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| 1 | Improvedendoscopicretrogradecholangiopancreatographybrushincreases diagnosticyieldofmalignantbiliarystrictures显示文摘AIM: To determine if a new brush design could im-prove the diagnostic yield of biliary stricture brushings. METHODS: Retrospective chart review was performed of all endoscopic retrograde cholangiopancreatography procedures with malignant biliary stricture brushing between January 2008 and October 2012. A standard wire-guided cytology brush was used prior to proto-col implementation in July 2011, after which, a new 9 French wire-guided cytology brush(Infinity sampling device, US Endoscopy, Mentor, OH) was used for all cases. All specimens were reviewed by blinded pa-thologists who determined whether the sample waspositive or negative for malignancy. Cellular yield was quantified by describing the number of cell clusters seen. RESULTS: Thirty-two new brush cases were compared to 46 historical controls. Twenty-five of 32 (78%) cases in the new brush group showed abnormal cellular find-ings consistent with malignancy as compared to 17 of 46(37%) in the historical control group(P = 0.0003). There was also a significant increase in the average number of cell clusters of all sizes(21.1 vs 9.9 clusters, P = 0.0007) in the new brush group compared to his-torical controls. CONCLUSION: The use of a new brush design for brush cytology of biliary strictures shows increased di-agnostic accuracy, likely due to improved cellular yield, as evidenced by an increase in number of cellular clus-ters obtained. | Shieh FK Luong-Player A Khara HS Liu H Lin F Shellenberger MJ Johal AS Diehl DL | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 4 |
| 2 | Deficiency in ClC - 3 chloride channels prevents rat aortic smooth muscle cell proliferation显示文摘 | Wang GL Wang XR Lin MJ | 2002 | Circ Res2002，91，10： | 2 |
| 3 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 4 | Effect of thermal stimulation on upper extremity motor recovery 3 months after stroke显示文摘 | WU HC LIN YC HSU MJ | 2010 | Stroke2010，41，10： | 1 |
| 5 | Down-regulation of L-type calcium channel and sarcopasmic reticular Ca2+-ATPase mRNA in human atrial fibrillation without significant change in the mRNA of ryanodine receptor,calsequestrin and phospholamban-an insight into the mechanism of atrial electrical remodeling显示文摘 | Lai LP Su MJ Lin JL | 1999 | JACC1999，33，： | 1 |
| 6 | Activation of c-Jun N-Terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition 显示文摘 | Savage MJ Lin YG Ciallella JR | 2002 | Neurosci2002，22，9： | 1 |
| 7 | The prevalence of dementia in the People's Republic of China:a systematic analysis of 1980-2004 studies显示文摘 | Dong MJ Peng B Lin XT | 2007 | Age Ageing2007，36，6： | 1 |
| 8 | Enhanced adhesion of monocytes via reverse signaling triggered by decoy receptor 3显示文摘 | Hsu MJ Lin WW Tsao WC | 2004 | Exp Cell Res2004，292，2： | 1 |
| 9 | Lrrk 2 G2385R is an ancestral risk factor for Parkinson 's disease in Asia 显示文摘 | Farrer MJ Stone Jr Lin CH | 2007 | Parkinsonism Relat Disord2007，13，： | 1 |
| 10 | Efficacy and safety of methotrexate therapy for juvenile rheumatoid arthritis显示文摘 | Lin YT Tsai MJ Wang LH | 2000 | J Formos Med Assoc2000，99，8： | 1 |
| 11 | Performance of high-risk human papillomavirus DNA testing as a primary screen for cervical cancer:apooled analysis of individual patient data from 17population-based studies from China显示文摘 | Zhao FH Lin MJ Chen F | 2010 | Lancet Oncol2010，11，12： | 1 |
| 12 | Luteolin induces mieroRNA-132 expression and modulates neurite outgrowth in PC12 ceils 显示文摘 | Lin LF Chiu SP Wu MJ | 2012 | PLoS One2012，7，43： | 1 |
| 13 | Neurotrophic and cytoprotective action of luteolin in PC12 cells through ERK-dependent induction of Nrf2-driven HO-1 expression显示文摘 | Lin CW Wu MJ Liu IY Su JD Yen JH | 2010 | J Agric Food Chem2010，58，7： | 1 |
| 14 | Neurocognitive improvement after ca-rotid artery stenting in patients with chronic internal carotid artery oc-clusion and cerebral ischemia显示文摘 | Lin MS Chiu MJ Wu YW | | 0，，： | 1 |
| 15 | Activation of c-Jun N-Terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition显示文摘 | Savage MJ Lin YG Ciallella JR | 2002 | J Neurosci2002，22，9： | 1 |
| 16 | The prevalence of dementia in the Peoples' Republic of China:a systematic analysis of 1980-2004 studies 显示文摘 | Dong MJ Peng B Lin XT | 2007 | Age Ageing2007，36，6： | 1 |
| 17 | Lateral meniscus root tear and meniscus extrusion with anterior cruciate ligament tear显示文摘 | Brody JM Lin HM Hulstyn MJ | | 0，，3： | 1 |
| 18 | 图像引导胸腔镜手术同步定位和切除肺小结节显示文摘肺小结节在放射科通过CT定位后前往手术室进行手术切除,分步进行的方法存在很大的风险,如气胸、血胸、定位钩脱落等。从理论上讲,这些问题可通过配备适合定位系统的复合手术室中进行同步定位和胸腔镜手术(VATS)来规避。本研究纳入2016年10月至2017年1月12例出现孤立性肺小结节进行图像引导胸腔镜手术(iVATS)的患者,分析同步进行定位后行胸腔镜手术的可行性。 | 施琴朗(编译) Hsieh MJ Fang HY Lin CC | 2021 | 中华医学杂志2021，101，33： | 1 |
| 19 | Changes in the mRNA levels of delayed rectifier potassium channels in human atrial fibrillation显示文摘 | Lai LP Su MJ Lin JL | 1999 | Cardiology1999，92，： | 1 |
| 20 | Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization显示文摘 | Donovan MJ Lin MI Wiegn P | 2000 | Development2000，127，： | 1 |
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