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| 1 | The p53/miR-34 axis in development and disease显示文摘肿瘤 suppressor p53 是在人的癌症的最经常变异的基因之一。MicroRNAs (miRNAs ) 是在 post-transcriptional 水平上调整基因表示的小 non-proteincoding RNA。最近, p53 调整几 miRNAs 的 theexpression,这被显示出,从而代表 p53 发信号的重要机制。几个独立人士作为最流行的导致 p53 的 miRNAs 学习 miR-34 家庭的 identifiedthe 成员。miR-34s 经常是在 tumorentities 的变化的 silenced,建议他们是重要肿瘤 suppressors。确实, miR-34s 的宫外的表示禁止增长,对各种各样的癌症房间实体的间充质的转变,移植,侵略,和转移上皮。而且, miR-34 的 deliveryor 重新表示在癌症老鼠模型导致肿瘤生长和转移的著名压抑,并且可以 thereforerepresent 为未来癌症治疗学的有效策略。除他们在癌症的关键函数以外, themiR-34 家庭的成员也在精子发生,干细胞区别, neuronal 开发,老化,和 cardiovascularfunctions 起重要作用。因而, miR-34 也在各种各样的非癌的疾病被含有,例如大脑混乱,骨质疏松症,和心血管的复杂并发症。 | Matjaz Rokavec Huihui Li Longchang Jiang and Heiko Hermeking | 2014 | Journal of Molecular Cell Biology2014，8，3： | 27 |
| 2 | Vaterite or aragonite observed in the prismatic layer of freshwater-cultured pearls from South China显示文摘A prismatic layer is present in both freshwater-cultured pearls and seawater-cultured pearls. The phase structure of the prismatic layer of freshwater-cultured pearls is investigated for the first time and novel findings are reported in this paper. X-ray diffraction (XRD), optical microscopy (OM) and micro-infrared (IR) spectroscopy were used to characterize the crystallized layers of high and low-quality freshwater-cultured pearls. Results show that there is no calcite in the prismatic layer of freshwater-cultured pearls, which is different from what was found for seawater-cultured pearls. We found that an aragonite phase was present in the prismatic layer of high-quality freshwater-cultured pearls and that a vaterite or aragonite phase was present in low-quality pearls. Based on this study an internal factor that influences the quality of freshwater-cultured pearls is discussed. | Hongyan Ma Anan Su Beili Zhang Ru-Kang Li Longchang Zhou Baoli Wang | 2009 | Progress in Natural Science:Materials International2009，19，7： | 7 |
| 3 | Phyto-Toxicity of Chromium in Maize: Oxidative Damage, Osmolyte Accumulation, Anti-Oxidative Defense and Chromium Uptake显示文摘Agricultural production systems are immensely exposed to different environmental stresses in which heavy metal stress receives serious concerns. This study was conducted to explore the deleterious effects of different chromium(Cr) stress levels, i.e., 0, 30, 6090, 120, and 150 μmol L-1, on two maize genotypes, Wandan 13 and Runnong 35. Both genotypes were evaluated by measuring their growth and yield characteristics, Cr accumulation in different plant tissues, alterations in osmolyte accumulation, generation o reactive oxygen species(ROS), and anti-oxidative enzyme activity to scavenge ROS. The results showed that Cr stress decreased the leaf area, cob formation, 100-grain weight, shoot fresh biomass, and yield formation, while Cr accumulation in different maize tissues was found in the order of roots > leaves > stem > seeds in both genotypes. The increased Cr toxicity resulted in higher free proline soluble sugars and total phenolic contents, and lower soluble protein contents. However, enhanced lipid peroxidation was noticed in the forms of malondialdehyde, hydrogen peroxide(H2O2) and thiobarbituric acid reactive substance accumulation, and electrolyte leakage. The hyperactivity of superoxide dismutase, peroxidase, catalase, ascorbate peroxidase, especially glutathione peroxidase and glutathione reductase indicated that these anti-oxidative enzymes had a central role in protecting maize from Cr toxicity, especially for Wandan 13. Moreover, higher uptake and less translocation of Cr contents into the grains of Wandan 13 implied its importance as a potential candidate against soil Cr pollution. | Shakeel Ahmad ANJUM Umair ASHRAF Imran KHAN Mohsin TANVEER Muhammad SHAHID Abdul SHAKOOR WANG Longchang | 2017 | Pedosphere2017，27，2： | 3 |
| 4 | The potent different risk factors for cerebral infarction in young patients with and without type 2 diabetes: Subanalysis of the Young Cerebral Infarction Study (YCIS)显示文摘 | Bin Zhang Cong Gao Qinghua Hou Jianrui Yin Longchang Xie Shuxiang Pu Yonghong Yi Qingchun Gao | 2011 | Atherosclerosis2011，，1： | 3 |
| 5 | Correlation analysis between characteristics under gastroscope and image information of tongue in patients with chronic gastritis显示文摘OBJECTIVE:To explore the correlation between diagnostic information of tongue and gastroscopy results of patients with chronic gastritis.METHODS:Frequent pattern growth(FP-Growth),SPSS Modeler was used to analyze the correlation rules between the image information of tongue parameters and the characteristics of the stomach and duodenum seen under gastroscopy.RESULTS:Ranking in order of confidence:cyanotic tongue,slippery fur,yellow fur and spotted tongue were sequently associated with both gastric antrum mucosal hyperemia or edema and gastric antrum mucosal erythema/macula.L,one value of tongue coating color,which counted among(30,60),tooth-marked tongue and b,one value of tongue coating color,which counted in the range of(5,20)were sequently associated with gastric antrum mucosal erythema/macula.A,one value of tongue body color,which counted in the range of(0,20),was related to both gastric antrum mucosal hyperemia or edema and gastric antrum mucosal erythema/macula.a,one value of tongue coating color,which counted in the range of(15,35),was associated with gastric antrum mucosal erythema/macula.There are a total of 9 strong correlation rules.CONCLUSIONS:Cyanotic tongue,slippery fur,yellow fur,the CIE Lab value of tongue coating,a,the value of tongue body color,spotted tongue,and tooth-marked tongue are all related to the gastric antrum mucosal hyperemia or edema and gastric antrum mucosal erythema/macula.The conditions of gastric mucosa could be predicted by the examination of the above related image information of tongue. | SHANG Zimeng DU Zhengguang GUAN Bei JI Xingyu CHEN Longchang WANG Yongji MA Yun | 2022 | Journal of Traditional Chinese Medicine2022，42，1： | 2 |
| 6 | Demonstration of tantalum as a structural material for MEMS thermal actuators显示文摘This work demonstrates the processing,modeling,and characterization of nanocrystalline refractory metal tantalum(Ta)as a new structural material for microelectromechanical system(MEMS)thermal actuators(TAs).Nanocrystalline Ta films have a coefficient of thermal expansion(CTE)and Young’s modulus comparable to bulk Ta but an approximately ten times greater yield strength.The mechanical properties and grain size remain stable after annealing at temperatures as high as 1000°C.Ta has a high melting temperature(Tm=3017℃)and a low resistivity(ρ=20µΩcm).Compared to TAs made from the dominant MEMS material,polycrystalline silicon(polysilicon,Tm=1414℃,ρ=2000µΩcm),Ta TAs theoretically require less than half the power input for the same force and displacement,and their temperature change is half that of polysilicon.Ta TAs operate at a voltage 16 times lower than that of other TAs,making them compatible with complementary metal oxide semiconductors(CMOS).We selectα-phase Ta and etch 2.5-μm-thick sputterdeposited films with a 1μm width while maintaining a vertical sidewall profile to ensure in-plane movement of TA legs.This is 25 times thicker than the thickest reactive-ion-etchedα-Ta reported in the technical literature.Residual stress sensitivities to sputter parameters and to hydrogen incorporation are investigated and controlled.Subsequently,a V-shaped TA is fabricated and tested in air.Both conventional actuation by Joule heating and passive self-actuation are as predicted by models. | Longchang Ni Ryan M.Pocratsky Maarten P.de Boer | 2021 | Microsystems & Nanoengineering2021，7，1： | 2 |
| 7 | Case study of an Equatorial Plasma Bubble Event investigated by multiple ground-based instruments at low latitudes over China显示文摘Observational evidence is insufficient to understand how equatorial plasma bubbles(EPBs)form over low latitudes.The mechanism of plasma-density enhancement(formation of'plasma blobs')at low latitudes is in dispute.In this paper,we use data from multiple ground-based instruments(one all-sky airglow imager,five digisondes,and one Fabry–Perot interferometer)to investigate the evolution of an EPB event that occurred at low latitudes over China on the night of 06 December 2015(06-Dec-2015).We provide observational evidence that an enhanced equatorward wind most likely induced by a substorm could have initiated the Rayleigh–Taylor instability(RTI)that destabilized several EPB depletions in an upwelling region of a large-scale wave-like structure(LSWS)in the bottomside ionosphere.Those EPB depletions were forced to surge poleward,from nearly 10°to 19°magnetic latitude,two hours before midnight.Smaller-scale bifurcations evolved rapidly from tips of airglow depletions by a secondary E×B instability when the aforementioned substorm-induced southwestward wind blew through.During the growth phase of the EPB depletions,a westward polarization electric field inside the LSWS is likely to have compressed plasma downward,inducing the two airglow-type blobs observed in the bottomside ionosphere,by a mechanism of LSWS-blob connection that we propose.We also provide observational evidence of brightness airglow depletions.We find that an enhanced poleward wind associated with a passing-by brightness wave(BW)is likely to have transported plasma to fill the airglow depletions,which finally evolved into brightness airglow structures.This study investigates the physical processes accompanied by the EPB event and those two-airglow blobs observed at low-latitudes over China. | LongChang Sun JiYao Xu YaJun Zhu Wei Yuan XiuKuan Zhao | 2021 | Earth and Planetary Physics2021，5，5： | 1 |
| 8 | Different independent susceptibility markers for first-ever cerebral infarction and myocardial infarction in young patients显示文摘 | Bin Zhang Cong Gao Qinghua Hou Jianrui Yin Longchang Xie Shuxiang Pu Yonghong Yi Qingchun Gao | 2012 | Journal of Neurology2012，，： | 1 |
| 9 | Application of improved Sobel algorithm in medical image edge detection 显示文摘 | SHEN Dehai ZHANG Longchang | 2014 | Applied Mechanics and Materials2014，678，： | 1 |
| 10 | Hybrid-context-aware Web Service Selection Approach 显示文摘 | Zhang Longchang Qing Chu | 2013 | Journal of Internet Technology2013，14，1： | 1 |
| 11 | IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis显示文摘 | Rokavec Matjaz ?ner Meryem G?lfem Li Huihui Jackstadt Rene Jiang Longchang Lodygin Dmitri Kaller Markus Horst David Ziegler Paul K Schwitalla Sarah Slotta-Huspenina Julia Bader Franz G Greten Florian R Hermeking Heiko | 2014 | Journal of Clinical Investigation2014，，： | 1 |
| 12 | STUDY ON THE METHOD OF CONSTRUCTING VARIABLE-DENSITY YIELD TABLE显示文摘Growth of stand average DBH is discussed bassed on relationship between standgrowth and stand density.Growth equation of stand average DBH is fitted with data of 65 plotsand 130 stem analyses of site index 18 meter of old-growth Larch(Larix gmeliniiRupr.)collectedin Great Xing’an Mountain m Inner Monglia.Variable-density yield tables of old—growth Larchare constructed based on growth equation of stand average DBH and relationship between standaverage DBH and the other stand attributes. | Lee Longchang Hao Wenkang Weng Guoqing Northeast Forestry University | 1991 | Journal of Northeast Forestry University1991，2，2： | 1 |
| 13 | Non-invasive monitoring of blood pressure using the Philips Intellivue MP50 monitor cannot replace invasive blood pressure techniques in surgery patients under general anesthesia 显示文摘 | XIANGHU MENG GUANGHUI ZANG LONGCHANG FAN | 2013 | Experimental and Therapeutica medicine2013，6，1： | 1 |
| 14 | Morphologi-cal, physiological and biochemical responses of plants to droughtstress显示文摘 | Anjum S A Xie Xiaoyu Wang Longchang | 2011 | African Journal of Agricultural Research2011，6，9： | 1 |
| 15 | Observation of modulated spontaneous emission of Rhodamine 6G in low refractive index contrast 1D-periodic gelatin film显示文摘The modulation of the spontaneous emission of Rhodamine 6G has been observed in one-dimensional periodic dielectric structure of dichromated gelatin film with refractive index contrast as low as 0.01. The spontaneous emission is enhanced at the band edges and inhibits in the band gap, which agree well with the theoretical analysis on the redistribution of the fractional local density of optical states. | LI Wei 1 , ZHANG XinZheng 1 , WANG ZhenHua 1 , WU Qiang 1 , LIU LongChang 1 , XU JingJun 1 & Tang BaiQuan 2 1 The MOE Key Laboratory of Weak-Light Nonlinear Photonics, TEDA Applied Physics School, Nankai University, Tianjin 300457, China 2 School of Physics, Nankai University, Tianjin 300071, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，1： | 0 |
| 16 | 间隙连接蛋白connexin43在膀胱移行细胞癌组织中的表达及其与Bcl-2、Bax表达的相关性(英文)显示文摘Objective: To study the expression of connexin43 (Cx43) gene and its correlation with the apoptosis related genes Bcl-2 and Bax in transitional cell carcinoma of the bladder (BTCC), and to investigate the role of Cx43 in the BTCC. Methods: Reverse transcription polymerase chain reaction was used to detect the expression of Cx43 mRNA and immunocytochemistry technique was used to detect the expressions of Bcl-2 and Bax proteins in 60 cases of BTCC tissues, and compared with that of 15 cases of pericancerous tissues and 15 cases of normal bladder tissues. Results: The positive expression rate of Cx43 mRNA in 60 cases of BTCC tissues was 43.33% which was significantly lower than that in pericancerous tissues (73.33%) and normal tissues (100%) (χ2 = 17.58, P < 0.01). The expression of Cx43 had significant negative correlation with the pathological degree and lymph node metastasis of BTCC (χ2 = 9.33 and 9.74, respectively, P < 0.01). However, no correlation was found between the expression and patient sex, age, clinical staging and diameter and growth pattern of BTCC (P > 0.05). Expression of Cx43 negatively correlated with Bcl-2 protein (r = -0.63, P < 0.01) and positively correlated with Bax protein (r = 0.52, P < 0.01). Conclusion: The down-regulated expression of Cx43 gene was closely associated with the development, invasion and metastasis of BTCC. It could be used as a prognostic indicator for BTCC. Cx43 gene may have antagonistic effects with Bcl-2 gene and synergic with Bax gene in the initiation and progression of BTCC. | Zhengguo Cao Youwen Sun Ling Oi Longchang Fan Jun Xiao Linyu Zhou Yuping Zhu | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，6： | 0 |
| 17 | Considerations of the Economic Development in China’s Anddle-West Region显示文摘ConsiderationsoftheEconomicDevelopmentinChina’sAnddle-WestRegionZengTao;GaoLongchang(SoftScienceInstitute,SouthewestJiaatongU... | Zeng Tao Gao Longchang (Soft Science Institute, Southewest Jiaatong University) Chengdu 6 1 003 1, China | 1995 | Journal of Modern Transportation1995，12，2： | 0 |
| 18 | ON YIELD TABLE AND ITS GENERAL RESEARCH CONDITION IN CHINA显示文摘The development and rc research condition about yield table in China were in-troduced in this paper.Several methods of constructing yield table were also described and studied in brief. | WengGuoqing Chang Kun Forest Inventory and Planning Academy Hao Wenkang Zhang Yanli Northeast Forestry University Lcc Longchang Zhejiang Forestry Institutc | 1992 | Journal of Northeast Forestry University1992，3，2： | 0 |
| 19 | Plasmonic Cu_(27)S_(24)nanocages for novel solar photothermal nanoink and nanofilm显示文摘Copper sulfide(Cu_(x)S)as a plasmonic solar photothermal semiconductor material that expands the light collection range by altering localized surface plasmon resonance(LSPR)to the near-to mid-infrared(IR)spectral region.The versatile synthesis strategies of Cu_(x)S nanostructure offer its variability of morphology and provide additional freedom in tuning the optical property.Particularly,nanocage(or nanoshell)has hybridized plasmon resonances as a result of super-positioned nanosphere and nanocavity,which extends its receiving range of solar spectrum and increases light-to-heat conversion rate.Here,we offer novel“nanoink”and“nanofilm”developed from colloidal Cu_(27)S_(24)nanocages with excellent solar photothermal response.Via combining experimental measurement and theoretical calculation,we estimated the optical properties of covellite Cu_(27)S_(24).And based on obtained dielectric functions,we then calculated its solar photothermal performance,which was further validated by our experimental measurement.The simulation results showed that hollow Cu_(27)S_(24)nanocages have excellent solar photothermal performance,and exhibit much higher solar photothermal conversion efficiency than solid Cu_(27)S_(24)nanospheres. | Min Xi Longchang Xu Nian Li Shudong Zhang Zhenyang Wang | 2022 | Nano Research2022，15，4： | 0 |
| 20 | Modeling methodology and fault simulation of distribution networks integrated with inverter-based DG显示文摘The increasing penetration of inverter-based distributed generations(DGs)significantly affects the fault characteristics of distribution networks.Fault analysis is a keystone for suitable protection scheme design.This paper presents the modelling methodology for distribution networks with inverter-based DGs and performs fault simulation based on the model.Firstly,a single inverter-based DG model based on the cascaded control structure is developed.Secondly,a simulation model of distribution network with two inverter-based DGs is established.Then,different fault simulations are performed based on the Real Time Digital Simulator(RTDS).Theoretical analyses are conducted to justify the simulation results,including the equivalent circuit of distribution networks with inverter-based DGs and the solution method for loop currents. | Longchang Wang Houlei Gao Guibin Zou | 2017 | Protection and Control of Modern Power Systems2017，2，1： | 0 |
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