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2145篇 您的检索式:作者名="MAHONEY"
    题名 作者 年代 出处 被引量
1峨眉山大火成岩省西部苦橄岩及其共生玄武岩的地球化学:地幔柱头部熔融的证据显示文摘丽江地区的苦橄岩位于峨眉山大火成岩省的西部,其与辉斑玄武岩、无斑玄武岩和玄武质火山碎屑岩共生。苦橄岩中的斑晶主要为富镁橄榄石,其F0含量最高达91.6%,CaO含量最高达0.42%,其内含有少量玻璃包裹体,指示了橄榄石是在熔体中结晶形成的。苦橄岩中的铬尖晶石具有高的Cr#值(73-75)。计算的初始岩浆的MgO含量大约为22wt%,初始熔融的温度为1630-1680℃。研究结果表明,玄武质岩石是苦橄质岩浆通过橄榄石和单斜辉石分离结晶形成的。苦橄岩和玄武岩的Nd-Sr-Pb同位素比值差别不大,只落在一个很小的范围内(如εNd(t)=-1.3 to+4.0)。高的εNd(t)值以及抗蚀变不相容元素的原始地幔标准化图解与洋岛玄武岩相似,并且其重稀土元素特征指示了源区有石榴子石的残余,而且是低部分熔融的产物。同位素比值与抗蚀变不相容元素比值(如Nb/La)的相关性表明,岩浆形成过程中有少量的大陆地壳物质或者相对低εNd(t)组分的大陆岩石圈地幔的混染。因此,总体上,苦橄岩的地球化学特征的研究结果支持了峨眉山大火成岩省是地幔柱头部熔融的成因模型。张招崇 John J Mahoney 王福生 赵莉 艾羽 杨铁铮 2006岩石学报2006,22,6:181
2肿瘤部位或决定结肠癌DNA错配修复功能缺陷的预后影响显示文摘目前对于接受氟尿嘧啶、亚叶酸钙及奥沙利铂(FOLFOX)辅助化疗方案治疗的结肠癌患者,DNA错配修复功能缺陷(dMMR)与预后间的联系尚不明了。美国梅奥诊所的Frank A.Sinicrope博士等人进行了一项临床试验,研究人员在2,580份肿瘤患者的蛋白芯片中,检测到314份(12%)肿瘤患者的蛋白芯片存在 dMMR,其中分别有49.3%及10.6%存在BRAFV600E或KRAS突变。尽管从整体而言,MMR状态并非预后预测因素,但研究同时发现,MMR与原发肿瘤部位及淋巴结分期( N1 v N2)间存在显著的相互作用。对突变情况及协变量校正后,研究人员发现,与准确进行MMR邻近肿瘤相对的dMMR可获得良好的DFS结局,但远端肿瘤的dMMR与良好的DFS结局无关。 N2肿瘤患者不能通过dMMR取得生存获益。BRAFV600 E突变或KRAS突变均为较差DFS的独立相关因素。根据肿瘤部位相互作用观察到的MMR得到了III期结肠癌患者独立队列的验证。Sinicrope FA Mahoney MR Smyrk TC 2013中华结直肠疾病电子杂志2013,2,4:27
3Mantle plume activity and melting conditions: Evidence from olivines in picritic-komatiitic rocks from the Emeishan Large Igneous Province, southwestern China显示文摘Zhaochong Zhang Jingwen Mao Fusheng Wang Yanli Hao John J. Mahoney 2005Episodes2005,28,3:10
4TKA术中股骨假体悬突的危险因素与临床后果显示文摘背景:近年来,全膝关节置换(total knee arthroplasty,TKA)术中的股骨假体悬突现象日益引起骨科医生的重视。本文目的为研究男性与女性患者TKA术后股骨假体悬突的发生率、确定预测悬突发生的危险因素以及假体悬突是否与术后疼痛或膝关节活动度的降低有关。方法:对437例使用同一假体系统的TKA术中的股骨假体悬突进行测量。假体牢固固定后,分别在10个分区的中点以mm刻度测量其超出截骨面边缘的悬突程度。寻找假体悬突的预测因素,并研究假体悬突对术后疼痛及膝关节屈曲度的影响。结果:男性患者176膝中的40%(71膝)、女性患者261膝中的68%(177膝)至少在1个分区内发生≥3mm悬突,且常见于外侧2区(前远侧区)和3区(远侧区)。多因素分析模型中,女性、身材矮小以及使用大号股骨假体是发生明显悬突的强预测因素。1个或1个以上分区存在≥3mm股骨假体悬突几乎可使术后2年发生明显膝关节疼痛的风险加倍[比数比1.9,95%可信区间为(1.1,3.3)]。结论:本组病例中股骨假体悬突的发生率高,女性患者更常见且更严重;不论男性患者还是女性患者,使用的股骨假体越大,假体悬突的发生率和严重程度越高。≥3mm股骨假体悬突可使TKA术后2年有临床意义的疼痛发生率加倍。OrmondeM. Mahoney Tracy Kinsey 张宇(译) 刘军(译) 2010中华骨科杂志2010,30,12:9
5Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas显示文摘David A. Ahlquist Hongzhi Zou Michael Domanico Douglas W. Mahoney Tracy C. Yab William R. Taylor Malinda L. Butz Stephen N. Thibodeau Linda Rabeneck Lawrence F. Paszat Kenneth W. Kinzler Bert Vogelstein Niels Chr. Bjerregaard S?ren Laurberg Henrik Toft S? 2012Gastroenterology2012,,2:7
6The Stool DNA Test Is More Accurate Than the Plasma Septin 9 Test in Detecting Colorectal Neoplasia显示文摘David A. Ahlquist William R. Taylor Douglas W. Mahoney Hongzhi Zou Michael Domanico Stephen N. Thibodeau Lisa A. Boardman Barry M. Berger Graham P. Lidgard 2012Clinical Gastroenterology and Hepatology2012,,3:4
7历史分析与比较政治显示文摘本文讨论了比较政治学中历史研究的主要分析方法。第一类是因果分析法,包括横截面分析法和样本内分析法。第二类是时序分析法,包括对路径依赖和发展顺序的分析。本文认为,历史分析与众不同的分析方法使它成为比较政治研究中有力的分析工具。James Mahoney Celso M. Villegas 2008浙江社会科学2008,,3:4
8Path dependence in historical sociology显示文摘James Mahoney 2000Theory and Society2000,,4:3
9Next generation per-and poly-fluoroalkyl substances:Status and trends,aquatic toxicity,and risk assessment显示文摘Widespread application of poly-and per-fluoroalkyl substances(PFAS)has resulted in some substances being ubiquitous in environmental matrices.That and their resistance to degradation have allowed them to accumulate in wildlife and humans with potential for toxic effects.While specific substances of concern have been phased-out or banned,other PFAS that are emerging as alternative substances are still produced and are being released into the environment.This review focuses on describing three emerging,replacement PFAS:perfluoroethylcyclohexane sulphonate(PFECHS),6:2 chlorinated polyfluoroalkyl ether sulfonate(6:2 Cl-PFAES),and hexafluoropropylene oxide dimer acid(HFPO-DA).By summarizing their physicochemical properties,environmental fate and transport,and toxic potencies in comparison to other PFAS compounds,this review offers insight into the viabilities of these chemicals as replacement substances.Using the chemical scoring and ranking assessment model,the relative hazards,uncertainties,and data gaps for each chemical were quantified and related to perfluorooctane sulfonic acid(PFOS)and perfluorooctanoic acid(PFOA)based on their chemical and uncertainty scores.The substances were ranked PFOS>6:2 Cl-PFAES>PFOA>HFPO-DA>PFECHS according to their potential toxicity and PFECHS>HFPO-DA>6:2 Cl-PFAES>PFOS>PFOA according to their need for future research.Since future uses of PFAS remain uncertain in the face of governmental regulations and production bans,replacement PFAS will continue to emerge on the world market and in the environment,raising concerns about their general lack of information on mechanisms and toxic potencies.Hannah Mahoney Yuwei Xie Markus Brinkmann John P.Giesy 2022Eco-Environment & Health2022,1,2:2
10Microstructural investigation of friction stir welded 7050-T651 aluminium显示文摘J.-Q Su T.W Nelson R Mishra M Mahoney 2002Acta Materialia2002,,3:2
11Microstructural investigation of friction stir welded 7050-T651 aluminium显示文摘J.-Q Su T.W Nelson R Mishra M Mahoney 2002Acta Materialia2002,,3:2
12Molecular Markers Identify Subtypes of Stage III Colon Cancer Associated with Patient Outcomes显示文摘Frank A. Sinicrope Qian Shi Thomas C. Smyrk Stephen N. Thibodeau Rodrigo Dienstmann Justin Guinney Brian M. Bot Sabine Tejpar Mauro Delorenzi Richard M. Goldberg Michelle Mahoney Daniel J. Sargent Steven R. Alberts 2014Gastroenterology2014,,:2
13An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma显示文摘George P. Kim Michelle R. Mahoney Daniel Szydlo Tony S. K. Mok Robert Marshke Kyle Holen Joel Picus Michael Boyer Henry C. Pitot Joseph Rubin Philip A. Philip Anna Nowak John J. Wright Charles Erlichman 2012Investigational New Drugs2012,,1:2
14The resource-based view within the conversation of strategic management显示文摘MAHONEY J T PANDIAN R 1992Strategic Management Journal1992,13,5:1
15High strain rate superplastieity in a friction stir processed 7075Al alloy 显示文摘MISHRA R S MAHONEY M W MCFADDEN S X 2000Scripta Materialia2000,42,:1
16Modularity Flexibility, and Knowledge Management in Product and Organization Design 显示文摘SANCHEZ R MAHONEY J 1996Strategic Management Journal1996,17,:1
17The Members of the Plakin Family of Proteins Recognized by Paraneoplastic Pemphigus Antibodies Include Periplakin显示文摘My G Mahoney Sirpa Aho Jouni Uitto 1998J Invest Dermatol1998,111,:1
18'Functional evaluation: The Barthel In- dex'显示文摘Mahoney FI Barthel D 1965Maryland State Medical Journal1965,14,:1
19Friction stir processing: A new grain refinement technique to achieve high strain rate superplasticity in commercial alloys 显示文摘MISHRA R S MAHONEY M W 2001Materials Science Forum2001,507,:1
20Intra-osseous ac- cess (EZ-IO) for resuscitation: UK military combat experience 显示文摘Cooper BR Mahoney PF Hodgetts TJ 2007J R Army Med Corps2007,153,4:1
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