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| 1 | Differing coping mechanisms, stress level and anorectal physiology in patients with functional constipation显示文摘AIM: To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls.METHODS: Constipation was diagnosed by Rome Ⅱ criteria.Coping ability and anxiety/depression were assessed by validated questionnaires. Transit time and balloon distension test were performed.RESULTS: 34.5% patients were classified as slow transit type of constipation. The total colonic transit time (56 h vs 10 h, P<0.0001) and rectal sensation including urge sensation (79 mL vs 63 mL, P = 0.019) and maximum tolerable volume (110 mL vs95 mL, P = 0.03) differed in patients and controls. Constipated subjects had significantly higher anxiety and depression scores and lower SF-36 scores in all categories. They also demonstrated higher scores of'monitoring' coping strategy (14+6 vs9+3, P = 0.001),which correlated with the rectal distension sensation (P = 0.005), urge sensation (P=0.002), and maximum tolerable volume (P = 0.035). The less use of blunting strategy predicted slow transit constipation in both univariate (P = 0.01) and multivariate analysis (P = 0.03).CONCLUSION: Defective or ineffective use of coping strategies may be an important etiology in functional constipation and subsequently reflected in abnormal anorectal physiology. | Annie OO Chan Cecilia Cheng Wai Mo Hui Wayne HC Hu Nina YH Wong KF Lam Wai Man Wong Kam Chuen Lai Shiu Kum Lam Benjamin CY Wong | 2005 | World Journal of Gastroenterology2005，11，34： | 92 |
| 2 | 长江口潮滩有机质来源的C、N稳定同位素示踪显示文摘依据长江河口潮滩自然环境特征和受人文活动影响的差异性,沿长江河口南岸潮滩选取了12个典型的监测站位,并分别于洪水季节(7月份)和枯水季节(2月份)在各监测站位进行了表层(0~2cm)沉积物样品的采集。对表层沉积物有机质中稳定碳、氮同位素进行分析与测试发现,7月份稳定碳同位素值普遍低于2月份的稳定碳同位素值,其变化范围分别为-29.8‰^-23.7‰和-27.3‰^-25.6‰;7月份和2月份稳定氮同位素分别为1.0‰~5.5‰和1.7‰~7.8‰。研究区域内,稳定碳、氮同位素的地区分布和季节变化特征揭示,有机质中的稳定碳、氮同位素组成不仅受陆源和海源有机质输入量之间消长变化的影响,同时一系列的生物地球化学过程、人为有机质的输入和沉积物粒度与叶绿素对碳、氮同位素组成均存在不同程度的改造作用。此外,利用稳定碳同位素质量平衡混合模型。 | 刘敏 侯立军 许世远 欧冬妮 蒋海燕 余婕 Gardner WayneS | 2004 | 地理学报2004，59，6： | 46 |
| 3 | 欧氏距离系数在农业气候相似性研究中的应用显示文摘本文根据地理纬度板为相近的中国河北省和美国密苏里州各13个有代表性的气象站点的30年(1951—1980年)气候资料,采用计算欧氏距离系数的方法,就5组指标(包括气候指标和农业气候指标)分析了两地区之间气候、农业气候、冬小麦气候和春玉米气候的异同及其相似区,并对欧氏距离系数反映农业气候相似程度的可靠性进行了探索,从而为以上两地区之间引进和驯化优良品种以及其它农业技术交流提供了农业气候依据,并对两地区之间各种作物的气候生产力、农业技术和各种农业问题(如作物生态、农业土壤、农业病虫害等)的比较性研究具有促进作用。 | 王雪娥 Wayne L.Decker | 1989 | 南京气象学院学报1989，12，2： | 31 |
| 4 | Association of 25-hydroxy-vitamin D levels with semen and hormonal parameters显示文摘维生素 D 层次包括繁殖混乱被连接了到各种各样的健康结果。这研究的目的是探索在浆液维生素 D 水平(25-hydroxy-vitamin D,或 25OHD ) 和精液和神经质的参数之间的协会。这是包括了从一般人口为精子发生的学习招募的 170 个健康的人的代表性的研究。完成的将军和繁殖健康问询表,和捐赠的血和精液取样的人。主要措施是神经质的(全部、免费的睾丸激素,性荷尔蒙绑定血球素, estradiol ,刺激滤泡的荷尔蒙和 luteinizing 荷尔蒙)并且精液参数,调整( n=147 )好久,身体团索引( BMI ),季节,白酒吸入并且吸烟,在与维生素 D 层次的范畴的关系,决定了 priori 。学习人口的吝啬的年龄是 29.0 ± 8.5 年和吝啬的 BMI 是 24.3 ± 3.2 kg m −2 。吝啬的 25OHD 是 34.1 ± 15.06 ng ml −1 。BMI 与 25OHD 显示出一个否定协会。精子集中,进步活动性,精子形态学,和全部的日益增多地能动的精子数的精子在有 ‘ 的人是更低的; 25OHD ≥ 50 ng ml −1' 什么时候与有 ‘ 的人相比; 20 ng ml −1≤25OHD<50 ng ml −1' 。全部的精子计数和全部的进步能动精子计数在有 ‘ 的人是更低的; 25OHD < 20 ng ml −1' 什么时候与有 ‘ 的人相比; 20 ng ml −1≤25OHD<50 ng ml −1' 。各种各样的神经质的参数的调整工具没在 25OHD 的不同范畴显示出统计差别。在结论,在高度和底层的浆液维生素 D 层次能否定地与精液参数被联系。 | Ahmad O Hammoud A Wayne Meikle C Matthew Peterson Joseph Stanford Mark Gibson Douglas T Carrell | 2012 | Asian Journal of Andrology2012，14，6： | 19 |
| 5 | Contributions of biofilm and suspended sludge to nitrogen transformation and nitrous oxide emission in hybrid sequencing batch system显示文摘Hybrid system combines the nature of suspended growth and attached growth has been widely applied to wastewater treatment.In this research, the contributions to N transformation and N2O emission by biofilm and suspended sludge in the hybrid sequencing-batch reactor for a simultaneous nitrification, denitrification and phosphorus removal process were investigated. For the hybrid system,nitrification occurred mostly in the suspended sludge, while the biofilm played the major role in denitrification. The interaction ofthe biofilm and the suspended sludge in the same reactor resulted in a better overall nitrogen removal performance with simultaneousnitrification and denitrification. However, N2O emission was the main end product of nitrogen removal for the hybrid system; whileit was N2 for the biofilm. The relative low N2O emissions from the pure biofilm and the pure suspended sludge corresponded to therelatively high nitrate at the end of the aeration period compared with the hybrid system. | Ingwei Wayne Lo Kwang Victor Lo Don S Mavinic Dean Shiskowski William Ramey | 2010 | Journal of Environmental Sciences2010，22，7： | 17 |
| 6 | 世界卫生组织-世界麻醉医师学会联盟(WHO-WFSA):麻醉安全国际标准显示文摘此麻醉安全国际标准由世界麻醉医师学会联盟(World Federation of Societies of Anaesthesiologists,WFSA)和世界卫生组织(World Health Organization,WHO)联合制订。WFSA是由150个国家的麻醉医师组成的非营利组织。本文所推荐的标准已获得WHO和WFSA成员支持,此标准适用于世界各地的麻醉工作者,旨在为麻醉工作者、专业组织、医院、机构管理者和政府提供指导和帮助,以维持和提高麻醉安全和质量。此标准涵盖专业内容、设施设备、用药及静脉输液、监测和麻醉实施等方面。高度推荐标准与强制标准作用等同,包括(但不仅限于):训练有素的、警惕的麻醉工作者持续在场,通过临床观察及脉搏血氧饱和度持续监测组织氧合及灌注;间断监测血压;通过听诊和二氧化碳检测确认气管内插管(如果有)的正确位置;应用WHO手术安全核查单;麻醉结束时完善交接系统。此国际标准仅为最低标准,而我们的目标是以所能达到的最高标准来实施麻醉,所以实际标准最好超过本文所介绍的标准。 | Adrian W.Gelb Wayne W.Morriss Walter Johnson Alan F.Merry. | 2018 | 中华麻醉学杂志2018，38，10： | 16 |
| 7 | Miniaturised percutaneous nephrolithotomy:Its role in the treatment of urolithiasis and our experience显示文摘Miniaturized percutaneous nephrolithotomy(PCNL)procedures have gained increased popularity in recent years.They aim to reduce percutaneous tract size in order to lower complication rates,while maintaining high stone-free rates.Recently,miniaturized PCNL techniques have further expanded,and can currently be classified into mini-PCNL,minimally invasive PCNL(MIP),Chinese mini-PCNL(MPCNL),ultra-mini-PCNL(UMP),micro-PCNL,mini-micro-PCNL,and super-mini-PCNL(SMP).However,despite its minimally-invasive nature,its potential superiority in terms of safety and efficacy when compared to conventional PCNL is still under debate.The aim of this review is to summarise different available modalities of miniaturized PCNL,details of instruments involved,and their corresponding safety and efficacy.In particular,this article highlights the role of the SMP and our experience with this novel technique in management of urolithiasis.Overall,miniaturized PCNL techniques appear to be safe and effective alternatives to conventional PCNL for both adult and pediatric patients.Well-designed,randomized studies are required to further investigate and identify specific roles of miniaturized PCNL techniques before considering them as standard rather than alternative procedures to conventional PCNL. | Guohua Zeng Wei Zhu Wayne Lam | 2018 | Asian Journal of Urology2018，5，4： | 16 |
| 8 | Premature ejaculation: current and future treatments显示文摘早泄(PE ) 被认出是最普通的男性混乱。因为有食物药品管理局(食物及药品管理局) 同意的既不一个普遍接受的定义也不药, PE 为对待这个条件的专业人员提供困难。尽管有这些缺点,医生们继续根据主要指南与 PE 诊断他们的病人并且与行为的治疗或离开标签药对待他们。这评论为 PE 集中于当前、新兴的治疗选择和药。每种治疗选择的优点和限制根据当前的出版考察同伴的文学被讨论。 | Levent Gurkan Matthew Oommen Wayne J. G. Hellstrom | 2008 | Asian Journal of Andrology2008，10，1： | 15 |
| 9 | 应用聚合酶链式反应检测禽痘病毒田间分离株及疫苗株中网状内皮组织增殖病毒LTR片断,env及re1基因显示文摘本文利用聚合酶链式反应对来自澳大利亚昆士兰州、维多利亚州和新南维尔士州的4株禽痘病毒田间分离株及二疫苗株中网状内皮组织增殖病毒的LTR片断、env及rel基因因进行了检测。所有4株痘病毒分离株均为LTR片断、env阳性,曾被PCR证实为LTR阳性的一疫苗株在本实验中也为LTR、env阳性,另一疫苗株为LTR、env阴性,所有上述禽痘病毒株均为rel阴性。 | 段宏安 IBRAHIM DIALLO PETER SPRADBROW WAYNE ROBINSON | 1999 | 中国兽医杂志1999，25，8： | 14 |
| 10 | Eigenvalue approximation from below using non-conforming finite elements显示文摘This is a survey article about using non-conforming finite elements in solving eigenvalue problems of elliptic operators,with emphasis on obtaining lower bounds. In addition,this article also contains some new materials for eigenvalue approximations of the Laplace operator,which include:1) the proof of the fact that the non-conforming Crouzeix-Raviart element approximates eigenvalues associated with smooth eigenfunctions from below;2) the proof of the fact that the non-conforming EQ rot1 element approximates eigenvalues from below on polygonal domains that can be decomposed into rectangular elements;3) the explanation of the phenomena that numerical eigenvalues λ 1,h and λ 3,h of the non-conforming Q rot1 element approximate the true eigenvalues from below for the L-shaped domain. Finally,we list several unsolved problems. | YANG YiDu 1 ,ZHANG ZhiMin 2 & LIN FuBiao 11 School of Mathematics and Computer Science,Guizhou Normal University,Guiyang 550001,China 2 Department of Mathematics,Wayne State University,Detroit,MI 48202,USA | 2010 | Science China Mathematics2010，53，1： | 12 |
| 11 | Current Controversies and the State of the Art in Endovascular Treatment of Vascular Malformations显示文摘Vascular anomalies constitute some of the most difficult diagnostic and therapeutic enigmas that can be encountered in the practice of medicine. The clinical presentations are extremely protean and can range from an asymptomatic birthmark to fulminant。 | Wayne Yakes Alexis Yakes Fiona Rohlffs Krasnodar Ivancev | 2018 | Journal of Interventional Medicine2018，1，2： | 12 |
| 12 | Mutation of the Arabidopsis Calmodulin-Like Protein CML37 Deregulates the Jasmonate Pathway and Enhances Susceptibility to Herbivory显示文摘在整个他们的生活,植物被各种各样的不能生活、关於生命的压力因素质问。在那些之中是从食草的昆虫的攻击。位于草食动物和随后的信号 transduction 的察觉下面的分子的机制很好没被理解。作为第二个送信人,在细胞内部的 Ca 2+ 层次的流动在调停起一个关键作用压力反应小径。Ca 2+ 信号被象象 calmodulin 一样蛋白质(电流型逻辑) 那样的 Ca 2+ 传感器蛋白质译码。这里,我们证明 recombinant CML37 在 vitro 象一个 Ca 2+ 传感器一样表现并且在 Arabidopsis, AtCML37 被机械伤害以及由群袭与通晓各方面知识经验丰富的人的幼虫导致鳞翅类的草食动物 Spodoptera littoralis。CML37 的功能的损失导致了建议 CML37 是一个积极防卫管理者的幼虫的更好的喂表演。尽管在 jasmonates 的累积的重要减小被观察,在象 glucosinolates 或 flavonoids 那样的第二等的代谢物的导致 herbivory 的变化都没在 cml37 植物被检测,由于 JAR1 mRNA 和细胞的酶活动的减少的表示。因而, jasmonate 应答的基因的表示也被减少。总结,我们的结果建议 Ca 2+ 传感器蛋白质, CML37,在在 herbivory,连接 Ca 2+ 并且 jasmonate 发信号期间发信号的 Ca 2+ 作为一个积极管理者工作。 | Sandra S. Scholz Jyothilakshmi Vadassery Monika Heyer Michael Reichelt Kyle W. Bender Wayne A. Snedden Wilhelm Boland Axel Mithofer | 2014 | Molecular Plant2014，7，12： | 11 |
| 13 | 超重与男性生殖能力研究进展:睡眠呼吸暂停,一个新领域显示文摘肥胖会对男性生殖产生负面影响,主要是因为肥胖与低睾酮水平和促性腺激素改变有关。男性肥胖已经被发现与男性生育力下降有关,但由于影响的性质和程度不同,肥胖与精子参数相关性的数据存在争议。一些新研究领域的出现,如遗传多态性和睡眠呼吸暂停,将有助于解释研究结果的差异性。已经发现睡眠紊乱与男性睾酮生成的变化和性腺功能低下有关,也可能与勃起功能障碍有关。睡眠紊乱与不育和精子参数的关系还有待研究。忠有性腺功能低下和不育的男性应该进行睡眠呼吸暂停症的筛查。对肥胖和睡眠呼吸暂停的治疗可以改善睾酮水平和勃起功能。 | Ahmad O Hammoud Douglas T Carrell Mark Gibson C Matthew Peterson A Wayne Meikle | 2012 | Asian Journal of Andrology2012，14，1： | 11 |
| 14 | Microalgae:A potential alternative to health supplementation for humans显示文摘Microalgae has been consumed in human diet for thousands of years.It is an under-exploited crop for production of dietary foods.Microalgae cultivation does not compete with land and resources required for traditional crops and has a superior yield compared to terrestrial crops.Its high protein content has exhibited a huge potential to meet the dietary requirements of growing population.Apart from being a source of protein,presence of various bio-active components in microalgae provide an added health benefit.This review describes various microalgal sources of proteins and other bio-active components.One of the heavily studied group of bio-active components are pigments due to their anticarcenogenic,antioxidative and antihypertensive properties.Compared to various plant and floral species,microalgae contain higher amounts of pigments.Microalgal derived proteins have complete Essential Amino Acids(EAA)profiles and their protein content is higher than conventional sources such as meat,poultry and dairy products.However,microalgal based functional foods have not flooded the market.The lack of awareness coupled with scarce incentives for producers result in under-exploitation of microalgal potential.Application of microalgal derived components as dietary and nutraceutical supplements is discussed comprehensively. | Apurav Krishna Koyande Kit Wayne Chew Krishnamoorthy Rambabu Yang Tao Dinh-Toi Chu Pau-Loke Show | 2019 | Food Science and Human Wellness2019，8，1： | 10 |
| 15 | Polynomials,Higher Order Sobolev Extension Theorems and Interpolation Inequalities on Weighted Folland-Stein Spaces on Stratified Groups | Guozhen Lu Department of Mathematics,Wayne State University,Detroit,MI 48202,USA | 2000 | Acta Mathematica Sinica,English Series2000，16，3： | 9 |
| 16 | Risk of New-Onset Atrial Fibrillation in Elderly Patients with the Overlap Syndrome: A Retrospective Cohort Study显示文摘Background Co-existence of obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) is referred to as overlap syndrome. Overlap patients have greater degree of hypoxia and pulmonary hypertension than patients with OSA or COPD alone. Studies showed that elderly patients with OSA alone do not have increased risk of atrial fibrillation (AF) but it is not known if overlap patients have higher risk of AF. Objective To determine whether elderly patients with overlap syndrome have an increased risk of AF. Methods In this single center, community-based retrospective cohort analysis, data were collected on 2,873 patients > 65 years of age without AF, presenting in the year 2006. Patients were divided into OSA group (n = 60), COPD group (n = 416), overlap syndrome group (n = 28) and group with no OSA or COPD(n = 2369). The primary endpoint was incidence of new-onset AF over the following two years. Logistic regression was performed to adjust for heart failure (HF), coronary artery disease, hypertension (HTN), cerebrovascular disease, cardiac valve disorders, diabetes mellitus, hyperlipidemia, chronic kidney disease (CKD) and obesity. Results The incidence of AF was 10% in COPD group, 6% in OSA group and 21% in overlap syndrome group (P < 0.05). After adjusting for age, sex, HF, CKD, and HTN, patientswith overlap syndrome demonstrated a significant association with new-onset AF (OR = 3.66, P = 0.007). HF, CKD and HTNwere also significantly associated with new-onset AF (P < 0.05). Conclusion Among elderly patients, the presence of overlap syndrome is associatedwith a marked increase in risk of new-onset AF as compared to the presence of OSA or COPDalone. | Harsha V. Ganga Sanjeev U. Nair Venkata K. Puppala Wayne L. Miller | 2013 | Journal of Geriatric Cardiology2013，10，2： | 9 |
| 17 | Current updates on laboratory techniques for the diagnosis of male reproductive failure显示文摘导致不孕的男繁殖失败的发生,是否由于推迟的做家长,环境问题,基因因素,药,等等,在全世界正在增加。男 subfertility 的诊断和预后成为了挑战。当基本精液评价被执行许多年了时,很多研究询问传统的精液特征的价值。这是部分由于不适当的方法和标准化,为优秀保证的技术要求的有限知识,和一个精液评价能提供临床的信息的不完全的理解。当前执行精液和内分泌的评价表演伟人可变性的实验室。世界健康组织() 精液的评估的手册是在许多年在这个领域的进一步的开发帮助了的 andrology 和生育力评估的核心。这些包括精液,对精子计数的评价,活动性,活力,形态学,和精子和精液样品的功能的方面的物理外观。这些测试也由于氧化应力包括男内分泌的侧面,精液的生物化学的评估,在浆液的 antisperm 抗体的察觉,电脑辅助的精子分析(房屋) 的使用,精子 DNA 正直,和它的损坏。帮助繁殖技术(例如, IVF, ICSI ) 显示出大成功,但是是太昂贵的。与更新的技术在这块地里推进开发,广泛的火车 / 说明能改进精确性和还原剂可变性,因此维持如此的评估的质量和标准。有迫切需要标准化了训练中心并且为繁殖成功在 mens 健康的这个区域增加了了解。 | Suresh C Sikka Wayne JG Hellstrom | 2016 | Asian Journal of Andrology2016，18，3： | 9 |
| 18 | Adiponectin resistance and vascular dysfunction in the hyperlipidemic state显示文摘胰岛素在脉管的氮的氧化物生产的刺激起一个重要作用,与两个短术语(vasomotility 和 anti-thrombotic 效果) 并且长期(光滑的肌肉房间生长和迁居抑制) 受益。对胰岛素的损害 vasodilatory 反应,脉管的胰岛素抵抗(红外) 的特点,为循环 pathophysiology 有重要含意。在 adipokines 和红外之间的一个协会在糖尿病患者和 nondiabetic 状态被观察了。Adiponectin (APN ) 是知道刺激骨胳的肌肉的敏化胰岛素的 adipokine 丰满的酸(FA ) 氧化和还原剂类脂化合物累积。在在脉管的功能规定的 APN 和胰岛素之间的潜在的串音的最近的示范特别地有趣。观察在以后的类脂化合物累积长期高脂肪(HF ) 节食并且可以处于肥胖的状态把脉管的反应归结为 APN,一个病理学的状态作为 APN 抵抗称为。这评论在 endothelial 功能的维护强调胰岛素敏感和 APN 活动的重要性。它在 hyperlipidemic 探索在脉管的红外和 APN 抵抗之间的关系病理学的状况,新陈代谢的症候群的代表。脉管的胰岛素和 APN 抵抗的调查为在新陈代谢的症候群影响的个人的治疗学的指向提供脉管的 pathophysiology,而且一个机会的不仅更好的理解。 | Rong LI Wayne Bond LAU Xin Liang MA | 2010 | Acta Pharmacologica Sinica2010，31，10： | 9 |
| 19 | 用于金融文本挖掘的多任务学习预训练金融语言模型显示文摘近年来,机器学习,尤其是深度神经网络方法促进了金融文本挖掘研究的发展,在金融科技(Fintech)领域起着越来越重要的作用.如何从金融大数据中提取有价值的信息已经成为学术界和工业界一个非常有挑战的研究.由于深度神经网络需要大量标注数据,但是金融领域缺乏训练数据,因此,将深度学习应用于金融大数据挖掘并没有取得很好效果.为了更好地解决该问题,利用自监督学习和多任务学习等深度学习领域最新的思想和技术,提出了基于BERT模型架构的开源金融预训练语言模型F-BERT.F-BERT是一种针对特定领域(金融文本数据)的预训练语言模型,它通过在大型金融语料库上进行无监督训练得到.基于BERT架构,F-BERT可以有效地自动将知识从金融大数据中提取出并记忆在模型中,而无需进行特定于金融任务的模型结构修改,从而可以直接将其应用于下游各种金融领域任务,包括股票涨跌预测、金融情绪分类、金融智能客服等.在金融关系提取、金融情绪分类、金融智能问答任务上的大量实验表明了F-BERT模型的有效性和鲁棒性.同时,F-BERT在这3个有代表性的金融文本挖掘任务上均取得了很高的模型准确率,进一步验证了模型的性能. | 刘壮 刘畅 Wayne Lin 赵军 | 2021 | 计算机研究与发展2021，58，8： | 8 |
| 20 | Diagnosis and management of venous malformations: An overview显示文摘Venous malformations pose some of the most difficult challenges in the practice of medicine today. Clinical manifestations of these lesions are extremely protean. Because of the rarity of these lesions, most clinicians have limited experience in their diagnosis and management, which augments the enormity of the problem and can lead to misdiagnoses, inadequate treatment, high complication rates, and poor patient outcomes. Vascular malformations are best treated in medical centers where patients with these maladies are seen regularly and the team approach is used. The occasional embolizer will never gain enough experience to treat these problematic lesions adequately. More importantly, when complications do occur, the morbidity of that complication is worsened because of this lack of experience and the absence of an experienced team of physicians. All too frequently, the patient ultimately pays for a physician's initial enthusiasm, inexperience, folly, and lack of necessary clinician backup. A cavalier approach to the management of venous malformations will always lead to significant complications and dismal patient outcomes. These patients should be referred to centers that regularly treat vascular malformations, appropriately manage complications in a timely manner, and routinely deal with the dilemmas they present. Only in this fashion can significant experience be gained, improved judgment in managing these lesions develop, and definitive appropriate statements in the treatment of vascular anomalies evolve. | Wayne F. Yakes | 2008 | 中国口腔颌面外科杂志2008，6，1： | 7 |
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