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| 1 | Development of 3D bioprinting:From printing methods to biomedical applications显示文摘Biomanufacturing of tissues/organs in vitro is our big dream,driven by two needs:organ transplantation and accurate tissue models.Over the last decades,3D bioprinting has been widely applied in the construction of many tissues/organs such as skins,vessels,hearts,etc.,which can not only lay a foundation for the grand goal of organ replacement,but also be served as in vitro models committed to pharmacokinetics,drug screening and so on.As organs are so complicated,many bioprinting methods are exploited to figure out the challenges of different applications.So the question is how to choose the suitable bioprinting method?Herein,we systematically review the evolution,process and classification of 3D bioprinting with an emphasis on the fundamental printing principles and commercialized bioprinters.We summarize and classify extrusion-based,dropletbased,and photocuring-based bioprinting methods and give some advices for applications.Among them,coaxial and multi-material bioprinting are highlighted and basic principles of designing bioinks are also discussed. | Zeming Gu Jianzhong Fu Hui Lin Yong He | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，5： | 11 |
| 2 | Why choose 3D bioprinting?Part II:methods and bioprinters显示文摘Classification of 3D bioprinting As we mentioned in the last editorial,3D printing,also known as additive manufacturing,could be considered as the reverse process of potato cutting,automatically assembling sliced potato,shredded potato,diced potato to integrity[1].Generally speaking,cell-laden 3D bioprinting can be classified into three types:extrusion-based,droplet-based and photocuring-based bioprinting according to different printing principles.Extrusion-based bioprinting squeezes out continuous hydrogel fibers to set up structures;dropletbased bioprinting generates droplets as the basic unit for biofabrication;and photocuring-based bioprinting utilizes the characteristics of light-sensitive materials,to stack 3D models layer-by-layer.Different bioprinting approaches own diverse characteristics facing various scenarios and have specific requirements for bioinks. | Yong He Zeming Gu Mingjun Xie Jianzhong Fu Hui Lin | 2020 | Bio-Design and Manufacturing2020，3，1： | 2 |
| 3 | Serum metabolomics reveals the deregulation of fatty acids metabolism in hepatocellular carcinoma and chronic liver diseases显示文摘 | Lina Zhou Quancai Wang Peiyuan Yin Wenbin Xing Zeming Wu Shili Chen Xin Lu Yong Zhang Xiaohui Lin Guowang Xu | 2012 | Analytical and Bioanalytical Chemistry2012，，1： | 2 |
| 4 | A tumor-targeting nano doxorubicin delivery system built from amphiphilic polyrotaxane-based block copolymers显示文摘 | Jiang Lan Gao Zeming Ye Lin | 2013 | Polymer2013，54，19： | 1 |
| 5 | An automatic registration algorithm for the scattered point clouds based on the curvature feature显示文摘 | He Bingwei Lin Zeming Li YF | 2013 | Optics & Laser Technology2013，46，： | 1 |
| 6 | Serum metabolomics reveals the deregulation of fatty acids metabolism in hepatocellular carcinoma and chronic liver diseases显示文摘 | Lina Zhou Quancai Wang Peiyuan Yin Wenbin Xing Zeming Wu Shili Chen Xin Lu Yong Zhang Xiaohui Lin Guowang Xu | 2012 | Analytical and Bioanalytical Chemistry2012，，1： | 1 |
| 7 | An automatic registration algorithm for the scattered point clouds based on the curvature feature显示文摘 | Bingwei He Zeming Lin Y.F. Li | 2013 | Optics and Laser Technology2013，，： | 1 |
| 8 | Embedding Pd-Cu Alloy Nanoparticles in Shell of Surface-Porous N-Doped Carbon Nanosphere for Selective Hydrogenation of p-Chloronitrobenzene显示文摘Main observation and conclusion A catalyst PdxCuy/NC in which Pd-Cu alloy nanoparticles are superficially embeded in shell of surface-porous N-doped carbon nanosphere was successfully devised for p-chloronitrobenzene(p-CNB)selective hydrogenation.Bimetal ions were loaded in shell of a m-phenylenediamine derived core-shell polymer sphere and the catalyst was obtained after calcination under reducing atmosphere.The as synthesized catalyst exhibited high selectivity in hydrogenation of p-CNB to p-chloroaniline(p-CAN)(up to 98.8%)under full conversion and the performance was basically remained after 6 cyclic experiments.The reasons for the high selectivity were discussed based on the characterization results of catalyst.The interaction between N-doped support and metal atoms affected the electron distribution in alloy,electron-deficient Pd and electron-rich Cu,and thus improved hydrogenation selectivity.In addition,the alloy nanoparticles were distributed only in the porous shell of support,which benefits to prevent side reactions.This work described a scheme for tactfully designing catalyst for selective hydrogenation,which can provide experience and inspiration for relevant works and fields. | Yingcen Liu Wanyue Ye Hua Lin Caicheng Song Zeming Rong Rongwen Lu Hao Zhang He Huang Zhicheng Tang Shufen Zhang | 2021 | Chinese Journal of Chemistry2021，39，10： | 0 |
| 9 | Immunization with recombinant baculovirus expressing the VP6 protein of grass carp reovirus induces immunity in grass carp显示文摘Dear Editor,Grass carp reovirus(GCRV),a member of the genus Aquareovirus in the family Reoviridae(Attoui H,et al,2002),is one of the most virulent aquareoviruses iden-tified so far,leading to high fatality rates(up to 85%)of fingerlings and yearlings of grass carp(Fang Q,et al,2007).No commercial vaccines against GCRV infection have been developed as yet. | Qin Li Liyue Liu Li Lin Zeming Li Guangxin Liu Shusheng Wu Min Wang Lijuan Li Junfa Yuan Gailing Yuan Xueqin Liu | 2014 | Virologica Sinica2014，29，4： | 0 |
| 10 | 细胞核内病毒RNA受体SAFA连接天然免疫和染色质重塑显示文摘文章简介天然免疫免疫从上世纪发现模式识别受体在现在一直学界研究的热点,而细胞核内的天然免疫识别和调节机制还不为人所知。本研究揭示了SAFA作为一个新型的细胞核内病毒双链RNA(dsRNA)监测器,连接染色质重塑和抗病毒天然免疫反应。该研究显示多种病毒感染宿主细胞后,在细胞核中产生dsRNA,被SAFA监测结合,引起SAFA发生寡聚化。 | Lili Cao Shengde Liu Yunfei Li Guang Yang Yujie Luo Siji Li Hongqiang Du Yingchi Zhao Dandan Wang Jingxuan Chen Zeming Zhang Mo Li Songying Ouyang Xiang Gao Yujie Sun Zekun Wang Long Yang Rongtuan Lin Penghua Wang 游富平 | 2020 | 科学新闻2020，，2： | 0 |
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