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| 1 | siRNA targeting stathmin inhibits invasion and enhances chemotherapy sensitivity of stem cells derived from glioma cell lines显示文摘Glioma 高度是大多数之一 angiogenic 肿瘤,和 glioma 干细胞(GSC ) 为到化疗和放射疗法的抵抗负责,以及在操作以后的复发。Stathmin 为有丝分裂是实质的并且在导出 glioma 的 endothelial 房间的增长和移植起一个重要作用。然而,在 stathmin 和 GSC 之间的关系不完全地被理解。这里,我们从 glioma 房间线 U87MG 和 U251 孤立 GSC,然后使用了为 silencing 指向 stathmin 的 siRNA。我们证明 stathmin 的 silencing 压制了增长,增加了 apoptosis 率,并且逮捕了在在 GSC 的 G2/M 阶段的房间周期。在 GSC 的 stathmin 的 Silencing 也导致了禁止了迁居 / 侵略以及 vasculogenic 的能力模仿。到 temozolomide 的 GSC 的危险性被 stathmin silencing 也提高。我们的调查结果为 glioma 处理在 GSC 作为一个潜在的目标建议 stathmin。 | Yuwen Song Luyan Mu Xuezhe Han Xiaoqian Liu Songbin Fu | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 4 |
| 2 | Experimental repetitive quantum channel simulation显示文摘Universal control of quantum systems is a major goal to be achieved for quantum information processing,which demands thorough understanding of fundamental quantum mechanics and promises applications of quantum technologies. So far, most studies concentrate on ideally isolated quantum systems governed by unitary evolutions, while practical quantum systems are open and described by quantum channels due to their inevitable coupling to environment. Here, we experimentally simulate arbitrary quantum channels for an open quantum system, i.e. a single photonic qubit in a superconducting quantum circuit.The arbitrary channel simulation is achieved with minimum resource of only one ancilla qubit and measurement-based adaptive control. By repetitively implementing the quantum channel simulation,we realize an arbitrary Liouvillian for a continuous evolution of an open quantum system for the first time. Our experiment provides not only a testbed for understanding quantum noise and decoherence,but also a powerful tool for full control of practical open quantum systems. | Ling Hu Xianghao Mu Weizhou Cai Yuwei Ma Yuan Xu Haiyan Wang Yipu Song Chang-Ling Zou Luyan Sun | 2018 | Science Bulletin2018，63，23： | 2 |
| 3 | Effects of Cracks on the Mass Transfer of Polymer Electrolyte Membrane Fuel Cell with High Performance Membrane Electrode Assembly显示文摘A two-dimensional geometric model is developed for a polymer electrolyte based on the liquid water penetration mechanism in the membrane electrode assemblies under the action of capillary pressure.The effects of the diameter,number,and distribution of cracks in the micro-pore layers(MPLs)of the modeled MEA on the performance of the PEMFC are simulated to investigate the influence of mass transfer across the membrane.The results indicate that liquid water in the catalyst layer(CL)of the MEA can be discharged to gas channels through the cracks in MEA under the action of capillary pressure,thereby alleviating the flooding in the CL and enhancing the diffusion of oxygen to the CL.When the proportion of the total area of cracks in the active area of the MEA was 8%-12%,crack diameter was 20-30μm,and cracks were distributed uniformly.MEAs with and without cracks were prepared,fuel cells were assembled,and their performance was measured.The effects of cracks on mass transfer were then verified.This study helps prepare MEAs with controllable cracks. | 施金蓉 詹志刚 ZHANG Di YU Yuan YANG Xiaoxiang HE Luyan PAN Mu | 2021 | Journal of Wuhan University of Technology(Materials Science)2021，36，3： | 1 |
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