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| 1 | ABA-Mediated Inhibition of Germination Is Related to the Inhibition of Genes Encoding Cell-Wall Biosynthetic and Architecture: Modifying Enzymes and Structural Proteins in Medicago truncatula Embryo Axis显示文摘胚根出现和储备动员是被认为控制萌芽的二个不同计划。两个节目被 abscissic 酸(骆驼毛的织物) 影响,但是这荷尔蒙怎么控制种子萌芽,仍然糟糕被知道。Phenotypic 和 Medicago truncatula 的胚胎轴的显微镜的观察在 10 在处于有丝分裂的抑制状况的萌芽期间被触发 ? M oryzalin 证明房间分割没被要求允许胚根出现。镇压减少性的杂交证明在胚胎轴的超过 10% 起来调整的基因编码了与房间墙生合成有关的蛋白质。-expansins, pectin-esterase, xylogucan-endotransglycosidase,纤维素 synthase,和 extensins 的表示在种子的胚胎轴被监视在水上发芽了,经常、临时的骆驼毛的织物。在在控制并且强烈的萌芽的结束由骆驼毛的织物禁止了以前,这些基因是 overexpressed。在种子回来在水上被转移并且继续了到萌芽以后,表示在临时处理的 ABA 被重建。这作为贡献者证明这些基因到萌芽的结束并且加强在胚胎轴在与房间扩大的关系松开并且改变的房间墙是在萌芽的一个决定因素特征的想法。我们的结果也证明那件骆驼毛的织物通过胚根出现的控制控制萌芽,也就是由禁止房间墙松开和扩大。 | Christine Gimeno-Gilles Eric Lelievre Laure Viau Mustafa Malik-Ghulam Claudie Ricoult Andreas Niebel Nathalie Leduc Anis M. Limami | 2009 | Molecular Plant2009，2，1： | 8 |
| 2 | 104例肾综合征出血热远期随访研究显示文摘目的:探讨肾综合征出血热(HFRS)患者临床缓解后有无远期肾损害及其他后遗症。方法:随访HFRS恢复患者104例(HFRS组),询问病史,进行常规体检,检查血常规、尿常规、肝肾功能、血脂、胸透或胸片、心电图、肝胆脾及双肾B超、汉坦病毒(HV)IgG抗体。同时选择同一地区,性别、年龄类似,无HFRS病史的84例作为对照组,其中HV-肾综合征出血热病毒IgG抗体阳性的患者作为HV隐性感染组,HV-IgG抗体肾综合征出血热病毒IgG抗体阴性的患者者作为HV非感染组,均进行相同检查,对3组的检查结果进行对比研究分析。另外随机选择无肾综合征出血热病史的慢性肾脏疾病患者血清43份,初步探讨慢性肾脏疾病与汉坦病毒感染之间的关系。结果:104例HFRS恢复患者中97例(93.27%)HV-IgG抗体阳性,对照组23例(27.38%)HV-IgG抗体阳性。HFRS组104例中8例(7.69%)尿蛋白阳性(≥+),高于HV非感染组(0%),两组进行比较,有显著性统计学差异(P=0.027)。HFRS组有垂体功能减退1例;慢性肾炎、肾移植患者1例。结论:大部分HFRS恢复患者HV-IgG抗体可长期存在。HFRS急性感染后,远期肾损害发生率明显高于正常人群,是否与HV的持续性感染有关,值得进一步的研究。 | 张礼丙 熊勇 吴晓燕 董盛丰 刘书 谢其祥 彭波 肖书渊 James W LeDuc | 2010 | 武汉大学学报(医学版)2010，31，2： | 3 |
| 3 | Activator for peroxide bleaching of mechanical pulp显示文摘 | Celine Leduc | | Appita Journal0，，4： | 2 |
| 4 | Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension显示文摘 | Eric D. Austin Lijiang Ma Charles LeDuc Erika Berman Rosenzweig Alain Borczuk John A. Phillips Teresa Palomero Pavel Sumazin Hyunjae R. Kim Megha H. Talati James West James E. Loyd Wendy K. Chung | 2012 | Circulation: Cardiovascular Genetics2012，，3： | 2 |
| 5 | Is Ulnar Nerve Transposition Beneficial During Open Reduction Internal Fixation of Distal Humerus Fractures?显示文摘 | Ryan C Chen David J Harris Stephane Leduc Joseph J Borrelli Paul Tornetta William M Ricci | 2010 | Journal of Orthopaedic Trauma2010，，7： | 2 |
| 6 | Verification of security protocols using LOTOS-method and application 显示文摘 | Leduc G Gereau F | 2000 | Computer Communications2000，23，12： | 2 |
| 7 | AIF-regulated oxidative phosphorylation supports lung cancer development显示文摘Cancer is a major and still increasing cause of death in humans. Most cancer cells have a fundamentally different metabolic profile from that of normal tissue. This shift away from mitochondrial ATP synthesis via oxidative phosphorylation towards a high rate of glycolysis, termed Warburg effect, has long been recognized as a paradigmatic hallmark of cancer, supporting the increased biosynthetic demands of tumor cells. Here we show that deletion of apoptosis-inducing factor (AIF) in a Kras^G12D-driven mouse lung cancer model resulted in a marked survival advantage, with delayed tumor onset and decreased malignant progression. Mechanistically, Aif deletion leads to oxidative phosphorylation (OXPHOS) deficiency and a switch in cellular metabolism towards glycolysis in non-transformed pneumocytes and at early stages of tumor development. Paradoxically, although Aif-deficient cells exhibited a metabolic Warburg profile, this bioenergetic change resulted in a growth disadvantage of Kras^G12D-driven as well as Kras wild-type lung cancer cells. Cell-autonomous re-expression of both wild-type and mutant AIF (displaying an intact mitochondrial, but abrogated apoptotic function) in Aif-knockout Kras^G12D mice restored OXPHOS and reduced animal survival to the same level as AIF wild-type mice. In patients with non-small cell lung cancer, high AIF expression was associated with poor prognosis. These data show that AIF-regulated mitochondrial respiration and OXPHOS drive the progression of lung cancer. | Shuan Rao Laura Mondragon Blanka Pranjic Toshikatsu Hanada Gautier Stoll Thomas Kocher Peng Zhang Alexander Jais Alexander Lercher Andreas Bergthaler Daniel Schramek Katharina Haigh Valentina Sica Marion Leduc Nazanine Modjtahedi Tsung-Pin Pai Masahiro Onji Iris Uribesalgo Reiko Hanada Ivona Kozieradzki Rubina Koglgruber Shane J. Cronin Zhigang She Franz Quehenberger Helmut Popper Lukas Kenner Jody J. Haigh Oliver Kepp Malgorzata Rak Kaican Cai Guido Kroemer Josef M. Penninger | 2019 | Cell Research2019，29，7： | 2 |
| 8 | Living free radical polymerization and dendritic polymers 显示文摘 | FRECHET J M J LEDUC M R WEIMER M | 1997 | Am Chem Soc Div Polym Chem Prepr1997，38，1： | 1 |
| 9 | First evidence of a calcium transient in flowering plants at fertilization显示文摘 | Digonnet Aldon Leduc Dumas Rougier | 1997 | Development1997，124，： | 1 |
| 10 | Bridging the gap: a comparison of the professional nursing values of students, new graduates, and seasoned professionals显示文摘 | I LeDuc K Kotzer A | 2009 | Nuts Edue Persp2009，30，50： | 1 |
| 11 | Direct investiga- tion of intraeellular presence of gold nanoparticles via photother- mal hetemdyne imaging 显示文摘 | LEDUC C JUNG J M CARNEY R P | 2011 | Acs Nano2011，5，4： | 1 |
| 12 | Mercury localization and speciation in plants grown hydroponically or in a natural environment显示文摘 | Carrasco-Gil S Siebner H LeDuc DL | 2013 | Environmental Science & Technology2013，47，7： | 1 |
| 13 | Evolution of volatile odorous compounds during the storage of European seabass (Dicentrarchus labrax)显示文摘 | Francois Leduc Pascal Tournayre Nathalie Kondjoyan | 2012 | Food Chemistry2012，，131： | 1 |
| 14 | Detection of Acidithiobacillus ferrooxidans in acid mine drainage environments using fluorescent in situ hybridization (FISH)显示文摘 | MAHMOUD KK LEDUC LG FERRONI GD | 2005 | Journal of Microbiological Methods2005，61，： | 1 |
| 15 | Dalteparin for the prevention of recurrence of placental-mediated complications of pregnancy in women without thrombophilia:a pilot randomized controlled trial显示文摘 | Rey E Garneau P David M Gauthier R Leduc L Michon N | 2009 | J Thromb Haemost2009，7，1： | 1 |
| 16 | Damage in hot rolling work rolls显示文摘 | Rafael Colás Jorge Ram??rez Ignacio Sandoval Julio C Morales Luis A Leduc | 1999 | Wear1999，，1： | 1 |
| 17 | Catecholamine levels in portal, hepatic, and systemic venous blood in portal hypertension显示文摘 | Joly JG Leduc J Bernier J | 1967 | Lan- cet1967，2，： | 1 |
| 18 | Activemanagement of the third stage of labour:prevention andtreatment of postpartum hemorrhage显示文摘 | LEDUC D SENIKAS V LALONDE A B | 2009 | J Obstet Gynaecol Can2009，31，10： | 1 |
| 19 | Freshness characterization of whiting( Merlangius merlangus)using an SPEM -GC-MS method and a statistical muhivariate approach 显示文摘 | Duflos G Leduc F Nguessan A | 2010 | Journal of the Science of Food and Agriculture2010，90，15： | 1 |
| 20 | The use of xylanases in kraft pulp bleaching:areview 显示文摘 | Leduc D C Valade J L | 1994 | Tappi Journal1994，77，5： | 1 |
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