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| 1 | Tumor-stroma ratio as prognostic factor for survival in rectal adenocarcinoma: A retrospective cohort study显示文摘AIM To evaluate the prognostic value of the tumor-stroma ratio(TSR) in rectal cancer.METHODS TSR was determined on hematoxylin and eosin stained histological sections of 154 patients treated for rectal adenocarcinoma without prior neoadjuvant treatment in the period 1996-2006 by two observers to assessreproducibility. Patients were categorized into three categories: TSR-high [carcinoma percentage(CP) ≥ 70%], TSR-intermediate(CP 40%, 50% and 60%) and TSR-low(CP ≤ 30%). The relation between categorized TSR and survival was analyzed using Cox proportional hazards model.RESULTS Thirty-six(23.4%) patients were scored as TSR-low, 70(45.4%) as TSR-intermediate and 48(31.2%) as TSRhigh. TSR had a good interobserver agreement(κ = 0.724, concordance 82.5%). Overall survival(OS) and disease free survival(DFS) were significantly better for patients with a high TSR(P = 0.01 and P = 0.02, respectively). A similar association existed for disease specific survival(P = 0.06). In multivariate analysis, patients without lymph node metastasis and an intermediate TSR had a higher risk of dying from rectal cancer(HR = 5.27, 95%CI: 1.54-18.10), compared to lymph node metastasis negative patients with a high TSR. This group also had a worse DFS(HR = 6.41, 95%CI: 1.84-22.28). An identical association was seen for OS. These relations were not seen in lymph node metastasis positive patients. CONCLUSION The TSR has potential as a prognostic factor for survival in surgically treated rectal cancer patients, especially in lymph node negative cases. | René Scheer Alexi Baidoshvili Shorena Zoidze Marloes AG Elferink Annefleur EM Berkel Joost M Klaase Paul J van Diest | 2017 | World Journal of Gastrointestinal Oncology2017，9，12： | 3 |
| 2 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functionals 显示文摘 | Marlo M Milman V | 2000 | Phys Rev B(S0163-1829)2000，62，4： | 1 |
| 3 | Density functional study of bulk and surface properties of titanium nitride using different exchange correlation function 显示文摘 | MARLO M MILMAN V | 2000 | Phys Rev B2000，62，4： | 1 |
| 4 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functionals显示文摘 | MARLO M MILMAN V | 2000 | Physical Review B2000，62，4： | 1 |
| 5 | Density-functional study of bulk and surface properties of titanium nitride using different exchange?correlation functionals显示文摘 | MARLO M MILMAN V | 2000 | Physical Review B2000，62，4： | 1 |
| 6 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functionals显示文摘 | MARLO M MILMAAN V | 2000 | Phys Rev B2000，62，： | 1 |
| 7 | 显示文摘 | Marlo M | 2000 | Phys Rev B2000，62，4： | 1 |
| 8 | 显示文摘 | Marlo M | 2000 | Phys Rev B2000，62，4： | 1 |
| 9 | Phys Rev B显示文摘 | Marlo M Milman V | 2000 | 62:28992000，62，： | 1 |
| 10 | Density-functional study of bulk and surface properties of titanium nitride using different ex- change-correlation functionals显示文摘 | Marlo M Milman V | 2000 | Physical Review B2000，62，4： | 1 |
| 11 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functionals显示文摘 | MARLO M MILMAN V | 2000 | Physical Review B2000，62，4： | 1 |
| 12 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functionals显示文摘 | Marlo M Milman V | 2000 | Phys Rev B2000，62，： | 1 |
| 13 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functionals显示文摘 | Marlo M Milman V | 2000 | Phys Rev B2000，62，4： | 1 |
| 14 | Evaluation of the rapid diagnostic test CareStart pLDH Malaria C Pf-pLDH/pan-pLDH) for the diagnosis of malaria in a reference setting显示文摘 | Marloes H Philippe G Jessica M | 2012 | Malar J2012，，11： | 1 |
| 15 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functionals显示文摘 | Marlo M Milman V | | 0，，： | 1 |
| 16 | Density-Functional Study of Bulk and Surface Properties of Titanium Nitride Using Different Exchange-Correlation Functionals显示文摘 | Marlo M Milman V | 2000 | Phys Rev B2000，62，： | 1 |
| 17 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functional 显示文摘 | Marlo M Milman V | 2000 | Physical Review B2000，62，4： | 1 |
| 18 | Supplemental Calcium Attenuates the Colitis-Related Increase in Diarrhea, Intestinal Permeability, and Extracellular Matrix Breakdown in HLA-B27 Transgenic Rats1-3显示文摘 | Schepens Marloes A A Schonewille Arjan J Vink Carolien van Schothorst Evert M Kramer Evelien Hendriks Thijs Brummer Robert-Jan Keijer Jaap van der Meer Roelof Bovee-Oudenhoven Ingeborg M J | 2009 | The Journal of Nutrition2009，，8： | 1 |
| 19 | Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: preliminary results of a randomized trial显示文摘 | Philip G Janicak Sheila M Dowd Brian Martis Danesh Alam Dennis Beedle Jack Krasuski Mary Jane Strong Rajiv Sharma Cherise Rosen Marlos Viana | 2002 | Biological Psychiatry2002，，8： | 1 |
| 20 | Density-functional study of bulk and surface properties of titanium nitride using different exchange-correlation functions显示文摘 | Milman V | 1990 | Phys Rev B1990，41，： | 1 |
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