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| 1 | Impact of mechanical bowel preparation in elective colorectal surgery:A meta-analysis显示文摘AIM To analyse the effect of mechanical bowel preparation vs no mechanical bowel preparation on outcome in patients undergoing elective colorectal surgery.METHODS Meta-analysis of randomised controlled trials and observational studies comparing adult patients receiving mechanical bowel preparation with those receiving no mechanical bowel preparation, subdivided into those receiving a single rectal enema and those who received no preparation at all prior to elective colorectal surgery. RESULTS A total of 36 studies(23 randomised controlled trials and 13 observational studies) including 21568 patients undergoing elective colorectal surgery were included. When all studies were considered, mechanical bowel preparation was not associated with any significant difference in anastomotic leak rates(OR = 0.90, 95%CI: 0.74 to 1.10, P = 0.32), surgical site infection(OR = 0.99, 95%CI: 0.80 to 1.24, P = 0.96), intraabdominal collection(OR = 0.86, 95%CI: 0.63 to 1.17, P = 0.34), mortality(OR = 0.85, 95%CI: 0.57 to 1.27, P = 0.43), reoperation(OR = 0.91, 95%CI: 0.75 to 1.12, P = 0.38) or hospital length of stay(overall mean difference 0.11 d, 95%CI:-0.51 to 0.73, P = 0.72), when compared with no mechanical bowel preparation, nor when evidence from just randomized controlledtrials was analysed. A sub-analysis of mechanical bowel preparation vs absolutely no preparation or a single rectal enema similarly revealed no differences in clinical outcome measures. CONCLUSION In the most comprehensive meta-analysis of mechanical bowel preparation in elective colorectal surgery to date, this study has suggested that the use of mechanical bowel preparation does not affect the incidence of postoperative complications when compared with no preparation. Hence, mechanical bowel preparation should not be administered routinely prior to elective colorectal surgery. | Katie E Rollins Hannah Javanmard-Emamghissi Dileep N Lobo | 2018 | World Journal of Gastroenterology2018，24，4： | 33 |
| 2 | Renal oxidative vulnerability due to changes in mitochondrial - glutathione and energy homeostasis in a rat model of calcium oxalate urolithiasi显示文摘 | Meimaridou E Lobos E Hothersall JS | 2006 | Am J Physiol Renal Physiol2006，291，4： | 1 |
| 3 | The importance of diagnosing the polycystic ova- ry syndrome 显示文摘 | Lobo RA Carmina E | 2000 | Ann Intern Med2000，132，12： | 1 |
| 4 | Is there an association between low-to-moderate alcohol consumption and risk of cognitive decline显示文摘 | Lobo E Dufouil C Marcos G | 2010 | Am J Epidemiol2010，172，6： | 1 |
| 5 | A survey of optimization by building and using probabilistic models 显示文摘 | Pelikan M Goldberg D E and Lobo F G | 2002 | Computational Optimization and Applications2002，21，1： | 1 |
| 6 | Systemically administered a2-agonist-in-duced peripheral vasoconstriction in humans显示文摘 | Tallke PO Lobo E Brown R | 2003 | Anesthesiology2003，99，1： | 1 |
| 7 | Evaluation of alternative breeding programs for dual purpose zebu cattie显示文摘 | LOBO R N B MADALENA F E PENNA V M | 2000 | Rev Bras Zootec2000，29，5： | 1 |
| 8 | Inhibitory activity of Murraya paniculata Against Myotoxic Phospholipases A(2) 显示文摘 | LOBO E TATIANA PEREANEZ JAIME A ZAPATA A KAROL | 2010 | Vitae - Revista De La Facultad De Quimica Farmaceutica2010，17，3： | 1 |
| 9 | Genetic basis for in vivo daptomycin resistance in enterococci显示文摘 | Arias CA Panesso D McGrath DM Qin X Mojica MF Miller C Diaz L Tran TT Rincon S Barbu EM Reyes J Roh JH Lobos E Sodergren E Pasqualini R Arap W Quinn JP Shamoo Y Murray BE Weinstock GM | | 0，，： | 1 |
| 10 | Alpha-2B adrenoceptor polymorphism and peripheral vasoconstriction 显示文摘 | Talke P Stapelfeldt C Lobo E | 2005 | Pharmacogenet Genomics2005，15，5： | 1 |
| 11 | Whipple disease and central nervous system 显示文摘 | Abreu P Azevedo E Lobo L | 2005 | Acta Med Port2005，18，： | 1 |
| 12 | Use of fasting blood to assess the prevalence of insulin resistance in women with polycystic ovary syndrome显示文摘 | Carmina E Lobo RA | | 0，，03： | 1 |
| 13 | The diagnosis of polycystic ovary syndrome in adolescents显示文摘 | Carmina E Oberfield SE Lobo RA | 2010 | Am J Obstet Gynecol2010，203，3： | 1 |
| 14 | Zeolite and molecular sieve synthesis 显示文摘 | M E Davis R F Lobo | 1992 | Chem Mater1992，121，： | 1 |
| 15 | Duloxetine : clinical pharmacokinetics and drug interactions 显示文摘 | Knadler MP Lobo E Chappell J | 2011 | Clin Pharmacokinet2011，50，29： | 1 |
| 16 | The compact genetic algorithm 显示文摘 | HARIK G R LOBO F G GOLDBERG D E | 1999 | IEEE Tram on Evolutionary Computation1999，3，4： | 1 |
| 17 | Do hyperandrogenie women with normal menses have polycystic ovary syndrome? 显示文摘 | Carmina E Lobo RA | 1999 | Fertil Steril1999，71，2： | 1 |
| 18 | The ammonia selective catalytic reduction activity of copper-exchanged small-pore zeolites显示文摘 | FICKEL D W ADDIO E D LAUTERBACH J A LOBO R F | 2011 | Appl Catal B: Environ2011，102，34： | 1 |
| 19 | Systemically administered alpha2-agonist-induced peripheral vasoconstriction in humans显示文摘 | Talke P Lobo E Brown R | 2003 | Anesthesiology2003，99，1： | 1 |
| 20 | 显示文摘 | Davis M E | 1994 | Microporous Mater1994，2，： | 1 |
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