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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | Relations of hyperuricemia to longitudinal blood pressure tracking and hypertension incidence显示文摘 | Johan Sundstrom Lisa Sullivan Ralph B | 2005 | Hypertension2005，45，： | 1 |
| 3 | Inflammatory marlers and risk of heart failure in elderly subjects without prior myocardial infarction: The Framingham Heart Study显示文摘 | Vasan Ramachandran S Sullivan Lisa M Roubenoff Ronenn etal | 2003 | Circulation2003，107，11： | 1 |
| 4 | Plasma homocysteine, hypertension incidence, ans blood pressure tracking: The Framingham heart study显示文摘 | Sundstrom johan Sullivan Lisa D A gostino Ralph B | 2003 | Hypertension2003，42，6： | 1 |
| 5 | Relations of Serum Uric Acid to Longitudinal Blood Pressure Tracking and Hypertension Incidence显示文摘 | Johan Sundstr?m Lisa Sullivan Ralph B. D’Agostino Daniel Levy William B. Kannel Ramachandran S. Vasan | 2005 | Hypertension2005，，1： | 1 |
| 6 | The significant effect of diabetes duration on coronary heart disease mortality显示文摘 | Caroline S Lisa Sullivan Ralph B | 2004 | Diabetes Care2004，27，： | 1 |
| 7 | Predictors of Change in Pain and Physical Functioning Among Post-Menopausal Women With Recurrent Pain Conditions in the Women’s Health Initiative Observational Cohort显示文摘 | Jennifer Brennan Braden Alicia Young Mark D. Sullivan Brian Walitt Andrea Z. LaCroix Lisa Martin | 2012 | Journal of Pain2012，，： | 1 |
| 8 | A Method for Constructing a Social Vulnerability Index: An Application to Hurricane Storm Surges in a Developed Country显示文摘 | Lisa Rygel David O’sullivan Brent Yarnal | 2006 | Mitigation and Adaptation Strategies for Global Change2006，，3： | 1 |
| 9 | Inflammatory marles and risk of heart failure in elderly subjects without prior myocardial infarction : The Framingham Heart Study显示文摘 | Vasan Ramachandran S Sullivan Lisa M Roubenoff Ronenn | 2003 | Circulation2003，107，11： | 1 |
| 10 | Plasma homocysteine, hypertension incidence, and Blood pressure tracking:The Framingham heart study显示文摘 | Sullivan Lisa D'Agostino Ralph B | 2003 | Hypertension2003，42，6： | 1 |
| 11 | Association of Sex Hormones, Aging, and Atrial Fibrillation in Men: The Framingham Heart Study显示文摘 | Jared W. Magnani Carlee B. Moser Joanne M. Murabito Lisa M. Sullivan Na Wang Patrick T. Ellinor Ramachandran S. Vasan Emelia J. Benjamin Andrea D. Coviello | 2014 | Circulation: Arrhythmia and Electrophysiology2014，，2： | 1 |
| 12 | Metabolic Syndrome as a Precursor of Cardiovascular Disease and Type 2 Diabetes Mellitus显示文摘 | Peter W.F. Wilson Ralph B. D’Agostino Helen Parise Lisa Sullivan James B. Meigs | 2005 | Circulation2005，，20： | 1 |
| 13 | A Method for Constructing a Social Vulnerability Index: An Application to Hurricane Storm Surges in a Developed Country显示文摘 | Lisa Rygel David O’sullivan Brent Yarnal | 2006 | Mitigation and Adaptation Strategies for Global Change2006，，3： | 1 |
| 14 | Plasma homocysteine, hypertension incidence, and Blood pres- sure tracking: The Framingham heart study显示文摘 | Sundstrom Johan Sullivan Lisa D' Agostino RalPh B | 2003 | HyPertension2003，42，6： | 1 |
| 15 | BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly显示文摘 | Tomomi Kuwana Lisa Bouchier-Hayes Jerry E. Chipuk Christine Bonzon Barbara A. Sullivan Douglas R. Green Donald D. Newmeyer | 2005 | Molecular Cell2005，，4： | 1 |
| 16 | LDL particle number and risk of future cardiovascular disease in the Framingham Offspring Study—Implications for LDL management显示文摘 | William C. Cromwell James D. Otvos Michelle J. Keyes Michael J. Pencina Lisa Sullivan Ramachandran S. Vasan Peter W.F. Wilson Ralph B. D'Agostino | 2007 | Journal of Clinical Lipidology2007，，6： | 1 |
| 17 | Patterns of proton pump inhibitor use in clinical practice显示文摘 | Adam F Barrison Linda A Jarboe Benjamin M Weinberg Kiran Nimmagadda Lisa M Sullivan M.Michael Wolfe | 2001 | The American Journal of Medicine2001，，： | 1 |
| 18 | Relations of Biomarkers of Distinct Pathophysiological Pathways and Atrial Fibrillation Incidence in the Community显示文摘 | Renate B. Schnabel Martin G. Larson Jennifer F. Yamamoto Lisa M. Sullivan Michael J. Pencina James B. Meigs Geoffrey H. Tofler Jacob Selhub Paul F. Jacques Philip A. Wolf Jared W. Magnani Patrick T. Ellinor Thomas J. Wang Daniel Levy Ramachandran S. Vasan | 2010 | Circulation2010，，2： | 1 |
| 19 | Zirconium tungstate(ZrW2O8)/Polyimide nanocomposites exhibiting reduced coefficient of thermal expansion显示文摘 | Sullivan Lisa M Lukehart Charles M | 2005 | Chem Mater2005，17，： | 1 |
| 20 | Plas- real homoeysteine, hypertension incidence, and Blood pressure tracking: The Framingham heart study 显示文摘 | Sundstrom Johan Sullivan Lisa D' Agostino Ralph B | 2003 | Hypertersion2003，42，6： | 1 |
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