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| 1 | QTL IciMapping:Integrated software for genetic linkage map construction and quantitative trait locus mapping in biparental populations显示文摘QTL Ici Mapping is freely available public software capable of building high-density linkage maps and mapping quantitative trait loci(QTL) in biparental populations. Eight functionalities are integrated in this software package:(1) BIN: binning of redundant markers;(2) MAP: construction of linkage maps in biparental populations;(3) CMP: consensus map construction from multiple linkage maps sharing common markers;(4) SDL: mapping of segregation distortion loci;(5) BIP: mapping of additive, dominant, and digenic epistasis genes;(6) MET: QTL-by-environment interaction analysis;(7) CSL: mapping of additive and digenic epistasis genes with chromosome segment substitution lines; and(8) NAM: QTL mapping in NAM populations. Input files can be arranged in plain text, MS Excel 2003, or MS Excel 2007 formats. Output files have the same prefix name as the input but with different extensions. As examples, there are two output files in BIN, one for summarizing the identified bin groups and deleted markers in each bin, and the other for using the MAP functionality. Eight output files are generated by MAP, including summary of the completed linkage maps, Mendelian ratio test of individual markers, estimates of recombination frequencies, LOD scores, and genetic distances, and the input files for using the BIP, SDL,and MET functionalities. More than 30 output files are generated by BIP, including results at all scanning positions, identified QTL, permutation tests, and detection powers for up to six mapping methods. Three supplementary tools have also been developed to display completed genetic linkage maps, to estimate recombination frequency between two loci,and to perform analysis of variance for multi-environmental trials. | Lei Meng Huihui Li Luyan Zhang Jiankang Wang | 2015 | The Crop Journal2015，3，3： | 174 |
| 2 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 3 | Mogroside V inhibits LPS-induced COX-2 expression/ROS production and overexpression of HO-1 by blocking phosphorylation of AKT1 in RAW264.7 cells显示文摘Momordica grosvenori is a valuable edible plant with medicinal purposes, and it is widely used in medicated diets and traditional Chinese medicine in Asia. Mogroside V (MV), the main bioactive component from M. grosvenori, is comm only used as a natural sweetener. M. grosvenori extracts have been reported to exert potent anti-inflammatory property, however the underlying molecular mechanism still remains unknown. In the present study, the biological effect of MV in inflammation was investigated in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. The ELISA and western blot analysis results showed that MV significantly inhibited LPS-induced prostaglandin E2 (PGE2) production and cyclooxygenase-2 (COX-2) expression. MV markedly decreased the phosphorylation of IxB-a, increased IkB-oc, and reduced nuclear p-65 and C/EBP6. Furthermore, MV attenuated LPS-induced phosphorylation of MAPKs and AKT1, and only the phosphorylation status of AKT1 was found to be consistent with the expression trend of COX-2. Moreover, MV reduced ROS level and restored overexpressed HO-1 and AP-1 to basal level, which can be markedly reversed by AKT1 inhibitor LY294002. These results revealed that AKT1 plays a key role in LPS-induced COX-2 expression, and acts as a mediator to keep the redox balance in LPS-stimulated RAW264.7 cells. MV exerts anti-inflammatory property by blocking AKT1-mediated NF-kB and C/EBP6 activation, ROS generation and AP-1/ HO-1 expression. Therefore, the present study indicated that MV has a significant chemopreventive effect on the inflammatory lesions and suggested that AKT1 is a potential specific target of MV for relieving inflammation. | Yong Li Luyan Zou Tao Li Dengni Lai Yanyang Wu Si Qin | 2019 | Acta Biochimica et Biophysica Sinica2019，51，4： | 14 |
| 4 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 5 | Dissecting and Enhancing the Contributions of High-Molecular-Weight Glutenin Subunits to Dough Functionality and Bread Quality显示文摘Dear Editor, Seed storage proteins (SSPs) are frequently important determinants of crop quality traits (Shewry and Casey,1999).Dissecting and enhancing the genetic contributions of individual SSPs to their target traits are essential for effectively improving crop quality attributes.However,such a task is often difficult to accomplish,because SSPs are frequently expressed from multigene families and exhibit strong allelic variation.Consequently,detailed knowledge of the function of individual SSPs in crop quality trait is still limited.This scenario is well illustrated by high-molecular-weight glutenin subunits (HMWGSs),a complex family of SSPs that are involved in wheat enduse quality through affecting dough functionality (Békés,2012;Rasheed et al.,2014). | Yiwen Li Xuefi An Ran Yang Xiaomin Guo Guidong Yue Renchun Fan Bin Li Zhensheng Li Kunpu Zhang Zhenying Dong Luyan Zhang Jiankang Wang Xu Jia Hong-Qing Ling Aimin Zhang Xiangqi Zhang Daowen Wang | 2015 | Molecular Plant2015，8，2： | 9 |
| 6 | R/S AND WAVELET ANALYSIS ON EVOLUTIONARYPROCESS OF REGIONAL ECONOMIC DISPARITY IN CHINA DURING PAST 50 YEARS显示文摘This paper shows the dynamic process of regional disparity of economic development in China in the past 50 years from a new insight by using the rescaled range statistic (R/S) analysis and wavelet analysis of the Theil index sequence with different time scales. The main conclusions are: 1) The regional disparity of economic development in China, including the inter-provincial disparity, inter-regional disparity and intra-regional disparity, has existed for many years. Theil index by the comparative price has revealed the true trend for comparative disparity of regional economic development from 1952 to 2000. 2) Decomposition of Theil index indicates that the dynamic trend of comparative inter-provincial disparity in the coastal region is in line with dynamic trend of inter-provincial disparity in the whole China. 3) The R/S analysis results tell us that during 1966-1978, the Hurst exponent H=0.504≈0.5, which indicates that in that period the evolution of comparative inter-provincial disparity of economic development showed a random characteristic, and in the other periods, i.e. 1952-1965, 1979-1990 and 1991-2000, the Hurst exponent H>0.5, which indicates that in those periods the evolution of the comparative inter-provincial disparity of economic development in China had a long-enduring characteristic. 4) By using wavelet analysis at different time scale, we arrived at a conclusion that the evolutionary process of the disparity of economic development of China is not a simple inverted U shape but a compound of several U shapes. The result tells us that the evolutionary plot of inter-provincial disparity in China follows the inverted U on the whole at the higher scale, 24(16 years). That is to say, the disparity tends to rise in the first stage of economic development, and fall slowly over the peak in the second stage of economic development. However, if we shorten the time scale to 23 (8 years), then a link of several U shapes will appear. | XUJian-hua LUYan SUFang-lin AINan-shan | 2004 | Chinese Geographical Science2004，14，3： | 9 |
| 7 | A polyoxometalate-functionalized two-dimensional titanium carbide composite MXene for effective cancer theranostics显示文摘作为一个新家庭二维(2D ) nanomaterials,因为高效, MXenes 最近包括精力在万用的应用吸引了许多注意存储和电气化学,而是他们到 biomedicine 的特定的申请很少被报导了特别为 theranostic nanomedicine,即,并发的诊断成像和治疗。这研究第一次显示出表面设计和 2D Ti 3 由 GdW 10-based polyoxometalates (POM ) 的集成的 C 2 MXene nanosheets。这些多功能的 GdW 10@Ti3 C 2 合成 nanosheets 向过高热的治疗提供磁性的回声(先生) 或计算断层摄影术(CT ) 向肿瘤房间或异种皮移植的成像指导。没有进一步的出现,一个肿瘤有效地在观察时期期间被根除。是综合的到 Ti 310 nanoclusters > C 2 nanosheets 被表明基于他们的唯一的作文为提高对比的 CT 和先生成像用作一个对比代理人,因此为诊断成像的指导显示出潜力并且为肿瘤过高热 nanotherapy 监视。在 GdW 10@Ti3 C 2 合成 nanosheets 被表明保证他们的随后的翻译进医疗。这研究为由表面工程和 multifunctionalization 拓宽 MXenes 的生物医学的应用提供新奇策略,它被期望在 nanotheranostics 支持 MXenes 的生物医学的应用的进一步的探索。 | Luyan Zong Huixia Wu Han Lin Yu Chen | 2018 | Nano Research2018，11，8： | 9 |
| 8 | The Statistical Power of Inclusive Composite Interval Mapping in Detecting Digenic Epistasis Showing Common F_2 Segregation Ratios显示文摘Epistasis is a commonly observed genetic phenomenon and an important source of variation of complex traits,which could maintain additive variance and therefore assure the long-term genetic gain in breeding.Inclusive composite interval mapping(ICIM) is able to identify epistatic quantitative trait loci(QTLs) no matter whether the two interacting QTLs have any additive effects.In this article,we conducted a simulation study to evaluate detection power and false discovery rate(FDR) of ICIM epistatic mapping,by considering F_2 and doubled haploid(DH) populations,different F_2 segregation ratios and population sizes.Results indicated that estimations of QTL locations and effects were unbiased,and the detection power of epistatic mapping was largely affected by population size,heritability of epistasis,and the amount and distribution of genetic effects.When the same likelihood of odd(LOD) threshold was used,detection power of QTL was higher in F_2 population than power in DH population;meanwhile FDR in F_2 was also higher than that in DH.The increase of marker density from 10 cM to 5 cM led to similar detection power but higher FDR.In simulated populations,ICIM achieved better mapping results than multiple interval mapping(MIM) in estimation of QTL positions and effect.At the end,we gave epistatic mapping results of ICIM in one actual population in rice(Oryza sativa L.). | Luyan Zhang Huihui Li Jiankang Wang | 2012 | Journal of Integrative Plant Biology2012，54，4： | 6 |
| 9 | Ordering of high-density markers by the k-Optimal algorithm for the traveling-salesman problem显示文摘Construction of accurate and high-density linkage maps is a key research area of genetics.We investigated the efficiency of genetic map construction(MAP)using modifications of the k-Optimal(k-Opt)algorithm for solving the traveling-salesman problem(TSP).For TSP,different initial routes resulted in different optimal solutions.The most optimal solution could be found only by use of as many initial routes as possible.But for MAP,a large number of initial routes resulted in one optimal order.k-Opt using open route length gave a slightly higher proportion of correct orders than the method of adding one virtual marker and using closed route length.Recombination frequency(REC)and logarithm of odds(LOD)score gave similar proportions of correct order,higher than that given by genetic distance.Both missing markers and genotyping error reduced ordering accuracy,but the best order was still achieved with high probability by comparison of the optimal orders from multiple initial routes.Computation time increased rapidly with marker number,and 2-Opt took much less time than 3-Opt.The 2-Opt algorithm was compared with ordering methods used in two other software packages.The best method was 2-Opt using open route length as the criterion to identify the optimal order and using REC or LOD as the measure of distance between markers.We describe a unified software interface for using k-Opt in high-density linkage map construction for a wide range of genetic populations. | Luyan Zhang Huihui Li Lei Meng Jiankang Wang | 2020 | The Crop Journal2020，8，5： | 6 |
| 10 | Linkage analysis and integrated software GAPL for pure-line populations derived from four-way and eight-way crosses显示文摘Pure lines derived from multiple parents provide abundant variation for genetic study.However,efficient genetic analysis methods and user-friendly software are still lacking.In this study, we developed linkage analysis methods and integrated analysis software for pure-line populations derived from four-way and eight-way crosses.First, polymorphic markers are classified into different categories according to the number of identifiable alleles in the inbred parents.Expected genotypic probability is then derived for each pair of complete markers, and based on them a maximum likelihood estimate(MLE) of recombination frequency is calculated.An EM algorithm is proposed for calculating recombination frequencies in scenarios that at least one marker is incomplete.A linkage map can thus be constructed using estimated recombination frequencies.We describe a software package called GAPL for recombination frequency estimation and linkage map construction in multi-parental pure-line populations.Both simulation studies and results from a reported four-way cross recombinant inbred line population demonstrate that the proposed method and software can build more accurate linkage maps in shorter times than other published software packages.The GAPL software is freely available from www.isbreeding.net and can also be used for QTL mapping in multi-parental populations. | Luyan Zhang Lei Meng Jiankang Wang | 2019 | The Crop Journal2019，7，3： | 5 |
| 11 | Protective effects of curcumin against human immunodeficiency virus 1 gp120 V3 loop-induced neuronal injury in rats显示文摘Curcumin improves the learning and memory deficits in rats induced by the gp120 V3 loop. The present study cultured rat hippocampal neurons with 1 nM gp120 V3 loop and 1 μM curcumin for 24 hours. The results showed that curcumin inhibited the gp120 V3 loop-induced mitochondrial membrane potential decrease, reduced the mRNA expression of the pro-apoptotic gene caspase-3, and attenuated hippocampal neuronal injury. | Zheng Gong Lijuan Yang Hongmei Tang Rui Pan Sai Xie Luyan Guo Junbin Wang Qinyin Deng Guoyin Xiong Yanyan Xing Jun Dong | 2012 | Neural Regeneration Research2012，7，3： | 5 |
| 12 | A Study of Estimation Model for the Chlorophyll Content of Wheat Leaf Based on Hyperspectral Imaging显示文摘In order to explore the spectral features and sensitive wave band of wheat leaf,we establish a quantitative relationship model between wheat chlorophyll content and spectral features to promote the application of hyperspectral technology in precise wheat fertilization and fast,non-destructive growth monitoring.Using the relational analysis,we analyze the relationship between chlorophyll content and spectral reflectance or the first derivative,and establish the chlorophyll content monitoring model.By selection and verification,the best estimation models for wheat chlorophyll content are as follows:SPAD = 36.75 + 188.168R387,SPAD =2094.242R'7153+ 112646.744 R'7152-1.561E7 R'715+42.991.The two models can well estimate the SPAD value of wheat leaf,and comparatively speaking,the SPAD estimation model based on wave band R387 has greater accuracy. | Luyan NIU Xiaoyan ZHANG | 2016 | Asian Agricultural Research2016，8，8： | 4 |
| 13 | Modeling and simulation of recurrent phenotypic and genomic selections in plant breeding under the presence of epistasis显示文摘Recurrent selection is an important breeding method for population improvement and selecting elite inbreds or fixed lines from the improved germplasm.Recently,a computer simulation tool called QuMARS has been developed,which allows the simulation and optimization of various recurrent selection strategies.Our major objective in this study was to use the QuMARS tool to compare phenotypic recurrent,marker-assisted recurrent,and genomic selections(abbreviated respectively as PS,MARS and GS)for both short-and long-termbreeding procedures.ForMARS,twomarker selection models were considered,i.e.,stepwise(Rstep)and forward regressions(Forward).For GS,three prediction models were considered,i.e.,genomic best linear unbiased predictors(GBLUP),ridge regression(Ridge),and regression by Moore-Penrose general inverse(InverseMP).To generate genotypes and phenotypes for a given individual during simulation,one additive and two epistasis genetic models were considered with three levels of heritability.Results demonstrated that selection responses from GBLUP-based GS and MARS(Forward)were consistently greater than those from PS under the additive model,particularly in early selection cycles.In contrast,selection response from PS was consistently superior over MARS and GS under epistatic models.For the two epistasis models,total genetic variance and the additive variance component were increased in some cases after selection.Through simulation,we concluded that GS and PS were effective recurrent selection methods for improved breeding of targeted traits controlled by additive and epistatic quantitative trait loci(QTL).QuMARS provides an opportunity for breeders to compare,optimize and integrate new technology into their conventional breeding programs. | Mohsin Ali Luyan Zhang Ian DeLacy Vivi Arief Mark Dieters Wolfgang H.Pfeiffer Jiankang Wang Huihui Li | 2020 | The Crop Journal2020，8，5： | 4 |
| 14 | Quantitative trait locus mapping with background control in genetic populations of clonal F_1 and double cross显示文摘In this study, we considered five categories of molecular markers in clonal F_1 and double cross populations,based on the number of distinguishable alleles and the number of distinguishable genotypes at the marker locus. Using the completed linkage maps, incomplete and missing markers were imputed as fully informative markers in order to simplify the linkage mapping approaches of quantitative trait genes. Under the condition of fully informative markers, we demonstrated that dominance effect between the female and male parents in clonal F_1 and double cross populations can cause the interactions between markers. We then developed an inclusive linear model that includes marker variables and marker interactions so as to completely control additive effects of the female and male parents, as well as the dominance effect between the female and male parents. The linear model was finally used for background control in inclusive composite interval mapping(ICIM) of quantitative trait locus(QTL). The ef ficiency of ICIM was demonstrated by extensive simulations and by comparisons with simple interval mapping, multiple-QTL models and composite interval mapping. Finally, ICIM was applied in one actual double cross population to identify QTL on days to silking in maize. | Luyan Zhang Huihui Li Junqiang Ding Jianyu Wu Jiankang Wang | 2015 | Journal of Integrative Plant Biology2015，57，12： | 4 |
| 15 | siRNA targeting stathmin inhibits invasion and enhances chemotherapy sensitivity of stem cells derived from glioma cell lines显示文摘Glioma 高度是大多数之一 angiogenic 肿瘤,和 glioma 干细胞(GSC ) 为到化疗和放射疗法的抵抗负责,以及在操作以后的复发。Stathmin 为有丝分裂是实质的并且在导出 glioma 的 endothelial 房间的增长和移植起一个重要作用。然而,在 stathmin 和 GSC 之间的关系不完全地被理解。这里,我们从 glioma 房间线 U87MG 和 U251 孤立 GSC,然后使用了为 silencing 指向 stathmin 的 siRNA。我们证明 stathmin 的 silencing 压制了增长,增加了 apoptosis 率,并且逮捕了在在 GSC 的 G2/M 阶段的房间周期。在 GSC 的 stathmin 的 Silencing 也导致了禁止了迁居 / 侵略以及 vasculogenic 的能力模仿。到 temozolomide 的 GSC 的危险性被 stathmin silencing 也提高。我们的调查结果为 glioma 处理在 GSC 作为一个潜在的目标建议 stathmin。 | Yuwen Song Luyan Mu Xuezhe Han Xiaoqian Liu Songbin Fu | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 4 |
| 16 | Rapid room-temperature synthesis of a porphyrinic MOF for encapsulating metal nanoparticles显示文摘While metal nanoparticles(NPs)have shown great promising applications as heterogeneous catalysts,their agglomeration caused by thermodynamic instability is detrimental to the catalytic performance.To tackle this hurdle,we successfully prepared a functional and stable porphyrinic metal-organic framework(MOF),PCN-224-RT,as a host for encapsulating metal nanoparticles by direct stirring at room temperature.As a result,Pt@PCN-224-RT composites with well-dispersed Pt NPs can be constructed by introducing pre-synthesized Pt NPs into the precursor solution of PCN-224-RT.Of note,the rapid and simple stirring method in this work is more in line with the requirements of environmental friendly and industrialization compared with traditional solvothermal methods. | Huihui He Luyan Li Yang Liu Meruyert Kassymova Dandan Li Liangliang Zhang Hai-Long Jiang | 2021 | Nano Research2021，14，2： | 3 |
| 17 | Estimation of statistical power and false discovery rate of QTL mapping methods through computer simulation显示文摘Many QTL mapping methods have been developed in the past two decades.Statistically,the best method should have a high detection power but a low false discovery rate (FDR).Power and FDR cannot be derived theoretically for most QTL mapping methods,but they can be properly evaluated using computer simulations.In this paper,we used four genetic models (two for independent loci and two for linked loci) to illustrate power and FDR estimation for interval mapping (IM) and inclusive composite interval mapping (ICIM).For each model,we simulated 1000 populations each of 200 doubled haploids.A support interval (SI) was first defined to indicate to which predefined QTL the significant QTL belonged.Power was calculated by counting the number of simulation runs with significant peaks higher than the logarithm of odds (LOD) threshold in the SI.Quantitative trait loci not identified in any SIs were viewed as false positives.The FDR is the rate at which QTLs are identified as significant when they are actually non-significant.Simulation results allowed us to estimate power and FDR of IM and ICIM for two independent and two linkage genetic models.Our estimates allowed us to readily compare the efficiencies of different statistical methods for QTL mapping,including the ability to separate linkage,under a wide range of genetic models.We used IM and ICIM as examples of how to estimate power and FDR,but the principles shown in this paper can be used for power analysis and comparison of any other QTL mapping methods,especially those based on interval tests. | LI HuiHui ZHANG LuYan WANG JianKang | 2012 | Chinese Science Bulletin2012，57，21： | 3 |
| 18 | One-dimensional/three-dimensional analysis of transient cavitating flow in a venturi tube with special emphasis on cavitation excited pressure fluctuation prediction显示文摘The large eddy simulation(LES) method is used to simulate cavitating flow in a venturi tube. The simulated results agree fairly well with the experimental data. To quantitatively describe the relationship between cavitation evolution and excited pressure fluctuation in the venturi tube, a modified prediction model is proposed and its accuracy is verified by the LES results. Based on the original one-dimensional model for the external cavitating flow around a hydrofoil, this model is corrected according to the internal cavitating flow characteristics in the venturi tube. The results show that the original one-dimensional model ignores the choking effect of cavitating flow, which is obvious in a venturi tube with a narrow flow channel, thus leading to an inaccurate prediction of pressure fluctuation in the venturi tube. The modified model can significantly overcome its deficiencies and improve the accuracy of the pressure fluctuation prediction, providing a theoretical basis and guidance for engineering application to controlling the pressure fluctuation in a venturi tube or for other internal flows. | WANG LuYan JI Bin CHENG HuaiYu WANG Jiong LONG XinPing | 2020 | Science China(Technological Sciences)2020，63，2： | 3 |
| 19 | Bosonic quantum error correction codes in superconducting quantum circuits显示文摘Quantum information is vulnerable to environmental noise and experimental imperfections,hindering the reli-ability of practical quantum information processors.Therefore,quantum error correction(QEC)that can pro-tect quantum information against noise is vital for universal and scalable quantum computation.Among many different experimental platforms,superconducting quantum circuits and bosonic encodings in superconducting microwave modes are appealing for their unprecedented potential in QEC.During the last few years,bosonic QEC is demonstrated to reach the break-even point,i.e.the lifetime of a logical qubit is enhanced to exceed that of any individual components composing the experimental system.Beyond that,universal gate sets and fault-tolerant operations on the bosonic codes are also realized,pushing quantum information processing towards the QEC era.In this article,we review the recent progress of the bosonic codes,including the Gottesman-Kitaev-Preskill codes,cat codes,and binomial codes,and discuss the opportunities of bosonic codes in various quantum applications,ranging from fault-tolerant quantum computation to quantum metrology.We also summarize the challenges associated with the bosonic codes and provide an outlook for the potential research directions in the long terms. | Weizhou Cai Yuwei Ma Weiting Wang Chang-Ling Zou Luyan Sun | 2021 | Fundamental Research2021，1，1： | 3 |
| 20 | NON-ZONAL BAROCLINIC INSTABILITY IN THE NORTH PACIFIC SUBTROPICAL COUNTERCURRENT显示文摘Observations indicated that in the region of the Subtropical Countercurrent (STCC) over the Pacific (140°E-170°W, 19°N-28°N), the eddy kinetic energy over the western side is much higher than that over the eastern side. The cause of such a behavior was theoretically investigated in this paper. The calculation of geostrophic current in this region indicates that there are relatively strong meridional geostrophic currents in this region even though the zonal current is dominant in most seasons. Using a 2.5-layer reduced-gravity model, baroclinic instability of non-zonal current was discussed. It is found that at the western side of STCC the vertical shear of the meridional geostrophic current will be in favor of the baroclinic instability, but at its eastern side it will suppress baroclinic instability, thus causing the growth of eddies over the western side much faster than that over the eastern side. | LUYan LUODe-hai | 2004 | Journal of Hydrodynamics2004，16，5： | 3 |
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