffering from cardiovascular diseases. Frailty and poor nutritional status may affect the QoL through mobility disorders and exhaustion. The objective of this study was to determine if physical frailty and nutritional status were associated with QoL, in older cardiology patients. Methods Cross sectional, observational study conducted in a cardiology department from a university hospital. Participants(n = 100) were aged 70 and older. Collected data included age, sex, cardiac diseases, New York Heart Association(NYHA) classification, comorbidities(Charlson Index) and disability. A Short Physical Performance Battery(SPPB), including walking speed assessment was performed;handgrip strength were measured as well as Fried’s frailty phenotype. Nutritional status was assessed using the Mini Nutritional Assessment(MNA) and Body Mass Index(BMI), inflammation by C-reactive protein(CRP). QoL was assessed using the EORTC–QLQ questionnaire. Univariate and multivariate analyses were performed to study the associations between all recorded parameters and QoL. Results In participants(mean age: 79.3 ± 6.7 years;male: 59%), Charlson index, arrhythmia, heart failure, NYHA class III-IV, MNA, disability, walking speed, SPPB score, frailty and CRP were significantly associated with QoL in univariate analysis. Multivariate analysis showed that NYHA class III-IV(P < 0.001), lower MNA score(P = 0.03), frailty(P < 0.0001), and higher CRP(P < 0.001) were independently associated with decreased QoL. Conclusions Frailty, nutritional status and inflammation were independently associated with poor QoL. Further studies are needed to assess the efficacy of nutritional and physical interventions on QoL in this population. | Matthieu Lilamand Mariannick Saintout Marie Vigan Astrid Bichon Laure Tourame Aurélie Brembilla Diet Bernard Iung Dominique Himbert Cédric Laouenan Agathe Raynaud-Simon | 2020 | Journal of Geriatric Cardiology2020，17，7： | 3 |
| 2 | A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human Hepatocytes显示文摘 | Sibylle Haid Alexandra Novodomská Juliane Gentzsch Christina Grethe Silvia Geuenich Dorothea Bankwitz Patrick Chhatwal Beate Jannack Thierry Hennebelle Francois Bailleul Oliver T. Keppler Marion Poenisch Ralf Bartenschlager Céline Hernandez Matthieu Lemas | 2012 | Gastroenterology2012，，1： | 2 |
| 3 | Automated drug dispensing system re- duces medication errors in an intensive care setting显示文摘 | Claire C Matthieu R Gaelle B | 2010 | Crit Care Med2010，38，12： | 1 |
| 4 | Epizootic haemorrhagic disease virus in Reunion Island: Evidence for the circulation of a new serotype and associated risk factors 显示文摘 | Catherine C S Matthieu R Corinne S | 2014 | Veterinary Microbiology2014，170，34： | 1 |
| 5 | Simultaneous down-regulation of caffeic/5-hydroxy ferulic acid-o-methyltransfer-ase I and cinnamoyl-coenzyme A reductase in the progeny from a cross between tobacco lines homozygous for each transgene consequences for plant development and lignin synthesis显示文摘 | Gaelle P Matthieu C Catherine L | 2001 | Plant Physiology2001，126，： | 1 |
| 6 | Multi-echelon inventory control in divergent systems with shipping frequencies显示文摘 | Matthieu C Van der Hei | 1999 | European J of Operational Research1999，116，2： | 1 |
| 7 | On the Availability of a k-out-of- N System Given Limited Spares and Repair Capacity Un- der a Condition Based Maintenance Strategy 显示文摘 | Karin S de Smidt-Destombes Matthieu C van der Heij- den Aart van Harten | 2004 | Relia- bility Engineering and System Safety2004，83，3： | 1 |
| 8 | On the availability of a k- out-of-N system given limited spares and repair eapaeity un- der a eondition based maintenance strategy 显示文摘 | Karin S Matthieu C Aart H | 2004 | Reliability engineering and System safely2004，83，3： | 1 |
| 9 | On the Interaction Between Ma- intenance, Spare Part Inventories and Repair Capacity for a k-out-of-n System with Wear-out 显示文摘 | Karin S de Smidt-Destombes Matthieu C van der Heij- den Aart van Harten | 2006 | European Journal of Operational Research2006，174，1： | 1 |
| 10 | Low velocity impact modelling in laminate composite panels with discrete interfaceelements 显示文摘 | Christophe B Bruno C Matthieu B | 2009 | International Journal of Solids and Structures2009，，46： | 1 |
| 11 | Strong decrease in lignin content without significant alteration of plant development is induced by simultaneous down-regulation of cinnamoyl CoA reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD) in tobacco plants显示文摘 | MATTHIEU C ABDELLAH B CATHERINE L | 2001 | The Plant Journal2001，28，3： | 1 |
| 12 | Change in cell wall polysaccharides of green bean pods during development显示文摘 | Trinette Stolle-Smits Jan Gerard Beekhuizen Matthieu T C K | 1999 | Plant Physiology1999，121，： | 1 |
| 13 | p53 status and efficacy of primary anthracyclines/alkylating agent based regimen according to breast cancer molecular classes显示文摘 | Bidard F C Matthieu M C Chollet P | 2008 | Ann Oncol2008，19，7： | 1 |
| 14 | Assessing breakage and cracks of parboiled rice kernels by image analysis techniques显示文摘 | Francis C Matthieu F Catherine B | 2010 | Food Control2010，21，4： | 1 |
| 15 | Evaluation of the relationship between plasma transfusion and nosocomial infec- tion after cardiac surgery in children younger than 1 year 显示文摘 | Alexis C Jean-Christophe R Matthieu H | 2015 | Pe- diatric Critical Care Med2015，16，2： | 1 |
| 16 | On the availability of a k-out-of-N system given limited spares and repair capacity under a condition based maintenance strategy显示文摘 | de Smidt-Destombes Karin S van der Heijden Matthieu C van Harten Aart | 2004 | Reliability Engineering and System Safety2004，3，3： | 1 |
| 17 | Automated drug dispen- sing system reduces medication errors in an intensive care set ting显示文摘 | Claire C Matthieu R Cvaelle B | 2010 | Crit Care Med2010，38，12： | 1 |
| 18 | Multi-echelon inventory control in divergent systems with shipping frequencies显示文摘 | Matthieu C van der Heijden | 1999 | European Journal of Operational Research1999，116，： | 1 |
| 19 | A method for the study of CO2 exchanges in vitro cultured vitis rupestris plantlets 显示文摘 | Matthieu F Daniel C Rose G | 1991 | Plant Cell Tissue and Organ Culture1991，27，： | 1 |
| 20 | New options and insights for survivable transport networks显示文摘 | WAYNE G DOUCETTE J MATTHIEU C | | 0，，03： | 1 |
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