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| 1 | Possible mechanism underlying analgesic effect of Tuina in rats may involve piezo mechanosensitive channels within dorsal root ganglia axon显示文摘OBJECTIVE: To demonstrate the analgesic effect of Tuina mainly from mechanically sensitive ion channels in peripheral myelinated nerve fibers.METHODS: A total of 40 healthy and pathogen-free adult male Sprague-Dawley rats were used in the study [weight:(220.0 ± 1.4) g, Shanghai Slac Laboratory Animal Co., Ltd., Shanghai, China; license No. Shanghai ICP 05033115]. The rats were housed in cages with free access to water and food in a temperature-controlled room [(22 ± 1) ℃] and12-h/12-h light-dark cycle. Thirty-two rats were randomly divided into five groups: naive, sham, chronic compression of dorsal root ganglion(CCD), Tuina(7 d) and Tuina(21 d). CCD rat model was established via unilateral DRG compression by'L'liked steel bar. Chinese Tuina treatment was accepted once per day. Behavior monitoring of paw withdrawal threshold(PWT) and paw withdrawal latency(PWL) were tested. The expression of Piezo1 and Piezo2 in myelinated nerve fiber were analyzed by immunohistochemistry and Western-blotting.RESULTS: There was a high expression of Piezo2 and a low expression of Piezo1 in the naive and CCD groups. In contrast, the expression of Piezo2 was down regulated and Piezo1 was increased after a period of Tuina. There was significant difference(P ≤ 0.05) between the groups.CONCLUSION: Our findings suggest that Tuina therapy can increase the expression of Piezo2 and decrease the expression of Piezo1 in the test rats.The different changes in the expressions of Piezo1 and Piezo2 may play an important role in alleviating CCD-induced allodynia and hyperalgesia. | Song Pengfei Lin Zhigang Zhu Qingguang Jiang Shichao Zhang Hao Cheng Yanbin Sun Wuquan Wu Zhiwei Zhou Xin Lv Zhizhen Fang Min | 2018 | Journal of Traditional Chinese Medicine2018，38，6： | 6 |
| 2 | CHARACTERISTICS OF DROPLET TRANSFER IN CO_2 LASER-MIG HYBRID WELDING WITH SHORTCIRCUITING MODE显示文摘有 4.5 公里厚度的 LF6 铝合金盘子在这个实验被焊接。焊接被使用 CO_2 激光执行 -- 米格式飞机同等在扁平的位置的轴的混合焊接。试验性的结果显示常规米格式飞机弧的固有的微滴转移周期时间在激光的电路 theshort 模式由于在 CO_2 激光横梁和米格式飞机弧之间的相互作用被改变 -- 焊接的米格式飞机混血儿。因为到电极和基础材料的 CO_2 激光的预热行动,米格式飞机弧的微滴转移频率在混合焊接进程被增加。当激光力量被增加到某个度时,微滴转移频率由于导致激光的锁眼的效果被减少。而且,通过分析 MIGwelding 电流和弧电压,波形和微滴的特征在微滴转移的频率上在混合焊接过程,激光精力的效果和在激光横梁和弧之间的行动点转,焊接外观在细节被调查。 | LEI Zhenglong CHEN Yanbin LI Liqun WU Lin | 2006 | Chinese Journal of Mechanical Engineering2006，19，2： | 3 |
| 3 | A microfluidic biosensor for rapid detection of Salmonella typhimurium based on magnetic separation,enzymatic catalysis and electrochemical impedance analysis显示文摘Rapid screening of foodborne pathogens is of great significance to ensure food safety.A microfluidic biosensor based on immunomagnetic separation,enzyme catalysis and electrochemical impedance analysis was developed for rapid and sensitive detection of S.typhimurium.First,the bacterial sample,the magnetic nanoparticles(MNPs)modified with capture antibodies,and the enzymatic probes modified with detection antibodies and glucose oxidase(GOx)were simultaneously injected into the microfluidic chip,followed by mixing and incubation to form MNP-bacteria-probe sandwich complexes.Then,glucose with high impedance was injected into the chip and catalyzed by the GOx on the complexes into hydrogen peroxide with high impedance and gluconic acid with low impedance,which was finally measured using the low-cost interdigitated microelectrode and the electrochemical impedance analyzer to determine the target bacteria.Under the optimal conditions,this biosensor could quantitatively detect S.typhimurium at the concentrations from 1.6×10^(2) CFU/m L to 1.6×10^(6) CFU/m L in 1 h with the low detection limit of 73 CFU/m L.Besides,this biosensor was demonstrated with good feasibility for practical applications by detecting the S.typhimurium spiked chicken meat samples. | Yingjia Liu Dong Jiang Siyuan Wang Gaozhe Cai Li Xue Yanbin Li Ming Liao Jianhan Lin | 2022 | Chinese Chemical Letters2022，33，6： | 3 |
| 4 | A portable viable Salmonella detection device based on microfluidic chip and recombinase aided amplification显示文摘creening of foodborne pathogens is important to prevent contaminated foods from their supply chains.n this study, a portable detection device was developed for rapid, sensitive and simple detection of viable almonella using a finger-actuated microfluidic chip and an improved recombinase aided amplification (RAA) assay. Improved propidium monoazide(PMAxx) was combined with RAA to enable this device to distinguish viable bacteria from dead ones. The modification of PMAxx into dead bacteria, the magnetic xtraction of nucleic acids from viable bacteria and the RAA detection of extracted nucleic acids were performed using the microfluidic chip on its supporting device by finger press-release operations. The fluorescent signal resulting from RAA amplification of the nucleic acids was collected using a USB camera nd analyzed using a self-developed smartphone App to quantitatively determine the bacterial concenration. This device could detect Salmonella typhimurium in spiked chicken meats from 1.3 × 10^(2) CFU/m L o 1.3 × 10^(7) CFU/m L in 2 h with a lower detection limit of 130 CFU/m L, and has shown its potential for on-site detection of foodborne pathogens. | Wuzhen Qi Siyuan Wang Lei Wang Xinge Xi Shangyi Wu Yanbin Li Ming Liao Jianhan Lin | 2023 | Chinese Chemical Letters2023，34，2： | 2 |
| 5 | Enhancing the stability of astaxanthin by encapsulation in poly (1-lactic acid) microspheres using a supercritical anti-solvent process显示文摘To improve the physicochemical properties of astaxanthin, it was encapsulated in poly (1-lactic acid)(PLLA) using a supercritical anti-solvent (SAS) process with dichloromethane/acetone mixture as the solvent, and supercritical CO2 as the anti-solvent. The effects of altering five SAS operating cond让ions, solvent ratio, temperature, pressure, concentration of carrier, and flow rate, on the microstructure of particles were investigated using an orthogonal experimental design. Under the optimal conditions, astaxanthin/PLLA particles were produced with an encapsulation efficiency of 91.5% and a mean particle size of 954.6 nm. SEM images showed that most astaxanthin/PLLA particles were uniform microspheres. FT-IR spectra showed that the chemical structure of astaxanthin was unchanged by the SAS process. The results of chromatic difference, X-ray diffraction, thermogravimetric, and differential scanning calorimetry analyses showed that astaxanthin had been encapsulated in the PLLA matrix in an amorphous state. Overall, astaxanthin/PLLA microspheres greatly enhanced the stability of astaxanthin during storage, and the levels of residual solvents were far lower than the ICH lim让s. This means that astaxanthin/PLLA microspheres prepared using SAS show great potential for use in many food, cosmetic, and pharmaceutical formulations. | Guijin Liu Man Hu Ziyi Zhao Qing Lin Dongwei Wei Yanbin Jiang | 2019 | Particuology2019，17，3： | 2 |
| 6 | Time-Like Conformal Homogeneous Hypersurfaces with Three Distinct Principal Curvatures显示文摘A hypersurface x(M)in Lorentzian space R41 is called conformal homogeneous,if for any two points p,q on M,there exists,a conformal transformation of R41,such that(x(M))=x(M),(x(p))=x(q).In this paper,the authors give a complete classifica-tion for regular time-like conformal homogeneous hypersurfaces in R41 with three distinct principal curvatures. | Yanbin LIN Ying LU Changping WANG | 2020 | Chinese Annals of Mathematics,Series B2020，41，5： | 2 |
| 7 | Highly stable lithium anode enabled by self-assembled monolayer of dihexadecanoalkyl phosphate显示文摘Li has been considered as the ultimate anode material for high energy density secondary Li batteries.However,its practical application has been limited due to its low Coulombic efficiency(CE)and the formation of lithium dendrites.Recently,we have developed a microspherical Li-carbon nanotube(Li-CNT)composite material passivated with octadecylphosphonic acid(OPA)self-assembled monolayer(SAM)exhibiting suppressed lithium dendrite formation and improved environmental/electrochemical stability.In this work,we demonstrated the significantly enhanced passivation effects of a SAM using dihexadecanoalkyl phosphate(DHP),a molecule that is comprised of double hydrophobic alkyl chains and forms a denser SAM on surfaces with large curvature.As a result,the DHP SAM delivers superior environmental and electrochemical stability to the OPA passivated Li-CNT material.In specific,the DHP passivated Li-CNT composite(DHP-Li-CNT)delivers a high CE of 99.25%under a 33.3%depth of discharge(DOD)at 1 C,when it is paired with a LiFePO4 cathode.The evolution of the SAM during cycling and the effects of DOD and current density on the CE of the DHP-Li-CNT anode have also been investigated.The improved SAM passivation constitutes an important step in achieving the goal of practically applicable Li anodes. | Lei Zheng Feng Guo Tuo Kang Jin Yang Ya Liu Wei Gu Yanfei Zhao Hongzhen Lin Yanbin Shen Wei Lu Liwei Chen | 2020 | Nano Research2020，13，5： | 1 |
| 8 | Achieving high-capacity and long-life K^(+)storage enabled by constructing yolk-shell Sb_(2)S_(3)@N,S-doped carbon nanorod anodes显示文摘As promising anode candidates for potassium-ion batteries(PIBs),antimony sulfide(Sb_(2)S_(3))possesses high specific capacity but suffers from massive volume expansion and sluggish kinetics due to the large K^(+)insertion,resulting in inferior cycling and rate performance.To address these challenges,a yolk-shell structured Sb_(2)S_(3)confined in N,S co-doped hollow carbon nanorod(YS-Sb_(2)S_(3)@NSC)working as a viable anode for PIBs is proposed.As directly verified by in situ transmission electron microscopy(TEM),the buffer space between the Sb_(2)S_(3)core and thin carbon shell can effectively accommodate the large expansion stress of Sb_(2)S_(3)without cracking the shell and the carbon shell can accelerate electron transport and K^(+)diffusion,which plays a significant role in reinforcing the structural stability and facilitating charge transfer.As a result,the YS-Sb_(2)S_(3)@NSC electrode delivers a high reversible K^(+)storage capacity of 594.58 m A h g^(-1)at 0.1 A g^(-1)and a long cycle life with a slight capacity degradation(0.01%per cycle)for 2000 cycles at 1 A g^(-1)while maintaining outstanding rate capability.Importantly,utilizing in in situ/ex situ microscopic and spectroscopic characterizations,the origins of performance enhancement and K^(+)storage mechanism of Sb_(2)S_(3)were clearly elucidated.This work provides valuable insights into the rational design of high-performance and durable transition metal sulfides-based anodes for PIBs. | Bensheng Xiao Hehe Zhang Zhefei Sun Miao Li Yingzhu Fan Haichen Lin Haodong Liu Bing Jiang Yanbin Shen Ming-Sheng Wang Meicheng Li Qiaobao Zhang | 2023 | Journal of Energy Chemistry2023，，1： | 1 |
| 9 | The human REV1 gene codes for a DNA template- dependent dCMP transferase显示文摘 | Wensheng Lin Hua Xin Yanbin Zhang | 1999 | Nucleic Acids Res1999，27，22： | 1 |
| 10 | The FEM simulation of the temperature field in laser forming 显示文摘 | Chen Yanbin Li liqun Lin Shangyang | 2001 | Applied Laser2001，，2： | 1 |
| 11 | 1 H NMR-based spectroscopy detects metabolic alterations in serum of patients with early-stage ulcerative colitis显示文摘 | Ying Zhang Lianjie Lin Yanbin Xu Yan Lin Yu Jin Changqing Zheng | 2013 | Biochemical and Biophysical Research Communications2013，，4： | 1 |
| 12 | Evaluation of protective effect of multi-epitope DNA vaccine encoding six antigen segments of Toxoplasma gondii in mice显示文摘 | Liu Shan Shi Lin Chang Yanbin | | 0，，01： | 1 |
| 13 | Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting显示文摘Therapeutic efficacy against cancer relies heavily on the ability of the therapeutic agents to reach their final targets.The optimal targets of most cancer therapeutic agents are usually biological macromolecules at the subcellular level,which play a key role in carcinogenesis.Therefore,to improve the therapeutic efficiency of drugs,researchers need to focus on delivering not only the therapeutic agents to the target tissues and cells but also the drugs to the relevant subcellular structures.In this review,we discuss the most recent construction strategies and release patterns of various cancer cell subcellular-targeting nanoformulations,aiming at providing guidance in the overall design of precise nanomedicine.Additionally,future challenges and potential perspectives are illustrated in the hope of enhancing anticancer efficacy and accelerating the translational progress of precise nanomedicine. | Xianglei Fu Yanbin Shi Tongtong Qi Shengnan Qiu Yi Huang Xiaogang Zhao Qifeng Sun Guimei Lin | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 14 | New design method of unequal taper thread(UTT)pairs and its application in API NC38 thread improvement显示文摘API standard threads are the most commonly used thread configurations for drill pipe joints in the petroleum industry.Recently with the increasing application of horizontal wells and extended-reach wells in drilling engineering,drill pipe joint threads are subjected to complex loads,and drill pipe joint thread breakage accidents occur frequently.The API NC38 threaded pair used in the SU36-8-4H2 well suffered a fracture accident.Macroscopic analysis found that the fracture sites were located near the root of the first engagement pin-thread where the stress was greatest.Therefore,it is necessary to find an alternative method to reduce the largest stress of NC38 threads.Then,a new design method of unequal taper thread(UTT)pairs is proposed that the taper of pin thread,slightly smaller than the taper of matched-box thread,is not equal to one of box-thread.In the UTT pairs of API NC38 thread,the taper of box thread is kept as the standard taper of 1:6,but the taper of pin thread is,respectively,1:6.1(UTT-I),1:6.2(UTT-Ⅱ),1:6.3(UTT-Ⅲ)and 1:6.4(UTT-IV).The 3D finite element models of four UTT pairs and one standard pair based on NC38 thread were developed,and the mechanical properties of five thread pairs bearing such typical working loads as torque,axial compression,axial tension,bending moment,internal and external pressure,were analyzed.The results show that four UTT pairs are superior to the standard pair of API NC38,and UTT-Ⅲ has the most performance in all of four UTT pairs.Compared with the standard pair of API NC38,UTT-Ⅲ pair can improve the bearing capacity such as torsion strength,compression strength,tensile strength,bending strength,strength against internal and external pressure,by 24.8%,13.2%,22%,9.99%and 14.2%,respectively.The new design method of UTT pair enhances the bearing capacity of API NC38 thread,and has been applied in Changqing Drilling Company of CNPC Chuanqing Drilling Engineering Company Limited.The UTT-thread pair method is not only applicable for API series threads to improve the connection performance,but also suitable for various non-API taper connection threads to promote existing working ability such as air tightness,stress corrosion resistance,fatigue resistance et al. | Hangming Liu Yangye He Jifang Wan Lin Chen Xianzhong Yi Song Hou Yanbin Wang Dongxu He Gang Li | 2023 | Petroleum2023，9，3： | 0 |
| 15 | Reamed or unreamed intramedullary nailing for tibial fractures: a meta-analysis显示文摘ObjectiveTo 比较用中国、英语的语言在 adults.MethodsLiterature 报告在胫骨的破裂上钉方法的不同 intramedullary 的对待的效果被检索(从最早可得到的记录到2013年10月1日)从 PubMed , FMJS , CNKI ,用使随机化的控制试用( RCT )的 Wanfang 数据铰大比较并且为胫骨的破裂的治疗钉的 unreamed intramedullary 。试用的方法学的质量极其被估计,并且相关数据被提取。统计软件 Revman 5.0 被用于 12 全部的 data-analysis.ResultsA 使随机化的控制试用,包括 985 个病人(475 在 unreamed 组织并且 510 在铰大的组) ,为在这元分析的包括是合格的。元分析的结果证明在感染的报导结果的二个方法之间没有统计上重要的差别(RR = 0.64;95%CI, 0.39 ~ 1.07;P = 0.09 ) ,分隔空间症候群(RR = 1.44;95%CI, 0.8 ~ 2.41;P = 0.16 ) ,血栓(RR = 1.29;95%CI, 0.43 ~ 3.87;P = 0.64 ) ,联合的时间(WMD = 5.01;95%CI, −1.78 到 11.80;P = 0.15 ) ,推迟的联合(不属于工会)(RR = 1.56;95%CI, 0.97 ~ 2.49;P = 0.06 ) , malunion (RR = 1.75;95%CI, 1.00 ~ 3.08;P = 0.05 ) 并且膝疼痛(RR = 0.94;95%CI, 0.73 ~ 1.22;P = 0.66 ) 。但是比在铰大的组在 unreamed 组有显著地更高的固定失败率(RR = 4.29;95%CI, 2.58 ~ 7.14;P < 0.00001 ).ConclusionThere 不是重要差别在铰大并且为胫骨的破裂的处理钉的 unreamed intramedullary,而是我们的结果为他们的更低的固定失败率为关上的胫骨的破裂的处理推荐铰大的钉子。 | Yu Guangshu Lin Yanbin Wang Yu Xu Zhiqing | 2014 | Chinese Journal of Traumatology2014，17，4： | 0 |
| 16 | Colletodiphenol A,a new phenol derivative isolated from the endophytic fungus Colletotrichum capsici显示文摘A new C_(6)-C_(2)dimer phenol derivative,colletodiphenol A(1),along with two known C_(6)-C_(2)phenol derivatives(2,3)were isolated from the endophytic fungus Colletotrichum capsici related to the traditional Chinese medicine Paeonia lactiflora.Their structures were elucidated based on extensive spectroscopic data analysis,including HRESIMS,UV,IR,1D and 2D NMR.The antioxidant and anti-inflammatory activities of the isolated compounds were evaluated,but none of them displayed significant activity. | Guiyang Xia Yanbin Sun Yuzhuo Wu Huan Xia Pengcheng Lin Sheng Lin | 2021 | Asian Journal of Traditional Medicines2021，16，4： | 0 |
| 17 | Light Intensity Affects the Coloration and Structure of Chimeric Leaves of Ananas comosus var.bracteatus显示文摘Ananas comosus var.bracteatus is an important ornamental plant because of its green/white chimeric leaves.The accumulation of anthocyanin makes the leaf turn to red especially in the marginal part.However,the red fades away in summer and winter.Light intensity is one of the most important factors affecting leaf color along the seasons.In order to understand the effects of light intensity on the growth and coloration of the chimeric leaves,Ananas comosus var.bracteatus was grown under full sunlight,50%shade and 75%shade for 75 days to evaluate the concentration of pigments,the color parameters(values L^(*),a^(*),b^(*))and the morpho-anatomical variations of chimeric leaves.The results showed that a high irradiance was beneficial to keep the chimeric leaves red.However,prolonged exposure to high irradiance caused a damage,some of the leaves wrinkled and even burned.Shading instead decreased the concentration of anthocyanin and increased the concentration of chlorophyll,especially in the white marginal part of the leaves.Numerous chloroplasts were observed in the mesophyll cells of the white marginal part of the chimeric leaves under shading for 75 days.The increase in chlorophyll concentration resulted in a better growth of plants.In order to balance the growth and coloration of the leaves,approximately 50%shade is suggested to be the optimum light irradiance condition for Ananas comosus var.bracteatus in summer. | Wei Yang Yuke Lin Yanbin Xue Meiqin Mao Xuzixing Zhou Hao Hu Jiawen Liu Lijun Feng Huiling Zhang Jiaheng Luo Jun Ma | 2022 | Phyton-International Journal of Experimental Botany2022，91，2： | 0 |
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